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Gene: Gramd1b (GRAM domain containing 1B) Rattus norvegicus

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Symbol:

Gramd1b

Name:

GRAM domain containing 1B

RGD ID:

1305443

Description:

Predicted to enable cholesterol binding activity; cholesterol transfer activity; and phospholipid binding activity. Predicted to be involved in cellular response to cholesterol; cholesterol homeostasis; and intracellular sterol transport. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane; endoplasmic reticulum-plasma membrane contact site; and plasma membrane. Orthologous to human GRAMD1B (GRAM domain containing 1B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

GRAM domain-containing protein 1B; LOC103693058; LOC300644; RGD1305443; similar to RIKEN cDNA A930008A22; uncharacterized LOC103693058

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GRAMD1B (GRAM domain containing 1B)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther
Mus musculus (house mouse):	Gramd1b (GRAM domain containing 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gramd1b (GRAM domain containing 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GRAMD1B (GRAM domain containing 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GRAMD1B (GRAM domain containing 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gramd1b (GRAM domain containing 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GRAMD1B (GRAM domain containing 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GRAMD1B (GRAM domain containing 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gramd1b (GRAM domain containing 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Gramd1b (GRAM domain containing 1B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ZNF575 (zinc finger protein 575)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Gramd1b (GRAM domain containing 1B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GRAMD1B (GRAM domain containing 1B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gramd1bb (GRAM domain containing 1Bb)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gramd1bb (GRAM domain containing 1Bb)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gramd1ba (GRAM domain containing 1Ba)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	gramd1ba (GRAM domain containing 1Ba)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG30284	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG30284	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	LAM6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|PANTHER)
Caenorhabditis elegans (roundworm):	ZC328.3	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	GramD1B	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	LAM5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	LAM5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	gramd1b	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

Gramd1b^{Tn(sb-T2/Bart3)2.287Mcwi}

Genetic Models:

F344-Gramd1b^{Tn(sb-T2/Bart3)2.287Mcwi}

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	49,551,642 - 49,790,965 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	49,556,332 - 49,791,052 (-)	Ensembl				GRCr8
mRatBN7.2	8	40,654,492 - 40,893,869 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	40,659,182 - 40,893,925 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	46,166,864 - 46,328,739 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	44,445,439 - 44,607,322 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	42,313,034 - 42,474,910 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	44,160,634 - 44,399,110 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	44,165,367 - 44,327,551 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	61,200,537 - 61,378,124 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	43,260,379 - 43,429,258 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	40,275,090 - 40,434,254 (-)	NCBI		Celera
RGSC_v3.1	8	43,269,194 - 43,443,238 (-)	NCBI
Cytogenetic Map	8	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

intellectual disability (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

(S)-nicotine (ISO)

1,2-dichloroethane (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,4-methylenedioxymethamphetamine (EXP)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrolein (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

amitrole (EXP)

arsenite(3-) (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

Butylbenzyl phthalate (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

choline (ISO)

chromium(6+) (ISO)

coumarin (ISO)

DDE (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP,ISO)

Didecyldimethylammonium (ISO)

diethyl phthalate (ISO)

diisobutyl phthalate (ISO)

diisononyl phthalate (ISO)

disodium selenite (ISO)

ethanol (ISO)

fluoranthene (ISO)

folic acid (ISO)

fulvestrant (ISO)

hydrogen cyanide (ISO)

ivermectin (ISO)

L-methionine (ISO)

lead diacetate (ISO)

lead(0) (ISO)

mercury dichloride (EXP)

methapyrilene (ISO)

methimazole (EXP)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

N-nitrosodiethylamine (ISO)

nicotine (ISO)

okadaic acid (ISO)

organophosphorus compound (EXP)

ozone (ISO)

paracetamol (ISO)

perfluorooctanoic acid (EXP)

phenobarbital (EXP,ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

potassium cyanide (ISO)

propiconazole (EXP)

sodium arsenite (ISO)

sotorasib (ISO)

succimer (ISO)

sunitinib (ISO)

titanium dioxide (ISO)

trametinib (ISO)

triadimefon (EXP)

trichostatin A (ISO)

troglitazone (ISO)

valproic acid (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

cellular response to cholesterol (IEA,ISO)

cholesterol homeostasis (ISO)

intracellular sterol transport (IBA)

lipid transport (IEA)

lysosome to ER cholesterol transport (ISO)

sterol transport (IEA)

Cellular Component

endoplasmic reticulum (ISO)

endoplasmic reticulum membrane (IBA,IEA,ISO)

endoplasmic reticulum-plasma membrane contact site (IBA,IEA,ISO)

organelle membrane contact site (IEA)

plasma membrane (IBA,ISO)

Molecular Function

cholesterol binding (IBA,IEA,ISO)

cholesterol transfer activity (IBA,IEA,ISO)

lipid binding (IEA)

phosphatidic acid binding (ISO)

phosphatidylserine binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:19946888	PMID:30220461

Genomics

Comparative Map Data

Gramd1b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	49,551,642 - 49,790,965 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	49,556,332 - 49,791,052 (-)	Ensembl				GRCr8
mRatBN7.2	8	40,654,492 - 40,893,869 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	40,659,182 - 40,893,925 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	46,166,864 - 46,328,739 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	44,445,439 - 44,607,322 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	42,313,034 - 42,474,910 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	44,160,634 - 44,399,110 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	44,165,367 - 44,327,551 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	61,200,537 - 61,378,124 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	43,260,379 - 43,429,258 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	40,275,090 - 40,434,254 (-)	NCBI		Celera
RGSC_v3.1	8	43,269,194 - 43,443,238 (-)	NCBI
Cytogenetic Map	8	q22	NCBI

GRAMD1B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	123,358,422 - 123,627,767 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	123,358,251 - 123,627,774 (+)	Ensembl			hg38	GRCh38
GRCh37	11	123,229,130 - 123,498,475 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	122,901,738 - 122,998,728 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	11	120,555,834 - 120,652,938 (+)	NCBI		Celera
Cytogenetic Map	11	q24.1	NCBI
HuRef	11	119,338,151 - 119,434,725 (+)	NCBI		HuRef
CHM1_1	11	123,282,733 - 123,379,717 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	123,386,861 - 123,656,743 (+)	NCBI		T2T-CHM13v2.0

Gramd1b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	40,204,529 - 40,443,656 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	40,204,529 - 40,442,679 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	40,293,233 - 40,533,614 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	40,293,233 - 40,531,383 (-)	Ensembl			mm10	GRCm38
MGSCv37	9	40,105,492 - 40,263,349 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	40,048,478 - 40,206,335 (-)	NCBI		MGSCv36	mm8
Celera	9	37,535,572 - 37,693,642 (-)	NCBI		Celera
Cytogenetic Map	9	A5.1	NCBI
cM Map	9	21.42	NCBI

Gramd1b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	24,144,292 - 24,382,888 (+)	Ensembl
ChiLan1.0	NW_004955412	24,212,412 - 24,387,798 (+)	NCBI	ChiLan1.0	ChiLan1.0

GRAMD1B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	124,059,509 - 124,329,943 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	125,164,078 - 125,427,741 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	118,191,126 - 118,459,439 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	122,108,954 - 122,376,188 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	122,180,541 - 122,371,035 (+)	Ensembl			panPan2	panpan1.1

GRAMD1B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	10,809,493 - 10,982,266 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	10,814,512 - 10,976,833 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	10,865,472 - 11,032,585 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	10,759,703 - 10,927,233 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	10,759,703 - 10,996,098 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	10,863,815 - 11,031,256 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	10,794,377 - 10,961,649 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	10,840,820 - 11,008,361 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Gramd1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	104,921,976 - 105,160,552 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936542	8,036,207 - 8,076,592 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936542	7,910,789 - 8,081,653 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GRAMD1B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	50,335,062 - 50,505,129 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	9	50,259,020 - 50,507,328 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	55,641,619 - 55,795,671 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GRAMD1B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	114,746,337 - 115,023,174 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	114,822,815 - 115,023,878 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666043	11,081,049 - 11,354,900 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gramd1b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624880	1,525,448 - 1,787,054 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624880	1,520,450 - 1,703,352 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Gramd1b
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	34,894,568 - 34,996,338 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Gramd1b
1160 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	83
Count of miRNA genes:	72
Interacting mature miRNAs:	78
Transcripts:	ENSRNOT00000009685
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298065	Scl16	Serum cholesterol level QTL 16	3.8		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39752803	84752803	Rat
1357398	Slep3	Serum leptin concentration QTL 3	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	17994105	50763951	Rat
2313057	Bss76	Bone structure and strength QTL 76	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	8	39106258	91341052	Rat
2317030	Wbc5	White blood cell count QTL 5	3.21	0.005	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	8	16994642	61994642	Rat
2313067	Bss77	Bone structure and strength QTL 77	3.1	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	8	39106258	91341052	Rat
1578769	Uae31	Urinary albumin excretion QTL 31	3.3	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	39106363	103375781	Rat
2301416	Bp315	Blood pressure QTL 315		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	15952279	60952279	Rat
2317032	Ginf2	Gastrointestinal inflammation QTL 2	3.21	0.005	liver integrity trait (VT:0010547)	liver granuloma severity score (CMO:0002157)	8	12964165	57964165	Rat
11556286	Cm81	Cardiac mass QTL 81		0.01	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	39106258	84106258	Rat
2317036	Livw3	Liver weight QTL 3	2.43	0.01	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	8	12964165	57964165	Rat
12880023	Bw184	Body weight QTL 184		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	10382540	55382540	Rat
1578765	Klgr1	Kidney lesion grade QTL 1	3.3	0.0001	kidney morphology trait (VT:0002135)	organ lesion measurement (CMO:0000677)	8	39106363	103375781	Rat
61464	Niddm11	Non-insulin dependent diabetes mellitus QTL 11	3.1	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	44477926	89477926	Rat
2317051	Aia18	Adjuvant induced arthritis QTL 18	2.42		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	8	16994642	61994642	Rat
12880028	Cm103	Cardiac mass QTL 103		0.02	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	10382540	55382540	Rat
61337	Bp22	Blood pressure QTL 22	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	39106258	51589833	Rat
1578755	Pur5	Proteinuria QTL 5	3.3	0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	8	39106258	103375958	Rat
2317048	Ginf1	Gastrointestinal inflammation QTL 1	3.52	0.005	cecum mucosa thickness (VT:0010234)	enterocolitis severity score (CMO:0002138)	8	12964165	57964165	Rat
12880025	Cm102	Cardiac mass QTL 102		0.044	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	8	10382540	55382540	Rat
2313088	Bss75	Bone structure and strength QTL 75	3.1	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	8	39106258	91341052	Rat
1358896	Bp262	Blood pressure QTL 262	2.89		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	35464071	107982864	Rat
731182	Uae24	Urinary albumin excretion QTL 24	6.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	47541419	92541419	Rat
2302278	Gluco36	Glucose level QTL 36	4.2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	8	37760859	58991895	Rat
12880044	Am9	Aortic mass QTL 9		0.007	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	10382540	55382540	Rat
724514	Uae15	Urinary albumin excretion QTL 15	2.9		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	37760859	61459705	Rat
631648	Stl5	Serum triglyceride level QTL 5	4	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	35464071	71842899	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	8	39106258	84106258	Rat
737824	Hcar10	Hepatocarcinoma resistance QTL 10	2.9		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	8	49610204	68373388	Rat
631842	Inf1	Infertility severity QTL 1	4.1	0.001	seminal gland mass (VT:0010524)	seminal vesicle wet weight (CMO:0001603)	8	31543661	76543661	Rat
1359033	Bp273	Blood pressure QTL 273			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	39106258	84106258	Rat
1358906	Bp253	Blood pressure QTL 253	4	0.0004	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	49610204	94610204	Rat
61358	Bp39	Blood pressure QTL 39	2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	44447837	89447837	Rat
1358907	Cm40	Cardiac mass QTL 40	1.89		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	35464071	107982864	Rat
1598824	Memor4	Memory QTL 4	2.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	8	17993862	62252873	Rat
1331744	Bp217	Blood pressure QTL 217	3.398		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	39106258	67378345	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39106363	114525825	Rat
2313046	Bss78	Bone structure and strength QTL 78	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	8	39106258	91341052	Rat
1582254	Kidm31	Kidney mass QTL 31	3		kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	8	49245178	94245178	Rat
724540	Uae8	Urinary albumin excretion QTL 8	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	8	39106258	103375958	Rat
1358892	Kidm26	Kidney mass QTL 26	3.69		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	35464071	107982864	Rat
1359021	Bp271	Blood pressure QTL 271	1.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	34125902	55607752	Rat
1582243	Bw66	Body weight QTL 66	3.4	0.0048	body mass (VT:0001259)	body weight (CMO:0000012)	8	49245178	94245178	Rat
2302367	Slep5	Serum leptin concentration QTL 5	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	17994105	50763951	Rat
61373	Mcs4	Mammary carcinoma susceptibility QTL 4	1.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	8	44475043	89475043	Rat
70206	Alc20	Alcohol consumption QTL 20	2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	8	39106258	49610361	Rat

Markers in Region

D8Rat46

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	8	49,610,204 - 49,610,361 (+)	Marker Load Pipeline
mRatBN7.2	8	40,713,066 - 40,713,225 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	44,219,197 - 44,219,353	NCBI	Rnor6.0
Rnor_5.0	8	61,319,409 - 61,319,565	UniSTS	Rnor5.0
RGSC_v3.4	8	43,313,902 - 43,314,410	RGD	RGSC3.4
RGSC_v3.4	8	43,314,252 - 43,314,408	UniSTS	RGSC3.4
RGSC_v3.1	8	43,323,018 - 43,323,174	RGD
RH 3.4 Map	8	361.4	RGD
RH 3.4 Map	8	361.4	UniSTS
RH 2.0 Map	8	275.8	RGD
SHRSP x BN Map	8	32.27	RGD
FHH x ACI Map	8	32.5199	RGD
Cytogenetic Map	8	q22	UniSTS

BE120574

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	40,674,058 - 40,674,259 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	44,180,200 - 44,180,400	NCBI	Rnor6.0
Rnor_5.0	8	61,358,362 - 61,358,562	UniSTS	Rnor5.0
RGSC_v3.4	8	43,275,255 - 43,275,455	UniSTS	RGSC3.4
Celera	8	40,290,009 - 40,290,209	UniSTS
RH 3.4 Map	8	362.02	UniSTS
Cytogenetic Map	8	q22	UniSTS

Genetic Models

This gene Gramd1b is modified in the following models/strains:

F344-Gramd1b^{Tn(sb-T2/Bart3)2.287Mcwi}

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	13	72	199	91	90	59	93	59	6	378	199	13	179	96	94	31	30	30

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595537	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595539	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595542	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595543	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595544	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265085	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265086	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265091	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265095	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265096	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265097	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265098	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265099	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265100	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010053942	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010053943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000083939 ⟹ ENSRNOP00000068626

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	49,556,332 - 49,718,858 (-)	Ensembl
mRatBN7.2 Ensembl	8	40,659,182 - 40,821,703 (-)	Ensembl
Rnor_6.0 Ensembl	8	44,165,367 - 44,327,551 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097795 ⟹ ENSRNOP00000094998

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	49,556,332 - 49,652,814 (-)	Ensembl
mRatBN7.2 Ensembl	8	40,659,182 - 40,707,728 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000098747 ⟹ ENSRNOP00000086431

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	49,556,332 - 49,791,052 (-)	Ensembl
mRatBN7.2 Ensembl	8	40,659,182 - 40,893,704 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099621 ⟹ ENSRNOP00000088511

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	49,556,332 - 49,719,057 (-)	Ensembl
mRatBN7.2 Ensembl	8	40,659,182 - 40,893,925 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105397 ⟹ ENSRNOP00000089632

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	49,556,332 - 49,687,569 (-)	Ensembl
mRatBN7.2 Ensembl	8	40,659,182 - 40,742,717 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107338 ⟹ ENSRNOP00000093680

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	49,556,332 - 49,636,196 (-)	Ensembl
mRatBN7.2 Ensembl	8	40,659,182 - 40,772,466 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118974 ⟹ ENSRNOP00000078623

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	49,556,332 - 49,684,382 (-)	Ensembl
mRatBN7.2 Ensembl	8	40,659,182 - 40,822,924 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119190 ⟹ ENSRNOP00000084513

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	49,556,332 - 49,759,441 (-)	Ensembl
mRatBN7.2 Ensembl	8	40,659,182 - 40,683,216 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000120245 ⟹ ENSRNOP00000096470

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	49,556,332 - 49,700,809 (-)	Ensembl
mRatBN7.2 Ensembl	8	40,659,182 - 40,772,466 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000172877 ⟹ ENSRNOP00000110666

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	49,556,332 - 49,718,946 (-)	Ensembl

RefSeq Acc Id:

NM_001191616 ⟹ NP_001178545

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,556,332 - 49,718,946 (-)	NCBI
mRatBN7.2	8	40,659,182 - 40,821,791 (-)	NCBI
Rnor_6.0	8	44,165,324 - 44,327,441 (-)	NCBI
Rnor_5.0	8	61,200,537 - 61,378,124 (+)	NCBI
Celera	8	40,275,090 - 40,434,254 (-)	NCBI

Sequence:

show sequence

TGCCACGGGCCCCGGGGTAGGGAGCCGAGAGAGGGAGCCTCGAGCCAGGCTGCAGAAGGAGGGC
ACCGGGCAGCGGCCAGGGACCCCGATGCCGGCAGCCAACATGATGGAGAACCTGCAGCTGCCCG
CCCTGCAGGTGCCAGAGCCTCAGGGCGCGCCGGAGGGCAGCGCGGTGTGGTCCAGCTCGTCCAC
CCCCACGCTCCGCCGCCGGCGCTTTAAGATGCGCCGGATGAAGAACGTGCAGGAGCAGAGCCTG
GAGGCGGGGCTGGTAGCCCCGGACCTACCGGGCGTCTTGGCCCCCGGCAAGGAGTTCCTGCAAC
TGCCGTCCATTGAGATTACGCCCTCCAGCGACGAGGACACCCCGTGGTCCAACTGTTCCACACC
CAGCGCGTCCCCGCGCCGAAAACGCTTCCTGCTCCGCAAGTGGCTGAGGGTGAGGGAGCGGAAG
GAGTGCAGTGAGAGCAGCAGCCAGCAGAGCAGCCAGCAGAGCAGCCACGACGATGATTCCAGCA
GGTTCCTGAGTCCTCGAGTGCGCGAAGAAAGCACTGCCAGTAACTCCAACCGCAGCACGCCGGC
CTGCTCTCCCATCCTCCGGAAGCGGTCCCGCTCACCAACACCACAGAACCAGGACGGAGACACC
ATGGTGGAAAAGGGCTCAGATCACTCCTCGGACAAGTCCCCATCCACCCCAGAGCAGGGTGTGC
AACGCAGTTGCTCCTCACAGTCTGGTCGGAGCGGTGGTAAAAATTCCAAGAAAAGCCAGAGTTG
GTACAATGTGCTAAGCCCCACTTACAAGCAGAGAAATGAAGACTTCAGAAAGCTCTTCAAGCAA
CTCCCAGACACGGAGCGCCTCATTGTTGATTACTCTTGTGCACTCCAAAGAGACATTCTTCTTC
AGGGCCGACTCTACCTCTCAGAGAATTGGATCTGCTTCTACAGCAACATCTTCCGCTGGGAAAC
TCTGCTGACAGTCCGTTTGAAAGATATCTGCTCCATGACTAAAGAGAAAACAGCTCGCCTCATT
CCCAATGCCATCCAAGTCTGCACTGATTCAGAAAAGCACTTTTTTACTTCATTTGGAGCCCGGG
ATAGGACGTACATGATGATGTTCCGGCTCTGGCAGAATGCTCTCCTCGAAAAGCCCCTGTGCCC
CAAGGAGCTCTGGCACTTTGTCCACCAGTGCTACGGGAACGAGCTGGGTCTAACCAGTGATGAC
GAGGACTACGTGCCTCCAGACGATGACTTCAACACGATGGGCTACTGCGAGGAGATCCCCATAG
AAGAGAATGAGGTGAATGACAGCTCATCCAAAAGCAGCATAGAGACCAAGCCGGATGCCAGCCC
ACAGCTGCCCAAGAAGTCTATCACCAACAGCACACTGACATCTACGGGAAGCAGTGAAGCCCCC
GTCTCGTTTGATGGCTTGCCGTTGGAGGAAGAGGTGATGGAGGGTGACGGGTCCCTAGAGAAGG
AACTTGCCATTGACAACATCATAGGGGAGAAGATCGAGATCATGGCGCCTGTGACCTCCCCTTC
ACTAGACTTCAATGACAATGAGGATATCCCCACCGAGCTCAGTGATTCTTCAGATACCCACGAT
GAAGGAGAGGTCCAGGCCTTCTATGAGGACCTAAGTGGAAGACAGTATGTGAACGAAGTCTTCA
ACTTCAGCGTGGACAAACTCTATGACCTGCTGTTCACCACCTCACCCTTTCTGCGGGACTTCAT
GGAGCAGCGGCGCTTCTCTGATATCATCTTCCACCCATGGAAAAAGGAGGAGAATGGAAACCAG
AGTCGAGTGATTCTCTACACTATCACCCTTACTAATCCTCTGGCTCCCAAAACGGCCACTGTCA
GGGAGACACAGACCATGTACAAAGCAAGTCAGGAGAGCGAGTGCTATGTGATAGACGCCGAAGT
CCTCACCCACGATGTGCCATACCACGACTACTTCTATACCATCAATCGATACACACTCACCAGA
GTGGCCCGGAACAAGAGCAGACTCAGGGTCTCCACAGAGCTCCGCTATCGAAAACAGCCCTGGG
GGTTTGTGAAAACTTTCATCGAGAAGAACTTCTGGAGTGGACTGGAGGACTACTTCCGCCATTT
AGAGACTGAGCTAACCAAAACCGAGAGTACCTACTTGGCCGAGATACACAGACAGTCGCCCAAG
GAGAAGACCAATAAGTCCTCAGCAGTCCGGAGGAGGAAGCGTCCCCATGCCCACCTGCGGGTAC
CTCATCTGGAAGAGGTGATGAGTCCTGTCACCACCCCCACAGATGAAGATGTGGGCCACAGGAT
CAAGCACGTGGCAGGTTCCACGCAGACACGGCATATCCCGGAGGACACTCCTGATGGTTTTCAT
CTGCAAAGCGTGTCCAAGCTGCTGCTGGTTATCAGCTGTGTTCTGGTGCTGCTGGTCATCCTTA
ACATGATGCTCTTTTACAAGCTGTGGATGCTGGAATACACCACACAGACGCTCACTGCCTGGCA
GGGTCTCAGACTCCAGGAAAGGTTACCCCAGTCTCAGACAGAATGGGCCCAGCTATTAGAATCC
CAACAAAAGTACCACGACACCGAGCTCCAGAGGTGGAGGGAAATCATCAAATCCTCAGTGATGC
TCCTTGACCAGATGAAGGACTCTCTTATCAACCTTCAGAACGGTATCCGGTCCCGAGACTACAC
AGCTGAGAGCGACGAGAAGAGGAACCGCTATCACTGACAAGGCAGGACCAGGGGTGGCTACAAG
AGGCCTGTGCAATACATGTACATAGACCCTATAAATATATATAAATATATATATATACAGAATA
TAAATATATATTATA

hide sequence

RefSeq Acc Id:

XM_039081030 ⟹ XP_038936958

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,721,727 (-)	NCBI
mRatBN7.2	8	40,654,492 - 40,822,345 (-)	NCBI

RefSeq Acc Id:

XM_039081042 ⟹ XP_038936970

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,580,689 (-)	NCBI
mRatBN7.2	8	40,654,492 - 40,687,730 (-)	NCBI

RefSeq Acc Id:

XM_063265084 ⟹ XP_063121154

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,721,992 (-)	NCBI

RefSeq Acc Id:

XM_063265085 ⟹ XP_063121155

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,721,727 (-)	NCBI

RefSeq Acc Id:

XM_063265086 ⟹ XP_063121156

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,721,727 (-)	NCBI

RefSeq Acc Id:

XM_063265087 ⟹ XP_063121157

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,558,052 - 49,721,727 (-)	NCBI

RefSeq Acc Id:

XM_063265088 ⟹ XP_063121158

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,652,689 (-)	NCBI

RefSeq Acc Id:

XM_063265089 ⟹ XP_063121159

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,718,584 (-)	NCBI

RefSeq Acc Id:

XM_063265090 ⟹ XP_063121160

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,759,882 (-)	NCBI

RefSeq Acc Id:

XM_063265091 ⟹ XP_063121161

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,790,965 (-)	NCBI

RefSeq Acc Id:

XM_063265092 ⟹ XP_063121162

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,636,418 (-)	NCBI

RefSeq Acc Id:

XM_063265093 ⟹ XP_063121163

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,605,248 (-)	NCBI

RefSeq Acc Id:

XM_063265094 ⟹ XP_063121164

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,605,234 (-)	NCBI

RefSeq Acc Id:

XM_063265095 ⟹ XP_063121165

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,600,515 (-)	NCBI

RefSeq Acc Id:

XM_063265096 ⟹ XP_063121166

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,598,226 (-)	NCBI

RefSeq Acc Id:

XM_063265097 ⟹ XP_063121167

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,599,881 (-)	NCBI

RefSeq Acc Id:

XM_063265098 ⟹ XP_063121168

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,652,566 (-)	NCBI

RefSeq Acc Id:

XM_063265099 ⟹ XP_063121169

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,551,642 - 49,675,524 (-)	NCBI

RefSeq Acc Id:

XM_063265100 ⟹ XP_063121170

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,706,314 - 49,721,727 (-)	NCBI

RefSeq Acc Id:

XM_063265101 ⟹ XP_063121171

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,714,628 - 49,721,727 (-)	NCBI

RefSeq Acc Id:

XR_010053942

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,592,784 - 49,721,727 (-)	NCBI

RefSeq Acc Id:

XR_010053943

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	49,706,314 - 49,721,727 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001178545	(Get FASTA)	NCBI Sequence Viewer
	XP_038936958	(Get FASTA)	NCBI Sequence Viewer
	XP_038936970	(Get FASTA)	NCBI Sequence Viewer
	XP_063121154	(Get FASTA)	NCBI Sequence Viewer
	XP_063121155	(Get FASTA)	NCBI Sequence Viewer
	XP_063121156	(Get FASTA)	NCBI Sequence Viewer
	XP_063121157	(Get FASTA)	NCBI Sequence Viewer
	XP_063121158	(Get FASTA)	NCBI Sequence Viewer
	XP_063121159	(Get FASTA)	NCBI Sequence Viewer
	XP_063121160	(Get FASTA)	NCBI Sequence Viewer
	XP_063121161	(Get FASTA)	NCBI Sequence Viewer
	XP_063121162	(Get FASTA)	NCBI Sequence Viewer
	XP_063121163	(Get FASTA)	NCBI Sequence Viewer
	XP_063121164	(Get FASTA)	NCBI Sequence Viewer
	XP_063121165	(Get FASTA)	NCBI Sequence Viewer
	XP_063121166	(Get FASTA)	NCBI Sequence Viewer
	XP_063121167	(Get FASTA)	NCBI Sequence Viewer
	XP_063121168	(Get FASTA)	NCBI Sequence Viewer
	XP_063121169	(Get FASTA)	NCBI Sequence Viewer
	XP_063121170	(Get FASTA)	NCBI Sequence Viewer
	XP_063121171	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL95226	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000068626.2
	ENSRNOP00000078623.2
	ENSRNOP00000084513
	ENSRNOP00000084513.2
	ENSRNOP00000086431
	ENSRNOP00000086431.1
	ENSRNOP00000088511
	ENSRNOP00000088511.1
	ENSRNOP00000089632.2
	ENSRNOP00000093680
	ENSRNOP00000093680.2
	ENSRNOP00000094998
	ENSRNOP00000094998.2
	ENSRNOP00000096470.2
	ENSRNOP00000110666
	ENSRNOP00000110666.1

RefSeq Acc Id:

NP_001178545 ⟸ NM_001191616

- UniProtKB:

A0A8I5ZLB1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPAANMMENLQLPALQVPEPQGAPEGSAVWSSSSTPTLRRRRFKMRRMKNVQEQSLEAGLVAPD
LPGVLAPGKEFLQLPSIEITPSSDEDTPWSNCSTPSASPRRKRFLLRKWLRVRERKECSESSSQ
QSSQQSSHDDDSSRFLSPRVREESTASNSNRSTPACSPILRKRSRSPTPQNQDGDTMVEKGSDH
SSDKSPSTPEQGVQRSCSSQSGRSGGKNSKKSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLI
VDYSCALQRDILLQGRLYLSENWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPNAIQVCT
DSEKHFFTSFGARDRTYMMMFRLWQNALLEKPLCPKELWHFVHQCYGNELGLTSDDEDYVPPDD
DFNTMGYCEEIPIEENEVNDSSSKSSIETKPDASPQLPKKSITNSTLTSTGSSEAPVSFDGLPL
EEEVMEGDGSLEKELAIDNIIGEKIEIMAPVTSPSLDFNDNEDIPTELSDSSDTHDEGEVQAFY
EDLSGRQYVNEVFNFSVDKLYDLLFTTSPFLRDFMEQRRFSDIIFHPWKKEENGNQSRVILYTI
TLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDYFYTINRYTLTRVARNKSRL
RVSTELRYRKQPWGFVKTFIEKNFWSGLEDYFRHLETELTKTESTYLAEIHRQSPKEKTNKSSA
VRRRKRPHAHLRVPHLEEVMSPVTTPTDEDVGHRIKHVAGSTQTRHIPEDTPDGFHLQSVSKLL
LVISCVLVLLVILNMMLFYKLWMLEYTTQTLTAWQGLRLQERLPQSQTEWAQLLESQQKYHDTE
LQRWREIIKSSVMLLDQMKDSLINLQNGIRSRDYTAESDEKRNRYH

hide sequence

Ensembl Acc Id:

ENSRNOP00000068626 ⟸ ENSRNOT00000083939

RefSeq Acc Id:	XP_038936958 ⟸ XM_039081030
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6A887 (UniProtKB/TrEMBL), A0A8I5ZLB1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038936970 ⟸ XM_039081042
- Peptide Label:	isoform X12
- UniProtKB:	A0A8I5ZZR8 (UniProtKB/TrEMBL), A0A8I6GLE8 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000078623 ⟸ ENSRNOT00000118974

Ensembl Acc Id:

ENSRNOP00000086431 ⟸ ENSRNOT00000098747

Ensembl Acc Id:

ENSRNOP00000094998 ⟸ ENSRNOT00000097795

Ensembl Acc Id:

ENSRNOP00000096470 ⟸ ENSRNOT00000120245

Ensembl Acc Id:

ENSRNOP00000088511 ⟸ ENSRNOT00000099621

Ensembl Acc Id:

ENSRNOP00000093680 ⟸ ENSRNOT00000107338

Ensembl Acc Id:

ENSRNOP00000084513 ⟸ ENSRNOT00000119190

Ensembl Acc Id:

ENSRNOP00000089632 ⟸ ENSRNOT00000105397

RefSeq Acc Id:	XP_063121161 ⟸ XM_063265091
- Peptide Label:	isoform X9
- UniProtKB:	A0A8I6A3S5 (UniProtKB/TrEMBL), A0A8I6GLE8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121160 ⟸ XM_063265090
- Peptide Label:	isoform X8
- UniProtKB:	A0A8I6GLE8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121154 ⟸ XM_063265084
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZLB1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121156 ⟸ XM_063265086
- Peptide Label:	isoform X4
- UniProtKB:	D3ZYJ5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121155 ⟸ XM_063265085
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5ZLB1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121159 ⟸ XM_063265089
- Peptide Label:	isoform X7
- UniProtKB:	A0A8I6GLE8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121169 ⟸ XM_063265099
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6GLE8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121158 ⟸ XM_063265088
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6GLE8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121168 ⟸ XM_063265098
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6GLE8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121162 ⟸ XM_063265092
- Peptide Label:	isoform X10
- UniProtKB:	A0A8I6AAR1 (UniProtKB/TrEMBL), A0A8I6GLE8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121163 ⟸ XM_063265093
- Peptide Label:	isoform X11
- UniProtKB:	A0A8I6GLE8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121164 ⟸ XM_063265094
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6GLE8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121165 ⟸ XM_063265095
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6GLE8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121167 ⟸ XM_063265097
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6GLE8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121166 ⟸ XM_063265096
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6GLE8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121157 ⟸ XM_063265087
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I5ZLB1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121170 ⟸ XM_063265100
- Peptide Label:	isoform X13

RefSeq Acc Id:	XP_063121171 ⟸ XM_063265101
- Peptide Label:	isoform X14

Ensembl Acc Id:

ENSRNOP00000110666 ⟸ ENSRNOT00000172877

Protein Domains

VASt

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZYJ5-F1-model_v2	AlphaFold	D3ZYJ5	1-878	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305443	AgrOrtholog
BioCyc Gene	G2FUF-30843	BioCyc
Ensembl Genes	ENSRNOG00000053577	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000083939.3	UniProtKB/TrEMBL
	ENSRNOT00000097795	ENTREZGENE
	ENSRNOT00000097795.2	UniProtKB/TrEMBL
	ENSRNOT00000098747	ENTREZGENE
	ENSRNOT00000098747.2	UniProtKB/TrEMBL
	ENSRNOT00000099621	ENTREZGENE
	ENSRNOT00000099621.2	UniProtKB/TrEMBL
	ENSRNOT00000105397.2	UniProtKB/TrEMBL
	ENSRNOT00000107338	ENTREZGENE
	ENSRNOT00000107338.2	UniProtKB/TrEMBL
	ENSRNOT00000118974.2	UniProtKB/TrEMBL
	ENSRNOT00000119190	ENTREZGENE
	ENSRNOT00000119190.2	UniProtKB/TrEMBL
	ENSRNOT00000120245.2	UniProtKB/TrEMBL
	ENSRNOT00000172877	ENTREZGENE
	ENSRNOT00000172877.1	UniProtKB/TrEMBL
Gene3D-CATH	2.30.29.30	UniProtKB/TrEMBL
InterPro	Cholesterol_transport	UniProtKB/TrEMBL
	DUF4782	UniProtKB/TrEMBL
	GRAM	UniProtKB/TrEMBL
	PH-like_dom_sf	UniProtKB/TrEMBL
NCBI Gene	300644	ENTREZGENE
PANTHER	PROTEIN ASTER-B	UniProtKB/TrEMBL
	UNCHARACTERIZED	UniProtKB/TrEMBL
Pfam	DUF4782	UniProtKB/TrEMBL
	GRAM	UniProtKB/TrEMBL
PhenoGen	Gramd1b	PhenoGen
PROSITE	VAST	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000053577	RatGTEx
SMART	GRAM	UniProtKB/TrEMBL
UniProt	A0A8I5ZLB1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZZR8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A3S5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A887	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AAR1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AJ93_RAT	UniProtKB/TrEMBL
	A0A8I6GLE8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GM35_RAT	UniProtKB/TrEMBL
	A0ABK0LIC7_RAT	UniProtKB/TrEMBL
	D3ZYJ5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Gramd1b	GRAM domain containing 1B	LOC103693058	uncharacterized LOC103693058	Data merged from RGD:9364865	737654	PROVISIONAL
2014-08-25	LOC103693058	uncharacterized LOC103693058			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-04-30	Gramd1b	GRAM domain containing 1B	Gramd1b_predicted	GRAM domain containing 1B (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Gramd1b_predicted	GRAM domain containing 1B (predicted)	RGD1305443_predicted	similar to RIKEN cDNA A930008A22 (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1305443_predicted	similar to RIKEN cDNA A930008A22 (predicted)	LOC300644_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC300644_predicted	similar to RIKEN cDNA A930008A22 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar