Desi1 (desumoylating isopeptidase 1) - Rat Genome Database

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Gene: Desi1 (desumoylating isopeptidase 1) Rattus norvegicus
Analyze
Symbol: Desi1
Name: desumoylating isopeptidase 1
RGD ID: 1305776
Description: Predicted to enable several functions, including deSUMOylase activity; importin-alpha family protein binding activity; and long-chain fatty acyl-CoA hydrolase activity. Predicted to be involved in protein desumoylation; protein export from nucleus; and regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol. Predicted to be part of protein-containing complex. Orthologous to human DESI1 (desumoylating isopeptidase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: DeSI-1; Fam152b; family with sequence similarity 152, member B; LOC315160; MGC112918; palmitoyl protein thioesterase DESI1; PPPDE peptidase domain containing 2; PPPDE peptidase domain-containing protein 2; Pppde2; RGD1305776; S-depalmitoylase DESI1; similar to D15Wsu75e protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87115,401,613 - 115,422,974 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7115,401,624 - 115,423,172 (-)EnsemblGRCr8
mRatBN7.27113,519,974 - 113,542,834 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7113,519,980 - 113,542,845 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7115,278,200 - 115,299,296 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07117,501,700 - 117,522,796 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07117,471,139 - 117,492,235 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07123,238,332 - 123,259,636 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7123,238,333 - 123,259,636 (-)Ensemblrn6Rnor6.0
Rnor_5.07123,223,022 - 123,244,325 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47120,380,505 - 120,401,688 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7109,837,407 - 109,858,663 (-)NCBICelera
RGSC_v3.17120,414,734 - 120,435,918 (-)NCBI
Cytogenetic Map7q34NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:22370726   PMID:29666234  


Genomics

Comparative Map Data
Desi1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87115,401,613 - 115,422,974 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7115,401,624 - 115,423,172 (-)EnsemblGRCr8
mRatBN7.27113,519,974 - 113,542,834 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7113,519,980 - 113,542,845 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7115,278,200 - 115,299,296 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07117,501,700 - 117,522,796 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07117,471,139 - 117,492,235 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07123,238,332 - 123,259,636 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7123,238,333 - 123,259,636 (-)Ensemblrn6Rnor6.0
Rnor_5.07123,223,022 - 123,244,325 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47120,380,505 - 120,401,688 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7109,837,407 - 109,858,663 (-)NCBICelera
RGSC_v3.17120,414,734 - 120,435,918 (-)NCBI
Cytogenetic Map7q34NCBI
DESI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382241,598,028 - 41,621,043 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2241,598,028 - 41,621,081 (-)Ensemblhg38GRCh38
GRCh372241,994,032 - 42,017,047 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,326,882 - 40,346,862 (-)NCBIBuild 36Build 36hg18NCBI36
Celera2225,803,363 - 25,823,345 (-)NCBICelera
Cytogenetic Map22q13.2NCBI
HuRef2224,959,686 - 24,982,663 (-)NCBIHuRef
CHM1_12241,954,084 - 41,977,109 (-)NCBICHM1_1
T2T-CHM13v2.02242,076,960 - 42,099,973 (-)NCBIT2T-CHM13v2.0
Desi1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391581,876,724 - 81,900,364 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1581,876,724 - 81,918,063 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381581,992,523 - 82,016,258 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1581,992,523 - 82,033,862 (-)Ensemblmm10GRCm38
MGSCv371581,822,953 - 81,846,570 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361581,819,778 - 81,843,395 (-)NCBIMGSCv36mm8
Celera1584,114,586 - 84,138,196 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.34NCBI
Desi1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541327,112,974 - 27,135,625 (-)Ensembl
ChiLan1.0NW_00495541327,115,130 - 27,135,625 (-)NCBIChiLan1.0ChiLan1.0
DESI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22351,429,384 - 51,452,296 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12254,128,670 - 54,151,715 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02222,493,114 - 22,516,191 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12240,578,968 - 40,602,094 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2240,578,968 - 40,602,094 (-)EnsemblpanPan2panpan1.1
DESI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11023,661,745 - 23,686,992 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1023,661,745 - 23,681,331 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1023,595,110 - 23,619,803 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01024,406,997 - 24,428,815 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1024,406,972 - 24,428,687 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11024,123,610 - 24,148,472 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01024,445,205 - 24,469,982 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01024,619,135 - 24,644,003 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Desi1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049457,315,609 - 7,337,803 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936492326,032 - 346,102 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936492326,029 - 348,219 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DESI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl56,929,297 - 6,954,037 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.156,929,302 - 6,954,040 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.254,300,655 - 4,323,534 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DESI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11924,135,266 - 24,160,391 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1924,134,802 - 24,160,401 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666045101,253,993 - 101,279,242 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Desi1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247527,010,963 - 7,031,125 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247527,010,941 - 7,031,125 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Desi1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11251,735,712 - 251,758,480 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Desi1
121 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:54
Interacting mature miRNAs:55
Transcripts:ENSRNOT00000007424
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)792388565119280177Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)782111245123048330Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)773618702118618702Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7115313999136544683Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
631201Panci1Pancreas inflammation QTL 100.001pancreas integrity trait (VT:0010560)percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)773557047118557047Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)782111245123048330Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)796700404118618702Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7110725024135371468Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
10450862Kidm55Kidney mass QTL 554.9kidney mass (VT:0002707)kidney weight (CMO:0000081)772725037117725037Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
10450856Livw4Liver weight QTL 43.8liver mass (VT:0003402)liver weight (CMO:0000092)772725037117725037Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)778682549123682549Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)771621154119349044Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
D7Rat189  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr87115,406,495 - 115,406,693 (+)Marker Load Pipeline
mRatBN7.27113,526,368 - 113,526,566 (+)MAPPERmRatBN7.2
Rnor_6.07123,243,205 - 123,243,402NCBIRnor6.0
Rnor_5.07123,227,894 - 123,228,091UniSTSRnor5.0
RGSC_v3.47120,385,378 - 120,385,575UniSTSRGSC3.4
RGSC_v3.47120,385,377 - 120,385,575RGDRGSC3.4
Celera7109,842,232 - 109,842,429UniSTS
RGSC_v3.17120,419,607 - 120,419,805RGD
FHH x ACI Map753.35UniSTS
FHH x ACI Map753.35RGD
Cytogenetic Map7q34UniSTS
AI427858  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27113,521,528 - 113,521,623 (+)MAPPERmRatBN7.2
Rnor_6.07123,238,365 - 123,238,459NCBIRnor6.0
Rnor_5.07123,223,055 - 123,223,149UniSTSRnor5.0
RGSC_v3.47120,380,538 - 120,380,632UniSTSRGSC3.4
Celera7109,837,440 - 109,837,534UniSTS
Cytogenetic Map7q34UniSTS
RH137322  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27113,521,492 - 113,521,651 (+)MAPPERmRatBN7.2
Rnor_6.07123,238,329 - 123,238,487NCBIRnor6.0
Rnor_5.07123,223,019 - 123,223,177UniSTSRnor5.0
RGSC_v3.47120,380,502 - 120,380,660UniSTSRGSC3.4
Celera7109,837,404 - 109,837,562UniSTS
RH 3.4 Map7889.2UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000007424   ⟹   ENSRNOP00000007424
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7115,402,303 - 115,422,928 (-)Ensembl
mRatBN7.2 Ensembl7113,519,980 - 113,542,816 (-)Ensembl
Rnor_6.0 Ensembl7123,238,333 - 123,259,636 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103557   ⟹   ENSRNOP00000080939
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7113,519,988 - 113,542,845 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000144218   ⟹   ENSRNOP00000100668
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7115,401,624 - 115,423,172 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000168895   ⟹   ENSRNOP00000108440
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7115,401,624 - 115,422,745 (-)Ensembl
RefSeq Acc Id: NM_001025703   ⟹   NP_001020874
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87115,401,623 - 115,422,928 (-)NCBI
mRatBN7.27113,521,496 - 113,542,801 (-)NCBI
Rnor_6.07123,238,332 - 123,259,636 (-)NCBI
Rnor_5.07123,223,022 - 123,244,325 (-)NCBI
RGSC_v3.47120,380,505 - 120,401,688 (-)RGD
Celera7109,837,407 - 109,858,663 (-)RGD
Sequence:
RefSeq Acc Id: XM_039079282   ⟹   XP_038935210
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87115,407,400 - 115,422,974 (-)NCBI
mRatBN7.27113,527,273 - 113,542,834 (-)NCBI
RefSeq Acc Id: XM_039079283   ⟹   XP_038935211
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87115,401,613 - 115,422,969 (-)NCBI
mRatBN7.27113,519,974 - 113,542,789 (-)NCBI
RefSeq Acc Id: XR_010052977
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87115,407,464 - 115,422,973 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001020874 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935210 (Get FASTA)   NCBI Sequence Viewer  
  XP_038935211 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH98857 (Get FASTA)   NCBI Sequence Viewer  
  EDM15682 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000007424
GenBank Protein Q4KM30 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001020874   ⟸   NM_001025703
- UniProtKB: Q4KM30 (UniProtKB/Swiss-Prot),   A6HT40 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000007424   ⟸   ENSRNOT00000007424
RefSeq Acc Id: XP_038935211   ⟸   XM_039079283
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038935210   ⟸   XM_039079282
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000080939   ⟸   ENSRNOT00000103557
Ensembl Acc Id: ENSRNOP00000108440   ⟸   ENSRNOT00000168895
Ensembl Acc Id: ENSRNOP00000100668   ⟸   ENSRNOT00000144218
Protein Domains
PPPDE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KM30-F1-model_v2 AlphaFold Q4KM30 1-168 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695524
Promoter ID:EPDNEW_R6048
Type:initiation region
Name:Desi1_1
Description:desumoylating isopeptidase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07123,259,649 - 123,259,709EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305776 AgrOrtholog
BioCyc Gene G2FUF-32649 BioCyc
Ensembl Genes ENSRNOG00000005577 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000007424 ENTREZGENE
Gene3D-CATH 3.90.1720.30 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7380029 IMAGE-MGC_LOAD
InterPro PPPDE_dom UniProtKB/Swiss-Prot
  PPPDE_sf UniProtKB/Swiss-Prot
KEGG Report rno:315160 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112918 IMAGE-MGC_LOAD
NCBI Gene 315160 ENTREZGENE
PANTHER DESUMOYLATING ISOPEPTIDASE 1 UniProtKB/Swiss-Prot
  PTHR12378 UniProtKB/Swiss-Prot
Pfam Peptidase_C97 UniProtKB/Swiss-Prot
PhenoGen Desi1 PhenoGen
PROSITE PPPDE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000005577 RatGTEx
SMART DUF862 UniProtKB/Swiss-Prot
UniProt A0A8L2Q380_RAT UniProtKB/TrEMBL
  A0ABK0LGQ6_RAT UniProtKB/TrEMBL
  A0ABK0M1F4_RAT UniProtKB/TrEMBL
  A6HT40 ENTREZGENE, UniProtKB/TrEMBL
  DESI1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-10 Desi1  desumoylating isopeptidase 1  Pppde2  PPPDE peptidase domain containing 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-02-23 Pppde2  PPPDE peptidase domain containing 2  Fam152b  family with sequence similarity 152, member B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Fam152b  family with sequence similarity 152, member B  RGD1305776  similar to D15Wsu75e protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1305776  similar to D15Wsu75e protein  RGD1305776_predicted  similar to D15Wsu75e protein (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1305776_predicted  similar to D15Wsu75e protein (predicted)  LOC315160_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC315160_predicted  similar to D15Wsu75e protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL