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Gene: Suds3 (SIN3A corepressor complex component SDS3) Rattus norvegicus

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Symbol:

Suds3

Name:

SIN3A corepressor complex component SDS3 (Ensembl:SDS3 homolog, SIN3A corepressor complex component)

RGD ID:

1305986

Description:

Predicted to enable histone deacetylase binding activity and identical protein binding activity. Predicted to contribute to histone deacetylase activity. Predicted to be involved in chromatin remodeling and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within blastocyst hatching and negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of Sin3-type complex. Orthologous to human SUDS3 (SDS3 homolog, SIN3A corepressor complex component); INTERACTS WITH bisphenol A; Butylbenzyl phthalate; gentamycin.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC360819; RGD1305986; SDS3 homolog, SIN3A corepressor complex component; similar to FLJ00052 protein; sin3 histone deacetylase corepressor complex component SDS3; suppressor of defective silencing 3 homolog; suppressor of defective silencing 3 homolog (S. cerevisiae)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	45,137,964 - 45,160,413 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	45,138,400 - 45,160,411 (+)	Ensembl				GRCr8
mRatBN7.2	12	39,477,181 - 39,499,633 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	39,477,568 - 39,499,628 (+)	Ensembl				mRatBN7.2
Rnor_6.0	12	45,199,012 - 45,221,507 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	45,199,577 - 45,221,512 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	47,018,834 - 47,040,899 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	40,668,710 - 40,690,008 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	41,116,885 - 41,139,337 (+)	NCBI		Celera
RGSC_v3.1	12	40,451,775 - 40,553,269 (+)	NCBI
Cytogenetic Map	12	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

atrazine (ISO)

bisphenol A (EXP,ISO)

bortezomib (ISO)

Butylbenzyl phthalate (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

corosolic acid (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

ethanol (ISO)

fenthion (ISO)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

gentamycin (EXP)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methidathion (ISO)

methoxychlor (EXP)

methylphenidate (ISO)

ozone (ISO)

PCB138 (EXP)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

propiconazole (ISO)

resveratrol (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blastocyst hatching (ISO)

chromatin remodeling (IEA,ISO)

DNA-templated transcription (IEA)

negative regulation of DNA-templated transcription (ISO)

negative regulation of transcription by RNA polymerase II (IBA,IEA,ISO)

regulation of gene expression (IEA)

substantia nigra development (ISO)

Cellular Component

nuclear body (IEA,ISO)

nucleoplasm (IEA)

nucleus (IEA,ISO)

Sin3-type complex (IBA,ISO)

Molecular Function

enzyme binding (IEA,ISO)

histone deacetylase activity (IEA,ISO)

histone deacetylase binding (IBA,ISO)

identical protein binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11909966	PMID:12477932	PMID:15489224	PMID:21239494	PMID:22783022	PMID:22926577	PMID:27869233

Genomics

Comparative Map Data

Suds3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	45,137,964 - 45,160,413 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	45,138,400 - 45,160,411 (+)	Ensembl				GRCr8
mRatBN7.2	12	39,477,181 - 39,499,633 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	39,477,568 - 39,499,628 (+)	Ensembl				mRatBN7.2
Rnor_6.0	12	45,199,012 - 45,221,507 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	45,199,577 - 45,221,512 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	47,018,834 - 47,040,899 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	40,668,710 - 40,690,008 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	41,116,885 - 41,139,337 (+)	NCBI		Celera
RGSC_v3.1	12	40,451,775 - 40,553,269 (+)	NCBI
Cytogenetic Map	12	q16	NCBI

SUDS3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	118,376,555 - 118,418,033 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	118,376,531 - 118,418,033 (+)	Ensembl			hg38	GRCh38
GRCh37	12	118,814,360 - 118,855,838 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	117,298,741 - 117,340,223 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	12	118,447,308 - 118,488,791 (+)	NCBI		Celera
Cytogenetic Map	12	q24.23	NCBI
HuRef	12	115,823,578 - 115,865,286 (+)	NCBI		HuRef
CHM1_1	12	118,782,210 - 118,823,650 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	118,363,824 - 118,405,300 (+)	NCBI		T2T-CHM13v2.0

Suds3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	117,229,743 - 117,257,980 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	117,229,745 - 117,254,178 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	117,091,678 - 117,115,993 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	117,091,680 - 117,116,113 (-)	Ensembl			mm10	GRCm38
MGSCv37	5	117,541,689 - 117,566,002 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	117,352,714 - 117,376,963 (-)	NCBI		MGSCv36	mm8
Celera	5	114,181,513 - 114,205,973 (-)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	56.88	NCBI

Suds3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	12,981,194 - 13,017,194 (-)	Ensembl
ChiLan1.0	NW_004955455	12,981,899 - 13,017,194 (-)	NCBI	ChiLan1.0	ChiLan1.0

SUDS3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	126,443,284 - 126,484,583 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	126,439,663 - 126,480,962 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	115,957,736 - 115,999,217 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	119,336,258 - 119,377,030 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	119,336,258 - 119,377,030 (+)	Ensembl			panPan2	panpan1.1

SUDS3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	14,716,759 - 14,749,475 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	14,716,562 - 15,019,622 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	14,715,947 - 14,748,653 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	14,978,714 - 15,011,641 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	14,978,505 - 15,281,788 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	14,943,664 - 14,976,339 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	15,016,048 - 15,048,712 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	15,057,467 - 15,090,172 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Suds3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	147,580,224 - 147,614,345 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936668	2,077,729 - 2,113,361 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936668	2,078,783 - 2,113,154 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SUDS3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	34,156,339 - 34,317,081 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	34,241,220 - 34,317,092 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	36,413,480 - 36,447,476 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SUDS3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	113,720,724 - 113,763,582 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	113,720,813 - 113,760,010 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	131,339,711 - 131,383,403 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Suds3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624747	15,104,630 - 15,138,809 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Suds3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	36,712,846 - 36,735,849 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Suds3
149 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	185
Count of miRNA genes:	127
Interacting mature miRNAs:	146
Transcripts:	ENSRNOT00000001504, ENSRNOT00000075646
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	24805022	52308831	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	11200494	52308831	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	50386405	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	25989355	52308831	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1300162	Bp188	Blood pressure QTL 188	3.19		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	37764145	51558799	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18473041	52308831	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15264248	52308831	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200497	52308831	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	11743528	52308831	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
1600386	Calcic2	Intracellular calcium level QTL 2		0.001	platelet physiology trait (VT:0005464)	platelet intracellular calcium level (CMO:0000922)	12	33700432	46784661	Rat
1300175	Cm5	Cardiac mass QTL 5	3.78		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	33700432	51558799	Rat
1556747	Calcic1	Intracellular calcium level QTL 1		3.6	platelet calcium amount (VT:0010500)	platelet intracellular calcium level (CMO:0000922)	12	33700432	46784661	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	17464979	46784661	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	16187438	52308831	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	49212240	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	16135029	52308831	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	51213550	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	11200494	52308831	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	11200494	52308831	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18473041	52308831	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2747694	47747694	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	3087180	48087180	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	16135029	52308831	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
631543	Bp83	Blood pressure QTL 83	5.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	44139558	52308831	Rat

Markers in Region

RH134780

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	39,498,579 - 39,498,772 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	45,220,454 - 45,220,646	NCBI	Rnor6.0
Rnor_5.0	12	47,039,849 - 47,040,041	UniSTS	Rnor5.0
RGSC_v3.4	12	40,689,585 - 40,689,777	UniSTS	RGSC3.4
Celera	12	41,138,284 - 41,138,476	UniSTS
RH 3.4 Map	12	725.3	UniSTS
Cytogenetic Map	12	q16	UniSTS

RH141303

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	39,499,362 - 39,499,560 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	45,221,237 - 45,221,434	NCBI	Rnor6.0
Rnor_5.0	12	47,040,632 - 47,040,829	UniSTS	Rnor5.0
RGSC_v3.4	12	40,690,368 - 40,690,565	UniSTS	RGSC3.4
Celera	12	41,139,067 - 41,139,264	UniSTS
RH 3.4 Map	12	730.5	UniSTS
Cytogenetic Map	12	q16	UniSTS

AI500967

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	12	45,145,047 - 45,145,259 (+)	Marker Load Pipeline
mRatBN7.2	12	39,484,264 - 39,484,475 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	45,206,096 - 45,206,306	NCBI	Rnor6.0
Rnor_5.0	12	47,025,491 - 47,025,701	UniSTS	Rnor5.0
RGSC_v3.4	12	40,675,270 - 40,675,480	UniSTS	RGSC3.4
Celera	12	41,123,969 - 41,124,179	UniSTS
Cytogenetic Map	12	q16	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001431820	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431821	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431822	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431823	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431824	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001080131	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090182	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_341092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001840701	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001845696	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC086340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000075646 ⟹ ENSRNOP00000067032

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	45,138,476 - 45,160,411 (+)	Ensembl
mRatBN7.2 Ensembl	12	39,477,568 - 39,499,628 (+)	Ensembl
Rnor_6.0 Ensembl	12	45,199,577 - 45,221,512 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000117681 ⟹ ENSRNOP00000093128

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	45,138,400 - 45,160,411 (+)	Ensembl
mRatBN7.2 Ensembl	12	39,477,568 - 39,498,866 (+)	Ensembl

RefSeq Acc Id:

XM_039090182 ⟹ XP_038946110

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	45,144,031 - 45,160,413 (+)	NCBI
mRatBN7.2	12	39,483,248 - 39,499,633 (+)	NCBI

RefSeq Acc Id:

XM_341092 ⟹ XP_341093

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	45,137,964 - 45,160,413 (+)	NCBI
mRatBN7.2	12	39,477,181 - 39,499,633 (+)	NCBI
Rnor_6.0	12	45,199,012 - 45,221,507 (+)	NCBI
Rnor_5.0	12	47,018,834 - 47,040,899 (+)	NCBI
RGSC_v3.4	12	40,668,710 - 40,690,008 (+)	RGD

Sequence:

show sequence

CCACACACTCCGGCTGTCCAGGCTTCCAAGCCCACCACGGGGACAGTTTATGTCATTCACCTGC
TTGAATCAGACCATGCTACCTAGACAGGGCTTTGCAAAGCCTCCGCCCATCAGGTCGCATCGAT
ACACTTTAGTTTTGACTCCAGGCGCCGCCTGGTGGCCGTTTCCGGAAGTGTCCTCCCAACCTCC
GGGTCCTGACTGCGGGCACGGCTGCCCATGGATATGCCTGACCCCAGAGACCCCTGCCTTCGCC
CCTCCCCCGTGGCCGATTGAGGATTCATAAGACAGCGATGACGACGCTGCTGTGTCAGAGAACG
TGGAGCCCGGCGTCTCCGCCACTCCCTCGAGGACGGCTGGATCAGGCTGTCACCGGGCAGCCTA
CGACCCGGAAGTAGCCCGGTGCGCGAGGCCCCCGTTGCCCAGCGCGGGCGCCGGGGGCGGAGCT
CGGCGCCGAGGCAGACCGGGTGTCCGAGGCTCCGGCTGCGCGAGGTGGGGGCTGTCCGGGGCGC
AGCCAGGCGGCCGCGATCTCCGCGGGACACGCTCCGCTGCGGCCCGAGGCGGCGACATGAGCGC
CGCGGGGCTGCTGGCTCCGGCGCCCGCTCCGGCTGCAGCGCCGCCGGCCCCGGAGTACTACCCC
GAGGACGACGAGGAGCTGGAGAGCGTCGAGGACGACGAGCGCAGCTGCCGGGGCCGAGAGTCCG
ACGAAGACACTGAGGATGCCAGTGAGACCGACCTGGCTAAGCACGATGAGGAAGACTACGTGGA
GATGAAGGAACAGATGTACCAGGACAAACTGGCCTCTCTGAAGAGGCAGCTGCAGCAGCTGCAG
GAAGGTACGTTACAGGAATATCAGAAGAGGATGAAGAAGCTGGACCAGCAGTACAGAGAGAGGA
TCCGGAATGCAGAACTCTTCCTCCAGCTAGAAACGGAGCAGGTGGAAAGGAATTACATTAAGGA
GAAGAAGGCGGCTGTGAAAGAGTTTGAGGACAAGAAGGTAGAGCTGAAGGAGAACCTGATTGCC
GAGCTCGAGGAGAAGAAGAAGATGATTGAGAATGAGAAGCTCACGATGGAGCTCACCGGAGATT
CTATGGAAGTGAAACCCATCATGACCAGAAAATTACGGAGGCGACCAAACGATCCTGTCCCCAT
TCCAGACAAGAGGAGAAAACCAGCTCCTGCTCAGCTAAACTACTTGTTGACAGACGAGCAGATC
ATGGAAGATCTGAGAACACTGAACAAGCTTAAGTCACCCAAGAGACCAGCCTCCCCATCCTCTC
CTGAACACTTGCCTGCCACACCTGCAGAGTCTCCAGCACAGAGATTTGAGGCGCGGATAGAAGA
TGGCAAACTGTATTATGATAAGAGATGGTACCACAAGAGCCAGGCCATCTACCTGGAGTCTAAG
GACAACCAGAAACTGAGCTGTGTGATCAGCTCAGTAGGAGCCAATGAGATCTGGGTGAGGAAGA
CCAGCGACAGCACCAAGATGCGGATCTACCTGGGCCAGCTGCAGCGCGGGCTCTTCGTGATCCG
CCGGCGAAAATTCTTAACTTACCGGGACTAGCTCCTTGGCCTGGGACATGGAGAGCACTGTGGA
GTCTTCAGGGCGCTCACGTGGCCGCCACCTCCATCTCTGTCCGCTCTGTCCTGCTCCGCCTCTT
CCAGAACTCGGTCACCAGAGACTCTTGCTTTCGGAGTCCGGGGTCACCACCTTCCTTGTATTCC
ACTCTTGTCCTGTTTTGTTTATACTTGATCCTTTTTCCGACCTCCTTGGAGTTTGAAGGGAAGC
TGTTTTTAACAATTATCTCTAGGTCTCTGAAGAGCATCGGGTGTGCTTTCCTGCCTGAATCTGA
TTGGCAGATCGTGTGCCTGCTTCCTACCTTGGGCCCAGAAGCGTGGGGCAGGAGAGTTCTCCTG
ACTCTGCTTTTCTTGGAGAAATAAATGACACAGAACATCTCATCTGCCTTGGGCTGCTACTCCG
CTGACTGGCTTCACTCTGGATACCGCAACCAGCGGACGGGGCTGGGGGAGGGGCGTGGCATGTT
CACCGCAGGCTGGAGTCACCACTGCGAACAGTCTCCAGCAAACACGATTTATTTACACACCCCA
GTCCCTGTTCAGGGTGGAAGAAGTGGCCATTTCAGAAGTTTGTGTCTGTAACTCCTCTCTCTAG
CTCCCAATGGCTGCAAGTATTTATCGTGTGCCCCACTGTGGTGTGGGTTCTCGGTAAGTGGGGT
GGCAGAGTGGGTGCCCCATGTGTGGTCCGTGCCTCACTCCTGAGCTGGACCCACCGTGATGCTG
GGCTGTTCAACACCATGGAACCCCCAACCTCCCCTGAGGTTTGTCCCGTGTCAGTGACAAGGAG
AGCTCTGTCAAAGCTGCAGCCACCACCTCTGTGTGCTGCTTGAGCCCCAGCGAAGCCCCCTGCC
TTGGCCCTCTTGCCCCCTGGGCCGGCCATTGGAGAAAGGACTGGTGCGGCTGGGCAGAGGACTC
CTCACGCTCTAGCTGCCAGCATGCCATGGGAAACGAAGCGGACCAGAGTGCCTATCACCACCTC
TGGGCTATCAGTAGACTGTCCACACCTTGTCTTGCTCTTAGCCCCTCGGACTCCATCCGTGTTG
CCCCCTGGTGTCCCACGGAAGACTGTACAGAACCATTGTTTATTTATAGCCACTCTCCCATTGG
ATTTTTAAGAAAACAGGATAAACGATGATGTTTATGAATTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001418749	(Get FASTA)	NCBI Sequence Viewer
	NP_001418750	(Get FASTA)	NCBI Sequence Viewer
	NP_001418751	(Get FASTA)	NCBI Sequence Viewer
	NP_001418752	(Get FASTA)	NCBI Sequence Viewer
	NP_001418753	(Get FASTA)	NCBI Sequence Viewer
	XP_038946110	(Get FASTA)	NCBI Sequence Viewer
	XP_341093	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM13837	(Get FASTA)	NCBI Sequence Viewer
	EDM13838	(Get FASTA)	NCBI Sequence Viewer
	EDM13839	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000067032
	ENSRNOP00000067032.4
	ENSRNOP00000093128.1

RefSeq Acc Id:

XP_341093 ⟸ XM_341092

- Peptide Label:

isoform X1

- Sequence:

show sequence

MSAAGLLAPAPAPAAAPPAPEYYPEDDEELESVEDDERSCRGRESDEDTEDASETDLAKHDEED
YVEMKEQMYQDKLASLKRQLQQLQEGTLQEYQKRMKKLDQQYRERIRNAELFLQLETEQVERNY
IKEKKAAVKEFEDKKVELKENLIAELEEKKKMIENEKLTMELTGDSMEVKPIMTRKLRRRPNDP
VPIPDKRRKPAPAQLNYLLTDEQIMEDLRTLNKLKSPKRPASPSSPEHLPATPAESPAQRFEAR
IEDGKLYYDKRWYHKSQAIYLESKDNQKLSCVISSVGANEIWVRKTSDSTKMRIYLGQLQRGLF
VIRRRKFLTYRD

hide sequence

Ensembl Acc Id:

ENSRNOP00000067032 ⟸ ENSRNOT00000075646

RefSeq Acc Id:	XP_038946110 ⟸ XM_039090182
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000093128 ⟸ ENSRNOT00000117681

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-M0RBT5-F1-model_v2	AlphaFold	M0RBT5	1-332	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305986	AgrOrtholog
BioCyc Gene	G2FUF-19057	BioCyc
Ensembl Genes	ENSRNOG00000001139	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000075646	ENTREZGENE
	ENSRNOT00000075646.5	UniProtKB/TrEMBL
	ENSRNOT00000117681.2	UniProtKB/TrEMBL
InterPro	Sds3	UniProtKB/TrEMBL
NCBI Gene	360819	ENTREZGENE
PANTHER	PTHR21964	UniProtKB/TrEMBL
Pfam	Sds3	UniProtKB/TrEMBL
PhenoGen	Suds3	PhenoGen
RatGTEx	ENSRNOG00000001139	RatGTEx
SMART	Sds3	UniProtKB/TrEMBL
UniProt	A0A8I6AIA9_RAT	UniProtKB/TrEMBL
	A6J1P8	ENTREZGENE, UniProtKB/TrEMBL
	A6J1Q0	ENTREZGENE, UniProtKB/TrEMBL
	M0RBT5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2025-11-13	Suds3	SIN3A corepressor complex component SDS3	Suds3	SDS3 homolog, SIN3A corepressor complex component	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-10-01	Suds3	SDS3 homolog, SIN3A corepressor complex component	Suds3	suppressor of defective silencing 3 homolog (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Suds3	suppressor of defective silencing 3 homolog (S. cerevisiae)	RGD1305986_predicted	similar to FLJ00052 protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1305986_predicted	similar to FLJ00052 protein (predicted)	LOC360819_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC360819_predicted	similar to FLJ00052 protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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