Rpl10l (ribosomal protein L10 like) - Rat Genome Database

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Gene: Rpl10l (ribosomal protein L10 like) Rattus norvegicus
Analyze
Symbol: Rpl10l
Name: ribosomal protein L10 like
RGD ID: 1305913
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in several processes, including male meiosis I; ribosomal large subunit assembly; and spermatogenesis. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in spermatogenic failure 63. Orthologous to human RPL10L (ribosomal protein L10 like); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-Tetrachlorodibenzofuran; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 60S ribosomal protein L10-like; LOC299106; ribosomal protein L10 like 1; ribosomal protein L10-like; Rpl10l1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8690,280,962 - 90,281,982 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl690,081,656 - 90,287,434 (-)EnsemblGRCr8
mRatBN7.2684,544,771 - 84,545,791 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl684,543,540 - 84,545,816 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx684,906,496 - 84,907,516 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0685,205,875 - 85,206,895 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0684,646,915 - 84,647,935 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0688,231,273 - 88,232,549 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl688,231,611 - 88,232,252 (-)Ensemblrn6Rnor6.0
Rnor_5.0697,714,374 - 97,715,479 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4687,930,206 - 87,930,850 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera683,085,786 - 83,087,061 (-)NCBICelera
RGSC_v3.1687,933,655 - 87,934,326 (-)NCBI
Cytogenetic Map6q24NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12490704   PMID:19946888   PMID:21630459   PMID:23500592  


Genomics

Comparative Map Data
Rpl10l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8690,280,962 - 90,281,982 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl690,081,656 - 90,287,434 (-)EnsemblGRCr8
mRatBN7.2684,544,771 - 84,545,791 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl684,543,540 - 84,545,816 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx684,906,496 - 84,907,516 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0685,205,875 - 85,206,895 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0684,646,915 - 84,647,935 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0688,231,273 - 88,232,549 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl688,231,611 - 88,232,252 (-)Ensemblrn6Rnor6.0
Rnor_5.0697,714,374 - 97,715,479 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4687,930,206 - 87,930,850 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera683,085,786 - 83,087,061 (-)NCBICelera
RGSC_v3.1687,933,655 - 87,934,326 (-)NCBI
Cytogenetic Map6q24NCBI
RPL10L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381446,651,010 - 46,651,781 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1446,651,010 - 46,651,781 (-)Ensemblhg38GRCh38
GRCh371447,120,213 - 47,120,984 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361446,189,966 - 46,190,778 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341446,189,971 - 46,190,778NCBI
Celera1426,980,729 - 26,981,541 (-)NCBICelera
Cytogenetic Map14q21.2NCBI
HuRef1427,238,030 - 27,238,842 (-)NCBIHuRef
CHM1_11447,059,057 - 47,059,869 (-)NCBICHM1_1
T2T-CHM13v2.01440,849,826 - 40,850,597 (-)NCBIT2T-CHM13v2.0
Rpl10l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391266,330,153 - 66,331,175 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1266,330,153 - 66,331,175 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381266,283,379 - 66,284,401 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1266,283,379 - 66,284,401 (-)Ensemblmm10GRCm38
MGSCv371267,384,366 - 67,385,388 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361267,201,984 - 67,203,006 (-)NCBIMGSCv36mm8
Celera1267,414,601 - 67,415,626 (-)NCBICelera
Cytogenetic Map12C2NCBI
cM Map1227.44NCBI
Rpl10l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540915,612,198 - 15,612,842 (+)Ensembl
ChiLan1.0NW_00495540915,612,118 - 15,613,056 (+)NCBIChiLan1.0ChiLan1.0
RPL10L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21547,796,895 - 47,799,297 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11447,013,404 - 47,015,806 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01427,254,150 - 27,255,381 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11445,564,997 - 45,565,806 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1445,565,079 - 45,565,723 (-)EnsemblpanPan2panpan1.1
RPL10L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1823,671,961 - 23,673,085 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl823,672,388 - 23,673,032 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha823,490,753 - 23,491,877 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0823,839,122 - 23,840,246 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl823,839,549 - 23,840,193 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1823,497,887 - 23,499,011 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0823,566,395 - 23,567,518 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0823,895,275 - 23,896,399 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rpl10l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864055,712,572 - 55,713,407 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365832,975,604 - 2,976,248 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365832,975,604 - 2,976,248 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPL10L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1176,603,248 - 176,603,892 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11176,603,177 - 176,604,116 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21196,774,230 - 196,775,074 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RPL10L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12423,667,440 - 23,669,041 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2423,668,304 - 23,668,948 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605312,054,368 - 12,055,219 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rpl10l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473121,941,818 - 21,942,462 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473121,941,646 - 21,944,165 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Rpl10l
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1780,037,169 - 80,038,249 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rpl10l
11 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:103
Count of miRNA genes:88
Interacting mature miRNAs:90
Transcripts:ENSRNOT00000047597
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)66345744194939581Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)64604735391047353Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)66303731995934232Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)686494122112380234Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)66345744194939581Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 12 67 164 91 90 59 85 59 6 339 185 11 143 78 91 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000047597   ⟹   ENSRNOP00000040966
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl688,231,611 - 88,232,252 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117730   ⟹   ENSRNOP00000080665
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl684,543,540 - 84,545,816 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000156121   ⟹   ENSRNOP00000102217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl690,081,656 - 90,282,256 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000165767   ⟹   ENSRNOP00000111206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl690,259,949 - 90,287,434 (-)Ensembl
RefSeq Acc Id: NM_001399664   ⟹   NP_001386593
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8690,280,962 - 90,281,982 (-)NCBI
mRatBN7.2684,544,771 - 84,545,791 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001386593 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000102217
  ENSRNOP00000102217.1
  ENSRNOP00000111206.1
Ensembl Acc Id: ENSRNOP00000040966   ⟸   ENSRNOT00000047597
Ensembl Acc Id: ENSRNOP00000080665   ⟸   ENSRNOT00000117730
RefSeq Acc Id: NP_001386593   ⟸   NM_001399664
- UniProtKB: A0A8I6G4V0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000111206   ⟸   ENSRNOT00000165767
Ensembl Acc Id: ENSRNOP00000102217   ⟸   ENSRNOT00000156121

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A1P2-F1-model_v2 AlphaFold D4A1P2 1-214 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694635
Promoter ID:EPDNEW_R5153
Type:initiation region
Name:Rpl10l_1
Description:ribosomal protein L10-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0688,232,301 - 88,232,361EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305913 AgrOrtholog
BioCyc Gene G2FUF-37297 BioCyc
Ensembl Genes ENSRNOG00000032720 Ensembl
  ENSRNOG00000067139 Ensembl
  ENSRNOG00000086327 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000156121 ENTREZGENE
  ENSRNOT00000156121.1 UniProtKB/TrEMBL
  ENSRNOT00000165767.1 UniProtKB/TrEMBL
NCBI Gene 299106 ENTREZGENE
PhenoGen Rpl10l PhenoGen
RatGTEx ENSRNOG00000032720 RatGTEx
  ENSRNOG00000067139 RatGTEx
  ENSRNOG00000086327 RatGTEx
UniProt A0A8I6G4V0 ENTREZGENE
  A0ABK0LZP7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-04-11 Rpl10l  ribosomal protein L10 like  Rpl10l1  ribosomal protein L10 like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-03-13 Rpl10l1  ribosomal protein L10 like 1  Rpl10l  ribosomal protein L10-like  Name and Symbol changed 629549 APPROVED
2022-06-02 Rpl10l  ribosomal protein L10-like  Rpl10l  ribosomal protein L10-like  Data merged from RGD:149736314 737654 PROVISIONAL
2021-08-09 Rpl10l  ribosomal protein L10-like      Symbol and Name status set to provisional 45752 PROVISIONAL
2008-04-30 Rpl10l  ribosomal protein L10-like   Rpl10l_predicted  ribosomal protein L10-like (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Rpl10l_predicted  ribosomal protein L10-like (predicted)      Symbol and Name status set to approved 70820 APPROVED