Arhgap18 (Rho GTPase activating protein 18) - Rat Genome Database

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Gene: Arhgap18 (Rho GTPase activating protein 18) Rattus norvegicus
Analyze
Symbol: Arhgap18
Name: Rho GTPase activating protein 18
RGD ID: 1305053
Description: Predicted to enable GTPase activator activity. Predicted to be involved in several processes, including regulation of actin filament polymerization; regulation of small GTPase mediated signal transduction; and small GTPase-mediated signal transduction. Predicted to be located in cytoplasmic microtubule and ruffle. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human ARHGAP18 (Rho GTPase activating protein 18); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC293947; rho GTPase-activating protein 18
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8120,222,948 - 20,456,827 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl120,222,954 - 20,456,670 (-)EnsemblGRCr8
mRatBN7.2118,403,531 - 18,637,306 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl118,403,537 - 18,637,256 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx118,175,502 - 18,323,790 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0124,177,421 - 24,325,602 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0118,375,245 - 18,523,535 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0119,227,115 - 19,463,139 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl119,227,121 - 19,376,301 (-)Ensemblrn6Rnor6.0
Rnor_5.0120,730,426 - 20,964,110 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4118,967,836 - 19,116,268 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera116,806,860 - 16,954,243 (-)NCBICelera
RGSC_v3.1118,968,043 - 19,116,304 (-)NCBI
Cytogenetic Map1p12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
4-hydroxyphenyl retinamide  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzene  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chromium(6+)  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenamidone  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
furan  (EXP)
genistein  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
isoprenaline  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
melphalan  (ISO)
mercury dibromide  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylmercury(1+)  (EXP)
nickel sulfate  (ISO)
nitrofen  (EXP)
p-toluidine  (EXP)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sunitinib  (ISO)
T-2 toxin  (EXP)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vincristine  (ISO)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO)
cytoplasmic microtubule  (IEA,ISO)
cytosol  (IEA,ISO)
ruffle  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Gene discovery through imaging genetics: identification of two novel genes associated with schizophrenia. Potkin SG, etal., Mol Psychiatry. 2009 Apr;14(4):416-28. Epub 2008 Dec 9.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:21865595   PMID:25468996   PMID:28251925  


Genomics

Comparative Map Data
Arhgap18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8120,222,948 - 20,456,827 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl120,222,954 - 20,456,670 (-)EnsemblGRCr8
mRatBN7.2118,403,531 - 18,637,306 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl118,403,537 - 18,637,256 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx118,175,502 - 18,323,790 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0124,177,421 - 24,325,602 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0118,375,245 - 18,523,535 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0119,227,115 - 19,463,139 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl119,227,121 - 19,376,301 (-)Ensemblrn6Rnor6.0
Rnor_5.0120,730,426 - 20,964,110 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4118,967,836 - 19,116,268 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera116,806,860 - 16,954,243 (-)NCBICelera
RGSC_v3.1118,968,043 - 19,116,304 (-)NCBI
Cytogenetic Map1p12NCBI
ARHGAP18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386129,576,132 - 129,710,177 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6129,576,132 - 129,710,247 (-)Ensemblhg38GRCh38
GRCh376129,897,277 - 130,031,322 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366129,939,933 - 130,073,063 (-)NCBIBuild 36Build 36hg18NCBI36
Build 346129,939,933 - 130,073,063NCBI
Celera6130,644,627 - 130,777,755 (-)NCBICelera
Cytogenetic Map6q22.33NCBI
HuRef6127,478,880 - 127,611,993 (-)NCBIHuRef
CHM1_16130,161,897 - 130,295,089 (-)NCBICHM1_1
T2T-CHM13v2.06130,769,768 - 130,904,795 (-)NCBIT2T-CHM13v2.0
Arhgap18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391026,648,363 - 26,794,644 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1026,629,417 - 26,794,644 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381026,772,408 - 26,918,648 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1026,753,421 - 26,918,648 (+)Ensemblmm10GRCm38
MGSCv371026,492,318 - 26,638,454 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361026,461,928 - 26,608,064 (+)NCBIMGSCv36mm8
Celera1027,698,326 - 27,844,280 (+)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1014.12NCBI
Arhgap18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543610,470,123 - 10,587,159 (-)Ensembl
ChiLan1.0NW_00495543610,470,398 - 10,642,890 (-)NCBIChiLan1.0ChiLan1.0
ARHGAP18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25149,573,994 - 149,764,114 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16147,480,767 - 147,670,913 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06127,368,377 - 127,558,136 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16131,475,016 - 131,609,310 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6131,477,383 - 131,609,221 (-)EnsemblpanPan2panpan1.1
ARHGAP18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1168,143,702 - 68,262,440 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl168,143,702 - 68,275,022 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha168,891,798 - 69,009,879 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0168,355,278 - 68,474,150 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl168,355,274 - 68,474,187 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1168,278,032 - 68,396,913 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0168,059,453 - 68,177,740 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0168,704,723 - 68,823,568 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Arhgap18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946118,233,001 - 118,350,825 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493663968,348 - 186,172 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493663968,321 - 186,169 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl133,527,734 - 33,717,966 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1133,527,734 - 33,717,980 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2137,113,063 - 37,161,298 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGAP18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11343,825,469 - 44,015,655 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1343,880,459 - 44,018,036 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604015,985,469 - 16,182,349 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgap18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247533,851,699 - 3,971,796 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247533,854,364 - 4,034,307 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Arhgap18
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12212,787,390 - 212,934,430 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Arhgap18
1778 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:184
Count of miRNA genes:135
Interacting mature miRNAs:139
Transcripts:ENSRNOT00000015547
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1529322934184556Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1774611852746118Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1774612152746121Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)1143965634Rat
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1126564886Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)11037949255379492Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1694102251941022Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1529322934184556Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)1690935351909353Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11731537851816258Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1126564886Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)1690935351909353Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)1690935351909353Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11282049457820494Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)1134184556Rat
1300170Rf6Renal function QTL 63.14renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)1128483164Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)11168446456684464Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1529322934184556Rat

Markers in Region
D1Got22  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2118,513,222 - 18,513,426 (+)MAPPERmRatBN7.2
Rnor_6.0119,337,625 - 19,337,828NCBIRnor6.0
Rnor_5.0120,841,161 - 20,841,364UniSTSRnor5.0
RGSC_v3.4119,077,546 - 19,077,750RGDRGSC3.4
RGSC_v3.4119,077,547 - 19,077,750UniSTSRGSC3.4
Celera116,915,567 - 16,915,770UniSTS
RGSC_v3.1119,077,609 - 19,077,812RGD
RH 3.4 Map1178.7UniSTS
RH 3.4 Map1178.7RGD
RH 2.0 Map1118.3RGD
Cytogenetic Map1p12UniSTS
RH144405  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2118,529,496 - 18,529,688 (+)MAPPERmRatBN7.2
Rnor_6.0119,353,904 - 19,354,095NCBIRnor6.0
Rnor_5.0120,857,440 - 20,857,631UniSTSRnor5.0
RGSC_v3.4119,093,836 - 19,094,027UniSTSRGSC3.4
Celera116,931,846 - 16,932,037UniSTS
RH 3.4 Map1170.7UniSTS
Cytogenetic Map1p12UniSTS
BI291839  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2118,507,327 - 18,507,543 (+)MAPPERmRatBN7.2
Rnor_6.0119,331,732 - 19,331,947NCBIRnor6.0
Rnor_5.0120,835,268 - 20,835,483UniSTSRnor5.0
RGSC_v3.4119,071,654 - 19,071,869UniSTSRGSC3.4
Celera116,909,690 - 16,909,905UniSTS
RH 3.4 Map1169.7UniSTS
Cytogenetic Map1p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000015547   ⟹   ENSRNOP00000015548
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl120,222,954 - 20,371,296 (-)Ensembl
mRatBN7.2 Ensembl118,403,539 - 18,551,939 (-)Ensembl
Rnor_6.0 Ensembl119,227,121 - 19,376,301 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096976   ⟹   ENSRNOP00000087899
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl120,222,954 - 20,456,670 (-)Ensembl
mRatBN7.2 Ensembl118,403,537 - 18,637,256 (-)Ensembl
RefSeq Acc Id: NM_001170575   ⟹   NP_001164046
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8120,222,951 - 20,371,296 (-)NCBI
mRatBN7.2118,403,534 - 18,551,900 (-)NCBI
Rnor_6.0119,227,118 - 19,376,301 (-)NCBI
Rnor_5.0120,730,426 - 20,964,110 (-)NCBI
Celera116,806,860 - 16,954,243 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006227680   ⟹   XP_006227742
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8120,222,948 - 20,323,880 (-)NCBI
mRatBN7.2118,403,531 - 18,505,160 (-)NCBI
Rnor_6.0119,227,115 - 19,329,567 (-)NCBI
Rnor_5.0120,730,426 - 20,964,110 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017589037   ⟹   XP_017444526
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8120,222,948 - 20,456,827 (-)NCBI
mRatBN7.2118,403,531 - 18,637,306 (-)NCBI
Rnor_6.0119,227,115 - 19,463,139 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039108944   ⟹   XP_038964872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8120,266,859 - 20,371,348 (-)NCBI
mRatBN7.2118,447,366 - 18,551,934 (-)NCBI
RefSeq Acc Id: NP_001164046   ⟸   NM_001170575
- UniProtKB: F1LXP8 (UniProtKB/TrEMBL),   A6JPF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227742   ⟸   XM_006227680
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017444526   ⟸   XM_017589037
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A5D2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000015548   ⟸   ENSRNOT00000015547
RefSeq Acc Id: XP_038964872   ⟸   XM_039108944
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000087899   ⟸   ENSRNOT00000096976
Protein Domains
Rho-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LXP8-F1-model_v2 AlphaFold F1LXP8 1-665 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689520
Promoter ID:EPDNEW_R45
Type:initiation region
Name:Arhgap18_1
Description:Rho GTPase activating protein 18
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0119,376,275 - 19,376,335EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305053 AgrOrtholog
BioCyc Gene G2FUF-62156 BioCyc
Ensembl Genes ENSRNOG00000011245 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015547 ENTREZGENE
  ENSRNOT00000015547.8 UniProtKB/TrEMBL
  ENSRNOT00000096976 ENTREZGENE
  ENSRNOT00000096976.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
InterPro RHG40/28/18_ubiquitin UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
KEGG Report rno:293947 UniProtKB/TrEMBL
NCBI Gene 293947 ENTREZGENE
PANTHER RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED UniProtKB/TrEMBL
  RHO GTPASE-ACTIVATING PROTEIN 18 UniProtKB/TrEMBL
Pfam RhoGAP UniProtKB/TrEMBL
  Ubiquitin_RHG40_C UniProtKB/TrEMBL
PhenoGen Arhgap18 PhenoGen
PROSITE RHOGAP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011245 RatGTEx
SMART RhoGAP UniProtKB/TrEMBL
Superfamily-SCOP Rho_GAP UniProtKB/TrEMBL
UniProt A0A8I6A5D2 ENTREZGENE, UniProtKB/TrEMBL
  A6JPF6 ENTREZGENE, UniProtKB/TrEMBL
  F1LXP8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Arhgap18  Rho GTPase activating protein 18   Arhgap18_predicted  Rho GTPase activating protein 18 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Arhgap18_predicted  Rho GTPase activating protein 18 (predicted)      Symbol and Name status set to approved 70820 APPROVED