Adgre5 (adhesion G protein-coupled receptor E5) - Rat Genome Database

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Gene: Adgre5 (adhesion G protein-coupled receptor E5) Rattus norvegicus
Analyze
Symbol: Adgre5
Name: adhesion G protein-coupled receptor E5
RGD ID: 1305595
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be located in external side of plasma membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in vibratory urticaria. Orthologous to several human genes including ADGRE5 (adhesion G protein-coupled receptor E5); INTERACTS WITH 2,6-dinitrotoluene; acetamide; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Cd97; CD97 antigen; CD97 molecule; LOC361383
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81941,302,687 - 41,332,183 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1941,303,213 - 41,324,641 (+)EnsemblGRCr8
mRatBN7.21924,397,972 - 24,418,648 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1924,398,689 - 24,418,638 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1931,220,029 - 31,239,746 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01931,874,441 - 31,894,158 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01934,097,269 - 34,116,993 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01924,854,981 - 24,875,712 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1924,855,299 - 24,875,137 (-)Ensemblrn6Rnor6.0
Rnor_5.01935,834,136 - 35,854,866 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41926,089,268 - 26,108,997 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1923,950,020 - 23,962,006 (+)NCBICelera
RGSC_v3.11926,094,093 - 26,113,817 (+)NCBI
Cytogenetic Map19q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
avobenzone  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cortisol  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
disulfiram  (ISO)
entinostat  (ISO)
fenamidone  (ISO)
genistein  (ISO)
gentamycin  (EXP)
graphite  (EXP)
Heptachlor epoxide  (ISO)
hydrogen peroxide  (ISO)
isotretinoin  (ISO)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methotrexate  (ISO)
nickel atom  (ISO)
okadaic acid  (ISO)
ozone  (EXP,ISO)
paracetamol  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
resveratrol  (EXP,ISO)
S-adenosyl-L-methioninate  (ISO)
S-adenosyl-L-methionine  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sulforaphane  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. CD97, but not its closely related EGF-TM7 family member EMR2, is expressed on gastric, pancreatic, and esophageal carcinomas. Aust G, etal., Am J Clin Pathol. 2002 Nov;118(5):699-707.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:19299737   PMID:19946888   PMID:20458337   PMID:21423176   PMID:24613359  


Genomics

Comparative Map Data
Adgre5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81941,302,687 - 41,332,183 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1941,303,213 - 41,324,641 (+)EnsemblGRCr8
mRatBN7.21924,397,972 - 24,418,648 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1924,398,689 - 24,418,638 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1931,220,029 - 31,239,746 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01931,874,441 - 31,894,158 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01934,097,269 - 34,116,993 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01924,854,981 - 24,875,712 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1924,855,299 - 24,875,137 (-)Ensemblrn6Rnor6.0
Rnor_5.01935,834,136 - 35,854,866 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41926,089,268 - 26,108,997 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1923,950,020 - 23,962,006 (+)NCBICelera
RGSC_v3.11926,094,093 - 26,113,817 (+)NCBI
Cytogenetic Map19q11NCBI
ADGRE5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381914,381,444 - 14,408,723 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1914,380,501 - 14,408,729 (+)Ensemblhg38GRCh38
GRCh371914,492,256 - 14,519,535 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361914,353,213 - 14,380,535 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341914,353,265 - 14,380,533NCBI
Celera1914,386,354 - 14,413,665 (+)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1914,062,556 - 14,089,635 (+)NCBIHuRef
CHM1_11914,492,109 - 14,519,545 (+)NCBICHM1_1
T2T-CHM13v2.01914,508,134 - 14,535,397 (+)NCBIT2T-CHM13v2.0
Adgre5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39884,449,874 - 84,467,812 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl884,449,880 - 84,467,955 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38883,723,245 - 83,741,311 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl883,723,251 - 83,741,326 (-)Ensemblmm10GRCm38
MGSCv37886,247,150 - 86,265,210 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36886,613,469 - 86,631,274 (-)NCBIMGSCv36mm8
Celera888,013,426 - 88,031,486 (-)NCBICelera
Cytogenetic Map8C2NCBI
cM Map840.22NCBI
Adgre5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541533,007,835 - 33,021,896 (+)Ensembl
ChiLan1.0NW_00495541533,007,959 - 33,021,896 (+)NCBIChiLan1.0ChiLan1.0
ADGRE5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22019,311,297 - 19,338,420 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11918,313,489 - 18,340,636 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01913,944,894 - 13,972,041 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11914,804,469 - 14,816,268 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1914,788,568 - 14,815,663 (+)EnsemblpanPan2panpan1.1
ADGRE5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12048,204,738 - 48,220,249 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2048,204,617 - 48,219,910 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2048,081,000 - 48,095,680 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02048,723,204 - 48,738,870 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2048,718,181 - 48,738,791 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12047,935,294 - 47,949,950 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02048,361,882 - 48,376,530 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02048,604,504 - 48,619,154 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Adgre5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118207,381,440 - 207,399,073 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366592,958,931 - 2,972,771 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366592,955,633 - 2,973,277 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADGRE5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl264,844,798 - 64,890,939 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1264,844,793 - 64,862,231 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2265,098,530 - 65,115,752 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADGRE5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1613,022,141 - 13,054,710 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl613,022,115 - 13,054,112 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660746,598,745 - 6,624,806 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adgre5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249011,550,137 - 1,562,968 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249011,550,122 - 1,563,447 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Adgre5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11716,533,458 - 16,552,722 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Adgre5
238 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:100
Count of miRNA genes:75
Interacting mature miRNAs:87
Transcripts:ENSRNOT00000006152
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)193128753251431640Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)194072709254856850Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)194072709254856850Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)194072709254856850Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)193009938347207961Rat

Markers in Region
RH130682  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21924,413,659 - 24,413,865 (-)MAPPERmRatBN7.2
Rnor_6.01924,859,764 - 24,859,968NCBIRnor6.0
Rnor_5.01935,838,918 - 35,839,122UniSTSRnor5.0
RGSC_v3.41926,104,013 - 26,104,217UniSTSRGSC3.4
Celera1923,957,020 - 23,957,224UniSTS
Cytogenetic Map19q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000006152   ⟹   ENSRNOP00000006152
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1941,303,213 - 41,323,362 (+)Ensembl
mRatBN7.2 Ensembl1924,398,689 - 24,418,638 (+)Ensembl
Rnor_6.0 Ensembl1924,855,299 - 24,875,137 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115153   ⟹   ENSRNOP00000079017
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1941,303,626 - 41,323,361 (+)Ensembl
mRatBN7.2 Ensembl1924,398,689 - 24,418,638 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117374   ⟹   ENSRNOP00000079224
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1941,311,506 - 41,323,362 (+)Ensembl
mRatBN7.2 Ensembl1924,406,783 - 24,418,638 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000135529   ⟹   ENSRNOP00000111454
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1941,303,213 - 41,324,641 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000140021   ⟹   ENSRNOP00000100930
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1941,303,624 - 41,324,641 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000154815   ⟹   ENSRNOP00000104351
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1941,303,412 - 41,324,641 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000172543   ⟹   ENSRNOP00000099945
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1941,303,624 - 41,324,641 (+)Ensembl
RefSeq Acc Id: NM_001012164   ⟹   NP_001012164
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81941,303,638 - 41,323,368 (+)NCBI
mRatBN7.21924,398,915 - 24,418,646 (+)NCBI
Rnor_6.01924,854,983 - 24,874,713 (-)NCBI
Rnor_5.01935,834,136 - 35,854,866 (-)NCBI
RGSC_v3.41926,089,268 - 26,108,997 (+)RGD
Celera1923,950,020 - 23,962,006 (+)RGD
Sequence:
RefSeq Acc Id: XM_006255278   ⟹   XP_006255340
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81941,303,326 - 41,332,183 (+)NCBI
mRatBN7.21924,398,804 - 24,418,648 (+)NCBI
Rnor_6.01924,854,981 - 24,874,824 (-)NCBI
Rnor_5.01935,834,136 - 35,854,866 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006255279   ⟹   XP_006255341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81941,303,326 - 41,332,183 (+)NCBI
mRatBN7.21924,398,804 - 24,418,648 (+)NCBI
Rnor_6.01924,854,981 - 24,874,824 (-)NCBI
Rnor_5.01935,834,136 - 35,854,866 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006255281   ⟹   XP_006255343
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81941,303,326 - 41,332,183 (+)NCBI
mRatBN7.21924,398,804 - 24,418,648 (+)NCBI
Rnor_6.01924,854,981 - 24,874,824 (-)NCBI
Rnor_5.01935,834,136 - 35,854,866 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063278114   ⟹   XP_063134184
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81941,303,326 - 41,332,183 (+)NCBI
RefSeq Acc Id: XM_063278115   ⟹   XP_063134185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81941,302,687 - 41,332,183 (+)NCBI
RefSeq Acc Id: XM_063278116   ⟹   XP_063134186
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81941,302,702 - 41,332,183 (+)NCBI
RefSeq Acc Id: NP_001012164   ⟸   NM_001012164
- Peptide Label: precursor
- UniProtKB: Q5XI36 (UniProtKB/TrEMBL),   E9PT32 (UniProtKB/TrEMBL),   A0A8I6G2Z6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255343   ⟸   XM_006255281
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZM38 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255341   ⟸   XM_006255279
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZM38 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255340   ⟸   XM_006255278
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JSI4 (UniProtKB/TrEMBL),   A0A8I5ZM38 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006152   ⟸   ENSRNOT00000006152
Ensembl Acc Id: ENSRNOP00000079017   ⟸   ENSRNOT00000115153
Ensembl Acc Id: ENSRNOP00000079224   ⟸   ENSRNOT00000117374
RefSeq Acc Id: XP_063134185   ⟸   XM_063278115
- Peptide Label: isoform X3
- UniProtKB: A0A8I6G2Z6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134186   ⟸   XM_063278116
- Peptide Label: isoform X6
- UniProtKB: A0A8I6G2Z6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134184   ⟸   XM_063278114
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZM38 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000100930   ⟸   ENSRNOT00000140021
Ensembl Acc Id: ENSRNOP00000104351   ⟸   ENSRNOT00000154815
Ensembl Acc Id: ENSRNOP00000099945   ⟸   ENSRNOT00000172543
Ensembl Acc Id: ENSRNOP00000111454   ⟸   ENSRNOT00000135529
Protein Domains
EGF-like   G-protein coupled receptors family 2 profile   GAIN-B

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JSI4-F1-model_v2 AlphaFold A0A0G2JSI4 1-903 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305595 AgrOrtholog
BioCyc Gene G2FUF-6029 BioCyc
Ensembl Genes ENSRNOG00000004489 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006152 ENTREZGENE
  ENSRNOT00000006152.9 UniProtKB/TrEMBL
  ENSRNOT00000115153 ENTREZGENE
  ENSRNOT00000115153.2 UniProtKB/TrEMBL
  ENSRNOT00000117374.2 UniProtKB/TrEMBL
  ENSRNOT00000135529 ENTREZGENE
  ENSRNOT00000135529.1 UniProtKB/TrEMBL
  ENSRNOT00000140021.1 UniProtKB/TrEMBL
  ENSRNOT00000154815.1 UniProtKB/TrEMBL
  ENSRNOT00000172543.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.220.50 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7125718 IMAGE-MGC_LOAD
InterPro EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_Ca-bd UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  GAIN_B UniProtKB/TrEMBL
  GAIN_dom_sf UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/TrEMBL
  GPCR_2_CD97 UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/TrEMBL
  GPS_dom UniProtKB/TrEMBL
  NOTCH1_EGF-like UniProtKB/TrEMBL
KEGG Report rno:361383 UniProtKB/TrEMBL
MGC_CLONE MGC:95076 IMAGE-MGC_LOAD
NCBI Gene 361383 ENTREZGENE
PANTHER ADHESION G PROTEIN-COUPLED RECEPTOR E5 UniProtKB/TrEMBL
  ADHESION G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
PhenoGen Adgre5 PhenoGen
PRINTS CD97PROTEIN UniProtKB/TrEMBL
  GPCRSECRETIN UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004489 RatGTEx
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0G2JSI4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZM38 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G2Z6 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L9C8_RAT UniProtKB/TrEMBL
  A0ABK0LEQ1_RAT UniProtKB/TrEMBL
  A0ABK0LQN7_RAT UniProtKB/TrEMBL
  A0ABK0LY89_RAT UniProtKB/TrEMBL
  E9PT32 ENTREZGENE
  Q5XI36 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary E9PT32 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-03-16 Adgre5  adhesion G protein-coupled receptor E5  Cd97  CD97 molecule  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-26 Cd97  CD97 molecule  Cd97  CD97 antigen  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Cd97  CD97 antigen  Cd97_predicted  CD97 antigen (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Cd97_predicted  CD97 antigen (predicted)      Symbol and Name status set to approved 70820 APPROVED