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Gene: Purg (purine-rich element binding protein G) Rattus norvegicus

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Symbol:

Purg

Name:

purine-rich element binding protein G

RGD ID:

1305088

Description:

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and purine-rich negative regulatory element binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus and synapse. Orthologous to human PURG (purine rich element binding protein G); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC361162; purine-rich element-binding protein gamma

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PURG (purine rich element binding protein G)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Purg (purine-rich element binding protein G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Purg (purine rich element binding protein G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PURG (purine rich element binding protein G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PURG (purine rich element binding protein G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Purg (purine rich element binding protein G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PURG (purine rich element binding protein G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PURG (purine rich element binding protein G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Purg (purine rich element binding protein G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Purg (purine rich element binding protein G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ADRA2C (adrenoceptor alpha 2C)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	PURG (purine rich element binding protein G)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Purg (purine-rich element binding protein G)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Purg (purine-rich element binding protein G)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	purg (purine-rich element binding protein G)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	plp-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	plp-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Pur-alpha	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Pur-alpha	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	plp-2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	purg	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	purg	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	65,435,371 - 65,466,437 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	65,412,238 - 65,466,185 (-)	Ensembl				GRCr8
mRatBN7.2	16	58,732,327 - 58,763,356 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	58,720,335 - 58,763,359 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	64,099,302 - 64,100,856 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	67,512,980 - 67,514,534 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	62,733,546 - 62,735,100 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	62,427,933 - 62,483,295 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	62,481,685 - 62,483,137 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	62,094,495 - 62,148,088 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	62,505,099 - 62,535,638 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	56,794,895 - 56,796,104 (-)	NCBI		Celera
RGSC_v3.1	16	62,533,810 - 62,535,016 (-)	NCBI
Cytogenetic Map	16	q12.3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

C60 fullerene (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

choline (ISO)

diarsenic trioxide (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

entinostat (ISO)

fenvalerate (EXP)

folic acid (ISO)

L-methionine (ISO)

lithium chloride (ISO)

methimazole (EXP)

panobinostat (ISO)

paracetamol (EXP)

PCB138 (EXP)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

tebuconazole (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

valproic acid (EXP,ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

regulation of transcription by RNA polymerase II (IBA)

Cellular Component

nucleus (IBA)

synapse (IEA,ISO)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

purine-rich negative regulatory element binding (IBA,IEA)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IBA,IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:22681889

Genomics

Comparative Map Data

Purg
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	65,435,371 - 65,466,437 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	65,412,238 - 65,466,185 (-)	Ensembl				GRCr8
mRatBN7.2	16	58,732,327 - 58,763,356 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	58,720,335 - 58,763,359 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	64,099,302 - 64,100,856 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	67,512,980 - 67,514,534 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	62,733,546 - 62,735,100 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	62,427,933 - 62,483,295 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	62,481,685 - 62,483,137 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	62,094,495 - 62,148,088 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	62,505,099 - 62,535,638 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	56,794,895 - 56,796,104 (-)	NCBI		Celera
RGSC_v3.1	16	62,533,810 - 62,535,016 (-)	NCBI
Cytogenetic Map	16	q12.3	NCBI

PURG
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	30,995,802 - 31,033,356 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	30,995,802 - 31,033,715 (-)	Ensembl			hg38	GRCh38
GRCh37	8	30,853,318 - 30,890,872 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	30,972,863 - 31,010,773 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	8	31,007,899 - 31,009,859	NCBI
Celera	8	29,813,365 - 29,851,272 (-)	NCBI		Celera
Cytogenetic Map	8	p12	NCBI
HuRef	8	29,398,483 - 29,445,354 (-)	NCBI		HuRef
CHM1_1	8	31,054,490 - 31,092,675 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	31,276,938 - 31,314,481 (-)	NCBI		T2T-CHM13v2.0

Purg
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	33,875,650 - 33,907,500 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	33,876,353 - 33,907,495 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	33,385,619 - 33,417,472 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	33,386,325 - 33,417,467 (+)	Ensembl			mm10	GRCm38
MGSCv37	8	34,496,797 - 34,527,941 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	34,852,260 - 34,853,323 (+)	NCBI		MGSCv36	mm8
Celera	8	36,023,906 - 36,054,729 (+)	NCBI		Celera
Cytogenetic Map	8	A3	NCBI
cM Map	8	20.3	NCBI

Purg
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955463	7,460,533 - 7,494,354 (-)	Ensembl
ChiLan1.0	NW_004955463	7,460,533 - 7,495,106 (-)	NCBI	ChiLan1.0	ChiLan1.0

PURG
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	49,574,695 - 49,612,548 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	25,290,905 - 25,328,770 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	30,315,336 - 30,353,180 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	27,503,358 - 27,540,290 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	27,503,358 - 27,540,290 (-)	Ensembl			panPan2	panpan1.1

PURG
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	33,304,992 - 33,342,135 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	33,305,477 - 33,341,371 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	33,764,036 - 33,802,567 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	35,330,767 - 35,369,349 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	35,330,761 - 35,368,628 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	33,429,325 - 33,467,917 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	34,004,056 - 34,042,644 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	34,122,484 - 34,161,050 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Purg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	56,501,910 - 56,539,510 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936792	824,276 - 861,882 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936792	824,162 - 861,943 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PURG
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	54,094,639 - 54,100,680 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	54,095,021 - 54,133,904 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	61,464,773 - 61,503,813 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PURG
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	29,109,478 - 29,149,443 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	29,109,552 - 29,149,066 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666052	12,942,671 - 12,983,362 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Purg
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624780	13,052,024 - 13,085,529 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624780	13,051,994 - 13,085,431 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Purg
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	13	53,563,095 - 53,592,721 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Purg
184 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	22
Count of miRNA genes:	22
Interacting mature miRNAs:	22
Transcripts:	ENSRNOT00000020683
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2300163	Bmd64	Bone mineral density QTL 64	5.3	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	16	44455123	89455123	Rat
70215	Niddm29	Non-insulin dependent diabetes mellitus QTL 29	3.54		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	16	36928782	81928782	Rat
1578768	Stresp22	Stress response QTL 22	2.8		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	16	41992064	86992064	Rat
737826	Alc11	Alcohol consumption QTL 11	3.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4234212	66955197	Rat
2302057	Pia29	Pristane induced arthritis QTL 29	3.6	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	16	28468701	73468701	Rat
7205510	Activ5	Activity QTL 5	3.78	0.00028	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	49099196	91442908	Rat
631525	Pia14	Pristane induced arthritis QTL 14	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	16	62414464	75736480	Rat
1357403	Slep4	Serum leptin concentration QTL 4	3.91		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	32361043	77361043	Rat
7411648	Foco22	Food consumption QTL 22	15	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	59428714	91442908	Rat
8694453	Bw172	Body weight QTL 172	8.33	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	16	31058039	76058039	Rat
1298529	Arunc1	Aerobic running capacity QTL 1	4		exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	16	34398294	79398294	Rat
2312663	Slep9	Serum leptin concentration QTL 9		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	839086	66195506	Rat
2312660	Bw95	Body weight QTL 95		0.05	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	16	839086	66195506	Rat
6903294	Stl30	Serum triglyceride level QTL 30	2.6	0.0013	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	16	31885271	76885271	Rat
2293690	Bss45	Bone structure and strength QTL 45	5.13	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	16	44455123	89455123	Rat
8694364	Abfw7	Abdominal fat weight QTL 7	12.22	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	16	59428714	91442908	Rat
2312666	Insul16	Insulin level QTL 16		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	16	839086	66195506	Rat
8694429	Bw164	Body weight QTL 164	5	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	16	59428714	91442908	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17730818	72536785	Rat
2312669	Stl23	Serum triglyceride level QTL 23		0.01	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	16	839086	66195506	Rat

Markers in Region

D16Rat63

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	16	65,458,749 - 65,458,947 (+)	Marker Load Pipeline
mRatBN7.2	16	58,755,705 - 58,755,903 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	62,475,969 - 62,476,166	NCBI	Rnor6.0
Rnor_5.0	16	62,140,781 - 62,140,978	UniSTS	Rnor5.0
RGSC_v3.4	16	62,527,963 - 62,528,160	UniSTS	RGSC3.4
RGSC_v3.4	16	62,527,962 - 62,528,160	RGD	RGSC3.4
Celera	16	56,789,123 - 56,789,320	UniSTS
RGSC_v3.1	16	62,528,038 - 62,528,235	RGD
RH 3.4 Map	16	563.61	UniSTS
RH 3.4 Map	16	563.61	RGD
SHRSP x BN Map	16	22.73	RGD
SHRSP x BN Map	16	22.73	UniSTS
Cytogenetic Map	16	q12.3	UniSTS

D16Nkg85

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	58,739,750 - 58,739,923 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	62,460,014 - 62,460,186	NCBI	Rnor6.0
Rnor_5.0	16	62,124,826 - 62,124,998	UniSTS	Rnor5.0
RGSC_v3.4	16	62,512,008 - 62,512,180	UniSTS	RGSC3.4
Celera	16	56,773,168 - 56,773,340	UniSTS
Cytogenetic Map	16	q12.3	UniSTS

RH139188

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	58,738,220 - 58,738,424 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	62,458,484 - 62,458,687	NCBI	Rnor6.0
Rnor_5.0	16	62,123,296 - 62,123,499	UniSTS	Rnor5.0
RGSC_v3.4	16	62,510,478 - 62,510,681	UniSTS	RGSC3.4
Celera	16	56,771,638 - 56,771,841	UniSTS
RH 3.4 Map	16	563.8	UniSTS
Cytogenetic Map	16	q12.3	UniSTS

UniSTS:235866

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	58,732,438 - 58,732,768 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	62,452,702 - 62,453,031	NCBI	Rnor6.0
Rnor_5.0	16	62,117,514 - 62,117,843	UniSTS	Rnor5.0
RGSC_v3.4	16	62,504,696 - 62,505,025	UniSTS	RGSC3.4
Celera	16	56,765,856 - 56,766,185	UniSTS
Cytogenetic Map	16	q12.3	UniSTS

UniSTS:488917

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	58,761,620 - 58,762,687 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	62,481,884 - 62,482,950	NCBI	Rnor6.0
Rnor_5.0	16	62,146,696 - 62,147,762	UniSTS	Rnor5.0
RGSC_v3.4	16	62,533,879 - 62,534,945	UniSTS	RGSC3.4
Celera	16	56,795,038 - 56,796,104	UniSTS
Cytogenetic Map	16	q12.3	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	167	91	90	59	86	59	6	355	186	11	147	86	92	31	20	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191554	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006253233	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006253234	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006253235	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600183	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600184	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000020683 ⟹ ENSRNOP00000020683

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	65,412,238 - 65,466,185 (-)	Ensembl
mRatBN7.2 Ensembl	16	58,720,335 - 58,763,359 (-)	Ensembl
Rnor_6.0 Ensembl	16	62,481,685 - 62,483,137 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000134931 ⟹ ENSRNOP00000109748

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	65,435,304 - 65,466,185 (-)	Ensembl

RefSeq Acc Id:

NM_001191554 ⟹ NP_001178483

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	65,464,522 - 65,466,076 (-)	NCBI
mRatBN7.2	16	58,761,478 - 58,763,032 (-)	NCBI
Rnor_6.0	16	62,481,741 - 62,482,950 (-)	NCBI
Rnor_5.0	16	62,094,495 - 62,148,088 (-)	NCBI
Celera	16	56,794,895 - 56,796,104 (-)	NCBI

Sequence:

show sequence

AACGCAGGTGCGGCTGAAGATGGAAAGAGCCAGGAGAAGGGGAGGCGGCGGCGGCGGCGGCGGC
GGCCGTGGCCGCGGAGCCAAGAATGTAGGGGGCTCTGGCCTAAGCAAGAGTAGACTCTATCCCC
AGGCCCAGCATTCTCACTACCCCCACTACTCCGCGTCAGCCACCCCTAATCAGTCCGGGGGCGC
ATCCGAAATCCAGGAGCTGGCCTCCAAACGAGTGGACATCCAGAAAAAGAGGTTTTACCTAGAC
GTGAAGCAAAGCTCCCGGGGCCGCTTCCTAAAGATAGCCGAAGTCTGGATAGGGAGAGGCCGGC
AGGACAATATCAGAAAGAGTAAACTGACCCTCTCCCTGTCCGTAGCAGCAGAGCTGAAGGACTG
TCTAGGCGACTTCATCGAGCACTATGCCCACCTGGGCCTGAAAGGCCACAGGCAAGAGCATGGC
CAGAGCAAAGAGCAAGTCTCCAGGAGGCGGCAGAAGCACTCTGCACCCTCCCCACCGGTGTCAG
TGGGGTCAGAAGAGCATCCTCACAGTGTCCTCAAAACGGACTATATAGAGAGGGACAATAGGAA
ATACTACCTGGACCTAAAAGAGAATCAACGAGGTCGCTTCCTAAGGATTAGACAAACCATGATG
CGGGGCACTGGCATGATAGGTTATTTTGGCCACAGTTTGGGCCAGGAACAGACTATTGTCCTCC
CAGCGCAAGGTATGATTGAATTTCGGGATGCCTTGGTTCAGCTGATTGAAGACTATGGCGAAGG
AGACATAGAAGAACGAAGGGGTGGAGACGACGACCCACTTGAACTCCCAGAGGGGACCTCTTTC
AGAGTGGACAATAAAAGGTTCTACTTTGATGTGGGCTCTAATAAATATGGAATTTTCCTGAAGG
TAAGTGAGGTGAGGCCACCTTACCGTAATACTATTACTGTTCCATTCAAAGCTTGGACAAGGTT
TGGGGAGAATTTTATCAAGTATGAAGAAGAAATGAGGAAAATTTGCAACAGCCATAAAGAAAAG
AGAATGGATGGCCGGCGGGCCAGTGGTGAAGAACAAGGATGCCTGGACTAGCGTGAAATTGAAC
TCCAGCAGGCAAAATTTAGAAATCAGTTAATTGGCTAAAAGTACTGATCCGTAACCATGACCAT
TTGAAGAAGTTTCTCCTCTTTTGGGCCCTTTGTTATTAGTGATACCTCTAAGAGTTTATGCGTA
AA

hide sequence

RefSeq Acc Id:

XM_006253235 ⟹ XP_006253297

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	65,435,371 - 65,466,437 (-)	NCBI
mRatBN7.2	16	58,732,327 - 58,763,356 (-)	NCBI
Rnor_6.0	16	62,452,590 - 62,483,295 (-)	NCBI
Rnor_5.0	16	62,094,495 - 62,148,088 (-)	NCBI

Sequence:

show sequence

GGGCGGCGGCTGCGGCGGAGGGGCCGAGAGCTGGCGGCGGCGGCGGTGGTCGTGAAGGGCATCG
GTGGCGGTGACGGAGATGATCTGAAGATGGAAAGAGCCAGGAGAAGGGGAGGCGGCGGCGGCGG
CGGCGGCGGCCGTGGCCGCGGAGCCAAGAATGTAGGGGGCTCTGGCCTAAGCAAGAGTAGACTC
TATCCCCAGGCCCAGCATTCTCACTACCCCCACTACTCCGCGTCAGCCACCCCTAATCAGTCCG
GGGGCGCATCCGAAATCCAGGAGCTGGCCTCCAAACGAGTGGACATCCAGAAAAAGAGGTTTTA
CCTAGACGTGAAGCAAAGCTCCCGGGGCCGCTTCCTAAAGATAGCCGAAGTCTGGATAGGGAGA
GGCCGGCAGGACAATATCAGAAAGAGTAAACTGACCCTCTCCCTGTCCGTAGCAGCAGAGCTGA
AGGACTGTCTAGGCGACTTCATCGAGCACTATGCCCACCTGGGCCTGAAAGGCCACAGGCAAGA
GCATGGCCAGAGCAAAGAGCAAGTCTCCAGGAGGCGGCAGAAGCACTCTGCACCCTCCCCACCG
GTGTCAGTGGGGTCAGAAGAGCATCCTCACAGTGTCCTCAAAACGGACTATATAGAGAGGGACA
ATAGGAAATACTACCTGGACCTAAAAGAGAATCAACGAGGTCGCTTCCTAAGGATTAGACAAAC
CATGATGCGGGGCACTGGCATGATAGGTTATTTTGGCCACAGTTTGGGCCAGGAACAGACTATT
GTCCTCCCAGCGCAAGGTATGATTGAATTTCGGGATGCCTTGGTTCAGCTGATTGAAGACTATG
GCGAAGGAGACATAGAAGAACGAAGGGGTGGAGACGACGACCCACTTGAACTCCCAGAGGGGAC
CTCTTTCAGAGTGGACAATAAAAGGTTCTACTTTGATGTGGGCTCTAATAAATATGGAATTTTC
CTGAAGCTCACAAATTTCCCTAAATCCAGAGAGAATCTCAACCTTTTTCACTGTTGTCAGACCA
AGCGTAAGGAGCAGCCCCATGACACTACAAACACAGTTGAGGAATAAGGACTAACCCCTTACGT
TACTCTCCAGAATAAAGGCGTTCGGTGAAAGAAATGAGCTGAAGTACATCGTGAACGCAAGGCT
TCTGTGCTTGGCGTTCCTGCATGGAAGGGAAAACAGGTATGGACGCCATTGGCATCAGTTCCCA
CTGACCTTATGGGAAAGCCCTCCACCACACTGGAGGACTGTTGGACTCAGTCTGGTTTGCCAGG
GAGCGGGCGGGGGCTGCTTCTTTAACTCTTTAAGCCTTTCATTTTCCAAATAGCTATTTGCCAG
CATTGAGGGAGAAGACATGGAGGCTTGAAAATACTTTCTTAAGAGATCATGTAACTGTCTAACT
CTGGATTTAAATTTTGAGGAGGGAGGATCACTTCAATCCGCTGCCTCGTATAAAGAGACATTTT
TTTAAATCTGTAACTGCTTTAGTGTTAACAGGGTACAAGGTGGTTTTGTCCTGTATTGTATTTC
AAAGGTTCTCATCGGTTGTGACTGTATTGTACTGTATGAAAAGAAGTCAGAACTTGCCTTGTAT
CGTTTATAATGGACCATAACTCATATGAATTCAGTTTTCATGTTCCAAATTTTTCAGTGATGCA
TGTTCACAGTTAGGTCCTAAAATCCTGTGGTGCTAATTCCTCCATAATCCAATGGTGCTTTTTG
TGGATGCTAACTGCACACATGCTGAACAAAGCTTGAAATTCAAAAGTTCCCTCCTTCCTCTGTT
TATATGAAGTAAAATAAAATAACTTGAATTTGTCTCAAAGTATCACTGACAATCTAATAAACTG
GTTTATATGTGTCATTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001178483	(Get FASTA)	NCBI Sequence Viewer
	XP_006253297	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM09137	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000020683.5
	ENSRNOP00000109748
	ENSRNOP00000109748.1

RefSeq Acc Id:

NP_001178483 ⟸ NM_001191554

- UniProtKB:

A6IVT5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MERARRRGGGGGGGGGRGRGAKNVGGSGLSKSRLYPQAQHSHYPHYSASATPNQSGGASEIQEL
ASKRVDIQKKRFYLDVKQSSRGRFLKIAEVWIGRGRQDNIRKSKLTLSLSVAAELKDCLGDFIE
HYAHLGLKGHRQEHGQSKEQVSRRRQKHSAPSPPVSVGSEEHPHSVLKTDYIERDNRKYYLDLK
ENQRGRFLRIRQTMMRGTGMIGYFGHSLGQEQTIVLPAQGMIEFRDALVQLIEDYGEGDIEERR
GGDDDPLELPEGTSFRVDNKRFYFDVGSNKYGIFLKVSEVRPPYRNTITVPFKAWTRFGENFIK
YEEEMRKICNSHKEKRMDGRRASGEEQGCLD

hide sequence

RefSeq Acc Id:	XP_006253297 ⟸ XM_006253235
- Peptide Label:	isoform X1
- UniProtKB:	D3ZYS1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MERARRRGGGGGGGGGRGRGAKNVGGSGLSKSRLYPQAQHSHYPHYSASATPNQSGGASEIQEL ASKRVDIQKKRFYLDVKQSSRGRFLKIAEVWIGRGRQDNIRKSKLTLSLSVAAELKDCLGDFIE HYAHLGLKGHRQEHGQSKEQVSRRRQKHSAPSPPVSVGSEEHPHSVLKTDYIERDNRKYYLDLK ENQRGRFLRIRQTMMRGTGMIGYFGHSLGQEQTIVLPAQGMIEFRDALVQLIEDYGEGDIEERR GGDDDPLELPEGTSFRVDNKRFYFDVGSNKYGIFLKLTNFPKSRENLNLFHCCQTKRKEQPHDT TNTVEE hide sequence

Ensembl Acc Id:

ENSRNOP00000020683 ⟸ ENSRNOT00000020683

Ensembl Acc Id:

ENSRNOP00000109748 ⟸ ENSRNOT00000134931

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZYS1-F1-model_v2	AlphaFold	D3ZYS1	1-351	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305088	AgrOrtholog
BioCyc Gene	G2FUF-11112	BioCyc
Ensembl Genes	ENSRNOG00000015426	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000020683.8	UniProtKB/TrEMBL
	ENSRNOT00000134931	ENTREZGENE
	ENSRNOT00000134931.1	UniProtKB/TrEMBL
Gene3D-CATH	3.10.450.700	UniProtKB/TrEMBL
	3.30.2450.30	UniProtKB/TrEMBL
InterPro	PUR_DNA_RNA-bd	UniProtKB/TrEMBL
KEGG Report	rno:361162	UniProtKB/TrEMBL
NCBI Gene	361162	ENTREZGENE
PANTHER	PTHR12611:SF3	UniProtKB/TrEMBL
	PUR_DNA_RNA_bd	UniProtKB/TrEMBL
Pfam	PurA	UniProtKB/TrEMBL
PhenoGen	Purg	PhenoGen
RatGTEx	ENSRNOG00000015426	RatGTEx
SMART	PUR	UniProtKB/TrEMBL
UniProt	A0ABK0LUE9_RAT	UniProtKB/TrEMBL
	A6IVT5	ENTREZGENE, UniProtKB/TrEMBL
	D3ZYS1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Purg	purine-rich element binding protein G	Purg_predicted	purine-rich element binding protein G (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Purg_predicted	purine-rich element binding protein G (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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