Advanced Search (OLGA)

Gene: Prorp (protein only RNase P catalytic subunit) Rattus norvegicus

Analyze

Symbol:

Prorp

Name:

protein only RNase P catalytic subunit

RGD ID:

1305089

Description:

Predicted to enable ribonuclease P activity. Predicted to be involved in mitochondrial tRNA 5'-end processing and tRNA 5'-leader removal. Predicted to be located in mitochondrial nucleoid. Predicted to be part of mitochondrial ribonuclease P complex. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 54. Orthologous to human PRORP (protein only RNase P catalytic subunit); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; acrylamide; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC299050; mitochondrial ribonuclease P catalytic subunit; mitochondrial ribonuclease P protein 3; mitochondrial RNase P protein 3; Mrpp3; RGD1305089; similar to 1110008L16Rik protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PRORP (protein only RNase P catalytic subunit)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Prorp (protein only RNase P catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Prorp (protein only RNase P catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PRORP (protein only RNase P catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PRORP (protein only RNase P catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Prorp (protein only RNase P catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PRORP (protein only RNase P catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PRORP (protein only RNase P catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Prorp (protein only RNase P catalytic subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	PRORP (protein only RNase P catalytic subunit)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Prorp (protein only RNase P catalytic subunit)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:dkeyp-33b5.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	coa-6	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	mldr	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	prorp	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	78,404,821 - 78,497,562 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	78,405,980 - 78,497,761 (+)	Ensembl				GRCr8
mRatBN7.2	6	72,669,659 - 72,762,419 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	72,670,847 - 72,762,416 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	73,093,590 - 73,182,668 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	73,399,942 - 73,489,024 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	72,828,549 - 72,917,703 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	76,079,880 - 76,171,298 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	76,079,880 - 76,171,296 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	85,614,276 - 85,708,817 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	75,539,870 - 75,633,118 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	71,512,144 - 71,602,932 (+)	NCBI		Celera
RGSC_v3.1	6	75,543,495 - 75,636,184 (+)	NCBI
Cytogenetic Map	6	q23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

combined oxidative phosphorylation deficiency 54 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

17beta-estradiol (ISO)

2,2',5,5'-tetrachlorobiphenyl (EXP)

acrolein (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

auramine O (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP,ISO)

copper(II) sulfate (ISO)

corosolic acid (ISO)

cyclosporin A (ISO)

dicrotophos (ISO)

doxorubicin (ISO)

fenthion (ISO)

finasteride (EXP)

folic acid (ISO)

furan (EXP)

methapyrilene (ISO)

ochratoxin A (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

PCB138 (EXP)

potassium chromate (ISO)

quercetin (ISO)

rotenone (ISO)

sulindac (EXP)

thapsigargin (ISO)

thioacetamide (EXP)

topotecan (EXP)

tunicamycin (ISO)

urethane (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mitochondrial tRNA 5'-end processing (IBA,IEA,ISO,ISS)

tRNA 5'-leader removal (IBA)

tRNA processing (IEA)

Cellular Component

mitochondrial matrix (IEA,ISO)

mitochondrial nucleoid (IEA,ISO)

mitochondrial ribonuclease P complex (IBA,IEA,ISO,ISS)

mitochondrion (IEA,ISO)

Molecular Function

hydrolase activity (IEA)

metal ion binding (IEA)

nuclease activity (IEA)

ribonuclease P activity (IBA,IEA,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:18984158	PMID:24703694	PMID:25953853

Genomics

Comparative Map Data

Prorp
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	78,404,821 - 78,497,562 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	78,405,980 - 78,497,761 (+)	Ensembl				GRCr8
mRatBN7.2	6	72,669,659 - 72,762,419 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	72,670,847 - 72,762,416 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	73,093,590 - 73,182,668 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	73,399,942 - 73,489,024 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	72,828,549 - 72,917,703 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	76,079,880 - 76,171,298 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	76,079,880 - 76,171,296 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	85,614,276 - 85,708,817 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	75,539,870 - 75,633,118 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	71,512,144 - 71,602,932 (+)	NCBI		Celera
RGSC_v3.1	6	75,543,495 - 75,636,184 (+)	NCBI
Cytogenetic Map	6	q23	NCBI

PRORP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	35,121,839 - 35,277,622 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	35,121,842 - 35,277,622 (+)	Ensembl			hg38	GRCh38
GRCh37	14	35,591,045 - 35,746,828 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	34,661,527 - 34,813,022 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	14	15,455,607 - 15,607,100 (+)	NCBI		Celera
Cytogenetic Map	14	q13.2	NCBI
HuRef	14	15,704,222 - 15,857,638 (+)	NCBI		HuRef
CHM1_1	14	35,591,261 - 35,743,020 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	29,318,793 - 29,465,226 (+)	NCBI		T2T-CHM13v2.0

Prorp
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	55,349,422 - 55,429,276 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	55,346,362 - 55,429,318 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	12	55,302,637 - 55,382,492 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	55,299,577 - 55,382,533 (+)	Ensembl			mm10	GRCm38
MGSCv37	12	56,403,624 - 56,483,478 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	12	56,220,753 - 56,300,617 (+)	NCBI		MGSCv36	mm8
Celera	12	56,446,616 - 56,531,738 (+)	NCBI		Celera
Cytogenetic Map	12	C1	NCBI
cM Map	12	23.91	NCBI

Prorp
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	25,791,575 - 25,920,077 (-)	Ensembl
ChiLan1.0	NW_004955409	25,791,209 - 25,920,651 (-)	NCBI	ChiLan1.0	ChiLan1.0

PRORP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	36,432,152 - 36,590,190 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	35,648,655 - 35,808,108 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	15,871,707 - 16,027,634 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	34,056,234 - 34,209,657 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	34,056,620 - 34,209,657 (+)	Ensembl			panPan2	panpan1.1

PRORP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	13,885,734 - 14,007,224 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	13,681,902 - 13,803,857 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	13,991,929 - 14,113,298 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	13,992,144 - 14,113,292 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	13,693,596 - 13,814,946 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	13,758,157 - 13,879,746 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	14,047,450 - 14,169,639 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Prorp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	45,776,936 - 45,908,465 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936494	9,289,593 - 9,413,984 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936494	9,282,894 - 9,414,350 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PRORP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	64,620,517 - 64,762,428 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	64,620,514 - 64,763,272 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	69,530,089 - 69,535,675 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PRORP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	11,936,410 - 12,081,721 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	11,936,410 - 12,083,519 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666053	897,654 - 1,044,936 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Prorp
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	7	68,524,034 - 68,608,278 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Prorp
636 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	42
Count of miRNA genes:	41
Interacting mature miRNAs:	42
Transcripts:	ENSRNOT00000009304
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
9590290	Uminl2	Urine mineral level QTL 2	3.96	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	6	44510974	89510974	Rat
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	71278722	116278722	Rat
70176	Mcsm1	Mammary carcinoma susceptibility modifier QTL 1			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	64367996	109367996	Rat
2293088	Iddm28	Insulin dependent diabetes mellitus QTL 28	5.21		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	6	68767270	135411972	Rat
1558641	Cm47	Cardiac mass QTL 47	2.9	0.001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	6	63457441	94939581	Rat
4889933	Bss88	Bone structure and strength QTL 88	3.8		tibia size trait (VT:0100001)	tibia total bone volume (CMO:0001724)	6	53684921	98684921	Rat
737827	Hcar11	Hepatocarcinoma resistance QTL 11	4.4		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	6	46050607	116278722	Rat
724513	Uae14	Urinary albumin excretion QTL 14	6.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	46047353	91047353	Rat
634307	Bp141	Blood pressure QTL 141	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	40957564	85957564	Rat
1331743	Uae28	Urinary albumin excretion QTL 28	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	45153786	90153786	Rat
2293839	Kiddil2	Kidney dilation QTL 2	4.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	26618314	86868070	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	20859430	113082285	Rat
9590140	Scort4	Serum corticosterone level QTL 4	14.49	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	44510974	89510974	Rat
2301964	Bp323	Blood pressure QTL 323	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	86868070	Rat
9590306	Scort18	Serum corticosterone level QTL 18	2.88	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	44510974	89510974	Rat
2293841	Kiddil4	Kidney dilation QTL 4	4.4		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	26618314	86868070	Rat
4889848	Pur25	Proteinuria QTL 25	14	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	63037319	95934232	Rat
6893340	Cm77	Cardiac mass QTL 77	0.26	0.57	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	39028659	86867923	Rat
5684963	Bss99	Bone structure and strength QTL 99	3.1		tibia area (VT:1000281)	tibia area measurement (CMO:0001382)	6	53684921	98684921	Rat
1576302	Schws4	Schwannoma susceptibility QTL 4		0.0078	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	78204640	123204640	Rat
5684992	Bmd83	Bone mineral density QTL 82	4.8		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	6	53684921	98684921	Rat
1300075	Glom7	Glomerulus QTL 7	5.6	0.0000002	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	6	76937178	121937178	Rat
1300143	Rf14	Renal function QTL 14	2.92		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	40163183	85163183	Rat
6893332	Cm74	Cardiac mass QTL 74	0.4	0.64	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	63457441	94939581	Rat

Markers in Region

D6Got85

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	72,751,258 - 72,751,411 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	76,160,142 - 76,160,292	NCBI	Rnor6.0
Rnor_5.0	6	85,697,134 - 85,697,284	UniSTS	Rnor5.0
RGSC_v3.4	6	75,621,386 - 75,621,537	RGD	RGSC3.4
RGSC_v3.4	6	75,621,387 - 75,621,537	UniSTS	RGSC3.4
Celera	6	71,591,777 - 71,591,927	UniSTS
RGSC_v3.1	6	75,624,512 - 75,624,663	RGD
RH 2.0 Map	6	705.3	RGD
Cytogenetic Map	6	q23	UniSTS

RH137190

Rat Assembly	Chr	Position (strand)	Source
Celera	6	71,515,332 - 71,515,511	UniSTS
Celera	14	96,252,285 - 96,252,538	UniSTS
Cytogenetic Map	6	q23	UniSTS

RH139091

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	72,671,021 - 72,671,174 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	76,079,909 - 76,080,061	NCBI	Rnor6.0
Rnor_5.0	6	85,615,643 - 85,615,795	UniSTS	Rnor5.0
RGSC_v3.4	6	75,539,899 - 75,540,051	UniSTS	RGSC3.4
Celera	6	71,512,173 - 71,512,325	UniSTS
Cytogenetic Map	6	q23	UniSTS

AI407643

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	72,686,370 - 72,686,567 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	76,095,257 - 76,095,453	NCBI	Rnor6.0
Rnor_5.0	6	85,630,991 - 85,631,187	UniSTS	Rnor5.0
RGSC_v3.4	6	75,555,247 - 75,555,443	UniSTS	RGSC3.4
Celera	6	71,527,468 - 71,527,664	UniSTS
Cytogenetic Map	6	q23	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106730	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC115158	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC168878	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230894	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000009304 ⟹ ENSRNOP00000009306

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	78,405,980 - 78,497,560 (+)	Ensembl
mRatBN7.2 Ensembl	6	72,670,847 - 72,762,416 (+)	Ensembl
Rnor_6.0 Ensembl	6	76,079,880 - 76,171,296 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000100278 ⟹ ENSRNOP00000090601

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	78,406,456 - 78,497,560 (+)	Ensembl
mRatBN7.2 Ensembl	6	72,671,506 - 72,762,416 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115283 ⟹ ENSRNOP00000084560

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	78,405,980 - 78,497,761 (+)	Ensembl
mRatBN7.2 Ensembl	6	72,670,847 - 72,760,162 (+)	Ensembl

RefSeq Acc Id:

NM_001106730 ⟹ NP_001100200

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	78,406,142 - 78,497,562 (+)	NCBI
mRatBN7.2	6	72,670,993 - 72,762,417 (+)	NCBI
Rnor_6.0	6	76,079,880 - 76,171,298 (+)	NCBI
Rnor_5.0	6	85,614,276 - 85,708,817 (+)	NCBI
RGSC_v3.4	6	75,539,870 - 75,633,118 (+)	RGD
Celera	6	71,512,144 - 71,602,932 (+)	RGD

Sequence:

show sequence

ATTCCCACCCCCTTCTCTGAAGAGTTTTGCGTCCTGGAGAGAGTTGTGAAAAGCAAGGAACCCT
AGACTGGCTTTTCTTGCTGCTGCTGGAACTACGGTTGGTGGTTCCTGACTGATTTTATTTATTT
TCGTGTTCTCGCTCCCGTGATATCCCGCCCCTCTTCAGGACCGTAGTAATCCGCAGGAGTTAAA
CTGGGAGGTCCATGTGCTTTTTCTTCAGATTCGAAAATTGGAAGGTAACAGGCACCTCAGGATT
TCCGTTCCGTCTTCTGGTTTAGGGATTGCTACTAGTGTTGGATGTCCTTGGATTGTTATTTAAT
GAATAGAACTCTTGTGCTTTCCTTCACATTAAATCGCTCCAAACATATAATCTTGGCTTGTTTA
TAAGGGAGAAACAAAAAAAAAAAAAAAATTCAAGAACTGGGCTTCCACTGTCTTCAGCCCTCAA
TACCTTAATTTTACATAGTGGAGTGAAGCTGTTTTTAGAAGTTGTCTCATTCAACTCACAGCAG
AATGACTTTCTATTTGTCTGGTTTTCGGAGCTTTCTGAAACTTTGGAAGAGCAACCCTTATTTT
GAACTAGGCCCTGCGACCTCTTCTGCCTCTTTCTTTCTCGGGGTTCACTGTGTCATCGGGAACC
AACAGAGATGGTTTTCTGTTAAACCTACCACCCCTCCAAATAGCAAAATACTCAATCTACTGGT
TACTAAAGCTAGAACACTCAAGAAAGGAAATGACAGCAATAAACAAGCTTCTTCTGGTCCTCAT
TATTTTGCTGCTGGAGAGGCTAAGAAGAGGTCCCACCTAAGTGGTAACCCTCAGAATCAAGGTC
ACACCTTGCCTGTGAAAAGCACTGTCCAACTCCCAACTAAACCTTTGAATTCCGAAGAGTGGGA
TAAACTTAAAGAAGATTTCAAAGGAAAGGCCAGTTTCGAAGACTTCGTCATTTCACAGATGACA
CGCAGCTGCAGTTCAGTCGATGTGGCCAAGTCTCTCCTGGCTTGGGTAGCAGCAAAGAACAATG
GTATCGTGGGGTATAATTTACTCGTCAAGTATTTATATCTCTGTGTCTTTCATAAGCAGACGTC
AGAAGTTATCGATGTCTACGAAATAATGAAAGCCAAGTACAAGAGTTTAGAATCTGGGGGTTAC
ACCCTTCTCATCCGGGGATTAATCCACTCAGACAGATGGAGAGAGGCCTTGTTGCTGTTAGAAG
ATATTAAAAAAGTCATGGTCCCTTCCAAAAAGAACTATGGTGACTGTATACAAGGAGCCCTCCT
TCATCAAGATGTGAACGTGGCTTGGAGTTTGTATCAGGAGTTGGTAGGTCATAATCTCATCCCT
CTGTTGGAAACTTTAAAAGCCTTCTTTGATCATGGCAAAGACATGAATGATGATCAGTATTCAA
ACCAACTCCTGGACATTCTTTTGTATCTAAGGAATAATCAGCTGTATCCTGGAGAGTCATTTGC
ACACAGTATAAAGACGTGGTTTGAAAGCATTCCTGGAAGACAATGGAAAGGACAGTTCACCACA
ATTCAGAAAAGTGGCCAGTGTTCAAGCTGTGGCAGAGCCATAGAGTCTATCCATCTGAGTCCAG
AAGAGTATGAATTTCTCAAGGAAACAATCATGAGAGATGTGATTGATGGTGGCGACCAGTACAA
GAAGACGACACCTCAGGAACTGAAGAGATTTGAGCGCTTTGTGAAGTCCTGTCCTCCTTTTGAT
ATTGTTATTGATGGCCTCAATGTTGCAAAAATGTTTCCTAAGGGTCGTGAATCTCAAAATCTCC
TGGGTATAGTTTCTCAACTGGCCCAGCAGAATCTACAGCTGCTGGTCCTGGGCCGGAAGCACAT
GCTGAGGCCCAGTTCCCAGTGGAGAAAGGACGAGATGGAGCAGGTGCGGAAGCAAGCCCACTGT
TTTTTTGCTGATAACATCTCGGAGGACGATCCTTTCCTTCTGTATGCCACACTGAACTCAGGCA
GTCACTGCAAGTTTATCACCAAAGACCTGTTGCGGGACCACAAGGCCTGCCTGCCTGATGCCCG
GGCTCAGCGCCTGTTCTTTAAGTGGCAGCAGGGCCATCAGCTGGCAATCACGAAAGGGTTTCTG
AAATCAAAACTAACCTTCCAGCATATTCTCAGCTATGACACTGTGGTGCAGACGACTGGAGACA
CCTGGCACATTCCTTATGATGAAGACCTGGTGCCGAGATCCTCCTGTGAAGTGCCCACCAAATG
GCTGTGCCTCCAGAGAAAGACCCCTGCCCCCTGCTGAGTCGTACTGGCCTGGCTTCCTGGCATG
ACCTGTGTTCTGGAAATAAAAGGATTTTAGTAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039111975 ⟹ XP_038967903

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	78,404,821 - 78,497,562 (+)	NCBI
mRatBN7.2	6	72,669,659 - 72,762,419 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100200	(Get FASTA)	NCBI Sequence Viewer
	XP_038967903	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI68878	(Get FASTA)	NCBI Sequence Viewer
	B5DF07	(Get FASTA)	NCBI Sequence Viewer
	EDM03424	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000009306
	ENSRNOP00000009306.4

RefSeq Acc Id:	NP_001100200 ⟸ NM_001106730
- Peptide Label:	precursor
- UniProtKB:	B5DF07 (UniProtKB/Swiss-Prot), A0A8I6AEM3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTFYLSGFRSFLKLWKSNPYFELGPATSSASFFLGVHCVIGNQQRWFSVKPTTPPNSKILNLLV TKARTLKKGNDSNKQASSGPHYFAAGEAKKRSHLSGNPQNQGHTLPVKSTVQLPTKPLNSEEWD KLKEDFKGKASFEDFVISQMTRSCSSVDVAKSLLAWVAAKNNGIVGYNLLVKYLYLCVFHKQTS EVIDVYEIMKAKYKSLESGGYTLLIRGLIHSDRWREALLLLEDIKKVMVPSKKNYGDCIQGALL HQDVNVAWSLYQELVGHNLIPLLETLKAFFDHGKDMNDDQYSNQLLDILLYLRNNQLYPGESFA HSIKTWFESIPGRQWKGQFTTIQKSGQCSSCGRAIESIHLSPEEYEFLKETIMRDVIDGGDQYK KTTPQELKRFERFVKSCPPFDIVIDGLNVAKMFPKGRESQNLLGIVSQLAQQNLQLLVLGRKHM LRPSSQWRKDEMEQVRKQAHCFFADNISEDDPFLLYATLNSGSHCKFITKDLLRDHKACLPDAR AQRLFFKWQQGHQLAITKGFLKSKLTFQHILSYDTVVQTTGDTWHIPYDEDLVPRSSCEVPTKW LCLQRKTPAPC hide sequence

Ensembl Acc Id:

ENSRNOP00000009306 ⟸ ENSRNOT00000009304

RefSeq Acc Id:	XP_038967903 ⟸ XM_039111975
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000090601 ⟸ ENSRNOT00000100278

Ensembl Acc Id:

ENSRNOP00000084560 ⟸ ENSRNOT00000115283

Protein Domains

PRORP

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B5DF07-F1-model_v2	AlphaFold	B5DF07	1-587	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305089	AgrOrtholog
BioCyc Gene	G2FUF-37489	BioCyc
Ensembl Genes	ENSRNOG00000007043	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000009304	ENTREZGENE
	ENSRNOT00000009304.5	UniProtKB/Swiss-Prot
Gene3D-CATH	1.25.40.10	UniProtKB/Swiss-Prot
	3.40.50.11980	UniProtKB/Swiss-Prot
InterPro	MRPP3	UniProtKB/Swiss-Prot
	PRORP_C	UniProtKB/Swiss-Prot
	TPR-like_helical_dom_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:299050	UniProtKB/Swiss-Prot
NCBI Gene	299050	ENTREZGENE
PANTHER	PTHR13547:SF1	UniProtKB/Swiss-Prot
	UNCHARACTERIZED	UniProtKB/Swiss-Prot
Pfam	PRORP	UniProtKB/Swiss-Prot
PhenoGen	Prorp	PhenoGen
RatGTEx	ENSRNOG00000007043	RatGTEx
UniProt	A0A8I6A1L4_RAT	UniProtKB/TrEMBL
	A0A8I6AEM3	ENTREZGENE, UniProtKB/TrEMBL
	B5DF07	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-08-09	Prorp	protein only RNase P catalytic subunit	RGD1305089	similar to 1110008L16Rik protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1305089	similar to 1110008L16Rik protein	RGD1305089_predicted	similar to 1110008L16Rik protein (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-20	RGD1305089_predicted	similar to 1110008L16Rik protein (predicted)	LOC299050_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC299050_predicted	similar to 1110008L16Rik protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - OMIM