Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tmx4 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | TMX4 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of TMX4 mRNA | CTD | PMID:22079256 | Tmx4 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Tmx4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TMX4 mRNA | CTD | PMID:36331819 | Tmx4 | Rat | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [APC protein affects the susceptibility to 1,2-Dimethylhydrazine] which results in decreased expression of TMX4 mRNA | CTD | PMID:27840820 | Tmx4 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Tmx4 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of TMX4 mRNA | CTD | PMID:22206623 | Tmx4 | Rat | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of TMX4 mRNA | CTD | PMID:32145629 | Tmx4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | TMX4 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TMX4 mRNA | CTD | PMID:21632981 | Tmx4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tmx4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TMX4 mRNA | CTD | PMID:21570461 | Tmx4 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Tmx4 (Mus musculus) | 6480464 | 2,2',4,4',5-brominated diphenyl ether affects the expression of TMX4 mRNA | CTD | PMID:38648751 | Tmx4 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of TMX4 mRNA | CTD | PMID:21346803 | Tmx4 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of TMX4 mRNA | CTD | PMID:24780913 | Tmx4 | Rat | 8-Br-cAMP | increases expression | ISO | TMX4 (Homo sapiens) | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TMX4 mRNA | CTD | PMID:20147733 | Tmx4 | Rat | aflatoxin B1 | decreases methylation | ISO | TMX4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TMX4 gene | CTD | PMID:27153756 | Tmx4 | Rat | all-trans-retinoic acid | increases expression | ISO | TMX4 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of TMX4 mRNA | CTD | PMID:23724009 | Tmx4 | Rat | all-trans-retinoic acid | decreases expression | ISO | TMX4 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of TMX4 mRNA | CTD | PMID:33167477 | Tmx4 | Rat | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of TMX4 mRNA | CTD | PMID:30779732 | Tmx4 | Rat | arsane | multiple interactions | ISO | TMX4 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of TMX4 more ... | CTD | PMID:39836092 | Tmx4 | Rat | arsenic atom | multiple interactions | ISO | TMX4 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of TMX4 more ... | CTD | PMID:39836092 | Tmx4 | Rat | arsenite(3-) | increases methylation | ISO | TMX4 (Homo sapiens) | 6480464 | arsenite results in increased methylation of TMX4 promoter | CTD | PMID:23974009 | Tmx4 | Rat | benzo[a]pyrene | increases expression | ISO | Tmx4 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TMX4 mRNA | CTD | PMID:22228805 | Tmx4 | Rat | benzo[a]pyrene | increases methylation | ISO | TMX4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TMX4 3' UTR | CTD | PMID:27901495 | Tmx4 | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | TMX4 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of TMX4 mRNA | CTD | PMID:26238291 | Tmx4 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Tmx4 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of TMX4 mRNA | CTD | PMID:33754040 | Tmx4 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TMX4 mRNA | CTD | PMID:25181051 | Tmx4 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TMX4 mRNA | CTD | PMID:30816183 | Tmx4 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of TMX4 gene | CTD | PMID:28505145 | Tmx4 | Rat | bisphenol F | increases expression | ISO | Tmx4 (Mus musculus) | 6480464 | bisphenol F results in increased expression of TMX4 mRNA | CTD | PMID:38685157 | Tmx4 | Rat | Brodifacoum | increases expression | EXP | | 6480464 | bromfenacoum results in increased expression of TMX4 protein | CTD | PMID:28903499 | Tmx4 | Rat | butanal | decreases expression | ISO | TMX4 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of TMX4 mRNA | CTD | PMID:26079696 | Tmx4 | Rat | cadmium atom | decreases expression | ISO | TMX4 (Homo sapiens) | 6480464 | Cadmium results in decreased expression of TMX4 mRNA | CTD | PMID:16439709 | Tmx4 | Rat | cadmium atom | multiple interactions | ISO | Tmx4 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TMX4 more ... | CTD | PMID:37236586 | Tmx4 | Rat | cadmium dichloride | increases expression | ISO | Tmx4 (Mus musculus) | 6480464 | Cadmium Chloride results in increased expression of TMX4 mRNA | CTD | PMID:20883709 | Tmx4 | Rat | cadmium dichloride | multiple interactions | ISO | Tmx4 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TMX4 more ... | CTD | PMID:37236586 | Tmx4 | Rat | cadmium dichloride | decreases expression | ISO | TMX4 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of TMX4 mRNA | CTD | PMID:38568856 | Tmx4 | Rat | carbon nanotube | increases expression | ISO | Tmx4 (Mus musculus) | 6480464 | Nanotubes, Carbon results in increased expression of TMX4 mRNA | CTD | PMID:25620056 | Tmx4 | Rat | choline | multiple interactions | ISO | Tmx4 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ... | CTD | PMID:20938992 | Tmx4 | Rat | chromium(6+) | affects expression | ISO | TMX4 (Homo sapiens) | 6480464 | chromium hexavalent ion affects the expression of TMX4 mRNA | CTD | PMID:30690063 | Tmx4 | Rat | cisplatin | increases expression | ISO | TMX4 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of TMX4 mRNA | CTD | PMID:27594783 | Tmx4 | Rat | cisplatin | increases expression | EXP | | 6480464 | Cisplatin results in increased expression of TMX4 mRNA | CTD | PMID:22023808 | Tmx4 | Rat | cisplatin | affects response to substance | ISO | TMX4 (Homo sapiens) | 6480464 | TMX4 protein affects the susceptibility to Cisplatin | CTD | PMID:16217747 | Tmx4 | Rat | cobalt dichloride | decreases expression | ISO | TMX4 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of TMX4 mRNA | CTD | PMID:19376846 | Tmx4 | Rat | coumestrol | multiple interactions | ISO | TMX4 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of TMX4 mRNA | CTD | PMID:19167446 | Tmx4 | Rat | Dibutyl phosphate | affects expression | ISO | TMX4 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of TMX4 mRNA | CTD | PMID:37042841 | Tmx4 | Rat | dimethyl sulfoxide | decreases expression | ISO | TMX4 (Homo sapiens) | 6480464 | Dimethyl Sulfoxide results in decreased expression of TMX4 mRNA | CTD | PMID:39709020 | Tmx4 | Rat | doxorubicin | decreases expression | ISO | TMX4 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TMX4 mRNA | CTD | PMID:29803840 | Tmx4 | Rat | ethanol | multiple interactions | ISO | Tmx4 (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of TMX4 mRNA | CTD | PMID:30319688 | Tmx4 | Rat | folic acid | multiple interactions | ISO | Tmx4 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ... | CTD | PMID:20938992 | Tmx4 | Rat | formaldehyde | decreases expression | ISO | TMX4 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of TMX4 mRNA | CTD | PMID:23649840 | Tmx4 | Rat | FR900359 | increases phosphorylation | ISO | TMX4 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of TMX4 protein | CTD | PMID:37730182 | Tmx4 | Rat | isoflavones | affects expression | ISO | TMX4 (Homo sapiens) | 6480464 | Isoflavones affects the expression of TMX4 mRNA | CTD | PMID:16365062 | Tmx4 | Rat | L-methionine | multiple interactions | ISO | Tmx4 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ... | CTD | PMID:20938992 | Tmx4 | Rat | lithium atom | increases expression | EXP | | 6480464 | Lithium results in increased expression of TMX4 protein | CTD | PMID:18296634 | Tmx4 | Rat | lithium hydride | increases expression | EXP | | 6480464 | Lithium results in increased expression of TMX4 protein | CTD | PMID:18296634 | Tmx4 | Rat | N-methyl-4-phenylpyridinium | increases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of TMX4 mRNA | CTD | PMID:28801915 | Tmx4 | Rat | nickel sulfate | decreases expression | ISO | TMX4 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of TMX4 mRNA | CTD | PMID:22714537 | Tmx4 | Rat | paracetamol | increases expression | ISO | TMX4 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of TMX4 mRNA | CTD | PMID:25704631 | Tmx4 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TMX4 mRNA | CTD | PMID:33387578 | Tmx4 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tmx4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TMX4 mRNA | CTD | PMID:36331819 | Tmx4 | Rat | potassium chromate | increases expression | ISO | TMX4 (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of TMX4 mRNA | CTD | PMID:22079256 | Tmx4 | Rat | potassium chromate | decreases expression | ISO | TMX4 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of TMX4 mRNA | CTD | PMID:22714537 | Tmx4 | Rat | potassium chromate | multiple interactions | ISO | TMX4 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of TMX4 mRNA | CTD | PMID:22079256 | Tmx4 | Rat | resveratrol | multiple interactions | ISO | TMX4 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of TMX4 mRNA | CTD | PMID:19167446 | Tmx4 | Rat | sodium arsenate | increases expression | ISO | Tmx4 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of TMX4 mRNA | CTD | PMID:39847705 | Tmx4 | Rat | sodium arsenite | decreases expression | ISO | TMX4 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of TMX4 mRNA | CTD | PMID:22714537|PMID:38568856 | Tmx4 | Rat | sodium arsenite | multiple interactions | ISO | TMX4 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of TMX4 more ... | CTD | PMID:39836092 | Tmx4 | Rat | sodium arsenite | increases expression | ISO | Tmx4 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of TMX4 mRNA | CTD | PMID:20883709 | Tmx4 | Rat | sodium fluoride | increases expression | ISO | Tmx4 (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of TMX4 protein | CTD | PMID:28918527 | Tmx4 | Rat | tert-butyl hydroperoxide | decreases expression | ISO | TMX4 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of TMX4 mRNA | CTD | PMID:15336504 | Tmx4 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of TMX4 mRNA | CTD | PMID:34492290 | Tmx4 | Rat | thiram | decreases expression | ISO | TMX4 (Homo sapiens) | 6480464 | Thiram results in decreased expression of TMX4 mRNA | CTD | PMID:38568856 | Tmx4 | Rat | titanium dioxide | decreases methylation | ISO | Tmx4 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of TMX4 promoter | CTD | PMID:35295148 | Tmx4 | Rat | titanium dioxide | increases methylation | ISO | Tmx4 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of TMX4 gene | CTD | PMID:35295148 | Tmx4 | Rat | triphenyl phosphate | affects expression | ISO | TMX4 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of TMX4 mRNA | CTD | PMID:37042841 | Tmx4 | Rat | trovafloxacin | increases expression | EXP | | 6480464 | trovafloxacin results in increased expression of TMX4 mRNA | CTD | PMID:24136188 | Tmx4 | Rat | urethane | increases expression | ISO | TMX4 (Homo sapiens) | 6480464 | Urethane results in increased expression of TMX4 mRNA | CTD | PMID:28818685 | Tmx4 | Rat | valproic acid | increases expression | ISO | TMX4 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TMX4 mRNA | CTD | PMID:23179753 | Tmx4 | Rat | valproic acid | affects expression | ISO | TMX4 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TMX4 mRNA | CTD | PMID:25979313 | Tmx4 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of TMX4 mRNA | CTD | PMID:23034163 | Tmx4 | Rat | vincristine | decreases expression | ISO | TMX4 (Homo sapiens) | 6480464 | Vincristine results in decreased expression of TMX4 mRNA | CTD | PMID:23649840 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















