Scyl2 (SCY1 like pseudokinase 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Scyl2 (SCY1 like pseudokinase 2) Rattus norvegicus
Analyze
Symbol: Scyl2
Name: SCY1 like pseudokinase 2
RGD ID: 1305665
Description: Predicted to enable signaling receptor binding activity. Predicted to be involved in endosome to lysosome transport; pyramidal neuron development; and receptor-mediated endocytosis. Predicted to be located in Golgi apparatus; clathrin-coated vesicle; and endosome membrane. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-4. Orthologous to human SCYL2 (SCY1 like pseudokinase 2); INTERACTS WITH bisphenol A; gentamycin; 1,2-dimethylhydrazine (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical LOC314717; LOC314717; RGD1305665; SCY1-like 2; SCY1-like 2 (S. cerevisiae); SCY1-like protein 2; SCY1-like, kinase-like 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8725,951,734 - 26,004,663 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl725,945,258 - 26,004,631 (-)EnsemblGRCr8
mRatBN7.2724,064,404 - 24,117,338 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl724,064,404 - 24,117,305 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx726,058,920 - 26,111,817 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0728,221,349 - 28,274,181 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0727,998,664 - 28,051,565 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0730,291,087 - 30,344,464 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl730,291,087 - 30,344,445 (-)Ensemblrn6Rnor6.0
Rnor_5.0730,387,991 - 30,441,350 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4726,429,923 - 26,483,533 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera721,207,836 - 21,260,716 (-)NCBICelera
RGSC_v3.1726,451,520 - 26,503,820 (-)NCBI
Cytogenetic Map7q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19643732   PMID:25931508  


Genomics

Comparative Map Data
Scyl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8725,951,734 - 26,004,663 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl725,945,258 - 26,004,631 (-)EnsemblGRCr8
mRatBN7.2724,064,404 - 24,117,338 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl724,064,404 - 24,117,305 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx726,058,920 - 26,111,817 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0728,221,349 - 28,274,181 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0727,998,664 - 28,051,565 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0730,291,087 - 30,344,464 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl730,291,087 - 30,344,445 (-)Ensemblrn6Rnor6.0
Rnor_5.0730,387,991 - 30,441,350 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4726,429,923 - 26,483,533 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera721,207,836 - 21,260,716 (-)NCBICelera
RGSC_v3.1726,451,520 - 26,503,820 (-)NCBI
Cytogenetic Map7q13NCBI
SCYL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812100,267,177 - 100,341,715 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12100,266,830 - 100,341,728 (+)Ensemblhg38GRCh38
GRCh3712100,660,955 - 100,735,493 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361299,185,680 - 99,258,048 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341299,164,016 - 99,236,380NCBI
Celera12100,326,815 - 100,399,182 (+)NCBICelera
Cytogenetic Map12q23.1NCBI
HuRef1297,722,877 - 97,795,047 (+)NCBIHuRef
CHM1_112100,627,192 - 100,699,929 (+)NCBICHM1_1
T2T-CHM13v2.012100,228,403 - 100,303,144 (+)NCBIT2T-CHM13v2.0
Scyl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391089,474,582 - 89,522,179 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1089,474,583 - 89,522,147 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381089,638,720 - 89,686,317 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1089,638,721 - 89,686,285 (-)Ensemblmm10GRCm38
MGSCv371089,102,852 - 89,149,030 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361089,069,906 - 89,116,084 (-)NCBIMGSCv36mm8
Celera1091,640,299 - 91,687,002 (-)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1045.05NCBI
Scyl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540535,984,667 - 36,043,628 (+)Ensembl
ChiLan1.0NW_00495540535,984,667 - 36,043,581 (+)NCBIChiLan1.0ChiLan1.0
SCYL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210108,333,141 - 108,404,856 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112108,329,559 - 108,401,253 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01297,848,852 - 97,920,561 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112101,255,169 - 101,326,808 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12101,255,412 - 101,326,808 (+)EnsemblpanPan2panpan1.1
SCYL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11539,365,702 - 39,429,979 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1539,365,157 - 39,428,085 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1539,744,679 - 39,808,502 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01540,028,775 - 40,093,229 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1540,028,228 - 40,093,033 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11539,286,373 - 39,350,816 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01539,392,749 - 39,457,180 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01539,666,912 - 39,731,343 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Scyl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494520,492,420 - 20,554,460 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649213,501,663 - 13,564,867 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649213,502,854 - 13,564,886 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCYL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl583,813,206 - 83,878,760 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1583,813,207 - 83,878,766 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2588,004,752 - 88,052,916 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SCYL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11195,582,856 - 95,655,974 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037149,389,158 - 149,462,368 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Scyl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247507,412,869 - 7,477,965 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Scyl2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11168,702,612 - 168,745,198 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Scyl2
222 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:743
Count of miRNA genes:294
Interacting mature miRNAs:366
Transcripts:ENSRNOT00000002638
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)72154197751639954Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72380760668807606Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)72154197751639954Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)72154197735707405Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)71049882055498820Rat
61369Mcs2Mammary carcinoma susceptibility QTL 23.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72092049437412865Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71746044762460447Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)72005723265057232Rat

Markers in Region
AW529585  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2724,064,531 - 24,064,716 (+)MAPPERmRatBN7.2
Rnor_6.0730,291,215 - 30,291,399NCBIRnor6.0
Rnor_5.0730,388,119 - 30,388,303UniSTSRnor5.0
RGSC_v3.4726,430,051 - 26,430,235UniSTSRGSC3.4
Celera721,207,964 - 21,208,148UniSTS
RH 3.4 Map7128.9UniSTS
Cytogenetic Map7q13UniSTS
RH135279  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2724,065,719 - 24,065,935 (+)MAPPERmRatBN7.2
Rnor_6.0730,292,403 - 30,292,618NCBIRnor6.0
Rnor_5.0730,389,307 - 30,389,522UniSTSRnor5.0
RGSC_v3.4726,431,239 - 26,431,454UniSTSRGSC3.4
Celera721,209,152 - 21,209,367UniSTS
RH 3.4 Map7122.4UniSTS
Cytogenetic Map7q13UniSTS
RH138216  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2724,085,164 - 24,085,309 (+)MAPPERmRatBN7.2
Rnor_6.0730,311,942 - 30,312,086NCBIRnor6.0
Rnor_5.0730,408,846 - 30,408,990UniSTSRnor5.0
RGSC_v3.4726,451,394 - 26,451,538UniSTSRGSC3.4
Celera721,228,574 - 21,228,718UniSTS
RH 3.4 Map7127.1UniSTS
Cytogenetic Map7q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000002638   ⟹   ENSRNOP00000002638
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl725,951,734 - 26,004,631 (-)Ensembl
mRatBN7.2 Ensembl724,064,404 - 24,117,305 (-)Ensembl
Rnor_6.0 Ensembl730,291,087 - 30,344,426 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082016   ⟹   ENSRNOP00000069426
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl725,951,734 - 26,004,631 (-)Ensembl
mRatBN7.2 Ensembl724,064,404 - 24,117,305 (-)Ensembl
Rnor_6.0 Ensembl730,291,435 - 30,344,445 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119175   ⟹   ENSRNOP00000091677
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl725,945,258 - 26,004,631 (-)Ensembl
mRatBN7.2 Ensembl724,064,754 - 24,117,304 (-)Ensembl
RefSeq Acc Id: NM_001191780   ⟹   NP_001178709
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8725,951,734 - 26,004,631 (-)NCBI
mRatBN7.2724,064,404 - 24,117,305 (-)NCBI
Rnor_6.0730,291,087 - 30,344,426 (-)NCBI
Rnor_5.0730,387,991 - 30,441,350 (-)NCBI
Celera721,207,836 - 21,260,716 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006241241   ⟹   XP_006241303
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8725,952,081 - 26,004,663 (-)NCBI
mRatBN7.2724,064,415 - 24,117,338 (-)NCBI
Rnor_6.0730,291,087 - 30,344,464 (-)NCBI
Rnor_5.0730,387,991 - 30,441,350 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006241242   ⟹   XP_006241304
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8725,952,081 - 26,004,663 (-)NCBI
mRatBN7.2724,064,415 - 24,117,338 (-)NCBI
Rnor_6.0730,291,087 - 30,344,464 (-)NCBI
Rnor_5.0730,387,991 - 30,441,350 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594827   ⟹   XP_017450316
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8725,952,081 - 26,004,662 (-)NCBI
mRatBN7.2724,064,415 - 24,117,338 (-)NCBI
Rnor_6.0730,291,087 - 30,344,464 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063263439   ⟹   XP_063119509
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8725,952,081 - 26,004,357 (-)NCBI
RefSeq Acc Id: NP_001178709   ⟸   NM_001191780
- UniProtKB: D4A1Y0 (UniProtKB/TrEMBL),   A6IFR6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241304   ⟸   XM_006241242
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006241303   ⟸   XM_006241241
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JVC2 (UniProtKB/TrEMBL),   A6IFR6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450316   ⟸   XM_017594827
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSRNOP00000069426   ⟸   ENSRNOT00000082016
Ensembl Acc Id: ENSRNOP00000002638   ⟸   ENSRNOT00000002638
Ensembl Acc Id: ENSRNOP00000091677   ⟸   ENSRNOT00000119175
RefSeq Acc Id: XP_063119509   ⟸   XM_063263439
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JVC2 (UniProtKB/TrEMBL),   A6IFR6 (UniProtKB/TrEMBL)
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JVC2-F1-model_v2 AlphaFold A0A0G2JVC2 1-934 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695136
Promoter ID:EPDNEW_R5661
Type:initiation region
Name:Scyl2_1
Description:SCY1 like pseudokinase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0730,344,425 - 30,344,485EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305665 AgrOrtholog
BioCyc Gene G2FUF-34487 BioCyc
Ensembl Genes ENSRNOG00000024955 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002638 ENTREZGENE
  ENSRNOT00000002638.9 UniProtKB/TrEMBL
  ENSRNOT00000082016 ENTREZGENE
  ENSRNOT00000082016.3 UniProtKB/TrEMBL
  ENSRNOT00000119175 ENTREZGENE
  ENSRNOT00000119175.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  CIK-Related_Protein UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
KEGG Report rno:314717 UniProtKB/TrEMBL
NCBI Gene 314717 ENTREZGENE
PANTHER SCY1-LIKE PROTEIN 2 UniProtKB/TrEMBL
  SCY1-RELATED S/T PROTEIN KINASE-LIKE UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Scyl2 PhenoGen
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000024955 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
  Kinase_like UniProtKB/TrEMBL
UniProt A0A0G2JVC2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AFM7 ENTREZGENE, UniProtKB/TrEMBL
  A6IFR6 ENTREZGENE, UniProtKB/TrEMBL
  D4A1Y0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-01 Scyl2  SCY1 like pseudokinase 2  Scyl2  SCY1-like, kinase-like 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-30 Scyl2  SCY1-like, kinase-like 2  Scyl2  SCY1-like 2 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Scyl2  SCY1-like 2 (S. cerevisiae)   Scyl2_predicted  SCY1-like 2 (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Scyl2_predicted  SCY1-like 2 (S. cerevisiae) (predicted)  RGD1305665_predicted  hypothetical LOC314717 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1305665_predicted  hypothetical LOC314717 (predicted)  LOC314717_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC314717_predicted  hypothetical LOC314717 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL