Cnot7 (CCR4-NOT transcription complex, subunit 7) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Cnot7 (CCR4-NOT transcription complex, subunit 7) Rattus norvegicus
Analyze
Symbol: Cnot7
Name: CCR4-NOT transcription complex, subunit 7
RGD ID: 1305313
Description: Predicted to enable several functions, including piRNA binding activity; poly(A)-specific ribonuclease activity; and transcription corepressor activity. Predicted to be involved in several processes, including negative regulation of type I interferon-mediated signaling pathway; positive regulation of mRNA catabolic process; and positive regulation of viral genome replication. Predicted to act upstream of or within P-body assembly and positive regulation of RNA metabolic process. Predicted to be located in cytoplasm and nuclear speck. Predicted to be part of CCR4-NOT core complex. Predicted to be active in P-body. Biomarker of male infertility. Orthologous to human CNOT7 (CCR4-NOT transcription complex subunit 7); PARTICIPATES IN microRNA pathway; RNA degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium atom.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CCR4-NOT transcription complex subunit 7; LOC306492
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81658,478,882 - 58,498,046 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1658,478,900 - 58,498,046 (+)EnsemblGRCr8
mRatBN7.21651,775,416 - 51,794,581 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1651,775,412 - 51,794,576 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1657,105,829 - 57,124,948 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01660,494,464 - 60,513,620 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01655,739,783 - 55,758,902 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01654,899,452 - 54,918,616 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1654,899,452 - 54,918,613 (+)Ensemblrn6Rnor6.0
Rnor_5.01654,602,180 - 54,621,344 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41655,118,260 - 55,137,733 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1649,667,151 - 49,686,312 (+)NCBICelera
RGSC_v3.11655,118,338 - 55,137,808 (+)NCBI
Cytogenetic Map16q12.1NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
CCR4-NOT complex  (IEA,ISO)
cytoplasm  (IEA,ISO)
nuclear body  (IEA,ISO)
nuclear speck  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO)
P-body  (IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Human carbon catabolite repressor protein (CCR4)-associative factor 1: cloning, expression and characterization of its interaction with the B-cell translocation protein BTG1. Bogdan JA, etal., Biochem J. 1998 Dec 1;336 ( Pt 2):471-81.
2. Accumulated HSV1-TK proteins interfere with spermatogenesis through a disruption of the integrity of Sertoli-germ cell junctions. Cai LY, etal., J Reprod Dev. 2012;58(5):544-51. Epub 2012 Jun 14.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3 complexes. Wahle E and Winkler GS, Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):561-70. doi: 10.1016/j.bbagrm.2013.01.003. Epub 2013 Jan 19.
Additional References at PubMed
PMID:7791755   PMID:12477932   PMID:15769875   PMID:18625844   PMID:19276069   PMID:19558367   PMID:19605561   PMID:19716330   PMID:19946888   PMID:20065043   PMID:20133598   PMID:21278420  
PMID:21336257   PMID:23386060   PMID:25038453   PMID:30361391  


Genomics

Comparative Map Data
Cnot7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81658,478,882 - 58,498,046 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1658,478,900 - 58,498,046 (+)EnsemblGRCr8
mRatBN7.21651,775,416 - 51,794,581 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1651,775,412 - 51,794,576 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1657,105,829 - 57,124,948 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01660,494,464 - 60,513,620 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01655,739,783 - 55,758,902 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01654,899,452 - 54,918,616 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1654,899,452 - 54,918,613 (+)Ensemblrn6Rnor6.0
Rnor_5.01654,602,180 - 54,621,344 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41655,118,260 - 55,137,733 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1649,667,151 - 49,686,312 (+)NCBICelera
RGSC_v3.11655,118,338 - 55,137,808 (+)NCBI
Cytogenetic Map16q12.1NCBI
CNOT7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38817,224,966 - 17,246,857 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl817,224,966 - 17,247,726 (-)Ensemblhg38GRCh38
GRCh37817,082,475 - 17,104,366 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36817,131,111 - 17,148,758 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34817,133,391 - 17,148,758NCBI
Celera816,052,781 - 16,070,428 (-)NCBICelera
Cytogenetic Map8p22NCBI
HuRef815,631,606 - 15,649,253 (-)NCBIHuRef
CHM1_1817,288,194 - 17,305,840 (-)NCBICHM1_1
T2T-CHM13v2.0817,492,557 - 17,514,454 (-)NCBIT2T-CHM13v2.0
Cnot7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39840,945,579 - 40,968,888 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl840,945,581 - 40,968,888 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38840,492,538 - 40,515,847 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl840,492,540 - 40,515,847 (-)Ensemblmm10GRCm38
MGSCv37841,578,390 - 41,596,658 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36841,991,853 - 42,010,121 (-)NCBIMGSCv36mm8
Celera843,143,063 - 43,161,167 (-)NCBICelera
Cytogenetic Map8A4NCBI
cM Map823.89NCBI
Cnot7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955463285,228 - 306,077 (+)Ensembl
ChiLan1.0NW_004955463285,228 - 306,077 (+)NCBIChiLan1.0ChiLan1.0
CNOT7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2735,684,759 - 35,706,593 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1811,423,548 - 11,441,118 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0816,439,014 - 16,459,636 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1813,383,044 - 13,404,896 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl813,387,288 - 13,404,445 (-)EnsemblpanPan2panpan1.1
CNOT7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11640,554,214 - 40,571,841 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1640,555,565 - 40,571,720 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1641,051,677 - 41,069,314 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01642,607,899 - 42,625,509 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1642,608,835 - 42,625,516 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11640,701,212 - 40,718,848 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01641,244,469 - 41,262,106 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01641,437,882 - 41,455,554 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cnot7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494338,836,452 - 38,854,039 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365736,288,397 - 6,306,706 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365736,288,397 - 6,305,984 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNOT7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl174,933,453 - 4,950,346 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1174,934,379 - 4,950,093 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2175,327,739 - 5,343,363 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CNOT7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1815,315,816 - 15,333,492 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl815,317,349 - 15,333,466 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605226,945,476 - 26,963,200 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cnot7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476922,046,526 - 22,065,339 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476922,047,177 - 22,065,314 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cnot7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11346,959,308 - 46,978,336 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cnot7
149 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:384
Count of miRNA genes:220
Interacting mature miRNAs:281
Transcripts:ENSRNOT00000016882
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)164445512389455123Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)163692878281928782Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)164199206486992064Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
2302057Pia29Pristane induced arthritis QTL 293.60.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)162846870173468701Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164909919691442908Rat
1357403Slep4Serum leptin concentration QTL 43.91blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)163236104377361043Rat
8694453Bw172Body weight QTL 1728.330.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)163105803976058039Rat
1298529Arunc1Aerobic running capacity QTL 14exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)163439829479398294Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
6903294Stl30Serum triglyceride level QTL 302.60.0013blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)163188527176885271Rat
2293690Bss45Bone structure and strength QTL 455.130.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)164445512389455123Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161773081872536785Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)161590580260905802Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat

Markers in Region
D16Got55  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21651,777,099 - 51,777,294 (+)MAPPERmRatBN7.2
Rnor_6.01654,901,136 - 54,901,330NCBIRnor6.0
Rnor_5.01654,603,864 - 54,604,058UniSTSRnor5.0
RGSC_v3.41655,119,943 - 55,120,138RGDRGSC3.4
RGSC_v3.41655,119,944 - 55,120,138UniSTSRGSC3.4
Celera1649,668,835 - 49,669,029UniSTS
RGSC_v3.11655,120,019 - 55,120,213RGD
RH 3.4 Map16528.9UniSTS
RH 3.4 Map16528.9RGD
RH 2.0 Map16594.8RGD
Cytogenetic Map16q12.1UniSTS
RH134146  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21651,784,859 - 51,785,054 (+)MAPPERmRatBN7.2
Rnor_6.01654,908,896 - 54,909,090NCBIRnor6.0
Rnor_5.01654,611,624 - 54,611,818UniSTSRnor5.0
RGSC_v3.41655,127,615 - 55,127,809UniSTSRGSC3.4
Celera1649,676,595 - 49,676,789UniSTS
RH 3.4 Map16525.5UniSTS
Cytogenetic Map16q12.1UniSTS
RH141884  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21651,793,742 - 51,793,927 (+)MAPPERmRatBN7.2
Rnor_6.01654,917,778 - 54,917,962NCBIRnor6.0
Rnor_5.01654,620,506 - 54,620,690UniSTSRnor5.0
RGSC_v3.41655,136,898 - 55,137,082UniSTSRGSC3.4
Celera1649,685,477 - 49,685,661UniSTS
Cytogenetic Map16q12.1UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC111946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC167766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000016882   ⟹   ENSRNOP00000016882
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1658,478,900 - 58,498,046 (+)Ensembl
mRatBN7.2 Ensembl1651,775,412 - 51,794,576 (+)Ensembl
Rnor_6.0 Ensembl1654,899,452 - 54,918,613 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099744   ⟹   ENSRNOP00000092791
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1658,478,902 - 58,498,044 (+)Ensembl
mRatBN7.2 Ensembl1651,775,412 - 51,793,120 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000166465   ⟹   ENSRNOP00000106115
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1658,479,274 - 58,498,045 (+)Ensembl
RefSeq Acc Id: NM_001107313   ⟹   NP_001100783
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81658,478,882 - 58,498,043 (+)NCBI
mRatBN7.21651,775,416 - 51,794,578 (+)NCBI
Rnor_6.01654,899,452 - 54,918,613 (+)NCBI
Rnor_5.01654,602,180 - 54,621,344 (+)NCBI
RGSC_v3.41655,118,260 - 55,137,733 (+)RGD
Celera1649,667,151 - 49,686,312 (+)RGD
Sequence:
RefSeq Acc Id: XM_017600125   ⟹   XP_017455614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81658,478,948 - 58,498,046 (+)NCBI
mRatBN7.21651,775,479 - 51,794,581 (+)NCBI
Rnor_6.01654,899,479 - 54,918,616 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600126   ⟹   XP_017455615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81658,479,284 - 58,498,046 (+)NCBI
mRatBN7.21651,775,827 - 51,794,581 (+)NCBI
Rnor_6.01654,899,820 - 54,918,616 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600127   ⟹   XP_017455616
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81658,479,284 - 58,498,046 (+)NCBI
mRatBN7.21651,775,827 - 51,794,581 (+)NCBI
Rnor_6.01654,899,820 - 54,918,616 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600128   ⟹   XP_017455617
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81658,479,273 - 58,498,046 (+)NCBI
mRatBN7.21651,775,827 - 51,794,581 (+)NCBI
Rnor_6.01654,899,820 - 54,918,616 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039094534   ⟹   XP_038950462
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81658,478,948 - 58,498,046 (+)NCBI
mRatBN7.21651,775,479 - 51,794,581 (+)NCBI
RefSeq Acc Id: XM_039094537   ⟹   XP_038950465
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81658,478,948 - 58,498,046 (+)NCBI
mRatBN7.21651,775,464 - 51,794,581 (+)NCBI
RefSeq Acc Id: XM_063275431   ⟹   XP_063131501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81658,479,270 - 58,498,046 (+)NCBI
RefSeq Acc Id: XM_063275432   ⟹   XP_063131502
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81658,479,270 - 58,498,046 (+)NCBI
RefSeq Acc Id: XM_063275433   ⟹   XP_063131503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81658,479,274 - 58,498,046 (+)NCBI
RefSeq Acc Id: XM_063275434   ⟹   XP_063131504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81658,479,273 - 58,498,046 (+)NCBI
RefSeq Acc Id: NP_001100783   ⟸   NM_001107313
- UniProtKB: B3DMA5 (UniProtKB/TrEMBL),   A6JPV7 (UniProtKB/TrEMBL),   F7F9V0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455614   ⟸   XM_017600125
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017455616   ⟸   XM_017600127
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017455615   ⟸   XM_017600126
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017455617   ⟸   XM_017600128
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000016882   ⟸   ENSRNOT00000016882
RefSeq Acc Id: XP_038950465   ⟸   XM_039094537
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AEC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950462   ⟸   XM_039094534
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000092791   ⟸   ENSRNOT00000099744
RefSeq Acc Id: XP_063131502   ⟸   XM_063275432
- Peptide Label: isoform X2
- UniProtKB: A6JPV7 (UniProtKB/TrEMBL),   B3DMA5 (UniProtKB/TrEMBL),   F7F9V0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063131501   ⟸   XM_063275431
- Peptide Label: isoform X2
- UniProtKB: A6JPV7 (UniProtKB/TrEMBL),   B3DMA5 (UniProtKB/TrEMBL),   F7F9V0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063131504   ⟸   XM_063275434
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AEC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063131503   ⟸   XM_063275433
- Peptide Label: isoform X2
- UniProtKB: A6JPV7 (UniProtKB/TrEMBL),   B3DMA5 (UniProtKB/TrEMBL),   F7F9V0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000106115   ⟸   ENSRNOT00000166465

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B3DMA5-F1-model_v2 AlphaFold B3DMA5 1-285 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700123
Promoter ID:EPDNEW_R10647
Type:initiation region
Name:Cnot7_1
Description:CCR4-NOT transcription complex, subunit 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01654,899,475 - 54,899,535EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305313 AgrOrtholog
BioCyc Gene G2FUF-11243 BioCyc
Ensembl Genes ENSRNOG00000012263 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016882 ENTREZGENE
  ENSRNOT00000016882.7 UniProtKB/TrEMBL
  ENSRNOT00000099744 ENTREZGENE
  ENSRNOT00000099744.2 UniProtKB/TrEMBL
  ENSRNOT00000166465 ENTREZGENE
  ENSRNOT00000166465.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.420.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7455944 IMAGE-MGC_LOAD
InterPro CNOT7/CNOT8/Pop2 UniProtKB/TrEMBL
  PolynucTfrase_RNaseH_fold UniProtKB/TrEMBL
  RNase_CAF1 UniProtKB/TrEMBL
  RNaseH_sf UniProtKB/TrEMBL
KEGG Report rno:306492 UniProtKB/TrEMBL
MGC_CLONE MGC:187537 IMAGE-MGC_LOAD
NCBI Gene 306492 ENTREZGENE
PANTHER PTHR10797 UniProtKB/TrEMBL
Pfam CAF1 UniProtKB/TrEMBL
PhenoGen Cnot7 PhenoGen
RatGTEx ENSRNOG00000012263 RatGTEx
Superfamily-SCOP RNaseH_fold UniProtKB/TrEMBL
UniProt A0A8I6AEC4 ENTREZGENE, UniProtKB/TrEMBL
  A0ABZ3NNN6_RAT UniProtKB/TrEMBL
  A6JPV7 ENTREZGENE, UniProtKB/TrEMBL
  B3DMA5 ENTREZGENE
  F7F9V0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B3DMA5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Cnot7  CCR4-NOT transcription complex, subunit 7   Cnot7_predicted  CCR4-NOT transcription complex, subunit 7 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Cnot7_predicted  CCR4-NOT transcription complex, subunit 7 (predicted)      Symbol and Name status set to approved 70820 APPROVED