Gene:	Sox17 ( Rattus norvegicus ) SRY (sex determining region Y)-box 17
Synonyms:	Sox17_predicted; SRY-box containing gene 17 ; LOC312936; SRY-box containing gene 17 (predicted);
ArrayIDs:	1378935_at; 1390041_at; rc_AA799800_at; 1392990_at; rc_AI172568_at; rc_AI235684_at; rc_AI031004_at;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: SOX17     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Sox17     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Sox17 Rat Celera Assembly 5 14400799 - 14403589     RGSC genome assembly v3.4 5 15244112 - 15246902     Cytogenetic 5 q12     genome assembly 3.1 5 15244440 - 15246899 Mus musculus Sox17 Mouse genome assembly build 36.1 1 4481009 - 4486494     Cytogenetic 1 1 A1 Homo sapiens SOX17 human genome assembly 8 55533047 - 55535484     Human genome assembly build 36.2 8 55533048 - 55535484     Cytogenetic 8 q11.23   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology transcription factor binding,  beta-catenin binding,  DNA binding (details...)
Biological Process	Gene Ontology protein destabilization,  protein stabilization,  negative regulation of Wnt receptor signaling pathway ...  (details...)
Cellular Component	Gene Ontology nucleus (details...)
External Links
Databases	DATABASE ID SOURCE SMART: HMG IPI PROSITE: HMG_BOX_2 IPI UNIPARC: UPI00002515B2 IPI KEGG Report: rno:312936 ENTREZGENE HomoloGene Group ID: 7948 ENTREZGENE Germonline: 1305371 Pfam: HMG_box IPI KEGG Pathway: 04310 ENTREZGENE InterPro: HMG_superfamily. IPI InterPro: HMG_HMG1/HMG2. IPI IPI: IPI00366553 IPI Ensembl Protein: ENSRNOP00000033962 IPI Gene3D-CATH: HMG-box IPI Entrez Gene: Sox17 ENTREZGENE UniProt: B2RZ07_RAT IPI Ensembl Genes: ENSRNOG00000027357 IPI Superfamily-SCOP: HMG-box IPI
Sequences	Nucleotide: XM_001068621 Get FASTA Search GEO Profiles Nucleotide: NM_001107902 Get FASTA Search GEO Profiles Nucleotide: CH473984 Get FASTA Search GEO Profiles Nucleotide: BC166978 Get FASTA Search GEO Profiles Nucleotide: XM_232640 Get FASTA Search GEO Profiles (View all 5 Nucleotide Accessions) Protein: EDM11595 Get FASTA Protein: AAI66978 Get FASTA Protein: NP_001101372 Get FASTA Protein: EDM11594 Get FASTA Protein: XP_232640 Get FASTA Protein: XP_001068621 Get FASTA (View all 6 Protein Accessions)
Clusters	UniGene: 7884
References
Curated References	1 references in RGD related to Sox17
Other References	1 other references at PubMed related to Sox17
Database Information
RGD ID	1305371
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 18-SEP-08: Sox17 SRY (sex determining region Y)-box 17 Sox17 SRY-box containing gene 17 APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863 30-APR-08: Sox17 SRY-box containing gene 17 Sox17_predicted SRY-box containing gene 17 (predicted) APPROVED 'predicted' is removed 2292626 12-JAN-05: Sox17_predicted SRY-box containing gene 17 (predicted) APPROVED Symbol and Name status set to approved 70820