Ddx17 (DEAD-box helicase 17) - Rat Genome Database

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Gene: Ddx17 (DEAD-box helicase 17) Rattus norvegicus
Analyze
Symbol: Ddx17
Name: DEAD-box helicase 17
RGD ID: 1304945
Description: Predicted to enable several functions, including RNA binding activity; RNA helicase activity; and transcription coactivator activity. Predicted to be involved in several processes, including RNA metabolic process; nuclear receptor-mediated steroid hormone signaling pathway; and regulation of RNA metabolic process. Predicted to be located in nuclear speck. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human DDX17 (DEAD-box helicase 17); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DEAD (Asp-Glu-Ala-Asp) box helicase 17; DEAD (Asp-Glu-Ala-Asp) box polypeptide 17; LOC315133; MGC109323; probable ATP-dependent RNA helicase DDX17
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,971,522 - 112,989,747 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7112,971,523 - 112,989,747 (-)EnsemblGRCr8
mRatBN7.27111,091,127 - 111,109,353 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7111,089,445 - 111,109,193 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7112,838,716 - 112,856,990 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07115,062,251 - 115,080,524 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07115,031,624 - 115,049,898 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,761,843 - 120,765,012 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,761,826 - 120,780,641 (-)Ensemblrn6Rnor6.0
Rnor_5.07120,754,842 - 120,758,011 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47117,552,040 - 117,554,887 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7107,422,522 - 107,425,390 (-)NCBICelera
RGSC_v3.17117,570,607 - 117,591,584 (+)NCBI
Cytogenetic Map7q34NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-pinene  (ISO)
amiodarone  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chloroacetaldehyde  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
coumarin  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dimethylarsinous acid  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
fenthion  (ISO)
fenvalerate  (EXP)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furan  (EXP)
geldanamycin  (ISO)
gentamycin  (EXP)
graphene oxide  (ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
ifosfamide  (ISO)
indometacin  (ISO)
inulin  (ISO)
irinotecan  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
metformin  (EXP)
methamphetamine  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (EXP)
nickel atom  (EXP)
nickel dichloride  (ISO)
nickel sulfate  (EXP)
nicotine  (ISO)
nimesulide  (EXP)
nitrates  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
pirinixic acid  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone enanthate  (ISO)
tetraphene  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
Triptolide  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
nuclear speck  (IEA,ISO)
nucleus  (IBA,IEA,ISO)
ribonucleoprotein complex  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15632090   PMID:17011493   PMID:17226766   PMID:19946888   PMID:22658674   PMID:22681889   PMID:23022728   PMID:24275493   PMID:24910439   PMID:27478153   PMID:28131823  
PMID:30622218  


Genomics

Comparative Map Data
Ddx17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,971,522 - 112,989,747 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7112,971,523 - 112,989,747 (-)EnsemblGRCr8
mRatBN7.27111,091,127 - 111,109,353 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7111,089,445 - 111,109,193 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7112,838,716 - 112,856,990 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07115,062,251 - 115,080,524 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07115,031,624 - 115,049,898 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,761,843 - 120,765,012 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,761,826 - 120,780,641 (-)Ensemblrn6Rnor6.0
Rnor_5.07120,754,842 - 120,758,011 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47117,552,040 - 117,554,887 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7107,422,522 - 107,425,390 (-)NCBICelera
RGSC_v3.17117,570,607 - 117,591,584 (+)NCBI
Cytogenetic Map7q34NCBI
DDX17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382238,483,438 - 38,506,311 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2238,483,438 - 38,507,660 (-)Ensemblhg38GRCh38
GRCh372238,879,443 - 38,902,316 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,209,389 - 37,232,291 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342237,203,942 - 37,209,466NCBI
Celera2222,685,022 - 22,707,930 (-)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2221,845,483 - 21,868,386 (-)NCBIHuRef
CHM1_12238,838,236 - 38,861,132 (-)NCBICHM1_1
T2T-CHM13v2.02238,947,707 - 38,970,570 (-)NCBIT2T-CHM13v2.0
Ddx17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391579,411,897 - 79,430,976 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1579,411,937 - 79,430,942 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381579,527,696 - 79,546,764 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1579,527,736 - 79,546,741 (-)Ensemblmm10GRCm38
MGSCv371579,358,126 - 79,377,171 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361579,354,991 - 79,373,814 (-)NCBIMGSCv36mm8
Celera1581,652,214 - 81,671,297 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.77NCBI
Ddx17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541324,646,320 - 24,664,614 (-)Ensembl
ChiLan1.0NW_00495541324,646,317 - 24,664,614 (-)NCBIChiLan1.0ChiLan1.0
DDX17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22348,339,405 - 48,363,355 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12251,030,869 - 51,055,784 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02219,398,801 - 19,421,587 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12237,218,884 - 37,241,430 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2237,218,884 - 37,241,425 (-)EnsemblpanPan2panpan1.1
DDX17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11026,282,592 - 26,303,128 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1026,282,598 - 26,301,633 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1026,237,306 - 26,258,327 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01027,073,043 - 27,094,074 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,072,471 - 27,094,071 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11026,794,780 - 26,815,505 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,105,990 - 27,127,019 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01027,282,715 - 27,303,747 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ddx17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049459,796,194 - 9,815,657 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364922,806,516 - 2,827,181 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364922,806,630 - 2,826,071 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDX17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl59,485,702 - 9,505,157 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.159,485,792 - 9,505,157 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.256,766,508 - 6,783,741 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DDX17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11921,145,576 - 21,167,091 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1921,145,417 - 21,167,543 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666045104,598,872 - 104,623,267 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddx17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247529,602,447 - 9,620,575 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247529,602,267 - 9,620,770 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Ddx17
119 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:336
Count of miRNA genes:193
Interacting mature miRNAs:224
Transcripts:ENSRNOT00000075011
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)792388565119280177Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)782111245123048330Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)771621154114982716Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)773618702118618702Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
631201Panci1Pancreas inflammation QTL 100.001pancreas integrity trait (VT:0010560)percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)773557047118557047Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)782111245123048330Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)796700404118618702Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7110725024135371468Rat
10450862Kidm55Kidney mass QTL 554.9kidney mass (VT:0002707)kidney weight (CMO:0000081)772725037117725037Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
10450856Livw4Liver weight QTL 43.8liver mass (VT:0003402)liver weight (CMO:0000092)772725037117725037Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)778682549123682549Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)771621154119349044Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
15.MHAa64f3.seq  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27111,116,731 - 111,116,901 (+)MAPPERmRatBN7.2
Rnor_6.07120,787,766 - 120,787,935NCBIRnor6.0
Rnor_5.07120,780,765 - 120,780,934UniSTSRnor5.0
RGSC_v3.47117,528,657 - 117,528,826UniSTSRGSC3.4
Celera7107,448,144 - 107,448,313UniSTS
Cytogenetic Map7q34UniSTS
RH127676  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27111,089,215 - 111,089,403 (+)MAPPERmRatBN7.2
Rnor_6.07120,759,914 - 120,760,101NCBIRnor6.0
Rnor_5.07120,752,913 - 120,753,100UniSTSRnor5.0
RGSC_v3.47117,556,629 - 117,556,816UniSTSRGSC3.4
Celera7107,420,593 - 107,420,780UniSTS
RH 3.4 Map7850.2UniSTS
Cytogenetic Map7q34UniSTS
C80929  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27111,089,683 - 111,089,932 (+)MAPPERmRatBN7.2
Rnor_6.07120,760,382 - 120,760,630NCBIRnor6.0
Rnor_5.07120,753,381 - 120,753,629UniSTSRnor5.0
RGSC_v3.47117,556,100 - 117,556,348UniSTSRGSC3.4
Celera7107,421,061 - 107,421,309UniSTS
Cytogenetic Map7q34UniSTS
AA819656  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27111,089,686 - 111,089,932 (+)MAPPERmRatBN7.2
Rnor_6.07120,760,385 - 120,760,630NCBIRnor6.0
Rnor_5.07120,753,384 - 120,753,629UniSTSRnor5.0
RGSC_v3.47117,556,100 - 117,556,345UniSTSRGSC3.4
Celera7107,421,064 - 107,421,309UniSTS
RH 3.4 Map7857.0UniSTS
Cytogenetic Map7q34UniSTS
BM387078  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr87112,980,901 - 112,981,180 (+)Marker Load Pipeline
mRatBN7.27111,100,507 - 111,100,786 (+)MAPPERmRatBN7.2
Rnor_6.07120,771,543 - 120,771,821NCBIRnor6.0
Rnor_5.07120,764,542 - 120,764,820UniSTSRnor5.0
RGSC_v3.47117,544,726 - 117,545,004UniSTSRGSC3.4
Celera7107,431,921 - 107,432,199UniSTS
RH 3.4 Map7857.8UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000018185   ⟹   ENSRNOP00000018185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7112,971,523 - 112,989,747 (-)Ensembl
mRatBN7.2 Ensembl7111,089,462 - 111,109,187 (-)Ensembl
Rnor_6.0 Ensembl7120,762,256 - 120,780,108 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000075011
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7112,975,170 - 112,989,747 (-)Ensembl
mRatBN7.2 Ensembl7111,089,445 - 111,109,193 (-)Ensembl
Rnor_6.0 Ensembl7120,761,843 - 120,765,012 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076164   ⟹   ENSRNOP00000067910
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7111,089,462 - 111,106,438 (-)Ensembl
Rnor_6.0 Ensembl7120,761,826 - 120,780,641 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076397   ⟹   ENSRNOP00000068037
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7120,763,674 - 120,764,540 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076497
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7120,762,474 - 120,765,842 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076915
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7120,768,450 - 120,771,815 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000077000   ⟹   ENSRNOP00000068292
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7120,762,719 - 120,770,435 (-)Ensembl
RefSeq Acc Id: NM_001015018   ⟹   NP_001015018
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,971,522 - 112,975,073 (-)NCBI
mRatBN7.27111,091,127 - 111,094,678 (-)NCBI
Rnor_6.07120,761,843 - 120,765,012 (-)NCBI
Rnor_5.07120,754,842 - 120,758,011 (-)NCBI
RGSC_v3.47117,552,040 - 117,554,887 (+)RGD
Celera7107,422,522 - 107,425,390 (-)RGD
Sequence:
RefSeq Acc Id: NM_001372136   ⟹   NP_001359065
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,971,522 - 112,989,747 (-)NCBI
mRatBN7.27111,091,127 - 111,109,353 (-)NCBI
RefSeq Acc Id: NP_001015018   ⟸   NM_001015018
- Peptide Label: isoform 2
- UniProtKB: Q568Z8 (UniProtKB/TrEMBL),   A6HSS5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018185   ⟸   ENSRNOT00000018185
Ensembl Acc Id: ENSRNOP00000068292   ⟸   ENSRNOT00000077000
Ensembl Acc Id: ENSRNOP00000068037   ⟸   ENSRNOT00000076397
Ensembl Acc Id: ENSRNOP00000067910   ⟸   ENSRNOT00000076164
RefSeq Acc Id: NP_001359065   ⟸   NM_001372136
- Peptide Label: isoform 1
- UniProtKB: E9PT29 (UniProtKB/TrEMBL),   A6HSS3 (UniProtKB/TrEMBL),   A0A096MIX2 (UniProtKB/TrEMBL)
Protein Domains
DEAD-box RNA helicase Q   Helicase ATP-binding   Helicase C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A096MIX2-F1-model_v2 AlphaFold A0A096MIX2 1-652 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304945 AgrOrtholog
BioCyc Gene G2FUF-32757 BioCyc
Ensembl Genes ENSRNOG00000051170 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018185 ENTREZGENE
  ENSRNOT00000018185.9 UniProtKB/TrEMBL
  ENSRNOT00000075011.4 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro DDX17_ATP-bd-dom UniProtKB/TrEMBL
  DEAD/DEAH_box_helicase_dom UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RNA-helicase_DEAD-box_CS UniProtKB/TrEMBL
  RNA_helicase_DEAD_Q_motif UniProtKB/TrEMBL
KEGG Report rno:315133 UniProtKB/TrEMBL
NCBI Gene 315133 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE DBP3 UniProtKB/TrEMBL
Pfam DEAD UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
PhenoGen Ddx17 PhenoGen
PROSITE DEAD_ATP_HELICASE UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
  Q_MOTIF UniProtKB/TrEMBL
RatGTEx ENSRNOG00000051170 RatGTEx
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A096MIX2 ENTREZGENE
  A0A8I6ARR6_RAT UniProtKB/TrEMBL
  A6HSS3 ENTREZGENE, UniProtKB/TrEMBL
  A6HSS4_RAT UniProtKB/TrEMBL
  A6HSS5 ENTREZGENE, UniProtKB/TrEMBL
  E9PT29 ENTREZGENE, UniProtKB/TrEMBL
  Q568Z8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-13 Ddx17  DEAD-box helicase 17  Ddx17  DEAD (Asp-Glu-Ala-Asp) box helicase 17  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-01 Ddx17  DEAD (Asp-Glu-Ala-Asp) box helicase 17  Ddx17  DEAD (Asp-Glu-Ala-Asp) box polypeptide 17  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ddx17  DEAD (Asp-Glu-Ala-Asp) box polypeptide 17  Ddx17_predicted  DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ddx17_predicted  DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 (predicted)      Symbol and Name status set to approved 70820 APPROVED