Plek2 (pleckstrin 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Plek2 (pleckstrin 2) Rattus norvegicus
Analyze
Symbol: Plek2
Name: pleckstrin 2
RGD ID: 1305786
Description: Predicted to enable phosphatidylinositol-3,4-bisphosphate binding activity; phosphatidylinositol-3,5-bisphosphate binding activity; and phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in actin cytoskeleton organization and positive regulation of plasma membrane bounded cell projection assembly. Predicted to act upstream of or within positive regulation of cell projection organization. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human PLEK2 (pleckstrin 2); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC314260; pleckstrin-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86103,434,156 - 103,452,457 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6103,434,156 - 103,452,371 (-)EnsemblGRCr8
mRatBN7.2697,700,123 - 97,719,417 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl697,701,106 - 97,719,326 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx698,130,640 - 98,148,857 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0698,429,802 - 98,448,020 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0697,816,740 - 97,834,968 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd6104,975,747 - 104,993,974 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive6104,382,715 - 104,400,942 (-)NCBILyon_Normotensive
Lyon_Hypertensive6102,176,320 - 102,194,545 (-)NCBILyon_Hypertensive
F344_StmMcwi6101,331,108 - 101,349,339 (-)NCBIF344_StmMcwi
Rnor_6.06102,076,736 - 102,095,002 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6102,075,632 - 102,095,201 (-)Ensemblrn6Rnor6.0
Rnor_5.06111,450,714 - 111,468,929 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46101,523,558 - 101,541,773 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera696,089,052 - 96,107,265 (-)NCBICelera
RGSC_v3.16101,527,012 - 101,547,913 (-)NCBI
Cytogenetic Map6q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
cefaloridine  (EXP)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
copper(II) chloride  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
ethylparaben  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
furan  (EXP)
glycidol  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
nitrofen  (EXP)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
pentanal  (ISO)
perfluorooctanoic acid  (EXP)
pirinixic acid  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
propanal  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sotorasib  (ISO)
sulfadimethoxine  (EXP)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trametinib  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoskeleton  (IEA)
lamellipodium membrane  (IEA)
membrane  (IEA,ISO)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10419454   PMID:10548495   PMID:11001876   PMID:17008542   PMID:24747950  


Genomics

Comparative Map Data
Plek2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86103,434,156 - 103,452,457 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6103,434,156 - 103,452,371 (-)EnsemblGRCr8
mRatBN7.2697,700,123 - 97,719,417 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl697,701,106 - 97,719,326 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx698,130,640 - 98,148,857 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0698,429,802 - 98,448,020 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0697,816,740 - 97,834,968 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd6104,975,747 - 104,993,974 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive6104,382,715 - 104,400,942 (-)NCBILyon_Normotensive
Lyon_Hypertensive6102,176,320 - 102,194,545 (-)NCBILyon_Hypertensive
F344_StmMcwi6101,331,108 - 101,349,339 (-)NCBIF344_StmMcwi
Rnor_6.06102,076,736 - 102,095,002 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6102,075,632 - 102,095,201 (-)Ensemblrn6Rnor6.0
Rnor_5.06111,450,714 - 111,468,929 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46101,523,558 - 101,541,773 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera696,089,052 - 96,107,265 (-)NCBICelera
RGSC_v3.16101,527,012 - 101,547,913 (-)NCBI
Cytogenetic Map6q24NCBI
PLEK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381467,386,984 - 67,412,165 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1467,385,652 - 67,412,176 (-)Ensemblhg38GRCh38
GRCh371467,853,701 - 67,878,882 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361466,923,453 - 66,948,581 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341466,923,452 - 66,948,581NCBI
Celera1447,912,754 - 47,937,883 (-)NCBICelera
Cytogenetic Map14q23.3-q24.1NCBI
HuRef1448,023,619 - 48,048,753 (-)NCBIHuRef
CHM1_11467,792,390 - 67,817,515 (-)NCBICHM1_1
T2T-CHM13v2.01461,594,107 - 61,619,283 (-)NCBIT2T-CHM13v2.0
Plek2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391278,935,465 - 78,955,166 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1278,935,465 - 78,953,738 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381278,888,691 - 78,907,172 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1278,888,691 - 78,906,964 (-)Ensemblmm10GRCm38
MGSCv371279,989,684 - 80,007,925 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361279,807,534 - 79,825,790 (-)NCBIMGSCv36mm8
Celera1280,353,157 - 80,371,395 (-)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1235.51NCBI
Plek2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554662,817,939 - 2,836,688 (+)Ensembl
ChiLan1.0NW_0049554662,818,004 - 2,836,688 (+)NCBIChiLan1.0ChiLan1.0
PLEK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21568,492,488 - 68,520,652 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11467,709,000 - 67,737,166 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01447,962,082 - 47,990,237 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11466,840,321 - 66,868,249 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1466,840,329 - 66,868,249 (-)EnsemblpanPan2panpan1.1
PLEK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1841,373,779 - 41,394,718 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl841,281,509 - 41,393,351 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha841,065,508 - 41,085,367 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0841,601,165 - 41,621,034 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl841,600,912 - 41,620,981 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1841,220,002 - 41,239,867 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0841,293,684 - 41,313,523 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0841,652,639 - 41,672,663 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Plek2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864063,392,617 - 63,421,277 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649510,768,704 - 10,798,628 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649510,772,730 - 10,784,319 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl791,109,455 - 91,132,843 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1791,110,327 - 91,133,210 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2797,419,097 - 97,442,633 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLEK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12444,626,830 - 44,654,620 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2444,622,248 - 44,653,976 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605332,855,246 - 32,883,942 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plek2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473433,586,482 - 33,621,114 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473433,586,527 - 33,621,114 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Plek2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1793,000,606 - 93,020,797 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Plek2
82 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:59
Count of miRNA genes:52
Interacting mature miRNAs:58
Transcripts:ENSRNOT00000014125
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6101593607138161926Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)686494122112380234Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)699437079125323237Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)699708426112483760Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)6100704576136029228Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 63 163 91 90 59 92 59 6 352 188 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000014125   ⟹   ENSRNOP00000014125
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6103,434,156 - 103,452,371 (-)Ensembl
mRatBN7.2 Ensembl697,701,106 - 97,719,326 (-)Ensembl
Rnor_6.0 Ensembl6102,075,632 - 102,095,201 (-)Ensembl
RefSeq Acc Id: NM_001114180   ⟹   NP_001107652
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,434,156 - 103,452,371 (-)NCBI
mRatBN7.2697,701,106 - 97,719,326 (-)NCBI
Dahl_SR_JrHsd6104,975,747 - 104,993,974 (-)NCBI
Lyon_Normotensive6104,382,715 - 104,400,942 (-)NCBI
Lyon_Hypertensive6102,176,320 - 102,194,545 (-)NCBI
F344_StmMcwi6101,331,108 - 101,349,339 (-)NCBI
Rnor_6.06102,076,736 - 102,094,951 (-)NCBI
Rnor_5.06111,450,714 - 111,468,929 (-)NCBI
RGSC_v3.46101,523,558 - 101,541,773 (-)RGD
Celera696,089,052 - 96,107,265 (-)RGD
Sequence:
RefSeq Acc Id: XM_063261929   ⟹   XP_063117999
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,435,386 - 103,452,457 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001107652 (Get FASTA)   NCBI Sequence Viewer  
  XP_063117999 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM03708 (Get FASTA)   NCBI Sequence Viewer  
  EDM03709 (Get FASTA)   NCBI Sequence Viewer  
  EDM03710 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000014125
  ENSRNOP00000014125.3
RefSeq Acc Id: NP_001107652   ⟸   NM_001114180
- UniProtKB: D4ACD5 (UniProtKB/TrEMBL),   A6HCF5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014125   ⟸   ENSRNOT00000014125
RefSeq Acc Id: XP_063117999   ⟸   XM_063261929
- Peptide Label: isoform X1
Protein Domains
DEP   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ACD5-F1-model_v2 AlphaFold D4ACD5 1-353 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305786 AgrOrtholog
BioCyc Gene G2FUF-36985 BioCyc
Ensembl Genes ENSRNOG00000010098 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014125 ENTREZGENE
  ENSRNOT00000014125.7 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro DEP_dom UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  PLEK2_DEP UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report rno:314260 UniProtKB/TrEMBL
NCBI Gene 314260 ENTREZGENE
PANTHER PLECKSTRIN UniProtKB/TrEMBL
  PLECKSTRIN-2 UniProtKB/TrEMBL
Pfam DEP UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
PhenoGen Plek2 PhenoGen
PROSITE DEP UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010098 RatGTEx
SMART DEP UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF46785 UniProtKB/TrEMBL
UniProt A6HCF5 ENTREZGENE, UniProtKB/TrEMBL
  D4ACD5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Plek2  pleckstrin 2   Plek2_predicted  pleckstrin 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Plek2_predicted  pleckstrin 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED