Bend7 (BEN domain containing 7) - Rat Genome Database

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Gene: Bend7 (BEN domain containing 7) Rattus norvegicus
Analyze
Symbol: Bend7
Name: BEN domain containing 7
RGD ID: 1305898
Description: Predicted to enable DNA binding activity. Orthologous to human BEND7 (BEN domain containing 7); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BEN domain-containing protein 7; LOC361275; RGD1305898; similar to hypothetical protein FLJ40283
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81778,392,489 - 78,475,459 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1778,393,601 - 78,475,223 (-)EnsemblGRCr8
mRatBN7.21773,483,212 - 73,566,221 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1773,485,282 - 73,567,559 (-)EnsemblmRatBN7.2
Rnor_6.01777,448,430 - 77,527,888 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1777,448,430 - 77,527,894 (-)Ensemblrn6Rnor6.0
Rnor_5.01779,104,805 - 79,183,741 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41784,594,813 - 84,676,430 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1772,922,685 - 73,000,345 (-)NCBICelera
RGSC_v3.11784,603,366 - 84,684,165 (-)NCBI
Cytogenetic Map17q12.3NCBI
JBrowse:




References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19056867  


Genomics

Comparative Map Data
Bend7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81778,392,489 - 78,475,459 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1778,393,601 - 78,475,223 (-)EnsemblGRCr8
mRatBN7.21773,483,212 - 73,566,221 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1773,485,282 - 73,567,559 (-)EnsemblmRatBN7.2
Rnor_6.01777,448,430 - 77,527,888 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1777,448,430 - 77,527,894 (-)Ensemblrn6Rnor6.0
Rnor_5.01779,104,805 - 79,183,741 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41784,594,813 - 84,676,430 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1772,922,685 - 73,000,345 (-)NCBICelera
RGSC_v3.11784,603,366 - 84,684,165 (-)NCBI
Cytogenetic Map17q12.3NCBI
BEND7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381013,438,481 - 13,529,634 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1013,438,484 - 13,529,237 (-)Ensemblhg38GRCh38
GRCh371013,480,481 - 13,571,014 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361013,520,490 - 13,584,982 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341013,520,642 - 13,584,982NCBI
Celera1013,407,599 - 13,472,089 (-)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1013,392,758 - 13,457,254 (-)NCBIHuRef
CHM1_11013,481,474 - 13,545,968 (-)NCBICHM1_1
T2T-CHM13v2.01013,451,518 - 13,542,675 (-)NCBIT2T-CHM13v2.0
Bend7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3924,722,593 - 4,807,035 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl24,722,642 - 4,806,953 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3824,717,787 - 4,802,224 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl24,717,831 - 4,802,142 (+)Ensemblmm10GRCm38
MGSCv3724,638,877 - 4,723,192 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3624,635,417 - 4,718,197 (+)NCBIMGSCv36mm8
Celera24,670,314 - 4,756,739 (+)NCBICelera
Cytogenetic Map2A1NCBI
cM Map22.88NCBI
Bend7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542920,674,392 - 20,754,634 (+)Ensembl
ChiLan1.0NW_00495542920,674,390 - 20,756,760 (+)NCBIChiLan1.0ChiLan1.0
BEND7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2825,954,361 - 26,048,373 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11025,964,117 - 26,053,702 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01013,436,937 - 13,526,652 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11013,769,617 - 13,856,204 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1013,770,301 - 13,830,274 (-)EnsemblpanPan2panpan1.1
BEND7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1222,975,673 - 23,057,029 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl222,977,139 - 23,054,867 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha220,033,792 - 20,114,998 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0223,280,939 - 23,362,298 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl223,280,917 - 23,370,837 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1220,480,803 - 20,562,101 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0221,315,528 - 21,396,970 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0221,943,938 - 22,025,255 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Bend7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093445,637,492 - 5,769,644 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936613239,560 - 318,424 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936613237,498 - 318,480 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BEND7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1048,177,762 - 48,262,051 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11048,177,594 - 48,264,083 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
BEND7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1913,468,831 - 13,549,822 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl913,466,815 - 13,549,715 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605119,003,420 - 19,084,375 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bend7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248051,686,099 - 1,765,766 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248051,685,004 - 1,792,413 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Bend7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11411,064,178 - 11,145,685 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Bend7
733 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:26
Count of miRNA genes:25
Interacting mature miRNAs:25
Transcripts:ENSRNOT00000032173
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172413612784432719Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)177061350286062352Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174238816487388164Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175819406487388164Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)173803135483031354Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)175482950393515804Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174096801789341781Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172723344583975845Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)173803135483031354Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172439059584432719Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)176515487293515804Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)173803135483031354Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173803135483031354Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)174238816487388164Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175560459793006569Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)174265489587654895Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)173768787782687877Rat
1300131Bp193Blood pressure QTL 1933.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176855004093515804Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176369714782818564Rat
1300129Rf25Renal function QTL 253.03blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)174106235286062352Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173219953486201342Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172413612784432719Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2413612784432719Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172413612784432719Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173604553781045537Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)176456982086954580Rat

Markers in Region
BI288939  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21773,484,903 - 73,485,035 (+)MAPPERmRatBN7.2
Rnor_6.01777,448,052 - 77,448,183NCBIRnor6.0
Rnor_5.01779,104,427 - 79,104,558UniSTSRnor5.0
RGSC_v3.41784,594,435 - 84,594,566UniSTSRGSC3.4
Celera1772,922,307 - 72,922,438UniSTS
RH 3.4 Map17729.6UniSTS
Cytogenetic Map17q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 154 89 88 57 62 57 6 324 162 11 133 81 92 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000032173   ⟹   ENSRNOP00000029919
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1778,397,395 - 78,475,223 (-)Ensembl
mRatBN7.2 Ensembl1773,485,282 - 73,567,559 (-)Ensembl
Rnor_6.0 Ensembl1777,448,430 - 77,527,894 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000126225   ⟹   ENSRNOP00000110711
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1778,393,601 - 78,475,223 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000133058   ⟹   ENSRNOP00000104320
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1778,406,692 - 78,475,223 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000143101   ⟹   ENSRNOP00000102919
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1778,393,601 - 78,475,223 (-)Ensembl
RefSeq Acc Id: XM_039096481   ⟹   XP_038952409
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,392,489 - 78,475,439 (-)NCBI
mRatBN7.21773,483,212 - 73,566,206 (-)NCBI
RefSeq Acc Id: XM_039096482   ⟹   XP_038952410
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,392,489 - 78,475,451 (-)NCBI
mRatBN7.21773,483,212 - 73,566,206 (-)NCBI
RefSeq Acc Id: XM_039096483   ⟹   XP_038952411
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,392,489 - 78,475,459 (-)NCBI
mRatBN7.21773,483,212 - 73,566,211 (-)NCBI
RefSeq Acc Id: XM_039096484   ⟹   XP_038952412
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,392,489 - 78,474,926 (-)NCBI
mRatBN7.21773,483,212 - 73,565,565 (-)NCBI
RefSeq Acc Id: XM_039096487   ⟹   XP_038952415
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,432,096 - 78,475,431 (-)NCBI
mRatBN7.21773,526,580 - 73,566,220 (-)NCBI
Ensembl Acc Id: ENSRNOP00000029919   ⟸   ENSRNOT00000032173
RefSeq Acc Id: XP_038952411   ⟸   XM_039096483
- Peptide Label: isoform X3
- UniProtKB: A6JM00 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952410   ⟸   XM_039096482
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038952409   ⟸   XM_039096481
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038952412   ⟸   XM_039096484
- Peptide Label: isoform X5
- UniProtKB: A6JM00 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952415   ⟸   XM_039096487
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000110711   ⟸   ENSRNOT00000126225
Ensembl Acc Id: ENSRNOP00000104320   ⟸   ENSRNOT00000133058
Ensembl Acc Id: ENSRNOP00000102919   ⟸   ENSRNOT00000143101
Protein Domains
BEN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M8D4-F1-model_v2 AlphaFold F1M8D4 1-416 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305898 AgrOrtholog
BioCyc Gene G2FUF-8682 BioCyc
Ensembl Genes ENSRNOG00000022712 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032173.7 UniProtKB/TrEMBL
  ENSRNOT00000126225 ENTREZGENE
  ENSRNOT00000126225.1 UniProtKB/TrEMBL
  ENSRNOT00000133058.1 UniProtKB/TrEMBL
  ENSRNOT00000143101 ENTREZGENE
  ENSRNOT00000143101.1 UniProtKB/TrEMBL
Gene3D-CATH BEN domain UniProtKB/TrEMBL
InterPro BEN_domain UniProtKB/TrEMBL
  BEN_domain_protein_7 UniProtKB/TrEMBL
NCBI Gene 361275 ENTREZGENE
PANTHER BEN DOMAIN-CONTAINING PROTEIN 7 UniProtKB/TrEMBL
  BEN DOMAIN-CONTAINING PROTEIN 7 UniProtKB/TrEMBL
Pfam BEN UniProtKB/TrEMBL
PhenoGen Bend7 PhenoGen
PROSITE BEN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000022712 RatGTEx
SMART BEN UniProtKB/TrEMBL
UniProt A0ABK0L479_RAT UniProtKB/TrEMBL
  A0ABK0LBS2_RAT UniProtKB/TrEMBL
  A0ABK0LY84_RAT UniProtKB/TrEMBL
  A6JM00 ENTREZGENE, UniProtKB/TrEMBL
  F1M8D4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-11-14 Bend7  BEN domain containing 7  RGD1305898  similar to hypothetical protein FLJ40283   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1305898  similar to hypothetical protein FLJ40283   RGD1305898_predicted  similar to hypothetical protein FLJ40283 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1305898_predicted  similar to hypothetical protein FLJ40283 (predicted)  LOC361275_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC361275_predicted  similar to hypothetical protein FLJ40283 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL