Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | increases expression | ISO | Trim69 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of TRIM69 mRNA | CTD | PMID:28189721 and PMID:28960355 | 17alpha-ethynylestradiol | increases expression | ISO | Trim69 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of TRIM69 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | Trim69 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TRIM69 mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | ISO | TRIM69 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of TRIM69 mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Trim69 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TRIM69 mRNA | CTD | PMID:17942748 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of TRIM69 mRNA | CTD | PMID:21346803 | 4-amino-2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 4-amino-2 and 6-dinitrotoluene affects the expression of TRIM69 mRNA | CTD | PMID:21346803 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of TRIM69 mRNA | CTD | PMID:31881176 | aflatoxin B1 | increases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of TRIM69 mRNA | CTD | PMID:21641981 | aldehydo-D-glucose | multiple interactions | ISO | Trim69 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of TRIM69 mRNA | CTD | PMID:37567420 | all-trans-retinoic acid | increases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of TRIM69 mRNA | CTD | PMID:33167477 | arsenite(3-) | multiple interactions | ISO | TRIM69 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to TRIM69 mRNA] | CTD | PMID:32406909 | avobenzone | decreases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | avobenzone results in decreased expression of TRIM69 mRNA | CTD | PMID:31016361 | benzo[a]pyrene | decreases methylation | ISO | TRIM69 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of TRIM69 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | TRIM69 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TRIM69 promoter | CTD | PMID:27901495 | bisphenol A | increases methylation | ISO | TRIM69 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of TRIM69 gene | CTD | PMID:22576693 | bisphenol A | decreases methylation | ISO | TRIM69 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of TRIM69 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TRIM69 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of TRIM69 mRNA | CTD | PMID:22576693 | CGP 52608 | multiple interactions | ISO | TRIM69 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TRIM69 gene] | CTD | PMID:28238834 | chloroacetaldehyde | increases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | chloroacetaldehyde results in increased expression of TRIM69 mRNA | CTD | PMID:25596134 | D-glucose | multiple interactions | ISO | Trim69 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of TRIM69 mRNA | CTD | PMID:37567420 | dioxygen | increases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | Oxygen deficiency results in increased expression of TRIM69 mRNA | CTD | PMID:25596134 | dorsomorphin | multiple interactions | ISO | TRIM69 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TRIM69 mRNA | CTD | PMID:29803840 | entinostat | increases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | entinostat results in increased expression of TRIM69 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | ISO | TRIM69 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TRIM69 mRNA | CTD | PMID:27188386 | ethylparaben | increases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in increased expression of TRIM69 mRNA | CTD | PMID:37690743 | fructose | multiple interactions | ISO | Trim69 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of TRIM69 mRNA | CTD | PMID:37567420 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of TRIM69 mRNA | CTD | PMID:25539665 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of TRIM69 mRNA | CTD | PMID:33387578 | glucose | multiple interactions | ISO | Trim69 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of TRIM69 mRNA | CTD | PMID:37567420 | lipopolysaccharide | increases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of TRIM69 mRNA | CTD | PMID:35811015 | lipopolysaccharide | multiple interactions | ISO | TRIM69 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of TRIM69 mRNA | CTD | PMID:35811015 | methcathinone | increases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | monomethylpropion results in increased expression of TRIM69 mRNA | CTD | PMID:22303338 | methylmercury chloride | increases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of TRIM69 mRNA | CTD | PMID:28001369 | nickel atom | increases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | Nickel results in increased expression of TRIM69 mRNA | CTD | PMID:24768652 and PMID:25583101 | panobinostat | multiple interactions | ISO | TRIM69 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TRIM69 mRNA | CTD | PMID:27188386 | panobinostat | increases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | panobinostat results in increased expression of TRIM69 mRNA | CTD | PMID:26272509 | paracetamol | affects expression | ISO | Trim69 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TRIM69 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of TRIM69 mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of TRIM69 mRNA | CTD | PMID:21420995 | phenylmercury acetate | increases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of TRIM69 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | TRIM69 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TRIM69 mRNA | CTD | PMID:27188386 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | TRIM69 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of TRIM69 mRNA | CTD | PMID:35811015 | SB 431542 | multiple interactions | ISO | TRIM69 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | increases expression | ISO | Trim69 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of TRIM69 mRNA | CTD | PMID:37682722 | sodium fluoride | increases expression | ISO | Trim69 (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of TRIM69 protein | CTD | PMID:28918527 | testosterone | increases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | Testosterone results in increased expression of TRIM69 mRNA | CTD | PMID:33359661 | trichostatin A | increases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of TRIM69 mRNA | CTD | PMID:24935251 | triclosan | decreases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of TRIM69 mRNA | CTD | PMID:30510588 | Triptolide | increases expression | ISO | Trim69 (Mus musculus) | 6480464 | triptolide results in increased expression of TRIM69 mRNA | CTD | PMID:32835833 | triptonide | increases expression | ISO | Trim69 (Mus musculus) | 6480464 | triptonide results in increased expression of TRIM69 mRNA | CTD | PMID:33045310 | valproic acid | increases expression | ISO | TRIM69 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TRIM69 mRNA | CTD | PMID:26272509 | valproic acid | multiple interactions | ISO | TRIM69 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TRIM69 mRNA | CTD | PMID:27188386 | |