Slc66a2 (solute carrier family 66 member 2)

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Gene: Slc66a2 (solute carrier family 66 member 2) Rattus norvegicus

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Symbol:

Slc66a2

Name:

solute carrier family 66 member 2

RGD ID:

1305223

Description:

Predicted to be involved in phospholipid translocation and retrograde transport, endosome to Golgi. Predicted to be located in cytosol and membrane. Predicted to be active in endosome and trans-Golgi network. Orthologous to human SLC66A2 (solute carrier family 66 member 2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC361352; PQ loop repeat containing 1; PQ-loop repeat-containing protein 1; Pqlc1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC66A2 (solute carrier family 66 member 2)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther, PhylomeDB
Mus musculus (house mouse):	Slc66a2 (solute carrier family 66 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc66a2 (solute carrier family 66 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC66A2 (solute carrier family 66 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC66A2 (solute carrier family 66 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc66a2 (solute carrier family 66 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC66A2 (solute carrier family 66 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC66A2 (solute carrier family 66 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc66a2 (solute carrier family 66 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Slc66a2 (solute carrier family 66 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SLC66A2 (solute carrier family 66 member 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Slc66a2 (solute carrier family 66 member 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG13784	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ANY1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	ANY1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	T19A6.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	slc66a2.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	slc66a2.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	slc66a2.2	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	75,976,000 - 76,014,651 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	75,977,458 - 76,014,651 (+)	Ensembl				GRCr8
mRatBN7.2	18	73,702,472 - 73,739,678 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	73,702,564 - 73,739,676 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	18	75,805,106 - 75,842,255 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	76,474,446 - 76,511,598 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	74,319,964 - 74,357,311 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	76,768,466 - 76,805,773 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	76,770,012 - 76,805,766 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	18	72,002,639 - 72,040,511 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	77,151,194 - 77,187,603 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	18	72,366,086 - 72,401,733 (+)	NCBI		Celera
RGSC_v3.1	18	77,224,466 - 77,260,874 (+)	NCBI
Cytogenetic Map	18	q12.3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

3,3',4,4',5-pentachlorobiphenyl (ISO)

4,4'-sulfonyldiphenol (ISO)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (EXP,ISO)

all-trans-retinoic acid (ISO)

amiodarone (EXP)

amphetamine (EXP)

benzbromarone (EXP)

benzo[a]pyrene (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbamazepine (ISO)

chlorpyrifos (ISO)

choline (ISO)

ciguatoxin CTX1B (ISO)

clofibrate (EXP,ISO)

cocaine (EXP)

cyclosporin A (ISO)

dibutyl phthalate (EXP,ISO)

epoxiconazole (ISO)

flutamide (EXP)

folic acid (ISO)

FR900359 (ISO)

glafenine (EXP)

hexadecanoic acid (ISO)

L-ethionine (EXP)

L-methionine (ISO)

methoxychlor (EXP)

nefazodone (EXP)

okadaic acid (ISO)

omeprazole (EXP)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (EXP,ISO)

potassium dichromate (ISO)

propiconazole (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

phospholipid translocation (IBA)

retrograde transport, endosome to Golgi (IBA)

Cellular Component

cytosol (IEA)

endosome membrane (IBA)

membrane (IEA)

trans-Golgi network membrane (IBA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15489334

Genomics

Comparative Map Data

Slc66a2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	75,976,000 - 76,014,651 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	75,977,458 - 76,014,651 (+)	Ensembl				GRCr8
mRatBN7.2	18	73,702,472 - 73,739,678 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	73,702,564 - 73,739,676 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	18	75,805,106 - 75,842,255 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	76,474,446 - 76,511,598 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	74,319,964 - 74,357,311 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	76,768,466 - 76,805,773 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	76,770,012 - 76,805,766 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	18	72,002,639 - 72,040,511 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	77,151,194 - 77,187,603 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	18	72,366,086 - 72,401,733 (+)	NCBI		Celera
RGSC_v3.1	18	77,224,466 - 77,260,874 (+)	NCBI
Cytogenetic Map	18	q12.3	NCBI

SLC66A2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	79,902,420 - 79,951,653 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	79,902,420 - 79,951,676 (-)	Ensembl			hg38	GRCh38
GRCh37	18	77,662,420 - 77,711,653 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	75,763,475 - 75,812,605 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	18	75,763,475 - 75,812,605	NCBI
Celera	18	74,434,080 - 74,482,339 (-)	NCBI		Celera
Cytogenetic Map	18	q23	NCBI
HuRef	18	74,283,976 - 74,332,865 (-)	NCBI		HuRef
CHM1_1	18	77,656,671 - 77,706,865 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	18	80,178,398 - 80,227,221 (-)	NCBI		T2T-CHM13v2.0

Slc66a2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	80,298,458 - 80,335,940 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	80,296,507 - 80,335,940 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	18	80,255,241 - 80,292,724 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	80,253,292 - 80,292,725 (+)	Ensembl			mm10	GRCm38
MGSCv37	18	80,451,984 - 80,489,463 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	18	80,418,366 - 80,454,773 (+)	NCBI		MGSCv36	mm8
Celera	18	81,375,701 - 81,413,017 (+)	NCBI		Celera
Cytogenetic Map	18	E3	NCBI
cM Map	18	53.37	NCBI

Slc66a2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	63,035,932 - 63,073,980 (-)	Ensembl
ChiLan1.0	NW_004955402	63,035,932 - 63,073,981 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC66A2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	97,540,490 - 97,588,056 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	83,233,111 - 83,280,663 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	73,549,273 - 73,596,658 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	76,869,584 - 76,915,357 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	76,869,584 - 76,915,363 (-)	Ensembl			panPan2	panpan1.1

SLC66A2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	758,456 - 801,227 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	757,856 - 802,373 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	1,762,104 - 1,807,174 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	557,987 - 603,282 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	557,584 - 603,284 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	610,906 - 656,174 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	556,341 - 601,630 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	727,548 - 772,828 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Slc66a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	14,944,399 - 14,971,300 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936616	265,850 - 292,586 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936616	265,609 - 292,430 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC66A2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	127,894,111 - 127,952,225 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	127,894,111 - 127,952,268 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	310,240,990 - 310,300,141 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC66A2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	311,594 - 354,877 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	312,237 - 353,058 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666060	25,963,996 - 26,006,244 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc66a2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624806	439,613 - 479,191 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624806	440,001 - 479,191 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Slc66a2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	15	51,938,982 - 51,976,311 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Slc66a2
103 total Variants

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331733	Bp233	Blood pressure QTL 233	3.97196		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	25071126	83910656	Rat
12904069	Cm123	Cardiac mass QTL 123		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	33379158	78379158	Rat
1331798	Bp224	Blood pressure QTL 224	3.53873		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31610505	77371277	Rat
12904070	Cm124	Cardiac mass QTL 124		0.01	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	33379158	78379158	Rat
2303584	Gluco55	Glucose level QTL 55	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	18	50795212	86134022	Rat
12904071	Am18	Aortic mass QTL 18		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	33379158	78379158	Rat
1331730	Scl27	Serum cholesterol level QTL 27	3.826		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	18	54490801	86134022	Rat
61383	Bp47	Blood pressure QTL 47	17.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	31522783	76522783	Rat
12904067	Cm122	Cardiac mass QTL 122		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	33379158	78379158	Rat
61384	Bp48	Blood pressure QTL 48	19.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	62892257	79484461	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	23494057	85487725	Rat
1331742	Bp228	Blood pressure QTL 228	3.88752		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31610505	77371277	Rat
2301417	Bp319	Blood pressure QTL 319		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	33379158	78379158	Rat
1298072	Cia26	Collagen induced arthritis QTL 26	3.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	18	64383762	79484311	Rat
12904073	Kidm71	Kidney mass QTL 71		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	33379158	78379158	Rat
738008	Hcar14	Hepatocarcinoma resistance QTL 14	4.3		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion number (CMO:0001462)	18	57825243	85493247	Rat
631834	Sach3	Saccharin preference QTL 3	3.9	0.01	consumption behavior trait (VT:0002069)	calculated saccharin drink intake volume (CMO:0001600)	18	38575919	83575919	Rat
1331776	Bp225	Blood pressure QTL 225	2.829		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	31610505	77371277	Rat
631518	Bw11	Body weight QTL 11	2.8		body mass (VT:0001259)	body weight (CMO:0000012)	18	36121626	81121626	Rat
1641923	Colcr8	Colorectal carcinoma resistance QTL 8	3.1	0.0014	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	18	31990891	76990891	Rat
6893683	Bw110	Body weight QTL 110	2.7	0.002	body mass (VT:0001259)	body weight (CMO:0000012)	18	45620306	86134022	Rat
8694366	Abfw8	Abdominal fat weight QTL 8	6.38	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	18	48915737	86134022	Rat
7794793	Mcs34	Mammary carcinoma susceptibility QTL 34	1.54		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	18	65635567	85897775	Rat
631274	Sprol1	Serum protein level QTL 1	5.3		blood total protein amount (VT:0005567)	serum total protein level (CMO:0000661)	18	31644508	79484311	Rat
9589041	Epfw12	Epididymal fat weight QTL 12	17.08	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	18	48915737	86134022	Rat
8694432	Bw165	Body weight QTL 165	3.81	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	18	48915737	86134022	Rat
1358193	Emca2	Estrogen-induced mammary cancer QTL 2	1.6		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	18	65846447	86134022	Rat
1598832	Glom11	Glomerulus QTL 11	2.9		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	18	53266671	86134022	Rat
1331774	Bp226	Blood pressure QTL 226	4.41065		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31610505	77371277	Rat
9589816	Gluco68	Glucose level QTL 68	7.25	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	18	31990891	76990891	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19553532	85493247	Rat
1331770	Bp234	Blood pressure QTL 234	3.807		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	45620306	86134022	Rat
8694378	Bw157	Body weight QTL 157	3.59	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	18	31990891	76990891	Rat
2303571	Bw92	Body weight QTL 92	3		body mass (VT:0001259)	body weight (CMO:0000012)	18	50795212	86134022	Rat
631675	Iddm15	Insulin dependent diabetes mellitus QTL 15			urine glucose amount (VT:0001758)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	18	62892257	79484461	Rat
2301969	Bp324	Blood pressure QTL 324	4.05		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	61982204	76619168	Rat
2303120	Mamtr8	Mammary tumor resistance QTL 8		0.001	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	18	31610505	85493247	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	12066482	85493247	Rat
12880368	Bw187	Body weight QTL 187		0.045	body mass (VT:0001259)	body weight (CMO:0000012)	18	33379158	78379158	Rat
724542	Kidm2	Kidney mass QTL 2	2.6		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	18	61446853	86134022	Rat
61367	Iddm4	Insulin dependent diabetes mellitus QTL 4	2.33	0.0074	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	18	40462383	85462383	Rat
1359020	Ppulsi2	Prepulse inhibition QTL 2	2.71		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	18	54490801	76272247	Rat
9590318	Scort22	Serum corticosterone level QTL 22	7.64	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	18	31990891	76990891	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	12066482	85493247	Rat
1331754	Bp230	Blood pressure QTL 230	4.61609		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	15642280	86134022	Rat

Markers in Region

RH126471

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	73,739,359 - 73,739,601 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	76,805,455 - 76,805,696	NCBI	Rnor6.0
Rnor_5.0	18	72,002,716 - 72,002,957	UniSTS	Rnor5.0
RGSC_v3.4	18	77,187,285 - 77,187,526	UniSTS	RGSC3.4
Celera	18	72,401,415 - 72,401,656	UniSTS
Cytogenetic Map	18	q12.3	UniSTS

BE097236

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	73,722,686 - 73,722,848 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	76,788,677 - 76,788,838	NCBI	Rnor6.0
Rnor_5.0	18	72,019,481 - 72,019,642	UniSTS	Rnor5.0
RGSC_v3.4	18	77,169,904 - 77,170,065	UniSTS	RGSC3.4
Celera	18	72,384,790 - 72,384,951	UniSTS
RH 3.4 Map	18	787.0	UniSTS
Cytogenetic Map	18	q12.3	UniSTS

BE115218

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	73,719,901 - 73,720,120 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	76,785,893 - 76,786,111	NCBI	Rnor6.0
Rnor_5.0	18	72,022,208 - 72,022,426	UniSTS	Rnor5.0
RGSC_v3.4	18	77,167,120 - 77,167,338	UniSTS	RGSC3.4
Celera	18	72,382,006 - 72,382,224	UniSTS
RH 3.4 Map	18	785.0	UniSTS
Cytogenetic Map	18	q12.3	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	92	59	6	356	192	11	140	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001398665	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001398666	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006254952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006254953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277484	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC079072	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC088186	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000089389 ⟹ ENSRNOP00000074262

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	75,977,458 - 76,014,651 (+)	Ensembl
mRatBN7.2 Ensembl	18	73,703,473 - 73,739,676 (+)	Ensembl
Rnor_6.0 Ensembl	18	76,770,012 - 76,805,766 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112225 ⟹ ENSRNOP00000093969

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	75,978,490 - 76,014,649 (+)	Ensembl
mRatBN7.2 Ensembl	18	73,702,564 - 73,719,395 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114669 ⟹ ENSRNOP00000086993

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	75,977,472 - 76,014,649 (+)	Ensembl
mRatBN7.2 Ensembl	18	73,703,538 - 73,739,671 (+)	Ensembl

RefSeq Acc Id:

NM_001398665 ⟹ NP_001385594

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	75,978,459 - 76,014,651 (+)	NCBI
mRatBN7.2	18	73,703,480 - 73,739,678 (+)	NCBI

RefSeq Acc Id:

NM_001398666 ⟹ NP_001385595

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	75,977,458 - 76,014,651 (+)	NCBI
mRatBN7.2	18	73,702,479 - 73,739,678 (+)	NCBI

RefSeq Acc Id:

XM_006254952 ⟹ XP_006255014

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	75,976,000 - 76,014,651 (+)	NCBI
mRatBN7.2	18	73,703,379 - 73,739,678 (+)	NCBI
Rnor_6.0	18	76,769,292 - 76,805,773 (+)	NCBI
Rnor_5.0	18	72,002,639 - 72,040,511 (-)	NCBI

Sequence:

show sequence

TCGCTAGAGACAGGTTCACGTGGTCACTTGGCCTGAAAGCGCCTCCCCGTAGGTTTTTCCTAAT
CTGGGACACTCAGCAGAACAGAAATGAGTGCGGGCCACCTCTTCTGTCCCACCCGGTCGTGAGC
GCGCGTGCGCGCGCGTTAGGACCCAGCGGGGTAGCCGCGGGACCCTGGAGTGGGAGTGACCTCC
ATTGTGACGCCACGGGGCGGGGCTTCCTCTGGCTGGGACTGAGGGACAGAAGGACCGACTGGCG
CGGCGTGGCTGGTCCGGATGGTGGCTGACTGCGCAGGATAGCGGCAGCCATGTGGAGGTGACAG
TCAGCTTGCGGACTCAGAGAGCCCAAAGGAGGTTGGCCCAGGTGGACATCGCTGGCTGGCAGCG
CGGCCTCGGTGCTGGCGATGGAAGCGGAAGGCTTGGGTTGGCTTCTGGTCCCGTTGCACCAGCT
GGTTTCCTGGGTGGCCGCTGGGGCCATGGTCTTCGGAGGGGTGGTGCCGTACATACCCCAGTAC
AGGGACATCCGGAGGACTCAGAACGCTGACGGTTTTTCCACCCACGTGTGCCTGGTGCTATTGG
TGGCCAATATCTTACGGATACTCTTCTGGTTTGGCAGGCACTTCGAGTCGCCGCTCCTGTGGCA
AAGCATAGTCATGATCCTTACGATGCTACTGATGCTGAAGCTGTGCACCGAGGTCCGCGTGGCC
AACGAGCTGAACGTCAAGCGCCGCTCCTTCGCAGCGACAGACAGTAAGGATGAAGAACTCAGAG
TGCCCCCCAGGCGGCCCTACCTGGACTTCGACCCTCATCATTTCTGGCATTGGAGCAGCTTCGC
AGACTATGTGCAGTGTGTTCTGGCCTTCACAGGTGTGGCCGGCTACATCACCTACCTGTCCATC
GACTCGGCTCTGTTTGTGGAGACGTTGGGCTTCCTGGCAGTGCTGACGGAAGCCATGCTGGGTG
TGCCGCAGCTGTATCGGAACTATCGTCACCGCTCCACGGAGGGCATGAGCCTCAAGATGGTGCT
CATGTGGACAAGTGGGGACACCTTCAAGACAGCCTACTTCTTGCTCAACGGCGCACCTCTGCAG
TTCTCCGTCTGTGGTCTACTACAGGTCATGGTGGACCTGGCCATCCTGGGGCAGGCCTATGCCT
TTGCTCACCACCCCCAGAAGCCAGCACCCCATGCAGTGCATCCTGCCAGTGCCAAGGCGCTCTG
AGGAATCTAGGGCGGACGAGGACATGCGCGACTGACCAACCGTGGGTGCTGAGTCCCGATCCGT
GCTTCTGCACCAGGGAGCTTGGCCCTGTGTACCCCACAGGTGGGCCAGGCGTAGGCAGAGATTA
AGTTGAGCGCTGCGTCCCCCTCAGCCTTCAGGTGGGGGACTCAGGGTCAGTGGAGCTAGGGCTG
GCTCTGTGGTGTTTTCAAGATGATAGAAAAGGCAGATTGTCTTTCCTTACCTCCTCCAGAAAAA
CACTGGCCCGATCCTGAAATAGGTTCATGCCACTGAGCAAGATGGCAGGCACAGCAGGCAGTGG
AGTTCCTTCCTCTCAGCCAGCTTCCCTCAGTGAGCCTCTGCTCTCCCAGCAGAGCCTGTGGCAC
TCTGGACAGTGTGTAGTCATGGCTGCGGGTGGCTTGTCTGTCCTCAAGTTCTGCCCTGTCCTGC
CCTTGTATGCCACGGGTATGTGTACAGCACCTGGGGTGGATGGAAGCCGCTGGCCCGACACGGG
TCACACTGTATTTGGCTTCCTCTCTGAGCTCATCATGAGATTGTGTTACGCTCGGCAGCCTTGT
GCTGACCTGGCTGGCTCCTGGGTCCAGAATGTTCTAGATGCTTCTGTATAACAGTACCGTCCCT
TCTGCTGGGCAGAAGAATTTCTCCTGCACACGATGATGCCATCTACTTAGCACAACAGCTCTGA
TGGTCACGGTGGCTCACCAGATGGCCAAAGAGTCCGCACTGTGCCACCTCCAAGCTTCCCCCGG
ATATTCTAAGTGTGTGAGCGAGATTCTTGCTTACTCTCTGGCCTGTAAGATGCTTGTAAGATGT
TTATTTTTAAAAAACCGAAGGGAGATGTCGGTAGTGCTAATTACCTCCAAAATAAATGCCACCG
ATGGCAGCCCTAGCTGCTGAAATGAA

hide sequence

RefSeq Acc Id:

XM_006254953 ⟹ XP_006255015

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	75,977,433 - 76,014,651 (+)	NCBI
mRatBN7.2	18	73,702,472 - 73,739,678 (+)	NCBI
Rnor_6.0	18	76,768,466 - 76,805,773 (+)	NCBI
Rnor_5.0	18	72,002,639 - 72,040,511 (-)	NCBI

Sequence:

show sequence

TCCCCTTCACCCAGTGCTGCCTGCCATAGCTTCCTTCTGTTTATTCATCTTCCTGTTCCTTCCT
GGAGTTGAGCATTGGGTGTGTTGATTCAGGAAGTGGCTAGGGGGGCTGCGGGCTCCGCTGGAGG
ATAAGTACTTCCTGTCTTTTCCAGGCCCCTGGAAAACCAAGCTCGTTTGGAATTCATCTTAAGT
CCGGATGGTGGCTGACTGCGCAGGATAGCGGCAGCCATGTGGAGGTGACAGTCAGCTTGCGGAC
TCAGAGAGCCCAAAGGAGGTTGGCCCAGGTGGACATCGCTGGCTGGCAGCGCGGCCTCGGTGCT
GGCGATGGAAGCGGAAGGCTTGGGTTGGCTTCTGGTCCCGTTGCACCAGCTGGTTTCCTGGGTG
GCCGCTGGGGCCATGGTCTTCGGAGGGGTGGTGCCGTACATACCCCAGTACAGGGACATCCGGA
GGACTCAGAACGCTGACGGTTTTTCCACCCACGTGTGCCTGGTGCTATTGGTGGCCAATATCTT
ACGGATACTCTTCTGGTTTGGCAGGCACTTCGAGTCGCCGCTCCTGTGGCAAAGCATAGTCATG
ATCCTTACGATGCTACTGATGCTGAAGCTGTGCACCGAGGTCCGCGTGGCCAACGAGCTGAACG
TCAAGCGCCGCTCCTTCGCAGCGACAGACAGTAAGGATGAAGAACTCAGAGTGCCCCCCAGGCG
GCCCTACCTGGACTTCGACCCTCATCATTTCTGGCATTGGAGCAGCTTCGCAGACTATGTGCAG
TGTGTTCTGGCCTTCACAGGTGTGGCCGGCTACATCACCTACCTGTCCATCGACTCGGCTCTGT
TTGTGGAGACGTTGGGCTTCCTGGCAGTGCTGACGGAAGCCATGCTGGGTGTGCCGCAGCTGTA
TCGGAACTATCGTCACCGCTCCACGGAGGGCATGAGCCTCAAGATGGTGCTCATGTGGACAAGT
GGGGACACCTTCAAGACAGCCTACTTCTTGCTCAACGGCGCACCTCTGCAGTTCTCCGTCTGTG
GTCTACTACAGGTCATGGTGGACCTGGCCATCCTGGGGCAGGCCTATGCCTTTGCTCACCACCC
CCAGAAGCCAGCACCCCATGCAGTGCATCCTGCCAGTGCCAAGGCGCTCTGAGGAATCTAGGGC
GGACGAGGACATGCGCGACTGACCAACCGTGGGTGCTGAGTCCCGATCCGTGCTTCTGCACCAG
GGAGCTTGGCCCTGTGTACCCCACAGGTGGGCCAGGCGTAGGCAGAGATTAAGTTGAGCGCTGC
GTCCCCCTCAGCCTTCAGGTGGGGGACTCAGGGTCAGTGGAGCTAGGGCTGGCTCTGTGGTGTT
TTCAAGATGATAGAAAAGGCAGATTGTCTTTCCTTACCTCCTCCAGAAAAACACTGGCCCGATC
CTGAAATAGGTTCATGCCACTGAGCAAGATGGCAGGCACAGCAGGCAGTGGAGTTCCTTCCTCT
CAGCCAGCTTCCCTCAGTGAGCCTCTGCTCTCCCAGCAGAGCCTGTGGCACTCTGGACAGTGTG
TAGTCATGGCTGCGGGTGGCTTGTCTGTCCTCAAGTTCTGCCCTGTCCTGCCCTTGTATGCCAC
GGGTATGTGTACAGCACCTGGGGTGGATGGAAGCCGCTGGCCCGACACGGGTCACACTGTATTT
GGCTTCCTCTCTGAGCTCATCATGAGATTGTGTTACGCTCGGCAGCCTTGTGCTGACCTGGCTG
GCTCCTGGGTCCAGAATGTTCTAGATGCTTCTGTATAACAGTACCGTCCCTTCTGCTGGGCAGA
AGAATTTCTCCTGCACACGATGATGCCATCTACTTAGCACAACAGCTCTGATGGTCACGGTGGC
TCACCAGATGGCCAAAGAGTCCGCACTGTGCCACCTCCAAGCTTCCCCCGGATATTCTAAGTGT
GTGAGCGAGATTCTTGCTTACTCTCTGGCCTGTAAGATGCTTGTAAGATGTTTATTTTTAAAAA
ACCGAAGGGAGATGTCGGTAGTGCTAATTACCTCCAAAATAAATGCCACCGATGGCAGCCCTAG
CTGCTGAAATGAA

hide sequence

RefSeq Acc Id:

XM_017601004 ⟹ XP_017456493

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	75,977,958 - 76,014,651 (+)	NCBI
mRatBN7.2	18	73,703,204 - 73,739,678 (+)	NCBI
Rnor_6.0	18	76,768,820 - 76,805,773 (+)	NCBI

Sequence:

show sequence

GAGTTTCCTATTGTTGTCACCTCATCTGGCACCTCACTGCAAAGGTCCCTACAGACCGGTAGGG
CAGCTCGTTCTTCTGGTTCAACTTGCTCAGCCCACCAGGGTCCATCTGGGGTTAGAGTCGTACT
CGGGAATTCCTATGTTCTTTTCCTGTAAATGAGCACCCAGAGGAGGACTGACCTCACATATGGA
GGAGGCGGCTTAGCAATTGTGGCGTGCTGACGCCAGCCTGTAGTCGCCTAGGGCAGTCAGTGAG
TAGTTCAGCGCGAACTCCCAAGCTCCCATCCTTGGTAAGGGTTGCCAGCTCCTCATAGGCTTGC
TCAGAGACTTTCAAAGATCCCTGGAATCCCGGGGAGGATGGCGTCCTAGGCCTAGAGCTGGCCG
CTGTGACAGCTTTTTTCAACATCCAGTATTTCATCTTCAGCTGCTAGTGGCTCGGTCCGGATGG
TGGCTGACTGCGCAGGATAGCGGCAGCCATGTGGAGGTGACAGTCAGCTTGCGGACTCAGAGAG
CCCAAAGGAGGTTGGCCCAGGTGGACATCGCTGGCTGGCAGCGCGGCCTCGGTGCTGGCGATGG
AAGCGGAAGGCTTGGGTTGGCTTCTGGTCCCGTTGCACCAGCTGGTTTCCTGGGTGGCCGCTGG
GGCCATGGTCTTCGGAGGGGTGGTGCCGTACATACCCCAGTACAGGGACATCCGGAGGACTCAG
AACGCTGACGGTTTTTCCACCCACGTGTGCCTGGTGCTATTGGTGGCCAATATCTTACGGATAC
TCTTCTGGTTTGGCAGGCACTTCGAGTCGCCGCTCCTGTGGCAAAGCATAGTCATGATCCTTAC
GATGCTACTGATGCTGAAGCTGTGCACCGAGGTCCGCGTGGCCAACGAGCTGAACGTCAAGCGC
CGCTCCTTCGCAGCGACAGACAGTAAGGATGAAGAACTCAGAGTGCCCCCCAGGCGGCCCTACC
TGGACTTCGACCCTCATCATTTCTGGCATTGGAGCAGCTTCGCAGACTATGTGCAGTGTGTTCT
GGCCTTCACAGGTGTGGCCGGCTACATCACCTACCTGTCCATCGACTCGGCTCTGTTTGTGGAG
ACGTTGGGCTTCCTGGCAGTGCTGACGGAAGCCATGCTGGGTGTGCCGCAGCTGTATCGGAACT
ATCGTCACCGCTCCACGGAGGGCATGAGCCTCAAGATGGTGCTCATGTGGACAAGTGGGGACAC
CTTCAAGACAGCCTACTTCTTGCTCAACGGCGCACCTCTGCAGTTCTCCGTCTGTGGTCTACTA
CAGGTCATGGTGGACCTGGCCATCCTGGGGCAGGCCTATGCCTTTGCTCACCACCCCCAGAAGC
CAGCACCCCATGCAGTGCATCCTGCCAGTGCCAAGGCGCTCTGAGGAATCTAGGGCGGACGAGG
ACATGCGCGACTGACCAACCGTGGGTGCTGAGTCCCGATCCGTGCTTCTGCACCAGGGAGCTTG
GCCCTGTGTACCCCACAGGTGGGCCAGGCGTAGGCAGAGATTAAGTTGAGCGCTGCGTCCCCCT
CAGCCTTCAGGTGGGGGACTCAGGGTCAGTGGAGCTAGGGCTGGCTCTGTGGTGTTTTCAAGAT
GATAGAAAAGGCAGATTGTCTTTCCTTACCTCCTCCAGAAAAACACTGGCCCGATCCTGAAATA
GGTTCATGCCACTGAGCAAGATGGCAGGCACAGCAGGCAGTGGAGTTCCTTCCTCTCAGCCAGC
TTCCCTCAGTGAGCCTCTGCTCTCCCAGCAGAGCCTGTGGCACTCTGGACAGTGTGTAGTCATG
GCTGCGGGTGGCTTGTCTGTCCTCAAGTTCTGCCCTGTCCTGCCCTTGTATGCCACGGGTATGT
GTACAGCACCTGGGGTGGATGGAAGCCGCTGGCCCGACACGGGTCACACTGTATTTGGCTTCCT
CTCTGAGCTCATCATGAGATTGTGTTACGCTCGGCAGCCTTGTGCTGACCTGGCTGGCTCCTGG
GTCCAGAATGTTCTAGATGCTTCTGTATAACAGTACCGTCCCTTCTGCTGGGCAGAAGAATTTC
TCCTGCACACGATGATGCCATCTACTTAGCACAACAGCTCTGATGGTCACGGTGGCTCACCAGA
TGGCCAAAGAGTCCGCACTGTGCCACCTCCAAGCTTCCCCCGGATATTCTAAGTGTGTGAGCGA
GATTCTTGCTTACTCTCTGGCCTGTAAGATGCTTGTAAGATGTTTATTTTTAAAAAACCGAAGG
GAGATGTCGGTAGTGCTAATTACCTCCAAAATAAATGCCACCGATGGCAGCCCTAGCTGCTGAA
ATGAA

hide sequence

RefSeq Acc Id:

XM_063277484 ⟹ XP_063133554

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	75,977,918 - 76,014,651 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001385594	(Get FASTA)	NCBI Sequence Viewer
	NP_001385595	(Get FASTA)	NCBI Sequence Viewer
	XP_006255014	(Get FASTA)	NCBI Sequence Viewer
	XP_006255015	(Get FASTA)	NCBI Sequence Viewer
	XP_017456493	(Get FASTA)	NCBI Sequence Viewer
	XP_063133554	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH88186	(Get FASTA)	NCBI Sequence Viewer
	EDL75226	(Get FASTA)	NCBI Sequence Viewer
	EDL75227	(Get FASTA)	NCBI Sequence Viewer
	EDL75228	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000074262
	ENSRNOP00000086993
	ENSRNOP00000086993.1
GenBank Protein	Q5M880	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_006255015 ⟸ XM_006254953
- Peptide Label:	isoform X1
- UniProtKB:	Q5M880 (UniProtKB/Swiss-Prot), A6K5H2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEAEGLGWLLVPLHQLVSWVAAGAMVFGGVVPYIPQYRDIRRTQNADGFSTHVCLVLLVANILR ILFWFGRHFESPLLWQSIVMILTMLLMLKLCTEVRVANELNVKRRSFAATDSKDEELRVPPRRP YLDFDPHHFWHWSSFADYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQLYR NYRHRSTEGMSLKMVLMWTSGDTFKTAYFLLNGAPLQFSVCGLLQVMVDLAILGQAYAFAHHPQ KPAPHAVHPASAKAL hide sequence

RefSeq Acc Id:	XP_006255014 ⟸ XM_006254952
- Peptide Label:	isoform X1
- UniProtKB:	Q5M880 (UniProtKB/Swiss-Prot), A6K5H2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEAEGLGWLLVPLHQLVSWVAAGAMVFGGVVPYIPQYRDIRRTQNADGFSTHVCLVLLVANILR ILFWFGRHFESPLLWQSIVMILTMLLMLKLCTEVRVANELNVKRRSFAATDSKDEELRVPPRRP YLDFDPHHFWHWSSFADYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQLYR NYRHRSTEGMSLKMVLMWTSGDTFKTAYFLLNGAPLQFSVCGLLQVMVDLAILGQAYAFAHHPQ KPAPHAVHPASAKAL hide sequence

RefSeq Acc Id:	XP_017456493 ⟸ XM_017601004
- Peptide Label:	isoform X1
- UniProtKB:	Q5M880 (UniProtKB/Swiss-Prot), A6K5H2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEAEGLGWLLVPLHQLVSWVAAGAMVFGGVVPYIPQYRDIRRTQNADGFSTHVCLVLLVANILR ILFWFGRHFESPLLWQSIVMILTMLLMLKLCTEVRVANELNVKRRSFAATDSKDEELRVPPRRP YLDFDPHHFWHWSSFADYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQLYR NYRHRSTEGMSLKMVLMWTSGDTFKTAYFLLNGAPLQFSVCGLLQVMVDLAILGQAYAFAHHPQ KPAPHAVHPASAKAL hide sequence

Ensembl Acc Id:

ENSRNOP00000074262 ⟸ ENSRNOT00000089389

Ensembl Acc Id:

ENSRNOP00000086993 ⟸ ENSRNOT00000114669

Ensembl Acc Id:

ENSRNOP00000093969 ⟸ ENSRNOT00000112225

RefSeq Acc Id:	NP_001385595 ⟸ NM_001398666
- UniProtKB:	A0A8L2UR94 (UniProtKB/TrEMBL), A6K5H3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001385594 ⟸ NM_001398665
- UniProtKB:	A0A8L2UR94 (UniProtKB/TrEMBL), A6K5H3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133554 ⟸ XM_063277484
- Peptide Label:	isoform X2
- UniProtKB:	A0A8L2UR94 (UniProtKB/TrEMBL), A6K5H3 (UniProtKB/TrEMBL)

Protein Domains

PQ-loop

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5M880-F1-model_v2	AlphaFold	Q5M880	1-271	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700889

Promoter ID:

EPDNEW_R11412

Type:

single initiation site

Name:

Pqlc1_1

Description:

PQ loop repeat containing 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	18	76,769,999 - 76,770,059	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305223	AgrOrtholog
BioCyc Gene	G2FUF-6859	BioCyc
Ensembl Genes	ENSRNOG00000059215	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000089389	ENTREZGENE
	ENSRNOT00000114669	ENTREZGENE
	ENSRNOT00000114669.1	UniProtKB/Swiss-Prot
Gene3D-CATH	1.20.1280.290	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7121966	IMAGE-MGC_LOAD
	IMAGE:7369419	IMAGE-MGC_LOAD
InterPro	PQ-loop_rpt	UniProtKB/Swiss-Prot
	SLC66/Scramblase_ANY1	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:108854	IMAGE-MGC_LOAD
	MGC:94026	IMAGE-MGC_LOAD
NCBI Gene	361352	ENTREZGENE
PANTHER	PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN	UniProtKB/Swiss-Prot
	SOLUTE CARRIER FAMILY 66 MEMBER 2	UniProtKB/Swiss-Prot
Pfam	PQ-loop	UniProtKB/Swiss-Prot
PhenoGen	Slc66a2	PhenoGen
RatGTEx	ENSRNOG00000059215	RatGTEx
SMART	CTNS	UniProtKB/Swiss-Prot
UniProt	A0A8I6AJV0_RAT	UniProtKB/TrEMBL
	A0A8L2UR94	ENTREZGENE, UniProtKB/TrEMBL
	A6K5H2	ENTREZGENE, UniProtKB/TrEMBL
	A6K5H3	ENTREZGENE, UniProtKB/TrEMBL
	PQLC1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-08-09	Slc66a2	solute carrier family 66 member 2	Pqlc1	PQ loop repeat containing 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Pqlc1	PQ loop repeat containing 1	Pqlc1_predicted	PQ loop repeat containing 1 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Pqlc1_predicted	PQ loop repeat containing 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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