Klhl21 (kelch-like family member 21) - Rat Genome Database

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Gene: Klhl21 (kelch-like family member 21) Rattus norvegicus
Analyze
Symbol: Klhl21
Name: kelch-like family member 21
RGD ID: 1305863
Description: Predicted to enable cullin family protein binding activity and ubiquitin-like ligase-substrate adaptor activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including chromosome passenger complex localization to spindle midzone; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to be located in polar microtubule. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human KLHL21 (kelch like family member 21); INTERACTS WITH aflatoxin B1; bisphenol A; C60 fullerene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: kelch-like 21; kelch-like 21 (Drosophila); kelch-like protein 21; LOC313743; RGD1305863; similar to Hypothetical protein KIAA0469
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85167,797,621 - 167,806,276 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5167,797,591 - 167,806,276 (+)EnsemblGRCr8
mRatBN7.25162,514,888 - 162,523,545 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5162,514,765 - 162,523,545 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5165,217,955 - 165,226,725 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05167,038,924 - 167,047,582 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05167,001,124 - 167,009,782 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05169,181,418 - 169,190,073 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5169,181,418 - 169,190,073 (+)Ensemblrn6Rnor6.0
Rnor_5.05172,740,028 - 172,748,683 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45169,236,427 - 169,246,001 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5160,747,612 - 160,756,322 (+)NCBICelera
RGSC_v3.15169,246,580 - 169,254,165 (+)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
Ependymomas  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
alpha-pinene  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
C60 fullerene  (EXP)
captan  (ISO)
carbon nanotube  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP,ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (EXP)
diarsenic trioxide  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
fenthion  (ISO)
fluoranthene  (ISO)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
GSK-J4  (ISO)
hexane  (EXP)
hydrogen peroxide  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mercury dibromide  (ISO)
methamphetamine  (ISO)
methidathion  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
okadaic acid  (ISO)
orphenadrine  (EXP)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
sulforaphane  (ISO)
sulindac sulfide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centrosome  (IEA,ISO)
Cul3-RING ubiquitin ligase complex  (IBA,IEA,ISO,ISS)
cytoplasm  (IBA)
polar microtubule  (IEA,ISO,ISS)
spindle  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14528312   PMID:19995937  


Genomics

Comparative Map Data
Klhl21
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85167,797,621 - 167,806,276 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5167,797,591 - 167,806,276 (+)EnsemblGRCr8
mRatBN7.25162,514,888 - 162,523,545 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5162,514,765 - 162,523,545 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5165,217,955 - 165,226,725 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05167,038,924 - 167,047,582 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05167,001,124 - 167,009,782 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05169,181,418 - 169,190,073 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5169,181,418 - 169,190,073 (+)Ensemblrn6Rnor6.0
Rnor_5.05172,740,028 - 172,748,683 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45169,236,427 - 169,246,001 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5160,747,612 - 160,756,322 (+)NCBICelera
RGSC_v3.15169,246,580 - 169,254,165 (+)NCBI
Cytogenetic Map5q36NCBI
KLHL21
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816,590,724 - 6,602,869 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16,590,724 - 6,614,607 (-)Ensemblhg38GRCh38
GRCh3716,650,784 - 6,662,929 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3616,573,371 - 6,585,516 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3416,585,050 - 6,597,195NCBI
Celera15,764,642 - 5,776,787 (-)NCBICelera
Cytogenetic Map1p36.31NCBI
HuRef15,798,711 - 5,810,856 (-)NCBIHuRef
CHM1_116,639,510 - 6,651,654 (-)NCBICHM1_1
T2T-CHM13v2.016,116,388 - 6,128,533 (-)NCBIT2T-CHM13v2.0
Klhl21
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394152,093,348 - 152,102,134 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4152,093,260 - 152,102,137 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm384152,008,891 - 152,017,677 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4152,008,803 - 152,017,680 (+)Ensemblmm10GRCm38
MGSCv374151,383,000 - 151,391,786 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364150,852,691 - 150,861,477 (+)NCBIMGSCv36mm8
Celera4154,295,035 - 154,303,821 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map482.82NCBI
Klhl21
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554866,038,291 - 6,044,814 (+)Ensembl
ChiLan1.0NW_0049554866,038,291 - 6,047,814 (+)NCBIChiLan1.0ChiLan1.0
KLHL21
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21221,625,159 - 221,637,412 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11220,267,327 - 220,279,514 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v015,352,020 - 5,364,268 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.116,604,801 - 6,616,890 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16,604,801 - 6,616,890 (-)EnsemblpanPan2panpan1.1
KLHL21
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1560,415,493 - 60,427,301 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl560,413,552 - 60,427,609 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha560,425,033 - 60,436,809 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0560,631,172 - 60,643,210 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl560,631,250 - 60,643,259 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1560,630,243 - 60,642,281 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0560,496,924 - 60,508,708 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0560,900,730 - 60,911,153 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Klhl21
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505830,859,365 - 30,870,408 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366231,344,622 - 1,355,739 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366231,344,603 - 1,355,594 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL21
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl667,420,622 - 67,434,812 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1667,420,618 - 67,434,812 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2662,395,591 - 62,405,728 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL21
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120125,142,580 - 125,156,153 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20125,143,114 - 125,157,484 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605429,187,672 - 29,201,242 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klhl21
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248184,931,296 - 4,942,199 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248184,931,288 - 4,941,363 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Klhl21
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v118,722,939 - 8,731,627 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:637
Count of miRNA genes:268
Interacting mature miRNAs:341
Transcripts:ENSRNOT00000004508
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5149642129171146538Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5160111176171146538Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5156396728172190305Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138002522170842766Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5156289283171137955Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5160071170172129029Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)5141764300172190305Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5148093485172129029Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat

Markers in Region
RH131355  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25162,523,216 - 162,523,414 (+)MAPPERmRatBN7.2
Rnor_6.05169,189,745 - 169,189,942NCBIRnor6.0
Rnor_5.05172,748,355 - 172,748,552UniSTSRnor5.0
RGSC_v3.45169,245,673 - 169,245,870UniSTSRGSC3.4
Celera5160,755,994 - 160,756,191UniSTS
RH 3.4 Map51141.1UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 91 59 6 355 191 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000004508   ⟹   ENSRNOP00000004508
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5167,797,591 - 167,806,276 (+)Ensembl
mRatBN7.2 Ensembl5162,514,765 - 162,523,545 (+)Ensembl
Rnor_6.0 Ensembl5169,181,418 - 169,190,073 (+)Ensembl
RefSeq Acc Id: NM_001107996   ⟹   NP_001101466
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85167,797,621 - 167,806,276 (+)NCBI
mRatBN7.25162,514,888 - 162,523,545 (+)NCBI
Rnor_6.05169,181,418 - 169,190,073 (+)NCBI
Rnor_5.05172,740,028 - 172,748,683 (+)NCBI
RGSC_v3.45169,236,427 - 169,246,001 (+)RGD
Celera5160,747,612 - 160,756,322 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001101466 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein D4A2K4 (Get FASTA)   NCBI Sequence Viewer  
  EDL81211 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000004508
  ENSRNOP00000004508.5
RefSeq Acc Id: NP_001101466   ⟸   NM_001107996
- UniProtKB: D4A2K4 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004508   ⟸   ENSRNOT00000004508
Protein Domains
BACK   BTB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A2K4-F1-model_v2 AlphaFold D4A2K4 1-597 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694295
Promoter ID:EPDNEW_R4818
Type:single initiation site
Name:Klhl21_1
Description:kelch-like family member 21
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05169,181,390 - 169,181,450EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305863 AgrOrtholog
BioCyc Gene G2FUF-39028 BioCyc
Ensembl Genes ENSRNOG00000003334 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000004508 ENTREZGENE
  ENSRNOT00000004508.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.420 UniProtKB/Swiss-Prot
  2.120.10.80 UniProtKB/Swiss-Prot
  Potassium Channel Kv1.1, Chain A UniProtKB/Swiss-Prot
InterPro BACK UniProtKB/Swiss-Prot
  BTB-kelch_protein UniProtKB/Swiss-Prot
  BTB/POZ_dom UniProtKB/Swiss-Prot
  Kelch-typ_b-propeller UniProtKB/Swiss-Prot
  Kelch_1 UniProtKB/Swiss-Prot
  KLHL21 UniProtKB/Swiss-Prot
  KLHL21_BACK UniProtKB/Swiss-Prot
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot
KEGG Report rno:313743 UniProtKB/Swiss-Prot
NCBI Gene 313743 ENTREZGENE
PANTHER KELCH-LIKE PROTEIN 31 UniProtKB/Swiss-Prot
  LD33804P UniProtKB/Swiss-Prot
Pfam BACK UniProtKB/Swiss-Prot
  BTB UniProtKB/Swiss-Prot
  Kelch_1 UniProtKB/Swiss-Prot
  Kelch_6 UniProtKB/Swiss-Prot
PhenoGen Klhl21 PhenoGen
PIRSF Kelch-like_protein_gigaxonin UniProtKB/Swiss-Prot
PROSITE BTB UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000003334 RatGTEx
SMART BACK UniProtKB/Swiss-Prot
  BTB UniProtKB/Swiss-Prot
  Kelch UniProtKB/Swiss-Prot
Superfamily-SCOP SSF117281 UniProtKB/Swiss-Prot
  SSF54695 UniProtKB/Swiss-Prot
UniProt D4A2K4 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-06 Klhl21  kelch-like family member 21  Klhl21  kelch-like 21 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Klhl21  kelch-like 21 (Drosophila)   Klhl21_predicted  kelch-like 21 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Klhl21_predicted  kelch-like 21 (Drosophila) (predicted)  RGD1305863_predicted  similar to Hypothetical protein KIAA0469 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1305863_predicted  similar to Hypothetical protein KIAA0469 (predicted)  LOC313743_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC313743_predicted  similar to Hypothetical protein KIAA0469 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL