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Gene: Cux2 (cut-like homeobox 2) Rattus norvegicus

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Symbol:

Cux2

Name:

cut-like homeobox 2

RGD ID:

1305967

Description:

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including positive regulation of nervous system development; regulation of gene expression; and short-term memory. Predicted to act upstream of or within negative regulation of DNA-templated transcription. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 67. Orthologous to human CUX2 (cut like homeobox 2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

cut-like 2; cut-like 2 (Drosophila); Cutl2; homeobox protein cut-like 2; LOC288665

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CUX2 (cut like homeobox 2)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Cux2 (cut-like homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cux2 (cut like homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CUX2 (cut like homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CUX2 (cut like homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cux2 (cut like homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CUX2 (cut like homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CUX2 (cut like homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cux2 (cut like homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Cux2 (cut like homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ALKBH2 (alkB homolog 2, alpha-ketoglutarate dependent dioxygenase)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	CUX2 (cut like homeobox 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Cux2 (cut-like homeobox 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cux2b (cut-like homeobox 2b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	COY1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	ceh-44	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ct	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ct	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cux2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	cone-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	40,168,402 - 40,368,303 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	40,149,292 - 40,366,528 (+)	Ensembl				GRCr8
mRatBN7.2	12	34,507,723 - 34,707,581 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	34,520,959 - 34,705,806 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	35,693,412 - 35,878,823 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	36,304,624 - 36,490,037 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	35,357,113 - 35,542,505 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	40,016,774 - 40,221,067 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	40,018,937 - 40,219,291 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	41,893,143 - 42,092,024 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	35,850,093 - 35,910,414 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	36,188,363 - 36,371,360 (+)	NCBI		Celera
RGSC_v3.1	12	35,727,879 - 35,773,518 (+)	NCBI
Cytogenetic Map	12	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO)

developmental and epileptic encephalopathy (ISO)

developmental and epileptic encephalopathy 67 (ISO)

epilepsy with generalized tonic-clonic seizures (ISO)

genetic disease (ISO)

intellectual disability (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,3',4,4',5-pentachlorobiphenyl (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

8-Br-cAMP (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

amitrole (EXP)

arsane (ISO)

arsenic atom (ISO)

atrazine (EXP,ISO)

azoxystrobin (EXP)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bromobenzene (EXP)

Butylbenzyl phthalate (ISO)

carbon nanotube (ISO)

carmustine (EXP)

chlorpyrifos (EXP)

clobetasol (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

diazinon (ISO)

dibutyl phthalate (ISO)

dichloromethane (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

folic acid (ISO)

fulvestrant (ISO)

genistein (EXP)

gentamycin (EXP)

glyphosate (EXP)

imidacloprid (EXP)

indole-3-methanol (EXP)

iron dichloride (ISO)

isoprenaline (ISO)

isotretinoin (ISO)

lead nitrate (ISO)

lipopolysaccharide (ISO)

methapyrilene (ISO)

methimazole (EXP)

methoxychlor (EXP)

methylmercury chloride (ISO)

morphine (ISO)

N-acetyl-L-cysteine (EXP)

N-ethyl-N-nitrosourea (ISO)

N-methyl-4-phenylpyridinium (EXP,ISO)

N-nitrosodiethylamine (EXP)

nevirapine (EXP)

O-methyleugenol (ISO)

okadaic acid (ISO)

paracetamol (ISO)

pentachlorophenol (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

progesterone (ISO)

quercetin (EXP)

rotenone (EXP,ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

tamoxifen (ISO)

tetrachloromethane (EXP)

thiabendazole (EXP)

thioacetamide (EXP)

titanium dioxide (EXP,ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triphenyl phosphate (EXP)

triptonide (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cognition (ISO)

DNA-templated transcription (IEA)

negative regulation of DNA-templated transcription (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

positive regulation of dendrite morphogenesis (ISO)

positive regulation of dendritic spine morphogenesis (ISO)

positive regulation of excitatory postsynaptic potential (ISO)

positive regulation of gene expression (ISO)

positive regulation of synapse assembly (ISO)

regulation of transcription by RNA polymerase II (IBA)

short-term memory (ISO)

Cellular Component

nucleus (IBA,IEA,ISO)

Molecular Function

DNA binding (IEA,ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

DNA-binding transcription repressor activity, RNA polymerase II-specific (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (ISO)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IBA,ISO)

sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:15389760	PMID:15656993	PMID:17412818	PMID:18794345	PMID:19056867	PMID:20510857	PMID:26221032

Genomics

Comparative Map Data

Cux2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	40,168,402 - 40,368,303 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	40,149,292 - 40,366,528 (+)	Ensembl				GRCr8
mRatBN7.2	12	34,507,723 - 34,707,581 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	34,520,959 - 34,705,806 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	35,693,412 - 35,878,823 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	36,304,624 - 36,490,037 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	35,357,113 - 35,542,505 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	40,016,774 - 40,221,067 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	40,018,937 - 40,219,291 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	41,893,143 - 42,092,024 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	35,850,093 - 35,910,414 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	36,188,363 - 36,371,360 (+)	NCBI		Celera
RGSC_v3.1	12	35,727,879 - 35,773,518 (+)	NCBI
Cytogenetic Map	12	q16	NCBI

CUX2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	111,034,165 - 111,350,554 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	111,033,853 - 111,350,554 (+)	Ensembl			hg38	GRCh38
GRCh37	12	111,471,969 - 111,788,358 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	109,956,212 - 110,272,739 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	109,934,548 - 110,251,076	NCBI
Celera	12	111,098,413 - 111,414,529 (+)	NCBI		Celera
Cytogenetic Map	12	q24.11-q24.12	NCBI
HuRef	12	108,667,813 - 108,803,094 (+)	NCBI		HuRef
CHM1_1	12	111,439,881 - 111,756,318 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	111,013,350 - 111,331,050 (+)	NCBI		T2T-CHM13v2.0

Cux2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	121,996,025 - 122,188,522 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	121,994,429 - 122,188,165 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	121,857,962 - 122,050,415 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	121,856,366 - 122,050,102 (-)	Ensembl			mm10	GRCm38
MGSCv37	5	122,310,225 - 122,497,834 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	122,120,833 - 122,308,442 (-)	NCBI		MGSCv36	mm8
Celera	5	118,950,598 - 119,138,874 (-)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	62.02	NCBI

Cux2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955482	7,955,039 - 8,043,533 (+)	Ensembl
ChiLan1.0	NW_004955482	7,783,483 - 8,045,808 (+)	NCBI	ChiLan1.0	ChiLan1.0

CUX2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	119,094,013 - 119,417,278 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	119,090,421 - 119,465,960 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	108,600,286 - 108,975,588 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	112,143,682 - 112,313,451 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	112,175,555 - 112,311,221 (+)	Ensembl			panPan2	panpan1.1

CUX2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	8,711,816 - 8,997,263 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	8,730,435 - 8,993,205 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	8,874,945 - 9,160,037 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	8,971,508 - 9,256,848 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	8,990,189 - 9,255,070 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	8,928,111 - 9,212,941 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	8,990,069 - 9,275,112 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	8,943,481 - 9,228,574 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Cux2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	155,419,639 - 155,516,332 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936558	3,963,274 - 4,062,181 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936558	3,970,114 - 4,060,326 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CUX2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	32,311,188 - 32,587,203 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	32,311,781 - 32,587,194 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	34,262,426 - 34,582,740 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CUX2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	106,462,877 - 106,602,847 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666037	138,495,924 - 138,814,132 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cux2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624747	20,784,323 - 21,021,090 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Cux2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	31,793,278 - 31,983,606 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Cux2
1228 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	92
Count of miRNA genes:	85
Interacting mature miRNAs:	89
Transcripts:	ENSRNOT00000001697
Prediction methods:	Microtar, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	24805022	52308831	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	11200494	52308831	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	50386405	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	25989355	52308831	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1300162	Bp188	Blood pressure QTL 188	3.19		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	37764145	51558799	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18473041	52308831	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15264248	52308831	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200497	52308831	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	11743528	52308831	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
70169	Eae13	Experimental allergic encephalomyelitis QTL 13		0.032	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	12	29775522	42298555	Rat
1600386	Calcic2	Intracellular calcium level QTL 2		0.001	platelet physiology trait (VT:0005464)	platelet intracellular calcium level (CMO:0000922)	12	33700432	46784661	Rat
1300175	Cm5	Cardiac mass QTL 5	3.78		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	33700432	51558799	Rat
1556747	Calcic1	Intracellular calcium level QTL 1		3.6	platelet calcium amount (VT:0010500)	platelet intracellular calcium level (CMO:0000922)	12	33700432	46784661	Rat
631829	Alc6	Alcohol consumption QTL 6	4.7		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	12	34243475	43352593	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	17464979	46784661	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	16187438	52308831	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	49212240	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	16135029	52308831	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	51213550	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	11200494	52308831	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	11200494	52308831	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	41361854	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18473041	52308831	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2747694	47747694	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	3087180	48087180	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	16135029	52308831	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat

Markers in Region

D12Rat18

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	34,702,426 - 34,702,587 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	40,215,912 - 40,216,072	NCBI	Rnor6.0
Rnor_5.0	12	42,086,869 - 42,087,029	UniSTS	Rnor5.0
RGSC_v3.4	12	35,907,119 - 35,907,279	UniSTS	RGSC3.4
RGSC_v3.4	12	35,907,118 - 35,907,279	RGD	RGSC3.4
Celera	12	36,367,985 - 36,368,141	UniSTS
RGSC_v3.1	12	35,770,507 - 35,770,667	RGD
RH 3.4 Map	12	618.7	RGD
RH 3.4 Map	12	618.7	UniSTS
RH 2.0 Map	12	465.7	RGD
FHH x ACI Map	12	35.52	RGD
Cytogenetic Map	12	q16	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	11	67	163	91	90	59	61	59	6	323	160	11	142	80	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001271380	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001415781	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769216	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769217	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769218	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089246	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089247	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089248	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089249	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089251	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089252	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089253	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089255	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089256	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089257	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089259	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089260	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089261	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089262	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089263	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000001697 ⟹ ENSRNOP00000001697

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	40,181,688 - 40,366,528 (+)	Ensembl
mRatBN7.2 Ensembl	12	34,520,959 - 34,705,806 (+)	Ensembl
Rnor_6.0 Ensembl	12	40,018,937 - 40,219,291 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000132609 ⟹ ENSRNOP00000105858

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	40,324,963 - 40,366,528 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000159839 ⟹ ENSRNOP00000108400

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	40,295,584 - 40,366,528 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000164301 ⟹ ENSRNOP00000100533

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	40,179,165 - 40,366,528 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000172779 ⟹ ENSRNOP00000106645

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	40,152,587 - 40,366,528 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000173895 ⟹ ENSRNOP00000098742

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	40,149,292 - 40,366,528 (+)	Ensembl

RefSeq Acc Id:

NM_001271380 ⟹ NP_001258309

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,181,688 - 40,366,528 (+)	NCBI
mRatBN7.2	12	34,520,959 - 34,705,806 (+)	NCBI
Rnor_6.0	12	40,018,937 - 40,219,291 (+)	NCBI
Rnor_5.0	12	41,893,143 - 42,092,024 (+)	NCBI
Celera	12	36,188,363 - 36,371,360 (+)	NCBI

Sequence:

show sequence

TGACTGTGGAAGCTGCTGCACGGGACCTTCCAGGCCTAGGCTGGTGCAGCTGCCCACTCTCTGC
CCCCGCCTCAGACTCTCCTGTGGTCCCTTGCACAGTGTGCAAAGCCCAGGGTCTTCCAGACATC
CATCCCTCAGCCCTTTGCCAGGGACCCTTTCTGGTACATCCTCTTAGCGACTCCTCTTCCAGAC
TTGATTGCACCTCTTACTCCGTAGAGGAAACTTCTACCCATTGTGCCGTACAGTGGGACTGTTA
GTATTCTCCTACTACACGGAGTACGGCGGTGTTCAGCAGAGCGTGGGGCGTGCGATCATGCCTT
AAGGAGCTTAATTCTGTCGCCTCAGAGCTGTCTGTGCCACAGGAGGAAAGCGAGCATTCTCCTA
AACGTTTAATTGAACTCCGCCGGGAATTTAAGAAAAATGTGCCAGAGGGAATCAGAGCGATGGT
AGCCCCAGTGCTGAAAAGCTTCCAAGCTGAGGTGGTGGCTCTCAGTAAGAGAAGTCAGGAGGCA
GAGGCAGCATTCCTGAGTGTTTATAAGCAATTAATTGAAGCGCCAGACCCTGTCCCGTCGGTTG
AGGTGGCGCGGACTCTAGACGACAGACTGCAGCGTCCCAGCTTCCACCCCAGTGGGCAGCGCCT
ACGAGACGTGCACATCTCGTGGAAGAGGTGCCCAGAGCCACCCAGTGCCAGAGAGCAGAACGAG
GGGACGTGTCCCACCGGGCACACGCCAGCCAACGGTAACCACCTGCCAGGTCCCGAGGACACCC
TCGTGACAGACACCTTGCTGCAGAAGGATGAGGCCGAGAGACAGAAGGGCCTCCAAGAAGTCCA
CGTCACCTTGGCAGCCAGGCTGGGGGAGGCAGAGGAGAAAATCAAGGTGTTACATTCAGCGCTA
AAGGCCACACAGACGGAGCTGCTGGAGCTGAGGAGGAAATACGATGAGGAGGCTGCATCCAAGG
CCGATGAGGTCGGCTTGATCATGACGAACCTGGAGAAGGCCAACCAGCGAGCAGAGGCTGCCCA
GCGGGAGGTAGAAAGCCTCCGGGAGCAGCTGGCATCGGTCAACAGCTCCATTCGCCTGGCTTGC
TGCTCCCCGCAGGGACCCGGTGGGGAGAAGGTGAGCTTCGCCCTGTGCTCAGGGCCCCGGCTGG
AGGCAGCGCTGGCTTCCAAGGACAGGGAGATCCTCAGGCTGCTGAAGGACGCCCAGCAGCTGCG
GCACTCTCTGCAGGAGCTGGAAGAGGTCTCAGCCAACCAAATCGCTGATCTGGAGCGGCAGCTA
GCGGCCAAGTCTGAGGCCATAGAGAAACTCCAAGAAAAGCTGGAGGCCCAGGCTGACTATGAAG
AGATTAAAACAGAGCTGAGCATCCTGAGAGCCATGAAGCTGGCCTCCAGCACGTGCAGCCTCCC
ACAGGCGCTGGGCAAGCCTGACGACCCACTGCTCATGGCCAAGGATGCCTTCTTCCCCACACAG
AAGCTCCTGCTGGAAAAGCCCGCGCTGCTGGCCAGCCCTGAGGAGGACCCCTCGGAGGATGACT
CTATCAAGGGCTCACTGGGCATGGAGCCCTCCTACCCTCCTCAGCTTCCACCTCCGCCAGGCCC
TGAAGACCCGCTGTCCCCAAGCCCTACGCAGCCCCTGCTGGGCCCCAGCCTGGGTCCTGATGGA
CCAAGGACTTTCTCGCTGTCCCCCTTCCCCAGCCTGGCACCGGGGGAGAGGCTGGCTGGGGACC
CACTGCTGTCCAAACATATGATGGCCCCAGTTGCCTTCAAAGGGGAAACGGGCAACCTGCTGGC
ATTCCCACCGGCCTTCTATGGCGGTGCCAAGCCTCCAACGGCTCCTGCCGCCCCAGTGCCCGGC
CCTGAGCCCTCTGGGGCCCCAGAGCCTGTGGACGGGGCTGGGCCAGAGGAGGAGCAGCTGGACA
CGGCCGAGATCGCCTTCCAGGTGAAGGAGCAGCTTCTGAAGCACAACATTGGCCAGCGTGTGTT
TGGCCACTATGTGCTGGGACTGTCGCAGGGCTCGGTGAGTGAGATCCTGGCACGGCCCAAGCCG
TGGCGCAAGCTCACGGTGAAGGGCAAGGAGCCCTTCATCAAGATGAAGCAGTTCCTGTCGGATG
AGCAGAACGTGCTGGCCCTGCGCACCATCCAGGTGAGGCAGCGAGGCAGCATCACCCCGAGAAT
CCGAACTCCTGAGACCGGCTCAGACGACGCCATCAAGAGTATCCTGGAGCAGGCCAAGAAGGAG
ATTGAGTCTCAGAAAGGGGGTGAGTCCAAGAACTCCCCTGCCTCCGTGAGCATCCCCAACGGCA
CAGCTTCCTCCAGCACCTCGGAAGACGCCATCAAGAACATTCTGGAACAAGCCCGCCGCGAAAT
GCAAGCCCAGCAGCAGGCCCTGCTGGAGATGGAGTCGGGTCCCAGGGGCCGCTCAGTGCCTCCC
TCTCCTCCGGAGCGGCCCTCGCCAGCCACTATGAGCCAGAATGGGGCCCTGGCCTGCGTGAAGC
AGGAAGACGGCGGCTGCAGCAGCAGCAGTAGCGGCAGTGCGCAGGCGCCGCTTGCTGTCCTGTC
CCCCGCTGCATTTGTGCAGCGGATCATCCGCAAGGTGAAGTCAGAGATCGGCGACGCTGGCTAC
TTTGATCACCACTGGGCATCAGACCGTGGTCTGCTCAGCCGTCCCTACGCCTCCGTGTCACCTT
CCCTCTCCTCCTCCTCCAGCTACTCGGGACAGCCCAATGGGCGAGCCTGGCCCCGTGGGGACGA
GGCAACCATTGCCCCTGAGGACGAAGCGGCTACGGGCATGGGGGAGGACGAGGCCCCCAGGGTG
GGAGAGCTCAAGGCCGAGGCCGGAGTCTCCGAGGTGGGTGGCGGGCGACTGCCCTACTACCCAG
CGTATGTGCCCCGCACACTCAAGCCCACTGTGCCGCCCCTAACACCCGAGCAATACGAGCTATA
CATGTACCGGGAGGTAGACACTCTGGAGCTCACCCGCCAGGTCAAGGAGAAGCTAGCCAAGAAC
GGCATCTGCCAGCGCATCTTTGGGGAGAAGGTCCTGGGACTGTCTCAGGGCAGCGTGAGTGACA
TGCTGTCACGGCCAAAGCCATGGAGCAAGCTGACACAGAAGGGCCGGGAGCCTTTCATCCGCAT
GCAGTTGTGGCTATCAGACCAGCTGGGCCAGGGCCAGGCCCCAAACCAGCAGCCCAGCGCTAGC
CAGGCCAGCCCCACGGAGCCAACGTCCTCACCATCACCTCCCCCAAGCCCCACGGAGCCTGAAA
AGACTTCCCAGGAGCCTCTGGGCCTGTCCCTAGAAAGCAGCAAGGAGAATCAGCAACCAGAGGG
CCGGGCCAGCTCCACCCTGGGTGGGAAGCCCCTCTCAAGCAGCCAGACTACGGGGGGCATCCAG
GAGATGGTGGCCATGTCCCCAGAGCTGGACACATACTCCATCACCAAGAGAGTCAAGGAGGTCC
TCACGGACAACAACCTAGGGCAGCGGTTGTTTGGTGAGAGCATCCTGGGGCTAACACAGGGCTC
CGTGTCAGACCTGCTGTCGAGGCCCAAGCCCTGGCACAAGCTGAGCTTGAAGGGCCGGGAGCCC
TTTGTGCGCATGCGGCTGTGGCTGAGCGACCCCCACAATGTGGAAAAGCTTCGAGATGTGAAGA
AGCTGGAGAAGAAAGCCTATCTGAAACGCCGATACGGGCTCATCAGCACGGGCTCTGACAGCGA
GTCACCGGCAGCTCACTCCGAGTGTCCCAGCCCATGTCTGCAGCCGCAGGAGTTGAGCCTCATG
CAGGCCAAGAAGCCACGTGTGGTGCTGGCACCGGCCGAGAAGGAGGCTCTGCGGAAGGCCTACC
AGCTAGAGCCCTACCCCTCACAGCAGACCATAGAGTTGCTCTCTTTCCAGCTCAACCTCAAGAC
AAACACTGTCGTCAACTGGTTCCACAACTACAGGTCCAGGATGCGCCGGGAGATGCTGGTGGAG
GGAACACAGGATGACCCAGACTTTGACCCAAGTGGGGGCTCCAGTGTCCTGCCATCAGGCCACA
CCCACACAGACCCCACCCCGCAGAGCCCTGACTCAGAGATTGAGGACCAAAAGCCCCCCATGAA
GAGCCTGGAGCTGCAGGAACCTGAGAGTCCCGTACACCAAGCAGCCCCAGACAGGGCTGTGGTG
AAGATTAAGCAGGAAGAGGGTTTAGAGGTGGATGGGGACAGCCAGCCCCAGGACATAGGGGATC
CAGACAGAGGGCAAGGTGGCCCCAAAGAGGAGGATACTCACCCTCTGGGGAACAATGAACTCTC
AGAGCTGGTCCCCGGGCCTTTCCTTCCAGGCACACCCAATCCAGACTGCTCTTCATTGCACACC
CCCCAAGCAAAAGAGACTGGGGAACAGGTTCACTCAGAGCCTCTGAGTTTCAAGTCCACCTCTG
AATCCTCATGCTGCAGCCTGGAGGGGCCACCGAACTCTCCCTCTGCCATCTCCTCGCCAGACCT
CATGACATGTGTGTCACCCGCCCCTTCCTCCTCAGCCCCCATCTCCCCATCCCTACCTGGCACC
CTACCTGCCAAAGTGCCGAGTACCAGTCCCACTGCTGACCCAGCTGCAGCCTTGCACCCCAGCA
CTAAGGTGAACCCCAACTTGCAGCGGCGGCATGAGAAAATGGCCAACTTGAACAGTATAATCTA
CCGACTGGAGAGGGCTGCCAACCGGGAAGAGGCTCTGGAGTGGGAATTCTGAAGCTGGGGCAAG
GGACATACCCCAGAGGTCACCTTCCCTCCCTCCCTCCTGCCCTCTCCCAGATGCGGTGGGGCCA
GAGAGGCAAGAACTCAGCCATGCAGATGTGGACAACAATGTTAAGCCGTTTACGTTTATTGTTG
TATCACTAGTTACCTGAGGTTGTGTGTGAGCAGATGCTACCGCCTCTTCTTTTTGATAGCCCTG
CTTGTAGGAGGCACTGGAATCCTGCCCTCATCCTCTCCCCTGCGGGAAGGCAGGAGCAAAAAGG
TACCACATTCTCACTCAAAAACTCCAAACTCTTTTAGAAAAATAAAGAAATATTTATAGACCTC
TTTCAGCTATTTTAATAAAGGATCCTTTGGAAATTT

hide sequence

RefSeq Acc Id:

NM_001415781 ⟹ NP_001402710

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,179,282 - 40,366,528 (+)	NCBI
mRatBN7.2	12	34,518,551 - 34,705,806 (+)	NCBI

RefSeq Acc Id:

XM_039089246 ⟹ XP_038945174

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,179,068 - 40,368,303 (+)	NCBI
mRatBN7.2	12	34,518,333 - 34,707,581 (+)	NCBI

RefSeq Acc Id:

XM_039089247 ⟹ XP_038945175

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,179,067 - 40,368,303 (+)	NCBI
mRatBN7.2	12	34,518,333 - 34,707,581 (+)	NCBI

RefSeq Acc Id:

XM_039089248 ⟹ XP_038945176

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,179,068 - 40,368,303 (+)	NCBI
mRatBN7.2	12	34,518,333 - 34,707,581 (+)	NCBI

RefSeq Acc Id:

XM_039089249 ⟹ XP_038945177

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,179,069 - 40,368,303 (+)	NCBI
mRatBN7.2	12	34,518,334 - 34,707,581 (+)	NCBI

RefSeq Acc Id:

XM_039089251 ⟹ XP_038945179

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,295,468 - 40,368,303 (+)	NCBI
mRatBN7.2	12	34,634,880 - 34,707,581 (+)	NCBI

RefSeq Acc Id:

XM_039089252 ⟹ XP_038945180

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,179,361 - 40,368,303 (+)	NCBI
mRatBN7.2	12	34,518,333 - 34,707,581 (+)	NCBI

RefSeq Acc Id:

XM_039089253 ⟹ XP_038945181

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,179,659 - 40,368,303 (+)	NCBI
mRatBN7.2	12	34,518,881 - 34,707,581 (+)	NCBI

RefSeq Acc Id:

XM_039089254 ⟹ XP_038945182

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,168,402 - 40,368,303 (+)	NCBI
mRatBN7.2	12	34,507,723 - 34,707,581 (+)	NCBI

RefSeq Acc Id:

XM_039089255 ⟹ XP_038945183

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,179,361 - 40,368,303 (+)	NCBI
mRatBN7.2	12	34,518,333 - 34,707,581 (+)	NCBI

RefSeq Acc Id:

XM_039089256 ⟹ XP_038945184

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,168,402 - 40,368,303 (+)	NCBI
mRatBN7.2	12	34,507,723 - 34,707,581 (+)	NCBI

RefSeq Acc Id:

XM_039089257 ⟹ XP_038945185

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,168,402 - 40,368,303 (+)	NCBI
mRatBN7.2	12	34,507,723 - 34,707,581 (+)	NCBI

RefSeq Acc Id:

XM_039089259 ⟹ XP_038945187

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,257,235 - 40,368,303 (+)	NCBI
mRatBN7.2	12	34,588,329 - 34,707,581 (+)	NCBI

RefSeq Acc Id:

XM_039089260 ⟹ XP_038945188

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,204,618 - 40,368,303 (+)	NCBI
mRatBN7.2	12	34,543,881 - 34,707,581 (+)	NCBI

RefSeq Acc Id:

XM_039089261 ⟹ XP_038945189

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,179,511 - 40,368,303 (+)	NCBI
mRatBN7.2	12	34,518,779 - 34,707,581 (+)	NCBI

RefSeq Acc Id:

XM_039089262 ⟹ XP_038945190

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,224,283 - 40,368,303 (+)	NCBI
mRatBN7.2	12	34,563,546 - 34,707,581 (+)	NCBI

RefSeq Acc Id:

XM_039089263 ⟹ XP_038945191

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	40,209,056 - 40,368,303 (+)	NCBI
mRatBN7.2	12	34,548,440 - 34,707,581 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001258309	(Get FASTA)	NCBI Sequence Viewer
	NP_001402710	(Get FASTA)	NCBI Sequence Viewer
	XP_038945174	(Get FASTA)	NCBI Sequence Viewer
	XP_038945175	(Get FASTA)	NCBI Sequence Viewer
	XP_038945176	(Get FASTA)	NCBI Sequence Viewer
	XP_038945177	(Get FASTA)	NCBI Sequence Viewer
	XP_038945179	(Get FASTA)	NCBI Sequence Viewer
	XP_038945180	(Get FASTA)	NCBI Sequence Viewer
	XP_038945181	(Get FASTA)	NCBI Sequence Viewer
	XP_038945182	(Get FASTA)	NCBI Sequence Viewer
	XP_038945183	(Get FASTA)	NCBI Sequence Viewer
	XP_038945184	(Get FASTA)	NCBI Sequence Viewer
	XP_038945185	(Get FASTA)	NCBI Sequence Viewer
	XP_038945187	(Get FASTA)	NCBI Sequence Viewer
	XP_038945188	(Get FASTA)	NCBI Sequence Viewer
	XP_038945189	(Get FASTA)	NCBI Sequence Viewer
	XP_038945190	(Get FASTA)	NCBI Sequence Viewer
	XP_038945191	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM13712	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000001697
	ENSRNOP00000001697.8
	ENSRNOP00000098742.1
	ENSRNOP00000100533
	ENSRNOP00000100533.1
	ENSRNOP00000105858.1
	ENSRNOP00000106645.1
	ENSRNOP00000108400.1

RefSeq Acc Id:	NP_001258309 ⟸ NM_001271380
- Peptide Label:	isoform 1
- UniProtKB:	F1M048 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVAPVLKSFQAEVVALSKRSQEAEAAFLSVYKQLIEAPDPVPSVEVARTLDDRLQRPSFHPSGQ RLRDVHISWKRCPEPPSAREQNEGTCPTGHTPANGNHLPGPEDTLVTDTLLQKDEAERQKGLQE VHVTLAARLGEAEEKIKVLHSALKATQTELLELRRKYDEEAASKADEVGLIMTNLEKANQRAEA AQREVESLREQLASVNSSIRLACCSPQGPGGEKVSFALCSGPRLEAALASKDREILRLLKDAQQ LRHSLQELEEVSANQIADLERQLAAKSEAIEKLQEKLEAQADYEEIKTELSILRAMKLASSTCS LPQALGKPDDPLLMAKDAFFPTQKLLLEKPALLASPEEDPSEDDSIKGSLGMEPSYPPQLPPPP GPEDPLSPSPTQPLLGPSLGPDGPRTFSLSPFPSLAPGERLAGDPLLSKHMMAPVAFKGETGNL LAFPPAFYGGAKPPTAPAAPVPGPEPSGAPEPVDGAGPEEEQLDTAEIAFQVKEQLLKHNIGQR VFGHYVLGLSQGSVSEILARPKPWRKLTVKGKEPFIKMKQFLSDEQNVLALRTIQVRQRGSITP RIRTPETGSDDAIKSILEQAKKEIESQKGGESKNSPASVSIPNGTASSSTSEDAIKNILEQARR EMQAQQQALLEMESGPRGRSVPPSPPERPSPATMSQNGALACVKQEDGGCSSSSSGSAQAPLAV LSPAAFVQRIIRKVKSEIGDAGYFDHHWASDRGLLSRPYASVSPSLSSSSSYSGQPNGRAWPRG DEATIAPEDEAATGMGEDEAPRVGELKAEAGVSEVGGGRLPYYPAYVPRTLKPTVPPLTPEQYE LYMYREVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFI RMQLWLSDQLGQGQAPNQQPSASQASPTEPTSSPSPPPSPTEPEKTSQEPLGLSLESSKENQQP EGRASSTLGGKPLSSSQTTGGIQEMVAMSPELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQ GSVSDLLSRPKPWHKLSLKGREPFVRMRLWLSDPHNVEKLRDVKKLEKKAYLKRRYGLISTGSD SESPAAHSECPSPCLQPQELSLMQAKKPRVVLAPAEKEALRKAYQLEPYPSQQTIELLSFQLNL KTNTVVNWFHNYRSRMRREMLVEGTQDDPDFDPSGGSSVLPSGHTHTDPTPQSPDSEIEDQKPP MKSLELQEPESPVHQAAPDRAVVKIKQEEGLEVDGDSQPQDIGDPDRGQGGPKEEDTHPLGNNE LSELVPGPFLPGTPNPDCSSLHTPQAKETGEQVHSEPLSFKSTSESSCCSLEGPPNSPSAISSP DLMTCVSPAPSSSAPISPSLPGTLPAKVPSTSPTADPAAALHPSTKVNPNLQRRHEKMANLNSI IYRLERAANREEALEWEF hide sequence

Ensembl Acc Id:

ENSRNOP00000001697 ⟸ ENSRNOT00000001697

RefSeq Acc Id:	XP_038945182 ⟸ XM_039089254
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038945184 ⟸ XM_039089256
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038945185 ⟸ XM_039089257
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038945180 ⟸ XM_039089252
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038945183 ⟸ XM_039089255
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038945174 ⟸ XM_039089246
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038945176 ⟸ XM_039089248
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038945175 ⟸ XM_039089247
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038945177 ⟸ XM_039089249
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038945189 ⟸ XM_039089261
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038945181 ⟸ XM_039089253
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038945188 ⟸ XM_039089260
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038945191 ⟸ XM_039089263
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038945190 ⟸ XM_039089262
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038945187 ⟸ XM_039089259
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038945179 ⟸ XM_039089251
- Peptide Label:	isoform X5

RefSeq Acc Id:	NP_001402710 ⟸ NM_001415781
- Peptide Label:	isoform 2

Ensembl Acc Id:

ENSRNOP00000098742 ⟸ ENSRNOT00000173895

Ensembl Acc Id:

ENSRNOP00000108400 ⟸ ENSRNOT00000159839

Ensembl Acc Id:

ENSRNOP00000100533 ⟸ ENSRNOT00000164301

Ensembl Acc Id:

ENSRNOP00000106645 ⟸ ENSRNOT00000172779

Ensembl Acc Id:

ENSRNOP00000105858 ⟸ ENSRNOT00000132609

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M048-F1-model_v2	AlphaFold	F1M048	1-1426	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305967	AgrOrtholog
BioCyc Gene	G2FUF-19225	BioCyc
Ensembl Genes	ENSRNOG00000001259	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000001697	ENTREZGENE
	ENSRNOT00000001697.9	UniProtKB/TrEMBL
	ENSRNOT00000132609.1	UniProtKB/TrEMBL
	ENSRNOT00000159839.1	UniProtKB/TrEMBL
	ENSRNOT00000164301	ENTREZGENE
	ENSRNOT00000164301.1	UniProtKB/TrEMBL
	ENSRNOT00000172779.1	UniProtKB/TrEMBL
	ENSRNOT00000173895.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.260.40	UniProtKB/TrEMBL
	Homeodomain-like	UniProtKB/TrEMBL
InterPro	Cux_N	UniProtKB/TrEMBL
	Hmoeo_CUT	UniProtKB/TrEMBL
	Homeobox	UniProtKB/TrEMBL
	Homeodomain-like	UniProtKB/TrEMBL
	Lambda_DNA-bd	UniProtKB/TrEMBL
KEGG Report	rno:288665	UniProtKB/TrEMBL
NCBI Gene	288665	ENTREZGENE
PANTHER	CCAAT DISPLACEMENT PROTEIN-RELATED	UniProtKB/TrEMBL
	HOMEOBOX PROTEIN CUT-LIKE 2	UniProtKB/TrEMBL
Pfam	CUT	UniProtKB/TrEMBL
	CUX1_N	UniProtKB/TrEMBL
	Homeobox	UniProtKB/TrEMBL
PhenoGen	Cux2	PhenoGen
PROSITE	CUT	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000001259	RatGTEx
SMART	CUT	UniProtKB/TrEMBL
	HOX	UniProtKB/TrEMBL
Superfamily-SCOP	Homeodomain_like	UniProtKB/TrEMBL
	Lambda_like_DNA	UniProtKB/TrEMBL
UniProt	A0ABK0KWU3_RAT	UniProtKB/TrEMBL
	A0ABK0LCG7_RAT	UniProtKB/TrEMBL
	A0ABK0LCK9_RAT	UniProtKB/TrEMBL
	A0ABK0LLU9_RAT	UniProtKB/TrEMBL
	A0ABK0LPX3_RAT	UniProtKB/TrEMBL
	F1M048	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-05-24	Cux2	cut-like homeobox 2	LOC687661	similar to cut-like 2	Data merged from RGD:1583046	1643240	APPROVED
2008-03-10	Cux2	cut-like homeobox 2	Cutl2_predicted	cut-like 2 (Drosophila) (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-19	LOC687661	similar to cut-like 2			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-01-12	Cutl2_predicted	cut-like 2 (Drosophila) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM