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Gene: Pwwp2a (PWWP domain containing 2A) Rattus norvegicus

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Symbol:

Pwwp2a

Name:

PWWP domain containing 2A

RGD ID:

1305891

Description:

Predicted to enable several functions, including NuRD complex binding activity; histone H3K36me3 reader activity; and histone binding activity. Predicted to be involved in chromatin remodeling; positive regulation of transcription elongation by RNA polymerase II; and regulation of transcriptional start site selection at RNA polymerase II promoter. Predicted to be active in nucleus. Orthologous to human PWWP2A (PWWP domain containing 2A); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC303060; PWWP domain-containing protein 2A; RGD1305891; similar to DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA); similar to PWWP domain containing 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PWWP2A (PWWP domain containing 2A)	HGNC	Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Pwwp2a (PWWP domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pwwp2a (PWWP domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PWWP2A (PWWP domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PWWP2A (PWWP domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pwwp2a (PWWP domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PWWP2A (PWWP domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PWWP2A (PWWP domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pwwp2a (PWWP domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Pwwp2a (PWWP domain containing 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Pwwp2a (PWWP domain containing 2A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PWWP2A (PWWP domain containing 2A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pwwp2a (PWWP domain containing 2A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pwwp2a (PWWP domain containing 2A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	pwwp2a	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	pwwp2a	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	28,654,272 - 28,696,693 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	28,656,994 - 28,696,693 (+)	Ensembl				GRCr8
mRatBN7.2	10	28,155,509 - 28,195,255 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	28,155,605 - 28,194,308 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	32,915,090 - 32,953,781 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	1,453,464 - 1,492,155 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	27,885,634 - 27,924,324 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	29,288,060 - 29,335,425 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	29,289,203 - 29,334,478 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	29,128,931 - 29,175,653 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	28,789,156 - 28,828,007 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	27,646,254 - 27,683,715 (+)	NCBI		Celera
RGSC_v3.1	10	28,813,480 - 28,815,082 (+)	NCBI
Cytogenetic Map	10	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

C60 fullerene (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

chloroprene (EXP)

chlorpyrifos (ISO)

crotonaldehyde (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

dexamethasone (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

formaldehyde (ISO)

FR900359 (ISO)

indometacin (ISO)

methimazole (EXP)

methyl methanesulfonate (ISO)

phenethyl isothiocyanate (EXP)

phenobarbital (ISO)

phenylmercury acetate (ISO)

SB 431542 (ISO)

sulfadimethoxine (EXP)

trichostatin A (ISO)

triptonide (ISO)

troglitazone (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chromatin remodeling (IEA,ISO)

positive regulation of transcription elongation by RNA polymerase II (IEA,ISO)

regulation of transcriptional start site selection at RNA polymerase II promoter (IEA,ISO)

Cellular Component

nucleoplasm (IEA,ISO)

nucleus (IBA,IEA,ISO)

Molecular Function

chromatin binding (IBA,IEA,ISO)

histone binding (IBA,IEA,ISO)

histone H3K36me3 reader activity (IEA,ISO)

NuRD complex binding (IEA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:28645917	PMID:37672715

Genomics

Comparative Map Data

Pwwp2a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	28,654,272 - 28,696,693 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	28,656,994 - 28,696,693 (+)	Ensembl				GRCr8
mRatBN7.2	10	28,155,509 - 28,195,255 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	28,155,605 - 28,194,308 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	32,915,090 - 32,953,781 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	1,453,464 - 1,492,155 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	27,885,634 - 27,924,324 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	29,288,060 - 29,335,425 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	29,289,203 - 29,334,478 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	29,128,931 - 29,175,653 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	28,789,156 - 28,828,007 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	27,646,254 - 27,683,715 (+)	NCBI		Celera
RGSC_v3.1	10	28,813,480 - 28,815,082 (+)	NCBI
Cytogenetic Map	10	q21	NCBI

PWWP2A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	160,044,316 - 160,119,450 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	160,061,801 - 160,119,478 (-)	Ensembl			hg38	GRCh38
GRCh37	5	159,502,889 - 159,546,457 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	159,435,467 - 159,479,030 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	5	155,534,450 - 155,578,003 (-)	NCBI		Celera
Cytogenetic Map	5	q33.3	NCBI
HuRef	5	154,597,226 - 154,640,986 (-)	NCBI		HuRef
CHM1_1	5	158,935,909 - 158,979,466 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	160,572,113 - 160,648,036 (-)	NCBI		T2T-CHM13v2.0

Pwwp2a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	43,566,881 - 43,613,248 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	43,572,825 - 43,612,318 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	43,681,125 - 43,722,633 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	43,681,998 - 43,721,491 (+)	Ensembl			mm10	GRCm38
MGSCv37	11	43,495,500 - 43,536,135 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	43,525,378 - 43,566,056 (+)	NCBI		MGSCv36	mm8
Celera	11	48,308,136 - 48,348,710 (+)	NCBI		Celera
Cytogenetic Map	11	B1.1	NCBI
cM Map	11	25.81	NCBI

Pwwp2a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	14,025,964 - 14,051,149 (-)	Ensembl
ChiLan1.0	NW_004955408	14,007,982 - 14,051,149 (-)	NCBI	ChiLan1.0	ChiLan1.0

PWWP2A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	155,247,172 - 155,304,599 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	153,386,720 - 153,443,973 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	155,452,698 - 155,509,961 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	162,083,726 - 162,126,580 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	162,085,988 - 162,130,604 (-)	Ensembl			panPan2	panpan1.1

PWWP2A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	50,558,972 - 50,596,546 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	50,453,374 - 50,490,652 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	50,994,006 - 51,031,276 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	50,993,644 - 51,031,271 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	50,802,291 - 50,839,748 (+)	NCBI		UMICH_Zoey_3.1
UU_Cfam_GSD_1.0	4	51,446,156 - 51,483,420 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Pwwp2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	104,949,993 - 104,986,924 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936515	3,398,938 - 3,434,021 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936515	3,399,339 - 3,436,003 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PWWP2A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	63,409,932 - 63,448,871 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	16	63,409,898 - 63,449,997 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	68,901,249 - 68,940,242 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PWWP2A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	62,428,936 - 62,490,904 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	62,460,139 - 62,490,803 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666034	15,116,595 - 15,181,271 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pwwp2a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	29,404,778 - 29,441,414 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624733	29,404,918 - 29,443,674 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pwwp2a
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	26,524,196 - 26,563,706 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pwwp2a
302 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	197
Count of miRNA genes:	125
Interacting mature miRNAs:	166
Transcripts:	ENSRNOT00000067013
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631564	Apr3	Acute phase response QTL 3	3.9		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	10	15776754	60776754	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	27023535	98502431	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22931373	91127454	Rat
2293669	Bmd33	Bone mineral density QTL 33	4.5	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	10	27443787	72443787	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6660923	73950353	Rat
2313066	Bss63	Bone structure and strength QTL 63	1.4	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	10	5893811	50893811	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1250554	64349221	Rat
2313064	Bmd71	Bone mineral density QTL 71	0.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	10	5893811	50893811	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2293679	Bmd30	Bone mineral density QTL 30	3.5	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	27443787	72443787	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	14653541	59653541	Rat
1354587	Kidm21	Kidney mass QTL 21	3.3		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	10	15533012	73695498	Rat
634329	Pia15	Pristane induced arthritis QTL 15	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	24662123	73695339	Rat
1578761	Stresp21	Stress response QTL 21	3.3		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	6877142	51877142	Rat
70224	Eae3	Experimental allergic encephalomyelitis QTL 3	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	10	27023535	61843633	Rat
2293680	Bss40	Bone structure and strength QTL 40	5.66	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	10	1	35730538	Rat
7387235	Uae41	Urinary albumin excretion QTL 41	5.26	0.1874	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	10	1	30004247	Rat
2298544	Neuinf9	Neuroinflammation QTL 9	4.6		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	10	19939207	64939207	Rat
61332	Eau3	Experimental allergic uveoretinitis QTL 3		0.004	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	18035782	63035782	Rat
10401803	Kidm50	Kidney mass QTL 50			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	10	922197	45922197	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	2103708	47103708	Rat
2313081	Bss64	Bone structure and strength QTL 64	1.3	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	10	5893811	50893811	Rat
2298495	Eae23	Experimental allergic encephalomyelitis QTL 23	16.93		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis duration (CMO:0001424)	10	16175525	61175525	Rat
1598852	Anxrr19	Anxiety related response QTL 19	5.07		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	10	18668419	63668419	Rat
2313087	Bmd80	Bone mineral density QTL 80	3.2	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	10	20110614	65110614	Rat
634327	Hc4	Hypercalciuria QTL 4	2.4		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	10	1	38832698	Rat
1581497	Esta1	Estrogen-induced thymic atrophy QTL 1			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	21833758	61843633	Rat
631531	Iresp2	Immunoglobin response QTL2	6.3		blood immunoglobulin E amount (VT:0002492)	serum immunoglobulin E level (CMO:0002101)	10	23422121	32490778	Rat
631530	Tls3	T-lymphoma susceptibility QTL 3	0	0.0001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	10	27587226	96099902	Rat
2313095	Bss62	Bone structure and strength QTL 62	1.5	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
631660	Hcar1	Hepatocarcinoma resistance QTL 1	3.4	0.0001	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	10	6661118	35509383	Rat
631532	Cm50	Cardiac mass QTL 50	6.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	18035782	63035782	Rat
2300171	Bmd58	Bone mineral density QTL 58	4.9	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	27443787	72443787	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2293705	Bmd25	Bone mineral density QTL 25	7.1	0.0001	femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	10	27443787	72443787	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14991535	86964295	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14991535	107713808	Rat
2313104	Bss61	Bone structure and strength QTL 61	0.9	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6864618	96620484	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14991535	107556066	Rat
2293652	Bmd22	Bone mineral density QTL 22	4.9	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	27443787	72443787	Rat
2313055	Bw96	Body weight QTL 96	3.6	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	10	20110614	65110614	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	27023535	99451848	Rat

Markers in Region

BM386620

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	10	28,691,892 - 28,692,054 (+)	Marker Load Pipeline
mRatBN7.2	10	28,190,454 - 28,190,616 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	29,330,636 - 29,330,797	NCBI	Rnor6.0
Rnor_5.0	10	29,171,023 - 29,171,184	UniSTS	Rnor5.0
RGSC_v3.4	10	28,824,192 - 28,824,353	UniSTS	RGSC3.4
Celera	10	27,679,870 - 27,680,031	UniSTS
RH 3.4 Map	10	297.3	UniSTS
Cytogenetic Map	10	q21	UniSTS

UniSTS:236559

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	28,180,390 - 28,180,745 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	29,320,572 - 29,320,926	NCBI	Rnor6.0
Rnor_5.0	10	29,160,959 - 29,161,313	UniSTS	Rnor5.0
RGSC_v3.4	10	28,814,128 - 28,814,482	UniSTS	RGSC3.4
Celera	10	27,669,810 - 27,670,164	UniSTS
Cytogenetic Map	10	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001127296	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001414339	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006246139	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597248	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085900	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085902	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085904	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085908	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085909	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063268965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063268966	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005489805	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010055175	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010055176	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010055177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC088289	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC166858	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223393	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000067013 ⟹ ENSRNOP00000060940

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	28,656,994 - 28,696,693 (+)	Ensembl
mRatBN7.2 Ensembl	10	28,155,605 - 28,194,308 (+)	Ensembl
Rnor_6.0 Ensembl	10	29,289,203 - 29,334,478 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097586 ⟹ ENSRNOP00000080500

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	28,656,994 - 28,682,739 (+)	Ensembl
mRatBN7.2 Ensembl	10	28,155,605 - 28,180,296 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106279 ⟹ ENSRNOP00000093265

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	28,155,605 - 28,194,308 (+)	Ensembl

RefSeq Acc Id:

NM_001127296 ⟹ NP_001120768

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	28,656,994 - 28,696,693 (+)	NCBI
mRatBN7.2	10	28,155,552 - 28,195,255 (+)	NCBI
Rnor_6.0	10	29,289,203 - 29,334,498 (+)	NCBI
Rnor_5.0	10	29,128,931 - 29,175,653 (+)	NCBI
RGSC_v3.4	10	28,789,156 - 28,828,007 (+)	RGD
Celera	10	27,646,254 - 27,683,715 (+)	RGD

Sequence:

show sequence

CAGCGAGAAAATGGCGGCCGTGGCTGCTGAGGCGGCGGCGACCGCGGCGTCCCCCGGGGACGGG
GGCGCCGGTGAGGCCGAGCCGGAGCTAGAGCCCATTCCGGGCAGTGAGGCCGGCACCCCCCTCC
CGGTCACGGCCACGGAGGCGGCGGTGCCGGACGGCGAGGCCGATGGGCGCCAGTCCGCCCCTCA
GGCCGACGAGCAGCCGCTGCCGCCGCCGCCGCCGCCGCCACCGCCGGGGGAGCTGGCTGGTAGC
TCCGAGGCTGAGGAGGCGAAGCCGCCTGAGCCCGCGGCTGTCCCGGTCCCGCCGCCCGAGCAGC
CTCCGGCCGCCCCGGAGCAGCCGGAGGACGCGCCACGGCCGCCGCCAGCTCCGGCGCTCGTGCC
GCCGGCGGGCGGGGACTCAGCGGTATCGCACCTCATCCCGGGCTCGGAGGTGCGGGTCACGCTG
GACCACATCATCGAGGACGCGCTCGTGGTGTCGTTCCGCCTCGGGGAGAAGCTCTTCTCCGGGG
TCCTCATGGACCTGTCTAAAAGGTTTGGGCCCCATGGGATCCCTGTGACAGTATTTCCCAAAAG
GGAATGTAAGGACAAACCGGACGCCATGCAGCTTCAAAGTAACACATTCCAAGAAGGGATAGAA
GTCAAGCGGGAAGTGAATGGTGCTATTCCCGATGCCCTTTCTCCAGTCCCTCCTCCTGATTGCC
TGTGGACTTCCAAACCACCTCCTCTCTTCCATGAAGGAGCACCTTATCCTCCCCCCTTGTTTAT
CAGGGACACATATAACCAATCAATACCTCAGCCTCCTCCCCGGAAAATTAAGCGACCCAAACGA
AAAATGTACAGGGAAGAACCCACTTCAATAATGAATGCGATAAAGCTACGTCCCAGGCAAGTCC
TGTGTGATAAGTGTAAAAACAGTGTTGTTGCAGAAAAGAAGGAAATTAGGAAAGGTAGCAGTGA
CTCTTCTAGGTATGAAGATAAAAAACGGAGAAACGATAGTGTAGCTACTGTGAACAAAAAACTG
AAAACTGACCATAAAGTGGATGGGAAAAACCAAAACGAAAGCCAGAGAAGGAATGCTGTGGTGA
GGGTTTCCAGTATCCCTCATAGCAGGGGCAGAGTAGTCAAGGTTTCTGCTCAGGCAAATACATC
AAAAGCTCAGTTAAATACCAAGAAAGTGCTTCAGAGCAAGAACATGGATCACGCAAAAGCTCGG
GAAGTATTGAAAATTGCCAAAGAAAAGGCACAGAAGAAGCAAAGTGAAACCTCCACTTCCAAAA
ATGCGCACTCGAAAGTCCATTTCACACGCCGGTATCAGAATCCTAGCTCAGGTTCTCTCCCACC
TCGAGTGCGCTTAAAACCACAACGGTACAGGAATGAAGAAAACGACTCTTCTCTGAAGACGGGA
CTGGAGAAAATTCGGAGTGGCAAGCTGGCCCCTAAGCCGCAGTCTCGATGTACCTCCACCCGCT
CAGCAGGTCTCAACAAATGGCAGCTATTACATCAGACAGTGACGAGTCCTGCTGCTCCCTTACA
GTGTCTGACAGACCACTGTGGATTCAGACTGGGAGCATTGAAGTTAACAGTGAAGCGGGCAGCA
CAAAGACATTAGCCGACTGCTGGTTTCTTGGATGTGTACCACAGTGACAGAGCAACAGAGCAAC
AGGACTGAATAAGATTGGAGTTTTAAGCTGCACTAAGAAGTCTATGTAAAGGCAGTGACCAAAA
CCAGTCCTCTACACAAGGGCAGTTGCAAGGTAGACTGAATGGAAGGAAGGTATTAGGGAATATT
TTCTATATATAGAAGAAACAAACTGCTGCAATAAATTATGCATGAGGTGAGGAGGAAGTGGTCT
GAGCAATGTGCAGGACGCACTGAGTGGTGCGGAGGAATCACTGACAGTAGCTTCTGTTGAATGT
GAACGATAGTTTGGACAGGCCTACGAGGCAGAGGATGGTGCGGAAAGTCAGAACTGTTCGCATA
CCTAACCTTTGTGCTTTCCCCAAGGATTATGGTTATCAGTTCAGAAGTGAGCAGAGGTGTGTTT
AAAATGGCGCTCCAGTGAAACAGCAATGGTCACGTGTGCTAAGGCCAGTGTTTCCTTCGGGTGC
CAGCAGAAACGAGAGGAAGAGGAGCTGACATCCTGCTGAAAGGATGGCTAAGTGCCCCGCCCCA
CCCACAAGTAAACTGTGGATCTTTTAATAAAACAGGGCTGTGTTATCTTGAATATATGTTTGCT
TGTTAGAACATATTAAGATGTATTTATTTGCCACTAGTATTTAACATTTTGTGCACATTTTCAT
AACTACATCGTACCTTTTCCTATTTTGACTCCCAAGTGGATAGGCTAGTGTTGAGCTTGGAATG
AAATCATCCACTCCCAAGAACCAGCTCAGACTCTGAGCTGGGCAGGATTTTATTGTTGCCTCTC
CCCTTACTGAGTGGTGCTGTTCAGAAAAGGTGGCAGCATCAGTGTTGATCTGGACCACTTTCCA
CAGCAAGAACCCCTACTTCTCAGTGCAGGAGATTCTCACAGGTGTCAGGGAGGACTTGGCCCTG
GGGAACAAGTGGCAGAACAGATCCATGGAAACAGCCTAAACTTTTGGTGCATGGAACATGAATT
CTTGACAGAGACCACAGATTTTCCTTGTCTTTGCTAAATATATACTATGAAACCCCTTAATTTT
TCTTGTTTAATGAATGGAGAACACATGAGAAAATCAGATGGACCTGTTAGTACTACATTTTTAA
AGCATTTTATATTTGATGGTGCCGTAATTTTAATAATAAAACTGAAGATTTTTAGTGGCAATAC
TGATTTATTTTTTAAACCAGAAAGATAACATCATATTGATTACTTACTACAAAAAGAAAAAAAA
AAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001414339 ⟹ NP_001401268

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	28,656,994 - 28,682,739 (+)	NCBI
mRatBN7.2	10	28,155,552 - 28,181,301 (+)	NCBI

RefSeq Acc Id:

XM_006246139 ⟹ XP_006246201

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	28,655,024 - 28,696,693 (+)	NCBI
mRatBN7.2	10	28,155,512 - 28,195,255 (+)	NCBI
Rnor_6.0	10	29,288,266 - 29,335,425 (+)	NCBI
Rnor_5.0	10	29,128,931 - 29,175,653 (+)	NCBI

Sequence:

show sequence

TCTTCTTCTTTCTTTCTGCACACAGCAGGGAAGAGGGCAAGGAAAGAAAAGGCTCCAATAATCT
TTCCGTGGATTTAAGGACTTCAGTTAACTTAGCATGTCAGTTGTCTGTCTTCTCGTTAGAATTT
TCCTTTTTTTAAACTAGCAGGTCCCTAGAGATTAGTCCTTTATTTTCTAAAAAGTGAAACCAAG
GAAAGCACTGCTTGTGTGCATGCTGGAGTTCCTGTCATGTGGTTATGGAGAATGTCTTGTATGT
CGTCCCATTTCCAGCACCTCATAATCTGTCTAGCAGAATAGGCACCCAGAAAGTGTTTGAGGAT
TATTTTGGAACTTTAGTTATCTTTCCCACAGAAGCCTGTTGTGCCCACACTTGGGCACAAGCAA
ATCCACGCCTAGAAATAACATTTATTCTAAGGATCTCTGCGCAAAGATTCTTGGGAAGTGGTTC
CCCTTCTGCATTCTCCCGCTATTCCTCCCTTGGGGAGTCTTTGAAAGAACTGGCACGACTCGCG
TTTCCTTCCCATCTCCCACCTCCGAAGAACAGGCCGAGTATGGGCAGGAGCATAAACCAATCCT
AAAGCGGTATTTTCCCTCCCAACCAATAGATACAGGCTGTAAGCACAGGGCGCCGCTTTTGCCA
TCCTTCGGCCCGCCCCTCAAACTCCTTTTAGATTCGCCACTTGACAACTCACCTAACCAATGGG
AAGTTCCTACTCTGAGGGAGGGGGCGGGACCCAGCCCGCGACAGACGTCTGCTCCTGACCAATG
GGTTGACAGAAGTGAGGAAGGGGGTGGAAGGCGGAGCCAATGGCGCGGTGCCAATCACGAGCAT
CAGGGAAAGGGCGGGACGAGAGTGTTAGCGGGAGGGAGGGGAAGGCCTCGGGATCCCAGCCGCG
CTGCCGCCGCCGCCGCAGCCCGAGTCGGAGGAGGGAGAAACCAGCGAGAAAATGGCGGCCGTGG
CTGCTGAGGCGGCGGCGACCGCGGCGTCCCCCGGGGACGGGGGCGCCGGTGAGGCCGAGCCGGA
GCTAGAGCCCATTCCGGGCAGTGAGGCCGGCACCCCCCTCCCGGTCACGGCCACGGAGGCGGCG
GTGCCGGACGGCGAGGCCGATGGGCGCCAGTCCGCCCCTCAGGCCGACGAGCAGCCGCTGCCGC
CGCCGCCGCCGCCGCCACCGCCGGGGGAGCTGGCTGGTAGCTCCGAGGCTGAGGAGGCGAAGCC
GCCTGAGCCCGCGGCTGTCCCGGTCCCGCCGCCCGAGCAGCCTCCGGCCGCCCCGGAGCAGCCG
GAGGACGCGCCACGGCCGCCGCCAGCTCCGGCGCTCGTGCCGCCGGCGGGCGGGGACTCAGCGG
TATCGCACCTCATCCCGGGCTCGGAGGTGCGGGTCACGCTGGACCACATCATCGAGGACGCGCT
CGTGGTGTCGTTCCGCCTCGGGGAGAAGCTCTTCTCCGGGGTCCTCATGGACCTGTCTAAAAGG
TTTGGGCCCCATGGGATCCCTGTGACAGTATTTCCCAAAAGGGAATGTAAGGACAAACCGGACG
CCATGCAGCTTCAAAGTAACACATTCCAAGAAGGGATAGAAGTCAAGCGGGAAGTGAATGGTGC
TATTCCCGATGCCCTTTCTCCAGTCCCTCCTCCTGATTGCCTGTGGACTTCCAAACCACCTCCT
CTCTTCCATGAAGGAGCACCTTATCCTCCCCCCTTGTTTATCAGGGACACATATAACCAATCAA
TACCTCAGCCTCCTCCCCGGAAAATTAAGCGACCCAAACGAAAAATGTACAGGGAAGAACCCAC
TTCAATAATGAATGCGATAAAGCTACGTCCCAGGCAAGTCCTGTGTGATAAGTGTAAAAACAGT
GTTGTTGCAGAAAAGAAGGAAATTAGGAAAGGTAGCAGTGACTCTTCTAGGTATGAAGATAAAA
AACGGAGAAACGATAGTGTAGCTACTGTGAACAAAAAACTGAAAACTGACCATAAAGTGGATGG
GAAAAACCAAAACGAAAGCCAGAGAAGGAATGCTGTGGTGAGGGTTTCCAGTATCCCTCATAGC
AGGGGCAGAGTAGTCAAGGTTTCTGCTCAGGCAAATACATCAAAAGCTCAGTTAAATACCAAGA
AAGTGCTTCAGAGCAAGAACATGGATCACGCAAAAGCTCGGGAAGTATTGAAAATTGCCAAAGA
AAAGGCACAGAAGAAGCAAAGTGAAACCTCCACTTCCAAAAATGCGCACTCGAAAGTCCATTTC
ACACGCCGGTATCAGAATCCTAGCTCAGGTTCTCTCCCACCTCGAGTGCGCTTAAAACCACAAC
GGTACAGGAATGAAGAAAACGACTCTTCTCTGAAGACGGGACTGGAGAAAATTCGGAGTGGCAA
GCTGGCCCCTAAGCCGCAGTCTCGATGTACCTCCACCCGCTCAGCAGCACAAAGACATTAGCCG
ACTGCTGGTTTCTTGGATGTGTACCACAGTGACAGAGCAACAGAGCAACAGGACTGAATAAGAT
TGGAGTTTTAAGCTGCACTAAGAAGTCTATGTAAAGGCAGTGACCAAAACCAGTCCTCTACACA
AGGGCAGTTGCAAGGTAGACTGAATGGAAGGAAGGTATTAGGGAATATTTTCTATATATAGAAG
AAACAAACTGCTGCAATAAATTATGCATGAGGTGAGGAGGAAGTGGTCTGAGCAATGTGCAGGA
CGCACTGAGTGGTGCGGAGGAATCACTGACAGTAGCTTCTGTTGAATGTGAACGATAGTTTGGA
CAGGCCTACGAGGCAGAGGATGGTGCGGAAAGTCAGAACTGTTCGCATACCTAACCTTTGTGCT
TTCCCCAAGGATTATGGTTATCAGTTCAGAAGTGAGCAGAGGTGTGTTTAAAATGGCGCTCCAG
TGAAACAGCAATGGTCACGTGTGCTAAGGCCAGTGTTTCCTTCGGGTGCCAGCAGAAACGAGAG
GAAGAGGAGCTGACATCCTGCTGAAAGGATGGCTAAGTGCCCCGCCCCACCCACAAGTAAACTG
TGGATCTTTTAATAAAACAGGGCTGTGTTATCTTGAATATATGTTTGCTTGTTAGAACATATTA
AGATGTATTTATTTGCCACTAGTATTTAACATTTTGTGCACATTTTCATAACTACATCGTACCT
TTTCCTATTTTGACTCCCAAGTGGATAGGCTAGTGTTGAGCTTGGAATGAAATCATCCACTCCC
AAGAACCAGCTCAGACTCTGAGCTGGGCAGGATTTTATTGTTGCCTCTCCCCTTACTGAGTGGT
GCTGTTCAGAAAAGGTGGCAGCATCAGTGTTGATCTGGACCACTTTCCACAGCAAGAACCCCTA
CTTCTCAGTGCAGGAGATTCTCACAGGTGTCAGGGAGGACTTGGCCCTGGGGAACAAGTGGCAG
AACAGATCCATGGAAACAGCCTAAACTTTTGGTGCATGGAACATGAATTCTTGACAGAGACCAC
AGATTTTCCTTGTCTTTGCTAAATATATACTATGAAACCCCTTAATTTTTCTTGTTTAATGAAT
GGAGAACACATGAGAAAATCAGATGGACCTGTTAGTACTACATTTTTAAAGCATTTTATATTTG
ATGGTGCCGTAATTTTAATAATAAAACTGAAGATTTTTAGTGGCAATACTGATTTATTTTTTAA
ACCAGAAAGATAACATCATATTGATTACTTACTACAAAAAGAAAAAAAAAAAAGAAGAAAAAAA
GCCAAAAGAAAAGAACTAACTCACAGTACTCATCAAAGCAACACGAGTGACGAGTGGGCACTTG
GCTCAAGAGCTCACTGCCTGTGAGCTTTCTCTGTGGGTGACAGCACCCAACAGCCCACTGCTCA
GGACTAGGAAATGCTCTGGGTGGGACTTTTAGATCATTTGCTATACCTGACTGTGATTTGATTT
GTAACTCAAGAAGAAAAGCCGGGTAGTCTGGAGTCTAGTGAGCTTAATTCAGATCCTAACACAC
TGCAAGTGCTGGGAAGTCCTGACTGCATTTTACAATGATCTCTTCGGAGACTTCCACACCATGA
CGTCATCTTACCAAATGGGCTCAGGAACTCTAACAGCAGGGAGCTGTGGGGAGGCCGTGAATCA
CAGCTCCAGGCTCTGGGGCCCGTCTTAGGCCCCAACACCAGCAGTACCTTTCATGCTCACTCAG
GAACCAGGTGTCTCCCAAGCCATGTGGAATTATGCATGGATTGTATCAGGAAGACCTTTAAGCT
TTAGAAATCTTTATTTGTAGAGTGATGGAATTGACCAAAAAATAATATTAAAAAGGCAAAAGCA
CTGGGAGAGATCAGGTTTTAAGAATTTACGTATTTTTTTTTCCCTTATGGCAAATCCTTAAAGG
CCTTTTATTACAAATTAGATTTTCATTAAAAAAGAAAGGACACTTGGTGGTATTTAAAATCTAG
GCCTACCATGTTACAACTTCATTTTTTATTGCTTTAGTTGCTTAATATTTAAGCTCTGCTTCAT
GCTACCTTTTGTCTGTATTAAAATCTTCACAGGCCTATTTCATTTGTAGACTTGAATTGTTTCT
CCCTTCCATCTGCTTGGAGTTAAATGTTAAAGAATGTTGTGTAAAGTGTTATCCAATAAAGTCT
TTGATTTTTTTTTAAATTTA

hide sequence

RefSeq Acc Id:

XM_039085900 ⟹ XP_038941828

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	28,657,587 - 28,682,739 (+)	NCBI
mRatBN7.2	10	28,156,468 - 28,181,301 (+)	NCBI

RefSeq Acc Id:

XM_039085901 ⟹ XP_038941829

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	28,657,587 - 28,682,739 (+)	NCBI
mRatBN7.2	10	28,156,468 - 28,181,301 (+)	NCBI

RefSeq Acc Id:

XM_039085902 ⟹ XP_038941830

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	28,657,587 - 28,682,739 (+)	NCBI
mRatBN7.2	10	28,156,468 - 28,181,301 (+)	NCBI

RefSeq Acc Id:

XM_039085904 ⟹ XP_038941832

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	28,659,186 - 28,682,739 (+)	NCBI
mRatBN7.2	10	28,159,740 - 28,181,301 (+)	NCBI

RefSeq Acc Id:

XM_039085905 ⟹ XP_038941833

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	28,665,877 - 28,682,739 (+)	NCBI
mRatBN7.2	10	28,169,696 - 28,181,301 (+)	NCBI

RefSeq Acc Id:

XM_039085908 ⟹ XP_038941836

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	28,654,279 - 28,680,204 (+)	NCBI
mRatBN7.2	10	28,155,509 - 28,178,767 (+)	NCBI

RefSeq Acc Id:

XM_039085909 ⟹ XP_038941837

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	28,654,278 - 28,670,196 (+)	NCBI
mRatBN7.2	10	28,155,509 - 28,168,756 (+)	NCBI

RefSeq Acc Id:

XM_063268965 ⟹ XP_063125035

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	28,657,587 - 28,682,739 (+)	NCBI

RefSeq Acc Id:

XM_063268966 ⟹ XP_063125036

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	28,665,877 - 28,682,739 (+)	NCBI

RefSeq Acc Id:

XR_005489805

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	28,654,278 - 28,680,205 (+)	NCBI
mRatBN7.2	10	28,155,509 - 28,178,767 (+)	NCBI

RefSeq Acc Id:

XR_010055175

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	28,654,272 - 28,680,134 (+)	NCBI

RefSeq Acc Id:

XR_010055176

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	28,654,276 - 28,680,134 (+)	NCBI

RefSeq Acc Id:

XR_010055177

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	28,654,284 - 28,680,134 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001120768	(Get FASTA)	NCBI Sequence Viewer
	NP_001401268	(Get FASTA)	NCBI Sequence Viewer
	XP_006246201	(Get FASTA)	NCBI Sequence Viewer
	XP_038941828	(Get FASTA)	NCBI Sequence Viewer
	XP_038941829	(Get FASTA)	NCBI Sequence Viewer
	XP_038941830	(Get FASTA)	NCBI Sequence Viewer
	XP_038941832	(Get FASTA)	NCBI Sequence Viewer
	XP_038941833	(Get FASTA)	NCBI Sequence Viewer
	XP_038941836	(Get FASTA)	NCBI Sequence Viewer
	XP_038941837	(Get FASTA)	NCBI Sequence Viewer
	XP_063125035	(Get FASTA)	NCBI Sequence Viewer
	XP_063125036	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI66858	(Get FASTA)	NCBI Sequence Viewer
	EDM04140	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000060940
	ENSRNOP00000060940.1
	ENSRNOP00000080500
	ENSRNOP00000080500.1

RefSeq Acc Id:	NP_001120768 ⟸ NM_001127296
- Peptide Label:	isoform 2
- UniProtKB:	B2RYP9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAVAAEAAATAASPGDGGAGEAEPELEPIPGSEAGTPLPVTATEAAVPDGEADGRQSAPQADE QPLPPPPPPPPPGELAGSSEAEEAKPPEPAAVPVPPPEQPPAAPEQPEDAPRPPPAPALVPPAG GDSAVSHLIPGSEVRVTLDHIIEDALVVSFRLGEKLFSGVLMDLSKRFGPHGIPVTVFPKRECK DKPDAMQLQSNTFQEGIEVKREVNGAIPDALSPVPPPDCLWTSKPPPLFHEGAPYPPPLFIRDT YNQSIPQPPPRKIKRPKRKMYREEPTSIMNAIKLRPRQVLCDKCKNSVVAEKKEIRKGSSDSSR YEDKKRRNDSVATVNKKLKTDHKVDGKNQNESQRRNAVVRVSSIPHSRGRVVKVSAQANTSKAQ LNTKKVLQSKNMDHAKAREVLKIAKEKAQKKQSETSTSKNAHSKVHFTRRYQNPSSGSLPPRVR LKPQRYRNEENDSSLKTGLEKIRSGKLAPKPQSRCTSTRSAGLNKWQLLHQTVTSPAAPLQCLT DHCGFRLGALKLTVKRAAQRH hide sequence

RefSeq Acc Id:	XP_006246201 ⟸ XM_006246139
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6GK76 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAVAAEAAATAASPGDGGAGEAEPELEPIPGSEAGTPLPVTATEAAVPDGEADGRQSAPQADE QPLPPPPPPPPPGELAGSSEAEEAKPPEPAAVPVPPPEQPPAAPEQPEDAPRPPPAPALVPPAG GDSAVSHLIPGSEVRVTLDHIIEDALVVSFRLGEKLFSGVLMDLSKRFGPHGIPVTVFPKRECK DKPDAMQLQSNTFQEGIEVKREVNGAIPDALSPVPPPDCLWTSKPPPLFHEGAPYPPPLFIRDT YNQSIPQPPPRKIKRPKRKMYREEPTSIMNAIKLRPRQVLCDKCKNSVVAEKKEIRKGSSDSSR YEDKKRRNDSVATVNKKLKTDHKVDGKNQNESQRRNAVVRVSSIPHSRGRVVKVSAQANTSKAQ LNTKKVLQSKNMDHAKAREVLKIAKEKAQKKQSETSTSKNAHSKVHFTRRYQNPSSGSLPPRVR LKPQRYRNEENDSSLKTGLEKIRSGKLAPKPQSRCTSTRSAAQRH hide sequence

Ensembl Acc Id:

ENSRNOP00000060940 ⟸ ENSRNOT00000067013

RefSeq Acc Id:	XP_038941836 ⟸ XM_039085908
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038941837 ⟸ XM_039085909
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038941829 ⟸ XM_039085901
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038941828 ⟸ XM_039085900
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038941830 ⟸ XM_039085902
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038941832 ⟸ XM_039085904
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038941833 ⟸ XM_039085905
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000093265 ⟸ ENSRNOT00000106279

Ensembl Acc Id:

ENSRNOP00000080500 ⟸ ENSRNOT00000097586

RefSeq Acc Id:	NP_001401268 ⟸ NM_001414339
- Peptide Label:	isoform 1
- UniProtKB:	A0A8I5ZT71 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063125035 ⟸ XM_063268965
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063125036 ⟸ XM_063268966
- Peptide Label:	isoform X1

Protein Domains

PWWP

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B2RYP9-F1-model_v2	AlphaFold	B2RYP9	1-533	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697117

Promoter ID:

EPDNEW_R7641

Type:

initiation region

Name:

Pwwp2a_1

Description:

PWWP domain containing 2A

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	29,289,155 - 29,289,215	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305891	AgrOrtholog
BioCyc Gene	G2FUF-25440	BioCyc
Ensembl Genes	ENSRNOG00000003936	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000067013	ENTREZGENE
	ENSRNOT00000067013.3	UniProtKB/TrEMBL
	ENSRNOT00000097586	ENTREZGENE
	ENSRNOT00000097586.2	UniProtKB/TrEMBL
Gene3D-CATH	2.30.30.140	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:9100439	IMAGE-MGC_LOAD
InterPro	PWWP_dom	UniProtKB/TrEMBL
KEGG Report	rno:303060	UniProtKB/TrEMBL
MGC_CLONE	MGC:188765	IMAGE-MGC_LOAD
NCBI Gene	303060	ENTREZGENE
PANTHER	LP07818P1	UniProtKB/TrEMBL
	RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG	UniProtKB/TrEMBL
Pfam	PWWP	UniProtKB/TrEMBL
PhenoGen	Pwwp2a	PhenoGen
PROSITE	PWWP	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000003936	RatGTEx
SMART	PWWP	UniProtKB/TrEMBL
Superfamily-SCOP	Tudor/PWWP/MBT	UniProtKB/TrEMBL
UniProt	A0A8I5ZT71	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GK76	ENTREZGENE
	B2RYP9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-05-24	Pwwp2a	PWWP domain containing 2A	LOC683932	similar to PWWP domain containing 2	Data merged from RGD:1596562	1643240	APPROVED
2008-03-07	Pwwp2a	PWWP domain containing 2A	RGD1305891_predicted	similar to DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA) (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC683932	similar to PWWP domain containing 2			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-01-20	RGD1305891_predicted	similar to DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA) (predicted)	LOC303060_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC303060_predicted	similar to DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA) (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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