Uqcrh (ubiquinol-cytochrome c reductase hinge protein) - Rat Genome Database

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Gene: Uqcrh (ubiquinol-cytochrome c reductase hinge protein) Rattus norvegicus
Analyze
Symbol: Uqcrh
Name: ubiquinol-cytochrome c reductase hinge protein
RGD ID: 1305987
Description: Predicted to enable quinol-cytochrome-c reductase activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Part of respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency. Orthologous to several human genes including UQCRH (ubiquinol-cytochrome c reductase hinge protein); PARTICIPATES IN electron transport chain pathway; Alzheimer's disease pathway; Huntington's disease pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: complex III subunit 6; complex III subunit VIII; cytochrome b-c1 complex subunit 6, mitochondrial; cytochrome c1 non-heme 11 kDa protein; LOC366448; MGC109658; mitochondrial hinge protein; ubiquinol-cytochrome c reductase complex 11 kDa protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85134,782,687 - 134,790,882 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5134,782,255 - 134,790,926 (-)EnsemblGRCr8
mRatBN7.25129,545,978 - 129,554,173 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5129,545,984 - 129,554,242 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5132,162,175 - 132,170,197 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05133,917,061 - 133,925,081 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05133,939,196 - 133,947,216 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05134,919,040 - 134,927,235 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5134,919,044 - 134,927,235 (-)Ensemblrn6Rnor6.0
Rnor_5.05138,702,773 - 138,710,968 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45136,255,481 - 136,263,676 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5128,076,102 - 128,084,160 (-)NCBICelera
RGSC_v3.15136,260,706 - 136,268,898 (+)NCBI
Cytogenetic Map5q35NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(+)-schisandrin B  (EXP)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
5-methyl-4-oxido-2-pyrazin-4-iumcarboxylic acid  (ISO)
acetamide  (EXP)
aldehydo-D-glucosamine  (ISO)
ampicillin  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenic trichloride  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
beta-D-glucosamine  (ISO)
bilirubin IXalpha  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bleomycin A2  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
chloropicrin  (ISO)
chromium(6+)  (ISO)
clofibric acid  (EXP)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
dieldrin  (EXP)
disulfiram  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenthion  (ISO)
flutamide  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
heptachlor  (EXP)
hydrogen peroxide  (ISO)
isoniazide  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (EXP)
methidathion  (ISO)
metronidazole  (EXP)
mitoxantrone  (ISO)
Monobutylphthalate  (ISO)
neomycin  (EXP)
ochratoxin A  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
perfluorododecanoic acid  (EXP)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
selenium atom  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
vancomycin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
4. Role of the hinge protein in the electron transfer between cardiac cytochrome c1 and c. Equilibrium constants and kinetic probes. Kim CH, etal., J Biol Chem. 1987 Jun 15;262(17):8103-8.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Mass spectrometric characterization of mitochondrial electron transport complexes: subunits of the rat heart ubiquinol-cytochrome c reductase. Sun G, etal., J Mass Spectrom 2003 May;38(5):531-9.
Additional References at PubMed
PMID:12477932   PMID:12865426   PMID:14651853   PMID:15489334   PMID:16120479   PMID:16854843   PMID:18614015   PMID:20833797   PMID:28844695   PMID:35352799  


Genomics

Comparative Map Data
Uqcrh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85134,782,687 - 134,790,882 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5134,782,255 - 134,790,926 (-)EnsemblGRCr8
mRatBN7.25129,545,978 - 129,554,173 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5129,545,984 - 129,554,242 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5132,162,175 - 132,170,197 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05133,917,061 - 133,925,081 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05133,939,196 - 133,947,216 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05134,919,040 - 134,927,235 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5134,919,044 - 134,927,235 (-)Ensemblrn6Rnor6.0
Rnor_5.05138,702,773 - 138,710,968 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45136,255,481 - 136,263,676 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5128,076,102 - 128,084,160 (-)NCBICelera
RGSC_v3.15136,260,706 - 136,268,898 (+)NCBI
Cytogenetic Map5q35NCBI
UQCRH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38146,303,698 - 46,316,776 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl146,300,900 - 46,316,796 (+)Ensemblhg38GRCh38
GRCh37146,769,370 - 46,782,448 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36146,541,967 - 46,555,035 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34146,481,427 - 46,494,465NCBI
Celera145,056,760 - 45,069,814 (+)NCBICelera
Cytogenetic Map1p33NCBI
HuRef144,885,225 - 44,898,088 (+)NCBIHuRef
CHM1_1146,886,405 - 46,899,453 (+)NCBICHM1_1
T2T-CHM13v2.0146,180,920 - 46,193,993 (+)NCBIT2T-CHM13v2.0
Uqcrh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394115,924,162 - 115,932,267 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4115,924,162 - 115,932,268 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384116,066,965 - 116,075,070 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4116,066,965 - 116,075,071 (-)Ensemblmm10GRCm38
MGSCv374115,739,570 - 115,747,675 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364115,564,897 - 115,572,980 (-)NCBIMGSCv36mm8
Celera4114,805,226 - 114,813,332 (-)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.1NCBI
LOC102022061
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495546411,963,706 - 11,975,959 (-)NCBIChiLan1.0ChiLan1.0
LOC100984974
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21180,491,655 - 180,504,541 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11179,633,240 - 179,646,124 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0145,606,924 - 45,619,811 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1146,961,538 - 46,975,055 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl146,961,538 - 46,975,055 (+)EnsemblpanPan2panpan1.1
UQCRH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11514,082,954 - 14,092,690 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1514,206,037 - 14,215,760 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01514,235,841 - 14,245,565 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1514,235,829 - 14,245,492 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11514,037,133 - 14,046,855 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01514,105,635 - 14,115,358 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01514,175,098 - 14,184,823 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
UQCRH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.16165,123,915 - 165,134,375 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26152,603,249 - 152,613,725 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UQCRH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12086,479,930 - 86,484,783 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603330,502,275 - 30,507,160 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101718708
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249062,217,180 - 2,226,075 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249062,217,142 - 2,226,075 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
LOC116898210
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1139,747,161 - 39,755,112 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Uqcrh
89 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:28
Interacting mature miRNAs:31
Transcripts:ENSRNOT00000016751
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
2303586Gluco52Glucose level QTL 522blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)5100826632145826632Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5130678987145274255Rat
7365049Bp359Blood pressure QTL 359arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133308734140009902Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5134369218156289444Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5110770739155770739Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)592583776137583776Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)598972960143972960Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
2303618Vencon1Ventilatory control QTL 13.8respiration trait (VT:0001943)oxygen consumption (CMO:0002169)5100826632145826632Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111236572156236572Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)594034903139034903Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5125969677156302135Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)570969494136328156Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)592881678137881678Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat

Markers in Region
RH129777  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25129,546,053 - 129,546,236 (+)MAPPERmRatBN7.2
Rnor_6.05134,919,116 - 134,919,298NCBIRnor6.0
Rnor_5.05138,702,849 - 138,703,031UniSTSRnor5.0
RGSC_v3.45136,263,418 - 136,263,600UniSTSRGSC3.4
Celera5128,076,178 - 128,076,360UniSTS
RH 3.4 Map5837.1UniSTS
Cytogenetic Map5q36UniSTS
BE108773  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25129,547,404 - 129,547,582 (+)MAPPERmRatBN7.2
Rnor_6.05134,920,467 - 134,920,644NCBIRnor6.0
Rnor_5.05138,704,200 - 138,704,377UniSTSRnor5.0
RGSC_v3.45136,262,072 - 136,262,249UniSTSRGSC3.4
Celera5128,077,470 - 128,077,647UniSTS
RH 3.4 Map5835.7UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001009480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC110367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC086954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000016751   ⟹   ENSRNOP00000016751
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5134,782,693 - 134,790,851 (-)Ensembl
mRatBN7.2 Ensembl5129,545,984 - 129,554,142 (-)Ensembl
Rnor_6.0 Ensembl5134,919,044 - 134,927,235 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111417   ⟹   ENSRNOP00000080974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5129,548,277 - 129,554,242 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118108   ⟹   ENSRNOP00000085348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5134,782,255 - 134,790,926 (-)Ensembl
mRatBN7.2 Ensembl5129,546,039 - 129,554,242 (-)Ensembl
RefSeq Acc Id: NM_001009480   ⟹   NP_001009480
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85134,782,687 - 134,790,882 (-)NCBI
mRatBN7.25129,545,978 - 129,554,173 (-)NCBI
Rnor_6.05134,919,040 - 134,927,235 (-)NCBI
Rnor_5.05138,702,773 - 138,710,968 (-)NCBI
RGSC_v3.45136,255,481 - 136,263,676 (+)RGD
Celera5128,076,102 - 128,084,160 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001009480 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH86954 (Get FASTA)   NCBI Sequence Viewer  
  EDL90294 (Get FASTA)   NCBI Sequence Viewer  
  Q5M9I5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001009480   ⟸   NM_001009480
- UniProtKB: Q5M9I5 (UniProtKB/Swiss-Prot),   A6JZ59 (UniProtKB/TrEMBL),   A0A8L2Q828 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016751   ⟸   ENSRNOT00000016751
Ensembl Acc Id: ENSRNOP00000085348   ⟸   ENSRNOT00000118108
Ensembl Acc Id: ENSRNOP00000080974   ⟸   ENSRNOT00000111417
Protein Domains
Ubiquinol-cytochrome C reductase hinge

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M9I5-F1-model_v2 AlphaFold Q5M9I5 1-89 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693926
Promoter ID:EPDNEW_R4451
Type:initiation region
Name:Uqcrh_1
Description:ubiquinol-cytochrome c reductase hinge protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05134,927,272 - 134,927,332EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305987 AgrOrtholog
BioCyc Gene G2FUF-40267 BioCyc
BioCyc Pathway PWY-3781 [aerobic respiration I (cytochrome c)] BioCyc
  PWY-7279 [aerobic respiration II (cytochrome c) (yeast)] BioCyc
BioCyc Pathway Image PWY-3781 BioCyc
  PWY-7279 BioCyc
Ensembl Genes ENSRNOG00000012550 Ensembl
Gene3D-CATH 1.10.287.20 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7368408 IMAGE-MGC_LOAD
InterPro Cyt_b-c1_6 UniProtKB/Swiss-Prot
  Ubol_cytC_Rdtase_hinge_dom UniProtKB/Swiss-Prot
  Ubol_cytC_Rdtase_hinge_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:366448 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109658 IMAGE-MGC_LOAD
NCBI Gene 366448 ENTREZGENE
PANTHER CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL UniProtKB/Swiss-Prot
  PTHR15336 UniProtKB/Swiss-Prot
Pfam UCR_hinge UniProtKB/Swiss-Prot
PhenoGen Uqcrh PhenoGen
PIRSF Bc1_11K UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012550 RatGTEx
Superfamily-SCOP SSF81531 UniProtKB/Swiss-Prot
UniProt A0A8I6A162_RAT UniProtKB/TrEMBL
  A0A8L2Q828 ENTREZGENE, UniProtKB/TrEMBL
  A6JZ59 ENTREZGENE, UniProtKB/TrEMBL
  Q5M9I5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Uqcrh  ubiquinol-cytochrome c reductase hinge protein  Uqcrh_predicted  ubiquinol-cytochrome c reductase hinge protein (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Uqcrh_predicted  ubiquinol-cytochrome c reductase hinge protein (predicted)      Symbol and Name status set to approved 70820 APPROVED