Klhl21 (kelch-like family member 21) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Klhl21 (kelch-like family member 21) Rattus norvegicus
Analyze
Symbol: Klhl21
Name: kelch-like family member 21
RGD ID: 1305863
Description: Predicted to enable cullin family protein binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in chromosome passenger complex localization to spindle midzone; protein ubiquitination; and regulation of cytokinesis. Predicted to be located in polar microtubule. Predicted to be part of Cul3-RING ubiquitin ligase complex. Orthologous to human KLHL21 (kelch like family member 21); INTERACTS WITH aflatoxin B1; bisphenol A; C60 fullerene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: kelch-like 21; kelch-like 21 (Drosophila); kelch-like protein 21; LOC313743; RGD1305863; similar to Hypothetical protein KIAA0469
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85167,797,621 - 167,806,276 (+)NCBIGRCr8
mRatBN7.25162,514,888 - 162,523,545 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5162,514,765 - 162,523,545 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5165,217,955 - 165,226,725 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05167,038,924 - 167,047,582 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05167,001,124 - 167,009,782 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05169,181,418 - 169,190,073 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5169,181,418 - 169,190,073 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05172,740,028 - 172,748,683 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45169,236,427 - 169,246,001 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15169,246,580 - 169,254,165 (+)NCBI
Celera5160,747,612 - 160,756,322 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
alpha-pinene  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
C60 fullerene  (EXP)
captan  (ISO)
carbon nanotube  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP,ISO)
copper(II) sulfate  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
diarsenic trioxide  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
fenthion  (ISO)
fluoranthene  (ISO)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
hexane  (EXP)
hydrogen peroxide  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
methamphetamine  (ISO)
methidathion  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
orphenadrine  (EXP)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
sulforaphane  (ISO)
sulindac sulfide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14528312   PMID:19995937  


Genomics

Comparative Map Data
Klhl21
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85167,797,621 - 167,806,276 (+)NCBIGRCr8
mRatBN7.25162,514,888 - 162,523,545 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5162,514,765 - 162,523,545 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5165,217,955 - 165,226,725 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05167,038,924 - 167,047,582 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05167,001,124 - 167,009,782 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05169,181,418 - 169,190,073 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5169,181,418 - 169,190,073 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05172,740,028 - 172,748,683 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45169,236,427 - 169,246,001 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15169,246,580 - 169,254,165 (+)NCBI
Celera5160,747,612 - 160,756,322 (+)NCBICelera
Cytogenetic Map5q36NCBI
KLHL21
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816,590,724 - 6,602,869 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16,590,724 - 6,614,607 (-)EnsemblGRCh38hg38GRCh38
GRCh3716,650,784 - 6,662,929 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3616,573,371 - 6,585,516 (-)NCBINCBI36Build 36hg18NCBI36
Build 3416,585,050 - 6,597,195NCBI
Celera15,764,642 - 5,776,787 (-)NCBICelera
Cytogenetic Map1p36.31NCBI
HuRef15,798,711 - 5,810,856 (-)NCBIHuRef
CHM1_116,639,510 - 6,651,654 (-)NCBICHM1_1
T2T-CHM13v2.016,116,388 - 6,128,533 (-)NCBIT2T-CHM13v2.0
Klhl21
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394152,093,348 - 152,102,134 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4152,093,260 - 152,102,137 (+)EnsemblGRCm39 Ensembl
GRCm384152,008,891 - 152,017,677 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4152,008,803 - 152,017,680 (+)EnsemblGRCm38mm10GRCm38
MGSCv374151,383,000 - 151,391,786 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364150,852,691 - 150,861,477 (+)NCBIMGSCv36mm8
Celera4154,295,035 - 154,303,821 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map482.82NCBI
Klhl21
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554866,038,291 - 6,047,814 (+)NCBIChiLan1.0ChiLan1.0
KLHL21
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21221,625,159 - 221,637,412 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11220,267,327 - 220,279,514 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v015,352,020 - 5,364,268 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.116,604,801 - 6,616,890 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16,604,801 - 6,616,890 (-)Ensemblpanpan1.1panPan2
KLHL21
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1560,415,493 - 60,427,301 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl560,413,552 - 60,427,609 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha560,425,033 - 60,436,809 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0560,631,172 - 60,643,210 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl560,631,250 - 60,643,259 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1560,630,243 - 60,642,281 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0560,496,924 - 60,508,708 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0560,900,730 - 60,911,153 (-)NCBIUU_Cfam_GSD_1.0
Klhl21
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505830,859,365 - 30,870,408 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366231,344,622 - 1,355,739 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366231,344,603 - 1,355,594 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL21
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl667,420,622 - 67,434,812 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1667,420,618 - 67,434,812 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2662,395,591 - 62,405,728 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL21
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120125,142,580 - 125,156,153 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20125,143,114 - 125,157,484 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605429,187,672 - 29,201,242 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klhl21
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248184,931,296 - 4,942,199 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248184,931,288 - 4,941,363 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Klhl21
35 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:637
Count of miRNA genes:268
Interacting mature miRNAs:341
Transcripts:ENSRNOT00000004508
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5151113452164465185Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat

Markers in Region
RH131355  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25162,523,216 - 162,523,414 (+)MAPPERmRatBN7.2
Rnor_6.05169,189,745 - 169,189,942NCBIRnor6.0
Rnor_5.05172,748,355 - 172,748,552UniSTSRnor5.0
RGSC_v3.45169,245,673 - 169,245,870UniSTSRGSC3.4
Celera5160,755,994 - 160,756,191UniSTS
RH 3.4 Map51141.1UniSTS
Cytogenetic Map5q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 43 17 2 9 2 8 11 10 22 26 10 8
Low 3 40 39 10 39 64 13 15 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000004508   ⟹   ENSRNOP00000004508
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5162,514,765 - 162,523,545 (+)Ensembl
Rnor_6.0 Ensembl5169,181,418 - 169,190,073 (+)Ensembl
RefSeq Acc Id: NM_001107996   ⟹   NP_001101466
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85167,797,621 - 167,806,276 (+)NCBI
mRatBN7.25162,514,888 - 162,523,545 (+)NCBI
Rnor_6.05169,181,418 - 169,190,073 (+)NCBI
Rnor_5.05172,740,028 - 172,748,683 (+)NCBI
RGSC_v3.45169,236,427 - 169,246,001 (+)RGD
Celera5160,747,612 - 160,756,322 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001101466 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein D4A2K4 (Get FASTA)   NCBI Sequence Viewer  
  EDL81211 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000004508
  ENSRNOP00000004508.5
  ENSRNOP00055021501
  ENSRNOP00060004249
  ENSRNOP00065011742
Reference Protein Sequences
RefSeq Acc Id: NP_001101466   ⟸   NM_001107996
- UniProtKB: D4A2K4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000004508   ⟸   ENSRNOT00000004508
Protein Domains
BACK   BTB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A2K4-F1-model_v2 AlphaFold D4A2K4 1-597 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694295
Promoter ID:EPDNEW_R4818
Type:single initiation site
Name:Klhl21_1
Description:kelch-like family member 21
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05169,181,390 - 169,181,450EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305863 AgrOrtholog
BioCyc Gene G2FUF-39028 BioCyc
Ensembl Genes ENSRNOG00000003334 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055015527 UniProtKB/Swiss-Prot
  ENSRNOG00060003558 UniProtKB/Swiss-Prot
  ENSRNOG00065009694 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000004508 ENTREZGENE
  ENSRNOT00000004508.6 UniProtKB/Swiss-Prot
  ENSRNOT00055026480 UniProtKB/Swiss-Prot
  ENSRNOT00060005826 UniProtKB/Swiss-Prot
  ENSRNOT00065015569 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.420 UniProtKB/Swiss-Prot
  2.120.10.80 UniProtKB/Swiss-Prot
InterPro BACK UniProtKB/Swiss-Prot
  BTB-kelch_protein UniProtKB/Swiss-Prot
  BTB/POZ_dom UniProtKB/Swiss-Prot
  Kelch-typ_b-propeller UniProtKB/Swiss-Prot
  Kelch_1 UniProtKB/Swiss-Prot
  KLHL21 UniProtKB/Swiss-Prot
  KLHL21_BACK UniProtKB/Swiss-Prot
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot
KEGG Report rno:313743 UniProtKB/Swiss-Prot
NCBI Gene 313743 ENTREZGENE
PANTHER ACTIN-BINDING PROTEIN IPP UniProtKB/Swiss-Prot
  KELCH PROTEIN UniProtKB/Swiss-Prot
Pfam BACK UniProtKB/Swiss-Prot
  BTB UniProtKB/Swiss-Prot
  Kelch_1 UniProtKB/Swiss-Prot
  Kelch_6 UniProtKB/Swiss-Prot
PhenoGen Klhl21 PhenoGen
PIRSF Kelch-like_protein_gigaxonin UniProtKB/Swiss-Prot
PROSITE BTB UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000003334 RatGTEx
  ENSRNOG00055015527 RatGTEx
  ENSRNOG00060003558 RatGTEx
  ENSRNOG00065009694 RatGTEx
SMART BACK UniProtKB/Swiss-Prot
  BTB UniProtKB/Swiss-Prot
  Kelch UniProtKB/Swiss-Prot
Superfamily-SCOP SSF117281 UniProtKB/Swiss-Prot
  SSF54695 UniProtKB/Swiss-Prot
UniProt D4A2K4 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-06 Klhl21  kelch-like family member 21  Klhl21  kelch-like 21 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Klhl21  kelch-like 21 (Drosophila)   Klhl21_predicted  kelch-like 21 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Klhl21_predicted  kelch-like 21 (Drosophila) (predicted)  RGD1305863_predicted  similar to Hypothetical protein KIAA0469 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1305863_predicted  similar to Hypothetical protein KIAA0469 (predicted)  LOC313743_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC313743_predicted  similar to Hypothetical protein KIAA0469 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL