Ctnnd1 (catenin delta 1) - Rat Genome Database

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Gene: Ctnnd1 (catenin delta 1) Rattus norvegicus
Analyze
Symbol: Ctnnd1
Name: catenin delta 1
RGD ID: 1305643
Description: Enables beta-catenin binding activity; cell adhesion molecule binding activity; and protein tyrosine kinase binding activity. Predicted to be involved in several processes, including cell-cell adhesion mediated by cadherin; negative regulation of blood vessel branching; and protein stabilization. Predicted to act upstream of or within several processes, including cell migration involved in sprouting angiogenesis; positive regulation of protein processing; and salivary gland development. Located in several cellular components, including dendritic spine; lamellipodium; and zonula adherens. Is active in several cellular components, including Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; and postsynaptic density, intracellular component. Biomarker of pulmonary hypertension. Human ortholog(s) of this gene implicated in blepharocheilodontic syndrome 2. Orthologous to human CTNND1 (catenin delta 1); PARTICIPATES IN E-cadherin signaling pathway; fibroblast growth factor signaling pathway; N-cadherin signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: catenin (cadherin associated protein), delta 1; catenin delta-1; catenin src; Catns; LOC311163; P120; p120 catenin; p120-catenin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8390,090,025 - 90,141,247 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl390,090,564 - 90,141,189 (-)EnsemblGRCr8
mRatBN7.2369,683,328 - 69,734,550 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl369,683,313 - 69,734,516 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx373,065,626 - 73,116,086 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0381,664,290 - 81,714,749 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0379,423,182 - 79,473,649 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0372,001,904 - 72,053,047 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl372,002,152 - 72,053,049 (-)Ensemblrn6Rnor6.0
Rnor_5.0378,522,817 - 78,573,692 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4367,809,603 - 67,860,287 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera369,039,896 - 69,090,199 (-)NCBICelera
RGSC_v3.1367,705,435 - 67,756,536 (-)NCBI
Cytogenetic Map3q24NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4,4'-trichlorobiphenyl  (ISO)
2,4,6-tribromophenol  (ISO)
2,6-dimethoxyphenol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
deguelin  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diethylstilbestrol  (ISO)
doxorubicin  (EXP)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
ethyl methanesulfonate  (ISO)
fenpyroximate  (ISO)
folic acid  (ISO)
folpet  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furfural  (ISO)
gallic acid  (ISO)
Goe 6976  (EXP)
GSK-J4  (ISO)
hexadecanoic acid  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
imidacloprid  (EXP)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
mangiferin  (ISO)
melatonin  (ISO)
menadione  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
Monobutylphthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-phosphocreatine  (EXP)
ochratoxin A  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
p-cresol  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenol red  (ISO)
picoxystrobin  (ISO)
pyrimidifen  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium dichromate  (ISO)
sodium fluoride  (ISO)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
tebufenpyrad  (ISO)
thifluzamide  (ISO)
trichloroethene  (EXP)
triptonide  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Differential expression of p120 catenin in glial cells of the adult rat brain. Chauvet N, etal., J Comp Neurol. 2004 Nov 1;479(1):15-29.
2. Distribution of p120 catenin during rat brain development: potential role in regulation of cadherin-mediated adhesion and actin cytoskeleton organization. Chauvet N, etal., Mol Cell Neurosci. 2003 Apr;22(4):467-86.
3. Fer kinase/FerT and adherens junction dynamics in the testis: an in vitro and in vivo study. Chen YM, etal., Biol Reprod. 2003 Aug;69(2):656-72. Epub 2003 Apr 16.
4. Catenins in the rat epididymis: their expression and regulation in adulthood and during postnatal development. DeBellefeuille S, etal., Endocrinology. 2003 Nov;144(11):5040-9. doi: 10.1210/en.2002-0139. Epub 2003 Aug 13.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. The catenin, p120ctn, is a common membrane-associated protein in various epithelial and non-epithelial cells and tissues. Golenhofen N and Drenckhahn D, Histochem Cell Biol. 2000 Aug;114(2):147-55.
8. Protein kinase C-Fyn kinase cascade mediates the oleic acid-induced disassembly of neonatal rat cardiomyocyte adherens junctions. Hsu KL, etal., Int J Biochem Cell Biol. 2009 Jul;41(7):1536-46. Epub 2009 Jan 8.
9. Reduced expression of E-cadherin and p120-catenin and elevated expression of PLC-gamma1 and PIKE are associated with aggressiveness of oral squamous cell carcinoma. Jiang Y, etal., Int J Clin Exp Pathol. 2015 Aug 1;8(8):9042-51. eCollection 2015.
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
12. Endothelial-to-mesenchymal transition in pulmonary hypertension. Ranchoux B, etal., Circulation. 2015 Mar 17;131(11):1006-18. doi: 10.1161/CIRCULATIONAHA.114.008750. Epub 2015 Jan 15.
13. GOA pipeline RGD automated data pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Distribution of adherens junction mediated by VE-cadherin complex in rat spleen sinus endothelial cells. Uehara K Cell Tissue Res. 2006 Mar;323(3):417-24. Epub 2005 Oct 22.
Additional References at PubMed
PMID:12370829   PMID:12734196   PMID:14610055   PMID:14657280   PMID:15138284   PMID:15166316   PMID:15331416   PMID:15775979   PMID:16399075   PMID:16510873   PMID:16973135   PMID:17047063  
PMID:17115030   PMID:17130295   PMID:17344476   PMID:17728463   PMID:18602475   PMID:18794329   PMID:18809680   PMID:19047464   PMID:19199708   PMID:19332538   PMID:19706605   PMID:20123964  
PMID:21521738   PMID:21718540   PMID:23990464   PMID:24046456   PMID:25468996   PMID:25931508   PMID:28051089   PMID:30995547  


Genomics

Comparative Map Data
Ctnnd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8390,090,025 - 90,141,247 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl390,090,564 - 90,141,189 (-)EnsemblGRCr8
mRatBN7.2369,683,328 - 69,734,550 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl369,683,313 - 69,734,516 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx373,065,626 - 73,116,086 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0381,664,290 - 81,714,749 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0379,423,182 - 79,473,649 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0372,001,904 - 72,053,047 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl372,002,152 - 72,053,049 (-)Ensemblrn6Rnor6.0
Rnor_5.0378,522,817 - 78,573,692 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4367,809,603 - 67,860,287 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera369,039,896 - 69,090,199 (-)NCBICelera
RGSC_v3.1367,705,435 - 67,756,536 (-)NCBI
Cytogenetic Map3q24NCBI
CTNND1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381157,761,802 - 57,819,540 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1157,753,243 - 57,819,546 (+)Ensemblhg38GRCh38
GRCh371157,529,274 - 57,587,012 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361157,285,810 - 57,343,228 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341157,285,844 - 57,343,226NCBI
Celera1154,886,498 - 54,943,699 (+)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1153,877,613 - 53,935,179 (+)NCBIHuRef
CHM1_11157,396,253 - 57,453,671 (+)NCBICHM1_1
T2T-CHM13v2.01157,712,138 - 57,769,885 (+)NCBIT2T-CHM13v2.0
Ctnnd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39284,417,440 - 84,489,321 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl284,430,415 - 84,481,109 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm39 Ensembl284,431,783 - 84,508,385 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38284,587,096 - 84,658,977 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl284,600,071 - 84,650,765 (-)Ensemblmm10GRCm38
GRCm38.p6 Ensembl284,601,439 - 84,678,041 (-)Ensemblmm10GRCm38
MGSCv37284,440,938 - 84,490,897 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36284,401,622 - 84,451,512 (-)NCBIMGSCv36mm8
Celera286,195,656 - 86,245,817 (-)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.45NCBI
Ctnnd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555112,658,858 - 2,703,958 (+)Ensembl
ChiLan1.0NW_0049555112,658,879 - 2,705,992 (+)NCBIChiLan1.0ChiLan1.0
CTNND1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2958,907,516 - 58,972,840 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11159,927,487 - 59,992,833 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01153,000,582 - 53,058,054 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11156,470,169 - 56,527,593 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1156,470,174 - 56,527,593 (+)EnsemblpanPan2panpan1.1
ZDHHC5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11838,497,649 - 38,522,728 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1838,497,657 - 38,517,964 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1838,044,617 - 38,064,569 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01839,179,500 - 39,205,068 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1839,179,502 - 39,204,257 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11838,762,693 - 38,782,852 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01838,335,858 - 38,355,787 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01838,966,391 - 38,986,607 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ctnnd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494714,638,778 - 14,688,432 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365814,750,947 - 4,802,289 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365814,750,845 - 4,802,262 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTNND1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl213,154,338 - 13,209,250 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1213,143,604 - 13,209,251 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2212,789,450 - 12,842,242 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CTNND1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1115,408,581 - 15,466,457 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl115,411,454 - 15,466,456 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666038112,759,621 - 112,817,271 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ctnnd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248642,951,556 - 3,006,529 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248642,953,357 - 3,000,355 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ctnnd1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1561,982,929 - 62,033,046 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ctnnd1
338 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:430
Count of miRNA genes:227
Interacting mature miRNAs:279
Transcripts:ENSRNOT00000064009
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)351490129111359995Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)373592611110333156Rat
1358293Bw38Body weight QTL 3860.0000031body mass (VT:0001259)body weight (CMO:0000012)374364268119364268Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)35365182698651826Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)34887661993876619Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)34887661993876619Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)33540319997383526Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
631832Sach1Saccharin preference QTL 12.70.02consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)34790417292904172Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)385062224136118980Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35109256196092561Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)385062224136118980Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)34865774493657744Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)358925062103925062Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)370311536115311536Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)381541464126563126Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)34865774493657744Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)35076614595766145Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)35109256196092561Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)336721849110333156Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)35076614595766145Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)34865774493657744Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)34865774493657744Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)34865774493657744Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat

Markers in Region
UniSTS:532273  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2369,683,575 - 69,684,544 (+)MAPPERmRatBN7.2
Rnor_6.0372,002,153 - 72,003,121NCBIRnor6.0
Rnor_5.0378,522,675 - 78,523,643UniSTSRnor5.0
Celera369,039,605 - 69,040,573UniSTS
Cytogenetic Map3q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000064009   ⟹   ENSRNOP00000063519
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl390,090,564 - 90,141,189 (-)Ensembl
mRatBN7.2 Ensembl369,683,313 - 69,734,498 (-)Ensembl
Rnor_6.0 Ensembl372,002,444 - 72,052,990 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081400   ⟹   ENSRNOP00000070326
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl390,090,564 - 90,141,189 (-)Ensembl
mRatBN7.2 Ensembl369,683,313 - 69,734,498 (-)Ensembl
Rnor_6.0 Ensembl372,002,152 - 72,053,049 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097596   ⟹   ENSRNOP00000082894
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl390,090,564 - 90,141,189 (-)Ensembl
mRatBN7.2 Ensembl369,683,329 - 69,734,516 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000159561   ⟹   ENSRNOP00000106367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl390,090,564 - 90,140,824 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000164039   ⟹   ENSRNOP00000104464
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl390,092,124 - 90,141,189 (-)Ensembl
RefSeq Acc Id: NM_001107740   ⟹   NP_001101210
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,564 - 90,141,189 (-)NCBI
mRatBN7.2369,683,867 - 69,734,498 (-)NCBI
Rnor_6.0372,002,444 - 72,052,990 (-)NCBI
Rnor_5.0378,522,817 - 78,573,692 (-)NCBI
RGSC_v3.4367,809,603 - 67,860,287 (-)RGD
Celera369,039,896 - 69,090,199 (-)RGD
Sequence:
RefSeq Acc Id: XM_006234452   ⟹   XP_006234514
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,233 (-)NCBI
mRatBN7.2369,685,211 - 69,734,549 (-)NCBI
Rnor_6.0372,001,904 - 72,053,047 (-)NCBI
Rnor_5.0378,522,817 - 78,573,692 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006234453   ⟹   XP_006234515
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,683,328 - 69,734,549 (-)NCBI
Rnor_6.0372,003,840 - 72,053,047 (-)NCBI
Rnor_5.0378,522,817 - 78,573,692 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761987   ⟹   XP_008760209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,233 (-)NCBI
mRatBN7.2369,685,211 - 69,734,549 (-)NCBI
Rnor_6.0372,003,840 - 72,053,046 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039104870   ⟹   XP_038960798
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,683,328 - 69,734,549 (-)NCBI
RefSeq Acc Id: XM_039104871   ⟹   XP_038960799
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,685,211 - 69,734,549 (-)NCBI
RefSeq Acc Id: XM_039104872   ⟹   XP_038960800
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,683,328 - 69,734,550 (-)NCBI
RefSeq Acc Id: XM_039104873   ⟹   XP_038960801
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,683,328 - 69,734,550 (-)NCBI
RefSeq Acc Id: XM_039104874   ⟹   XP_038960802
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,683,328 - 69,734,549 (-)NCBI
RefSeq Acc Id: XM_039104875   ⟹   XP_038960803
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,683,328 - 69,734,549 (-)NCBI
RefSeq Acc Id: XM_039104876   ⟹   XP_038960804
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,683,328 - 69,734,549 (-)NCBI
RefSeq Acc Id: XM_039104877   ⟹   XP_038960805
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,683,328 - 69,734,550 (-)NCBI
RefSeq Acc Id: XM_039104878   ⟹   XP_038960806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,233 (-)NCBI
mRatBN7.2369,685,211 - 69,734,549 (-)NCBI
RefSeq Acc Id: XM_063283647   ⟹   XP_063139717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
RefSeq Acc Id: XM_063283648   ⟹   XP_063139718
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,232 (-)NCBI
RefSeq Acc Id: XM_063283649   ⟹   XP_063139719
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
RefSeq Acc Id: XM_063283650   ⟹   XP_063139720
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001101210 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420298 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420299 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420300 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420301 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420302 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420303 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420304 (Get FASTA)   NCBI Sequence Viewer  
  XP_006234514 (Get FASTA)   NCBI Sequence Viewer  
  XP_006234515 (Get FASTA)   NCBI Sequence Viewer  
  XP_008760209 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960798 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960799 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960800 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960801 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960802 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960803 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960804 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960805 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960806 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139717 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139718 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139719 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139720 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL79305 (Get FASTA)   NCBI Sequence Viewer  
  EDL79306 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000063519
  ENSRNOP00000063519.3
  ENSRNOP00000070326
  ENSRNOP00000070326.3
  ENSRNOP00000082894
  ENSRNOP00000082894.2
  ENSRNOP00000104464
  ENSRNOP00000104464.1
  ENSRNOP00000106367.1
RefSeq Acc Id: NP_001101210   ⟸   NM_001107740
- UniProtKB: A6HMQ5 (UniProtKB/TrEMBL),   A0A8I5ZVG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234515   ⟸   XM_006234453
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JXM1 (UniProtKB/TrEMBL),   D3ZZZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234514   ⟸   XM_006234452
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JXM1 (UniProtKB/TrEMBL),   D3ZZZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008760209   ⟸   XM_008761987
- Peptide Label: isoform X14
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070326   ⟸   ENSRNOT00000081400
Ensembl Acc Id: ENSRNOP00000063519   ⟸   ENSRNOT00000064009
RefSeq Acc Id: XP_038960801   ⟸   XM_039104873
- Peptide Label: isoform X6
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960805   ⟸   XM_039104877
- Peptide Label: isoform X12
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960800   ⟸   XM_039104872
- Peptide Label: isoform X5
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960804   ⟸   XM_039104876
- Peptide Label: isoform X11
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960803   ⟸   XM_039104875
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZVG2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960802   ⟸   XM_039104874
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038960798   ⟸   XM_039104870
- Peptide Label: isoform X2
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960806   ⟸   XM_039104878
- Peptide Label: isoform X14
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960799   ⟸   XM_039104871
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000082894   ⟸   ENSRNOT00000097596
RefSeq Acc Id: XP_063139720   ⟸   XM_063283650
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063139719   ⟸   XM_063283649
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZVG2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139717   ⟸   XM_063283647
- Peptide Label: isoform X4
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139718   ⟸   XM_063283648
- Peptide Label: isoform X9
Ensembl Acc Id: ENSRNOP00000104464   ⟸   ENSRNOT00000164039
Ensembl Acc Id: ENSRNOP00000106367   ⟸   ENSRNOT00000159561

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZZ9-F1-model_v2 AlphaFold D3ZZZ9 1-932 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692177
Promoter ID:EPDNEW_R2702
Type:initiation region
Name:Ctnnd1_1
Description:catenin delta 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0372,053,004 - 72,053,064EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305643 AgrOrtholog
BioCyc Gene G2FUF-49176 BioCyc
Ensembl Genes ENSRNOG00000030790 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064009 ENTREZGENE
  ENSRNOT00000064009.3 UniProtKB/TrEMBL
  ENSRNOT00000081400 ENTREZGENE
  ENSRNOT00000081400.3 UniProtKB/TrEMBL
  ENSRNOT00000097596 ENTREZGENE
  ENSRNOT00000097596.2 UniProtKB/TrEMBL
  ENSRNOT00000159561.1 UniProtKB/TrEMBL
  ENSRNOT00000164039 ENTREZGENE
  ENSRNOT00000164039.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Armadillo UniProtKB/TrEMBL
  Plakophilin/d_Catenin UniProtKB/TrEMBL
KEGG Report rno:311163 UniProtKB/TrEMBL
NCBI Gene 311163 ENTREZGENE
PANTHER PTHR10372 UniProtKB/TrEMBL
  PTHR10372:SF6 UniProtKB/TrEMBL
Pfam Arm UniProtKB/TrEMBL
PharmGKB CTNND1 RGD
PhenoGen Ctnnd1 PhenoGen
PROSITE ARM_REPEAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000030790 RatGTEx
SMART ARM UniProtKB/TrEMBL
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
UniProt A0A0G2JXM1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZVG2 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LIE1_RAT UniProtKB/TrEMBL
  A0ABK0LKV2_RAT UniProtKB/TrEMBL
  A6HMQ4 ENTREZGENE, UniProtKB/TrEMBL
  A6HMQ5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZZZ9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Ctnnd1  catenin delta 1  Ctnnd1  catenin (cadherin associated protein), delta 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ctnnd1  catenin (cadherin associated protein), delta 1   Ctnnd1_predicted  catenin (cadherin associated protein), delta 1 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Ctnnd1_predicted  catenin (cadherin associated protein), delta 1 (predicted)  Catns_predicted  catenin src (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Catns_predicted  catenin src (predicted)      Symbol and Name status set to approved 70820 APPROVED