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Gene: Cebpz (CCAAT/enhancer binding protein zeta) Rattus norvegicus

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Symbol:

Cebpz

Name:

CCAAT/enhancer binding protein zeta

RGD ID:

1304994

Description:

Predicted to enable transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Part of CCAAT-binding activity factor complex. Orthologous to human CEBPZ (CCAAT enhancer binding protein zeta); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Cbf; CCAAT/enhancer-binding protein zeta; core-binding factor

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CEBPZ (CCAAT enhancer binding protein zeta)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Cebpz (CCAAT/enhancer binding protein zeta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cebpz (CCAAT enhancer binding protein zeta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CEBPZ (CCAAT enhancer binding protein zeta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CEBPZ (CCAAT enhancer binding protein zeta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cebpz (CCAAT enhancer binding protein zeta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CEBPZ (CCAAT enhancer binding protein zeta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CEBPZ (CCAAT enhancer binding protein zeta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cebpz (CCAAT enhancer binding protein zeta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Cebpz (CCAAT enhancer binding protein zeta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CEBPZ (CCAAT enhancer binding protein zeta)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Cebpz (CCAAT/enhancer binding protein zeta)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cebpz (CCAAT enhancer binding protein zeta)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG7839	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F23B12.7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	MAK21	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cebpz	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	21,872,071 - 21,889,755 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	21,872,025 - 21,889,749 (+)	Ensembl				GRCr8
mRatBN7.2	6	16,119,871 - 16,137,600 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	16,119,872 - 16,137,600 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	16,435,347 - 16,452,948 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	16,757,557 - 16,775,158 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	16,237,982 - 16,255,559 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	1,516,804 - 1,534,488 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	1,516,804 - 1,534,488 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	1,506,913 - 1,524,597 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	1,698,162 - 1,715,846 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	15,784,628 - 15,802,293 (+)	NCBI		Celera
RGSC_v3.1	6	1,699,016 - 1,715,835 (-)	NCBI
Cytogenetic Map	6	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin M1 (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsenous acid (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bucladesine (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

camptothecin (ISO)

chlorpyrifos (ISO)

cyclosporin A (ISO)

cyproconazole (ISO)

daunorubicin (ISO)

DDE (ISO)

diarsenic trioxide (ISO)

dicrotophos (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

epoxiconazole (ISO)

etoposide (ISO)

fluoranthene (ISO)

flutamide (EXP)

folic acid (ISO)

FR900359 (ISO)

gentamycin (EXP)

ivermectin (ISO)

medroxyprogesterone acetate (ISO)

N-nitrosodiethylamine (EXP)

ochratoxin A (EXP)

pirinixic acid (ISO)

propiconazole (ISO)

SB 431542 (ISO)

simvastatin (ISO)

sodium dichromate (EXP)

Soman (EXP)

temozolomide (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

tungsten (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA-templated transcription (IEA)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

Cellular Component

CCAAT-binding factor complex (IDA)

nucleoplasm (IEA,ISO)

nucleus (IBA,IEA,ISO)

Molecular Function

DNA binding (ISO)

protein binding (ISO)

transcription coactivator activity (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	The CCAAT-binding proteins CP1 and NF-I cooperate with ATF-2 in the transcription of the fibronectin gene.	Alonso CR, etal., J Biol Chem. 1996 Sep 6;271(36):22271-9. doi: 10.1074/jbc.271.36.22271.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Proteomics profiling of nuclear proteins for kidney fibroblasts suggests hypoxia, meiosis, and cancer may meet in the nucleus.	Shakib K, etal., Proteomics. 2005 Jul;5(11):2819-38.

Additional References at PubMed

PMID:2247079	PMID:14634060	PMID:22658674	PMID:22681889

Genomics

Comparative Map Data

Cebpz
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	21,872,071 - 21,889,755 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	21,872,025 - 21,889,749 (+)	Ensembl				GRCr8
mRatBN7.2	6	16,119,871 - 16,137,600 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	16,119,872 - 16,137,600 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	16,435,347 - 16,452,948 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	16,757,557 - 16,775,158 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	16,237,982 - 16,255,559 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	1,516,804 - 1,534,488 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	1,516,804 - 1,534,488 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	1,506,913 - 1,524,597 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	1,698,162 - 1,715,846 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	15,784,628 - 15,802,293 (+)	NCBI		Celera
RGSC_v3.1	6	1,699,016 - 1,715,835 (-)	NCBI
Cytogenetic Map	6	q12	NCBI

CEBPZ
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	37,201,612 - 37,231,596 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	37,201,570 - 37,231,601 (-)	Ensembl			hg38	GRCh38
GRCh37	2	37,428,755 - 37,458,739 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	37,282,276 - 37,312,244 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	37,340,427 - 37,370,391	NCBI
Celera	2	37,269,769 - 37,299,695 (-)	NCBI		Celera
Cytogenetic Map	2	p22.2	NCBI
HuRef	2	37,168,718 - 37,198,634 (-)	NCBI		HuRef
CHM1_1	2	37,358,225 - 37,388,174 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	37,208,702 - 37,238,637 (-)	NCBI		T2T-CHM13v2.0

Cebpz
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	79,226,432 - 79,244,499 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	79,226,435 - 79,244,495 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	78,919,003 - 78,937,070 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	78,919,006 - 78,937,066 (-)	Ensembl			mm10	GRCm38
MGSCv37	17	79,318,343 - 79,336,410 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	78,824,297 - 78,842,125 (-)	NCBI		MGSCv36	mm8
Celera	17	83,237,268 - 83,257,640 (-)	NCBI		Celera
Cytogenetic Map	17	E3	NCBI
cM Map	17	49.65	NCBI

Cebpz
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955441	5,013,144 - 5,033,830 (-)	Ensembl
ChiLan1.0	NW_004955441	5,013,144 - 5,033,830 (-)	NCBI	ChiLan1.0	ChiLan1.0

CEBPZ
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	89,248,010 - 89,276,867 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	89,251,994 - 89,280,843 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	37,230,245 - 37,259,113 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	37,995,123 - 38,023,965 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	37,995,123 - 38,023,965 (-)	Ensembl			panPan2	panpan1.1

CEBPZ
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	29,565,712 - 29,584,789 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	29,565,722 - 29,584,874 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	29,379,352 - 29,398,593 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	30,215,309 - 30,234,551 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	30,215,214 - 30,234,495 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	29,442,642 - 29,461,854 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	29,505,770 - 29,525,454 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	29,723,995 - 29,743,236 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Cebpz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	42,396,743 - 42,416,376 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936663	1,061,472 - 1,086,020 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936663	1,062,248 - 1,081,598 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CEBPZ
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	102,964,240 - 102,989,243 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	102,964,213 - 102,988,664 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	109,397,935 - 109,422,194 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CEBPZ
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	70,161,111 - 70,189,757 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	70,161,155 - 70,190,506 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666045	41,759,168 - 41,786,928 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cebpz
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624738	18,819,428 - 18,836,468 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624738	18,819,238 - 18,836,517 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Cebpz
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	7	14,296,383 - 14,313,314 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Cebpz
109 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	241
Count of miRNA genes:	166
Interacting mature miRNAs:	185
Transcripts:	ENSRNOT00000006824
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8552962	Pigfal16	Plasma insulin-like growth factor 1 level QTL 16	9.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	1975879	46975879	Rat
7411603	Foco13	Food consumption QTL 13	5.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1975879	46975879	Rat
1598843	Cm63	Cardiac mass QTL 63	2.6		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	1	44788383	Rat
7411542	Bw127	Body weight QTL 127	5.5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	1975879	46975879	Rat
8693699	Alc37	Alcohol consumption QTL 37	2.6	0.224	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	6	13717169	27053860	Rat
2293706	Bmd20	Bone mineral density QTL 20	4.3	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	6	1	25740059	Rat
2292616	Ept15	Estrogen-induced pituitary tumorigenesis QTL 15	4.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	6	1	44788383	Rat
9589048	Scfw3	Subcutaneous fat weight QTL 3	4.57	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	6	1975879	46975879	Rat
10401812	Kidm54	Kidney mass QTL 54			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	20097635	65097635	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	20859430	113082285	Rat
2301964	Bp323	Blood pressure QTL 323	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	86868070	Rat
2293709	Bss23	Bone structure and strength QTL 23	5.18	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	6	3239989	48239989	Rat
2293650	Bss31	Bone structure and strength QTL 31	5.05	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	6	3239989	48239989	Rat
1300128	Rf16	Renal function QTL 16	3.89		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	1	40163351	Rat
70199	Coreg1	Compensatory renal growth QTL 1	11.8		kidney mass (VT:0002707)	compensatory renal growth score (CMO:0001894)	6	14599473	63457687	Rat
10401800	Kidm49	Kidney mass QTL 49			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	20097635	65097635	Rat
1300164	Rf15	Renal function QTL 15	3.12		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	3239989	48239989	Rat
2301972	Bp325	Blood pressure QTL 325	4.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	16089372	61967788	Rat
1358190	Ept1	Estrogen-induced pituitary tumorigenesis QTL 1	4.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	6	1	44788383	Rat
2293656	Bss28	Bone structure and strength QTL 28	6.79	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	6	3239989	48239989	Rat
9589129	Insul24	Insulin level QTL 24	19.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	6	1975879	46975879	Rat
8693690	Alc35	Alcohol consumption QTL 35	2.2	0.606	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	6	13717169	27053860	Rat

Markers in Region

RH128770

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	16,135,597 - 16,135,749 (-)	MAPPER	mRatBN7.2
Rnor_6.0	6	1,518,655 - 1,518,806	NCBI	Rnor6.0
Rnor_5.0	6	1,508,764 - 1,508,915	UniSTS	Rnor5.0
RGSC_v3.4	6	1,700,013 - 1,700,164	UniSTS	RGSC3.4
Celera	6	15,800,291 - 15,800,442	UniSTS
Cytogenetic Map	6	q11	UniSTS

RH137911

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	16,127,151 - 16,127,313 (-)	MAPPER	mRatBN7.2
Rnor_6.0	6	1,527,091 - 1,527,252	NCBI	Rnor6.0
Rnor_5.0	6	1,517,200 - 1,517,361	UniSTS	Rnor5.0
RGSC_v3.4	6	1,708,449 - 1,708,610	UniSTS	RGSC3.4
Celera	6	15,791,864 - 15,792,025	UniSTS
Cytogenetic Map	6	q11	UniSTS

Expression

RNA-SEQ Expression

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alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108701	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112455	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217457	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221797	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223432	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ225023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006824 ⟹ ENSRNOP00000006824

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	21,872,025 - 21,889,749 (+)	Ensembl
mRatBN7.2 Ensembl	6	16,119,916 - 16,137,600 (+)	Ensembl
Rnor_6.0 Ensembl	6	1,516,804 - 1,534,488 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107193 ⟹ ENSRNOP00000097393

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	21,872,025 - 21,889,749 (+)	Ensembl
mRatBN7.2 Ensembl	6	16,119,872 - 16,136,866 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118242 ⟹ ENSRNOP00000094929

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	21,872,025 - 21,889,749 (+)	Ensembl
mRatBN7.2 Ensembl	6	16,119,916 - 16,137,600 (+)	Ensembl

RefSeq Acc Id:

NM_001108701 ⟹ NP_001102171

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	21,872,071 - 21,889,755 (+)	NCBI
mRatBN7.2	6	16,119,916 - 16,137,600 (+)	NCBI
Rnor_6.0	6	1,516,804 - 1,534,488 (-)	NCBI
Rnor_5.0	6	1,506,913 - 1,524,597 (-)	NCBI
RGSC_v3.4	6	1,698,162 - 1,715,846 (-)	RGD
Celera	6	15,784,628 - 15,802,293 (+)	RGD

Sequence:

show sequence

TCCAGCCTACAATGTCGGCGGACCAGGAACCTTTAGAGTTCCTTGCCAAGAATCCCTGGCGTCC
CAAAGAGGTGACAGAAGATCCAGACGAGGAAGACGAGGAGGATAGCGATGAGGCCAAGAATGGC
TTCTCTCTGGAGGAGGTGTTACGCCTCGGAGGCACGAAGCAAGATTACCTTATGCTGGCTACTT
TGGATGAAAATGAAGAAGTAGTAGATGGAGGCAAAAAGGGAACCATCGACGACCTCCAACAAGG
TGAATTGGAGGCATTTATTCAGAATCTGAATTTGGCCAAATACTCGAAGTCTCTGATTGAAGAG
GATGAACCAGAGAAAAAAGAAAACACCAGCAAAAAAGAAGCAAAACTACCGAAGGTAGAGAATA
AGAAACAGAAAGCAGCAGAAGGAAAAAAGAAAAATAAAAGCGTACCAGAGCAGCATCCCGAGAG
CAGTACCGTCTTCAAAGCGAAGAGGGATAAACAGCCCGATGCATTCGAATTTCTAGAGAGACAG
GCGCTGTTACTCAAGCCTGGGGGCAAGTGGTACGACATGGAATACAGCGGTGAGTTTTCCTTGG
AACCACAGCCTTGGGATGTAGTGTCCAAGTACAAAGCCCTGGCCGAGAAGCTGTACGAGCAGGA
AGTCGGCTTATTCAAGAATAAGACAAGCAATCAAAAGGGAGGCTCCTCCACCTGGATGAAGGCA
ATCGTGTCATCGGGGACGCTAGCCGACAGGATGGCAGCCATGATCCTTCTGATCCAGGATGACG
CTGTTCACACACTCCAGTTTGTAGAAACCCTCTTGAGCCTTGTTAGAAAGAAGGGCAGCAAGCA
GCAGTGCCTCATGGCTTTGGATACGTTCAAGGAGCTGCTCATCACCGACCTTCTTCCGGACAGT
CGGAAGCTCCGGCTCTTCAGCCAGCGCCCCCTTCACAAACTGGAAGAGCTGTCCAGTGGCAACA
AGGACTCAAGAGATAGAAGACTGATCCTGTGGTATTACGAGCACCAACTGAAGCACTTGGTAGC
AGAATTTGTTCAGGTCCTCGAGACTTTAAGTCACGATTCCCTGGTAACCACCAAAACCCGAGCC
CTGGTAGCGGCCCATGAGCTTCTCTGTGATAAACCCGAGGAGGAAAAGGCTCTTCTTGTGCAGG
TGATAAATAAGCTGGGAGACCCTCAGAACAGAATCGCCACCAAAGCTTCCCATCTGCTAGAAGT
GTTGCTGCGGAAGCATCCCAATATGAAGGGAGTCGTGTGTGGAGAACTAGAACGGCTACTCTTT
CGCTCAAATATCAGCCCCAAAGCTCAGTATTATGCAATTTGCTTTTTAAACCAAATGGTCCTCT
CCCATGAAGAAAGTGAGCTGGCTAACAAATTAATAACTCTTTATTTTTGTTTCTTTCGGACTTG
TATCAAGAAAAAAGACATTGAATCAAAAATGCTCAGTGCCATTTTAACAGGCGTGAACAGAGCG
TACCCTTACTCCCAGATAGGTGACGACAGAGTGAGGGAGCAGGTGGACACTTTATTCAAAGTGT
TGCATGTTGTAAATTTTAATACTAGTGTGCAGGCTTTAATGCTACTTTTCCAGGTAATGAATTC
TCAGCAGACAATATCTGACCGATACTACACAGCTTTATACAAAAAGATGTTAGATCCGGGGTTG
ACGACATGTTCCAAGCAAGCGATGTTTCTTAACCTGATCTACAAATCTTTGAAAGCTGACATCA
TGCTACGCCGGGTGAAGGCTTTTGTGAAGAGGTTACTTCAGGTTACCTGCACACAGATGCCACC
ATTCATTTGTGGAGCCTTATATCTTGTGTCTGAGATTCTTAAAGCAAAACCAGATTTAAGAAGC
CAGCTAGATGATCATCCGGAATCTGATGAAGAAAACTTCGTTGACGTGGGAGATGACAGTGACG
ATGAAAAGTTTACCGATGCAGACAGAGAAACAGCAACAGATGCGGTGGAGGAAGTGGAGGCGAA
GGAGGCTGAGCCTGAGAGCAGCACAGAAACCGAGAAGCCGAAGGCTGCTTCCTGGGTGCACTTT
GACAATTTGAAAGGTGGCAAGCAGATAAAGACATATGATCCATTCAGTAGAAATCCTTTATTCT
GTGGAGCTGAACATACAAATCTTTGGGAGCTCAGAAAGCTATCTGAACATTTCCACCCTTCTGT
GGCCCTCTTTGCAAAGACTATCCTTGAGGGAAATCACATTCAGTATTCAGGGGACCCACTGCAG
GATTTCACACTCATGAGATTCCTGGACCGATTTGTATACCGAAATCCAAAGCTACATAAAGGCA
AAGAAAATACCGACAGCGTGGTGATGCAACCCAAAAGGAAGCACTTTATGAAGAATGTGCGGGA
TCTTGCTGTGAATAGTAAAGAGTTCCTTGCAAAAGAAGAAAGCCAGATCCCAGTGGATGAAGTG
TTCTTCTACAGGTATTACAAAAAAGTTGCTGTCACTAAAGACAAACAGAAACGGAATGCAGATG
AAGACAGTATAGAAGATGTTGATGATGAAGAATTTGAAAATATGATTGACACATTTGAAGATGA
CAACTGCTTCACGCCTGGAAAGGATGATATGGATTTTGCCAGTAATATGAAAAAAATAAAAGGA
GCTAAAGATGACTTGGAAGACTCGGAGAGCAGTGACGATGAGCTCGGTGACCTGGATGACGACG
AGGTCTCCCTAGGAAGTATGAATGATGAAGACTTTGAAATTGATGAAGATGGAGGAACATTCAT
GGATGTGTCAGATGACGAAAGTGACCATGTTCCAGAATTTGGTGAAGCCAGCCCCAAAGCCAGT
ACTAAGAAAAGCAAGAGGAAGAGTGAAGATGATTTTGACTTTGCTGGGTCATTTCAAGGACAAA
AGAAAAAGAAGAAAAGTTTCAATGACTCCAGCCTGTTTGTCTCTGCTGAAGAGTTTGGTCATCT
GTTGGATGAAAATATGGGCTCCAAGTTTGATACGACTGGCATGAACGCCATGGCTAACAAAGAC
AATGCAAGTTTCAAACAGCTCAAGTGGGAAGCTGAGCGTGATGATTGGCTCCACAACAGAGATG
TGAAAAGTATCATCAAGAAAAAGAAGAATTTCAGGAAAAAGAAAGCCCCTCAGAAACCCAAAAG
ACAAAGGAAGTGACAGCGTCAGAGTGAATAATAAGTTAAGATCATACTTACCCTTAATTTTTGC
TATCCAACCATTTTTGCTGATCTTTTTCTCTAACCCCATACATTCCAGACTGTTCAATGGATTT
GTAATAAACTGTGGAAACAAGGTGCTGTCATTTATACAATTATGATAAAGTTAAACTTATATTG
AAAAAATTCTTCCATATTACTTCATAACAATGAAAGGGACAGCAGGGCTCCTTCCCTGCTCGAG
CTGTAACCACTCTCCTGACCACTGGGAGCTGCTTGTTGAGGCACCGGGTGCCATGCTTAAGTTA
GGTACATGACGTCATTGTGGTCAACTCTTAACTGTCCAGGTAGGCACTGGCTCTTCCCCAGAGA
AAGCAGCATCTCTGAGAACACAGCCTTTTACAGCAGTAACTGGTTTGTGCCCATCCCCATCTTA
GGTCTCACTCTGGAATCTGTTCTTAACCACTGAGAGAATTAAAACTCCAGTTTGCAGGGTGGGG
TAAATAATAACTTTTGTGGGGTATTTGTAAAGTCTGAAAGTTAATTAATAAAAAAGGTAATGAG
GATTAAAACAAGAGCTAACTGTTCTCATCTAAGTAATTAGGTGTGAGTCCCTACTATGTGGTCC
CAGGAGGCAACTAGTGTCAGAAAATAATAACAAAATAATGTCACTTGCTCTAAAGTTGTAAAGT
ACCACAGAGTTTATAGGTTATTTTACACTTGAATTTTTACTTGAGAAAAAACATACCTTCCAAA
ATGAAGGGAAATGTCTTGCTCATTGTTTGCCTGAAATCTGATATTTAAAAAAAAAAAAAAAAAA
ACACTGTATTAACATATTAAACCACAATTTAATAAT

hide sequence

RefSeq Acc Id:

XM_039112455 ⟹ XP_038968383

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	21,872,082 - 21,876,884 (+)	NCBI
mRatBN7.2	6	16,119,871 - 16,124,727 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102171	(Get FASTA)	NCBI Sequence Viewer
	XP_038968383	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM02802	(Get FASTA)	NCBI Sequence Viewer
	EDM02803	(Get FASTA)	NCBI Sequence Viewer
	EDM02804	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006824
	ENSRNOP00000006824.4
	ENSRNOP00000094929.1
	ENSRNOP00000097393.1

RefSeq Acc Id:

NP_001102171 ⟸ NM_001108701

- UniProtKB:

A6H9U7 (UniProtKB/TrEMBL), D3ZNU1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSADQEPLEFLAKNPWRPKEVTEDPDEEDEEDSDEAKNGFSLEEVLRLGGTKQDYLMLATLDEN
EEVVDGGKKGTIDDLQQGELEAFIQNLNLAKYSKSLIEEDEPEKKENTSKKEAKLPKVENKKQK
AAEGKKKNKSVPEQHPESSTVFKAKRDKQPDAFEFLERQALLLKPGGKWYDMEYSGEFSLEPQP
WDVVSKYKALAEKLYEQEVGLFKNKTSNQKGGSSTWMKAIVSSGTLADRMAAMILLIQDDAVHT
LQFVETLLSLVRKKGSKQQCLMALDTFKELLITDLLPDSRKLRLFSQRPLHKLEELSSGNKDSR
DRRLILWYYEHQLKHLVAEFVQVLETLSHDSLVTTKTRALVAAHELLCDKPEEEKALLVQVINK
LGDPQNRIATKASHLLEVLLRKHPNMKGVVCGELERLLFRSNISPKAQYYAICFLNQMVLSHEE
SELANKLITLYFCFFRTCIKKKDIESKMLSAILTGVNRAYPYSQIGDDRVREQVDTLFKVLHVV
NFNTSVQALMLLFQVMNSQQTISDRYYTALYKKMLDPGLTTCSKQAMFLNLIYKSLKADIMLRR
VKAFVKRLLQVTCTQMPPFICGALYLVSEILKAKPDLRSQLDDHPESDEENFVDVGDDSDDEKF
TDADRETATDAVEEVEAKEAEPESSTETEKPKAASWVHFDNLKGGKQIKTYDPFSRNPLFCGAE
HTNLWELRKLSEHFHPSVALFAKTILEGNHIQYSGDPLQDFTLMRFLDRFVYRNPKLHKGKENT
DSVVMQPKRKHFMKNVRDLAVNSKEFLAKEESQIPVDEVFFYRYYKKVAVTKDKQKRNADEDSI
EDVDDEEFENMIDTFEDDNCFTPGKDDMDFASNMKKIKGAKDDLEDSESSDDELGDLDDDEVSL
GSMNDEDFEIDEDGGTFMDVSDDESDHVPEFGEASPKASTKKSKRKSEDDFDFAGSFQGQKKKK
KSFNDSSLFVSAEEFGHLLDENMGSKFDTTGMNAMANKDNASFKQLKWEAERDDWLHNRDVKSI
IKKKKNFRKKKAPQKPKRQRK

hide sequence

Ensembl Acc Id:

ENSRNOP00000006824 ⟸ ENSRNOT00000006824

RefSeq Acc Id:	XP_038968383 ⟸ XM_039112455
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000097393 ⟸ ENSRNOT00000107193

Ensembl Acc Id:

ENSRNOP00000094929 ⟸ ENSRNOT00000118242

Protein Domains

CCAAT-binding factor

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZNU1-F1-model_v2	AlphaFold	D3ZNU1	1-1045	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694355

Promoter ID:

EPDNEW_R4880

Type:

initiation region

Name:

Cebpz_1

Description:

CCAAT/enhancer binding protein zeta

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	1,534,514 - 1,534,574	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304994	AgrOrtholog
BioCyc Gene	G2FUF-38494	BioCyc
Ensembl Genes	ENSRNOG00000005087	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006824	ENTREZGENE
	ENSRNOT00000006824.7	UniProtKB/TrEMBL
	ENSRNOT00000107193.2	UniProtKB/TrEMBL
	ENSRNOT00000118242.2	UniProtKB/TrEMBL
InterPro	ARM-type_fold	UniProtKB/TrEMBL
	CCAAT-binding_factor	UniProtKB/TrEMBL
	CEBPZ/Mak21-like	UniProtKB/TrEMBL
KEGG Report	rno:362686	UniProtKB/TrEMBL
NCBI Gene	362686	ENTREZGENE
PANTHER	CCAAT/ENHANCER-BINDING PROTEIN ZETA	UniProtKB/TrEMBL
	PTHR12048	UniProtKB/TrEMBL
Pfam	CBF	UniProtKB/TrEMBL
PhenoGen	Cebpz	PhenoGen
RatGTEx	ENSRNOG00000005087	RatGTEx
Superfamily-SCOP	ARM-type_fold	UniProtKB/TrEMBL
UniProt	A0A8I6ASJ7_RAT	UniProtKB/TrEMBL
	A0A8I6AUW9_RAT	UniProtKB/TrEMBL
	A6H9U7	ENTREZGENE, UniProtKB/TrEMBL
	D3ZNU1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Cebpz	CCAAT/enhancer binding protein zeta	Cebpz_predicted	CCAAT/enhancer binding protein zeta (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Cebpz_predicted	CCAAT/enhancer binding protein zeta (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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