B3gnt3 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3) - Rat Genome Database

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Advanced Search (OLGA)
Gene: B3gnt3 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3) Rattus norvegicus
Analyze
Symbol: B3gnt3
Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
RGD ID: 1305151
Description: Predicted to enable N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity. Predicted to be involved in poly-N-acetyllactosamine biosynthetic process and protein O-linked glycosylation. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in Golgi membrane. Orthologous to human B3GNT3 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3); PARTICIPATES IN lacto-series glycosphingolipid metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; bisphenol A; copper atom.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC290638; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,434,114 - 18,444,851 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1618,435,378 - 18,444,738 (-)EnsemblGRCr8
mRatBN7.21618,401,405 - 18,410,821 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,401,405 - 18,410,766 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1618,452,045 - 18,461,361 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,584,655 - 19,593,981 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,504,984 - 18,514,300 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,123,948 - 20,133,482 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,123,948 - 20,133,322 (-)Ensemblrn6Rnor6.0
Rnor_5.01619,984,402 - 19,994,118 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41618,892,320 - 18,901,908 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1618,604,001 - 18,613,336 (-)NCBICelera
RGSC_v3.11618,893,248 - 18,894,532 (-)NCBI
Cytogenetic Map16p14NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
Golgi membrane  (IBA,IEA)
membrane  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11042166  


Genomics

Comparative Map Data
B3gnt3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,434,114 - 18,444,851 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1618,435,378 - 18,444,738 (-)EnsemblGRCr8
mRatBN7.21618,401,405 - 18,410,821 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,401,405 - 18,410,766 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1618,452,045 - 18,461,361 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,584,655 - 19,593,981 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,504,984 - 18,514,300 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,123,948 - 20,133,482 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,123,948 - 20,133,322 (-)Ensemblrn6Rnor6.0
Rnor_5.01619,984,402 - 19,994,118 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41618,892,320 - 18,901,908 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1618,604,001 - 18,613,336 (-)NCBICelera
RGSC_v3.11618,893,248 - 18,894,532 (-)NCBI
Cytogenetic Map16p14NCBI
B3GNT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381917,794,791 - 17,813,576 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1917,794,697 - 17,814,175 (+)Ensemblhg38GRCh38
GRCh371917,905,947 - 17,924,385 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361917,766,919 - 17,785,385 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341917,766,948 - 17,784,890NCBI
Celera1917,807,662 - 17,826,113 (+)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1917,471,377 - 17,489,827 (+)NCBIHuRef
CHM1_11917,905,451 - 17,923,918 (+)NCBICHM1_1
T2T-CHM13v2.01917,928,853 - 17,947,690 (+)NCBIT2T-CHM13v2.0
B3gnt3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39872,144,017 - 72,155,270 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl872,143,400 - 72,154,433 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38871,691,373 - 71,702,626 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl871,690,756 - 71,701,789 (-)Ensemblmm10GRCm38
MGSCv37874,215,618 - 74,225,699 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36874,620,708 - 74,630,781 (-)NCBIMGSCv36mm8
Celera874,206,265 - 74,216,238 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.43NCBI
B3gnt3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555243,433,571 - 3,436,941 (-)Ensembl
ChiLan1.0NW_0049555243,432,797 - 3,436,941 (-)NCBIChiLan1.0ChiLan1.0
B3GNT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22022,669,117 - 22,680,080 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11921,675,947 - 21,686,889 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01917,277,686 - 17,295,646 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11918,252,347 - 18,270,388 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,252,347 - 18,270,161 (+)EnsemblpanPan2panpan1.1
B3GNT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12045,075,146 - 45,093,480 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2045,076,403 - 45,080,942 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2044,987,325 - 45,005,394 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02045,560,510 - 45,578,792 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2045,561,547 - 45,578,824 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,796,918 - 44,815,190 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02045,207,199 - 45,225,252 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02045,483,168 - 45,501,270 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
B3GNT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,934,958 - 59,952,859 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1259,934,948 - 59,952,861 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2259,504,383 - 59,522,285 (-)NCBISscrofa10.2Sscrofa10.2susScr3
B3GNT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,267,996 - 16,286,819 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl616,281,579 - 16,285,892 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660743,102,798 - 3,121,482 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
B3gnt3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,350,779 - 1,355,732 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249081,340,829 - 1,356,435 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
B3gnt3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11313,265,886 - 13,274,430 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in B3gnt3
75 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:111
Count of miRNA genes:82
Interacting mature miRNAs:97
Transcripts:ENSRNOT00000025363
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133425095Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16423421253708481Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161574800625801629Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16474422249744222Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16126734272Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126734272Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16435482249354822Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16423421249757901Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)161627818427244292Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338679049757901Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338679026128267Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126734272Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161773081872536785Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)161590580260905802Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16330168348301683Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
23 1 13 73 37 36 13 133 13 6 229 166 4 51 27 107 23 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000025363   ⟹   ENSRNOP00000025362
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1618,435,378 - 18,444,738 (-)Ensembl
mRatBN7.2 Ensembl1618,401,405 - 18,410,766 (-)Ensembl
Rnor_6.0 Ensembl1620,123,948 - 20,133,322 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000146152   ⟹   ENSRNOP00000107869
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1618,435,378 - 18,437,908 (-)Ensembl
RefSeq Acc Id: NM_001106068   ⟹   NP_001099538
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,435,378 - 18,444,738 (-)NCBI
mRatBN7.21618,401,405 - 18,410,766 (-)NCBI
Rnor_6.01620,123,948 - 20,133,322 (-)NCBI
Rnor_5.01619,984,402 - 19,994,118 (-)NCBI
RGSC_v3.41618,892,320 - 18,901,908 (-)RGD
Celera1618,604,001 - 18,613,336 (-)RGD
Sequence:
RefSeq Acc Id: XM_017600026   ⟹   XP_017455515
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,434,114 - 18,444,851 (-)NCBI
mRatBN7.21618,401,907 - 18,410,782 (-)NCBI
Rnor_6.01620,124,394 - 20,133,482 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039094301   ⟹   XP_038950229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,434,114 - 18,439,614 (-)NCBI
mRatBN7.21618,401,907 - 18,403,637 (-)NCBI
RefSeq Acc Id: NP_001099538   ⟸   NM_001106068
- Peptide Label: precursor
- UniProtKB: D3ZX31 (UniProtKB/TrEMBL),   A6K9X8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455515   ⟸   XM_017600026
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000025362   ⟸   ENSRNOT00000025363
RefSeq Acc Id: XP_038950229   ⟸   XM_039094301
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000107869   ⟸   ENSRNOT00000146152

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZX31-F1-model_v2 AlphaFold D3ZX31 1-378 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305151 AgrOrtholog
BioCyc Gene G2FUF-11827 BioCyc
BioCyc Pathway PWY-7837 [i antigen and I antigen biosynthesis] BioCyc
  PWY-7841 [neolacto-series glycosphingolipids biosynthesis] BioCyc
BioCyc Pathway Image PWY-7837 BioCyc
  PWY-7841 BioCyc
Ensembl Genes ENSRNOG00000018764 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025363 ENTREZGENE
  ENSRNOT00000025363.5 UniProtKB/TrEMBL
  ENSRNOT00000146152 ENTREZGENE
  ENSRNOT00000146152.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.550.50 UniProtKB/TrEMBL
InterPro Glyco_trans_31 UniProtKB/TrEMBL
KEGG Report rno:290638 UniProtKB/TrEMBL
NCBI Gene 290638 ENTREZGENE
PANTHER Glyco_trans_31 UniProtKB/TrEMBL
  N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 3 UniProtKB/TrEMBL
Pfam Galactosyl_T UniProtKB/TrEMBL
PhenoGen B3gnt3 PhenoGen
RatGTEx ENSRNOG00000018764 RatGTEx
UniProt A0ABK0LB36_RAT UniProtKB/TrEMBL
  A6K9X8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZX31 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 B3gnt3  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3   B3gnt3_predicted  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 B3gnt3_predicted  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED