Cdk20 (cyclin-dependent kinase 20) - Rat Genome Database

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Gene: Cdk20 (cyclin-dependent kinase 20) Rattus norvegicus
Analyze
Symbol: Cdk20
Name: cyclin-dependent kinase 20
RGD ID: 1305219
Description: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cell division and regulation of cell cycle. Predicted to act upstream of or within several processes, including chordate embryonic development; embryonic organ development; and negative regulation of smoothened signaling pathway. Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human CDK20 (cyclin dependent kinase 20); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ccrk; cell cycle related kinase; cell cycle-related kinase; cell division protein kinase 20; LOC364666; MGC112893
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr817706,863 - 717,828 (-)NCBIGRCr8
mRatBN7.217701,122 - 707,869 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl17701,124 - 707,826 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx17719,783 - 726,487 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0172,262,360 - 2,269,064 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.017717,194 - 723,898 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0171,935,900 - 1,942,867 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl171,936,163 - 1,942,865 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0171,924,304 - 1,931,008 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,221,255 - 6,227,959 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1176,221,336 - 6,227,959 (-)NCBI
Celera171,806,819 - 1,813,523 (+)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdk20Ratalcohol dependence susceptibilityISOCDK20 (Homo sapiens)401851917DNA:SNP:: (rs560019) (human)RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdk20RatDevelopmental Disabilities  ISOCDK20 (Homo sapiens)8554872ClinVar Annotator: match by term: Global developmental delayClinVarPMID:25741868 and PMID:29127259
Cdk20Ratepilepsy  ISOCDK20 (Homo sapiens)8554872ClinVar Annotator: match by term: SeizureClinVarPMID:28327206
Cdk20Rathereditary breast ovarian cancer syndrome  ISOCDK20 (Homo sapiens)8554872ClinVar Annotator: match by term: Breast-ovarian cancer more ...ClinVarPMID:25741868
Cdk20Ratnephrotic syndrome  ISOCDK20 (Homo sapiens)8554872ClinVar Annotator: match by term: Nephrotic syndromeClinVarPMID:25741868 and PMID:29127259
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdk20Ratalcohol use disorder  ISOCDK20 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18438686

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdk20Rat1,2-dimethylhydrazine increases expressionISOCdk20 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of CDK20 mRNACTDPMID:22206623
Cdk20Rat17alpha-ethynylestradiol multiple interactionsISOCdk20 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CDK20 mRNACTDPMID:17942748
Cdk20Rat2,3',4,4',5-Pentachlorobiphenyl increases expressionISOCdk20 (Mus musculus)64804642 more ...CTDPMID:31388691
Cdk20Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOCdk20 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CDK20 mRNA and [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of CDK20 mRNACTDPMID:17942748 and PMID:25975270
Cdk20Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOCdk20 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of CDK20 mRNACTDPMID:21570461
Cdk20Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of CDK20 mRNACTDPMID:22298810
Cdk20Rat2,3,7,8-Tetrachlorodibenzofuran increases expressionEXP 64804642 more ...CTDPMID:32109520
Cdk20Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of CDK20 mRNACTDPMID:21346803
Cdk20Rat2-methylcholine affects expressionISOCDK20 (Homo sapiens)6480464beta-methylcholine affects the expression of CDK20 mRNACTDPMID:21179406
Cdk20Rat3,4-methylenedioxymethamphetamine decreases expressionISOCdk20 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of CDK20 mRNACTDPMID:20188158
Cdk20Rat4,4'-sulfonyldiphenol decreases expressionISOCdk20 (Mus musculus)6480464bisphenol S results in decreased expression of CDK20 mRNACTDPMID:39298647
Cdk20Rataflatoxin B1 increases expressionISOCdk20 (Mus musculus)6480464Aflatoxin B1 results in increased expression of CDK20 mRNACTDPMID:19770486
Cdk20RatAroclor 1254 increases expressionISOCDK20 (Homo sapiens)6480464Chlorodiphenyl (54% Chlorine) results in increased expression of CDK20 mRNACTDPMID:16934159
Cdk20Ratbenzo[a]pyrene increases expressionISOCdk20 (Mus musculus)6480464Benzo(a)pyrene results in increased expression of CDK20 mRNACTDPMID:22228805
Cdk20Ratbenzo[a]pyrene increases expressionISOCDK20 (Homo sapiens)6480464Benzo(a)pyrene results in increased expression of CDK20 mRNACTDPMID:20064835 and PMID:22316170
Cdk20Ratbis(2-ethylhexyl) phthalate increases expressionISOCdk20 (Mus musculus)6480464Diethylhexyl Phthalate results in increased expression of CDK20 mRNACTDPMID:34319233
Cdk20Ratbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of CDK20 mRNACTDPMID:25181051
Cdk20Ratbisphenol A increases expressionISOCdk20 (Mus musculus)6480464bisphenol A results in increased expression of CDK20 mRNACTDPMID:33221593
Cdk20Ratcarbon nanotube increases expressionISOCdk20 (Mus musculus)6480464Nanotubes and Carbon results in increased expression of CDK20 mRNACTDPMID:25620056
Cdk20Ratcholine multiple interactionsISOCdk20 (Mus musculus)6480464[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CDK20 geneCTDPMID:20938992

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Biological Process
1 to 20 of 23 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdk20Ratcell division involved_inIEAUniProtKB-KW:KW-01321600115GO_REF:0000043UniProtGO_REF:0000043
Cdk20Ratdorsal/ventral neural tube patterning acts_upstream_of_or_withinISOCdk20 (Mus musculus)1624291MGI:108075 more ...RGDPMID:28817564
Cdk20Ratembryonic brain development acts_upstream_of_or_withinISOCdk20 (Mus musculus)1624291MGI:6113512 PMID:28817564RGDPMID:28817564
Cdk20Ratembryonic brain development acts_upstream_of_or_withinIEAUniProtKB:Q9JHU3 and ensembl:ENSMUSP000000219391600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk20Ratembryonic camera-type eye development acts_upstream_of_or_withinISOCdk20 (Mus musculus)1624291MGI:6113512 PMID:28817564RGDPMID:28817564
Cdk20Ratembryonic camera-type eye development acts_upstream_of_or_withinIEAUniProtKB:Q9JHU3 and ensembl:ENSMUSP000000219391600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk20Ratembryonic skeletal system development acts_upstream_of_or_withinIEAUniProtKB:Q9JHU3 and ensembl:ENSMUSP000000219391600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk20Ratembryonic skeletal system development acts_upstream_of_or_withinISOCdk20 (Mus musculus)1624291MGI:6113512 PMID:28817564RGDPMID:28817564
Cdk20Ratfloor plate formation acts_upstream_of_or_withinISOCdk20 (Mus musculus)1624291MGI:6113512 PMID:28817564RGDPMID:28817564
Cdk20Ratfloor plate formation acts_upstream_of_or_withinIEAUniProtKB:Q9JHU3 and ensembl:ENSMUSP000000219391600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk20Ratnegative regulation of smoothened signaling pathway acts_upstream_of_or_withinISOCdk20 (Mus musculus)1624291MGI:108075 more ...RGDPMID:28817564
Cdk20Ratnegative regulation of smoothened signaling pathway acts_upstream_of_or_withinIEAUniProtKB:Q9JHU3 and ensembl:ENSMUSP000000219391600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk20Ratneural tube closure acts_upstream_of_or_withinISOCdk20 (Mus musculus)1624291MGI:6113512 PMID:28817564RGDPMID:28817564
Cdk20Ratneural tube closure acts_upstream_of_or_withinIEAUniProtKB:Q9JHU3 and ensembl:ENSMUSP000000219391600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk20Ratprotein localization to cilium acts_upstream_of_or_withinISOCdk20 (Mus musculus)1624291MGI:6113512 PMID:28817564RGDPMID:28817564
Cdk20Ratprotein localization to cilium acts_upstream_of_or_withinIEAUniProtKB:Q9JHU3 and ensembl:ENSMUSP000000219391600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk20Ratregulation of cell cycle involved_inIEAGO:00046931600115GO_REF:0000108GOCGO_REF:0000108
Cdk20Ratregulation of protein maturation acts_upstream_of_or_withinISOCdk20 (Mus musculus)1624291MGI:6113512 PMID:28817564RGDPMID:28817564
Cdk20Ratregulation of protein maturation acts_upstream_of_or_withinIEAUniProtKB:Q9JHU3 and ensembl:ENSMUSP000000219391600115GO_REF:0000107EnsemblGO_REF:0000107
Cdk20Ratregulation of smoothened signaling pathway acts_upstream_of_or_withinIEAUniProtKB:Q9JHU3 and ensembl:ENSMUSP000000219391600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
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Object Symbol
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Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdk20Ratcell projection located_inIEAUniProtKB-KW:KW-09661600115GO_REF:0000043UniProtGO_REF:0000043
Cdk20Ratcilium located_inIEAUniProtKB-SubCell:SL-00661600115GO_REF:0000044UniProtGO_REF:0000044
Cdk20Ratcilium located_inIEAUniProtKB-KW:KW-09691600115GO_REF:0000043UniProtGO_REF:0000043
Cdk20Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Cdk20Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Cdk20RatGolgi apparatus located_inISOCDK20 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Cdk20Ratnucleoplasm located_inISOCDK20 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Cdk20Ratnucleus is_active_inIBAFB:FBgn0015618 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdk20Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Cdk20Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
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Molecular Function
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Object Symbol
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Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdk20RatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
Cdk20RatATP binding enablesIEAInterPro:IPR000719 and InterPro:IPR0174411600115GO_REF:0000002InterProGO_REF:0000002
Cdk20Ratcyclin-dependent protein serine/threonine kinase activity enablesIEAEC:2.7.11.221600115GO_REF:0000003UniProtGO_REF:0000003
Cdk20Ratkinase activity enablesIEAUniProtKB-KW:KW-04181600115GO_REF:0000043UniProtGO_REF:0000043
Cdk20Ratnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
Cdk20Ratprotein binding enablesISOCDK20 (Homo sapiens)1624291UniProtKB:P20794 more ...RGDPMID:21986944 and PMID:26871637
Cdk20Ratprotein binding enablesISOCdk20 (Mus musculus)1624291PR:Q3URV1 PMID:20159594RGDPMID:20159594
Cdk20Ratprotein kinase activity enablesIEAInterPro:IPR000719 and InterPro:IPR0082711600115GO_REF:0000002InterProGO_REF:0000002
Cdk20Ratprotein serine kinase activity enablesIEARHEA:179891600115GO_REF:0000116RHEAGO_REF:0000116
Cdk20Ratprotein serine/threonine kinase activity enablesIBACGD:CAL0000183529 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdk20Ratprotein serine/threonine kinase activity enablesIEAUniProtKB-KW:KW-07231600115GO_REF:0000043UniProtGO_REF:0000043
Cdk20Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Substance dependence low-density whole genome association study in two distinct American populations. Yu Y, etal., Hum Genet. 2008 Jun;123(5):495-506. doi: 10.1007/s00439-008-0501-0. Epub 2008 Apr 26.
PMID:12477932   PMID:15489334   PMID:18508765  



Cdk20
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr817706,863 - 717,828 (-)NCBIGRCr8
mRatBN7.217701,122 - 707,869 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl17701,124 - 707,826 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx17719,783 - 726,487 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0172,262,360 - 2,269,064 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.017717,194 - 723,898 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0171,935,900 - 1,942,867 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl171,936,163 - 1,942,865 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0171,924,304 - 1,931,008 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,221,255 - 6,227,959 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1176,221,336 - 6,227,959 (-)NCBI
Celera171,806,819 - 1,813,523 (+)NCBICelera
Cytogenetic Map17p14NCBI
CDK20
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38987,966,441 - 87,974,533 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl987,966,441 - 87,974,753 (-)EnsemblGRCh38hg38GRCh38
GRCh37990,581,356 - 90,589,448 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36989,771,176 - 89,779,487 (-)NCBINCBI36Build 36hg18NCBI36
Celera961,147,072 - 61,155,417 (-)NCBICelera
Cytogenetic Map9q22.1NCBI
HuRef960,404,214 - 60,412,553 (-)NCBIHuRef
CHM1_1990,729,461 - 90,737,804 (-)NCBICHM1_1
T2T-CHM13v2.09100,120,474 - 100,128,570 (-)NCBIT2T-CHM13v2.0
Cdk20
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391364,580,133 - 64,587,536 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1364,580,128 - 64,589,587 (+)EnsemblGRCm39 Ensembl
GRCm381364,432,319 - 64,439,722 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1364,432,314 - 64,441,773 (+)EnsemblGRCm38mm10GRCm38
MGSCv371364,533,861 - 64,541,029 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361364,447,324 - 64,454,492 (+)NCBIMGSCv36mm8
Celera1366,096,127 - 66,103,167 (+)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1333.26NCBI
CDK20
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21151,403,533 - 51,440,314 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1951,407,864 - 51,439,504 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0959,114,640 - 59,146,438 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1987,186,151 - 87,216,497 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl987,186,151 - 87,216,537 (+)Ensemblpanpan1.1panPan2
CDK20
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1197,623,126 - 97,662,668 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl197,622,998 - 97,662,662 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha198,085,092 - 98,124,432 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0198,234,542 - 98,273,720 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl198,234,315 - 98,319,825 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1197,861,596 - 97,900,723 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0197,579,491 - 97,618,492 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0198,340,675 - 98,379,772 (+)NCBIUU_Cfam_GSD_1.0
Cdk20
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049449,886,210 - 9,892,384 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936854812,575 - 817,202 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936854810,996 - 817,136 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK20
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11415,582 - 24,102 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214137,509 - 145,565 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDK20
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11298,522,596 - 98,530,734 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1298,522,333 - 98,530,817 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603886,845,817 - 86,854,163 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdk20
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248684,241,976 - 4,248,196 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248684,225,779 - 4,248,252 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Cdk20
31 total Variants

Predicted Target Of
Summary Value
Count of predictions:501
Count of miRNA genes:244
Interacting mature miRNAs:286
Transcripts:ENSRNOT00000024466
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122871563Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat

AW558027  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.217701,522 - 701,637 (-)MAPPERmRatBN7.2
Rnor_6.0171,942,352 - 1,942,466NCBIRnor6.0
Rnor_5.0171,930,493 - 1,930,607UniSTSRnor5.0
RGSC_v3.4176,221,656 - 6,221,770UniSTSRGSC3.4
Celera171,813,008 - 1,813,122UniSTS
Cytogenetic Map17p14UniSTS
RH133769  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.217701,335 - 701,519 (-)MAPPERmRatBN7.2
Rnor_6.0171,942,470 - 1,942,653NCBIRnor6.0
Rnor_5.0171,930,611 - 1,930,794UniSTSRnor5.0
RGSC_v3.4176,221,469 - 6,221,652UniSTSRGSC3.4
Celera171,813,126 - 1,813,309UniSTS
RH 3.4 Map1716.0UniSTS
Cytogenetic Map17p14UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000024466   ⟹   ENSRNOP00000024466
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl17701,124 - 707,826 (-)Ensembl
Rnor_6.0 Ensembl171,936,163 - 1,942,865 (+)Ensembl
RefSeq Acc Id: NM_001025752   ⟹   NP_001020923
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817706,863 - 713,567 (-)NCBI
mRatBN7.217701,122 - 707,826 (-)NCBI
Rnor_6.0171,936,163 - 1,942,867 (+)NCBI
Rnor_5.0171,924,304 - 1,931,008 (+)NCBI
RGSC_v3.4176,221,255 - 6,227,959 (-)RGD
Celera171,806,819 - 1,813,523 (+)RGD
Sequence:
RefSeq Acc Id: XR_005495307
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817708,823 - 717,828 (-)NCBI
mRatBN7.217703,057 - 707,869 (-)NCBI
Protein RefSeqs NP_001020923 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH98838 (Get FASTA)   NCBI Sequence Viewer  
  EDL84441 (Get FASTA)   NCBI Sequence Viewer  
  EDL84442 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000024466
  ENSRNOP00000024466.3
GenBank Protein Q4KM34 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001020923   ⟸   NM_001025752
- UniProtKB: Q4KM34 (UniProtKB/Swiss-Prot),   A6KQE7 (UniProtKB/TrEMBL),   A6KQE8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024466   ⟸   ENSRNOT00000024466
Protein kinase

Name Modeler Protein Id AA Range Protein Structure
AF-Q4KM34-F1-model_v2 AlphaFold Q4KM34 1-346 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13700265
Promoter ID:EPDNEW_R10789
Type:multiple initiation site
Name:Cdk20_1
Description:cyclin-dependent kinase 20
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0171,936,151 - 1,936,211EPDNEW


1 to 29 of 29 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-10547 BioCyc
Ensembl Genes ENSRNOG00000017991 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000024466 ENTREZGENE
  ENSRNOT00000024466.5 UniProtKB/Swiss-Prot
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7378980 IMAGE-MGC_LOAD
InterPro CDK UniProtKB/Swiss-Prot
  CDK20-like_STKc UniProtKB/Swiss-Prot
  Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot
KEGG Report rno:364666 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112893 IMAGE-MGC_LOAD
NCBI Gene 364666 ENTREZGENE
PANTHER CELL DIVISION PROTEIN KINASE UniProtKB/Swiss-Prot
  CYCLIN-DEPENDENT KINASE 20 UniProtKB/Swiss-Prot
Pfam Pkinase UniProtKB/Swiss-Prot
PhenoGen Cdk20 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000017991 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot
UniProt A6KQE7 ENTREZGENE, UniProtKB/TrEMBL
  A6KQE8 ENTREZGENE, UniProtKB/TrEMBL
  CDK20_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 29 of 29 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-29 Cdk20  cyclin-dependent kinase 20  Ccrk  cell cycle related kinase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ccrk  cell cycle related kinase  Ccrk_predicted  cell cycle related kinase (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ccrk_predicted  cell cycle related kinase (predicted)      Symbol and Name status set to approved 70820 APPROVED