Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Phf3 | Rat | (S)-nicotine | increases expression | ISO | PHF3 (Homo sapiens) | 6480464 | Nicotine results in increased expression of PHF3 mRNA | CTD | PMID:16949557 | Phf3 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Phf3 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of PHF3 mRNA | CTD | PMID:22206623 | Phf3 | Rat | 1,2-dimethylhydrazine | affects expression | ISO | Phf3 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine affects the expression of PHF3 mRNA | CTD | PMID:22206623 | Phf3 | Rat | 2,2',5,5'-tetrachlorobiphenyl | decreases expression | EXP | | 6480464 | 2,5,2',5'-tetrachlorobiphenyl results in decreased expression of PHF3 mRNA | CTD | PMID:23829299 | Phf3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Phf3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PHF3 mRNA | CTD | PMID:19465110 | Phf3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PHF3 mRNA | CTD | PMID:32109520 | Phf3 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of PHF3 mRNA | CTD | PMID:21346803 | Phf3 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Phf3 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of PHF3 mRNA | CTD | PMID:39298647 | Phf3 | Rat | aflatoxin B1 | increases expression | ISO | Phf3 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of PHF3 mRNA | CTD | PMID:19770486 | Phf3 | Rat | aristolochic acid A | decreases expression | ISO | PHF3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of PHF3 mRNA; aristolochic acid I results in more ... | CTD | PMID:33212167 | Phf3 | Rat | arsenite(3-) | multiple interactions | ISO | PHF3 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to PHF3 mRNA] | CTD | PMID:32406909 | Phf3 | Rat | benzo[a]pyrene | decreases methylation | ISO | PHF3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of PHF3 promoter | CTD | PMID:27901495 | Phf3 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | PHF3 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PHF3 mRNA | CTD | PMID:19150397|PMID:26238291 | Phf3 | Rat | beta-lapachone | increases expression | ISO | PHF3 (Homo sapiens) | 6480464 | beta-lapachone results in increased expression of PHF3 mRNA | CTD | PMID:38218311 | Phf3 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Phf3 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of PHF3 mRNA | CTD | PMID:34319233 | Phf3 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Phf3 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of PHF3 mRNA | CTD | PMID:33754040 | Phf3 | Rat | bisphenol A | increases expression | ISO | Phf3 (Mus musculus) | 6480464 | bisphenol A results in increased expression of PHF3 mRNA | CTD | PMID:26063408 | Phf3 | Rat | bisphenol A | multiple interactions | ISO | PHF3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of PHF3 gene | CTD | PMID:31601247 | Phf3 | Rat | bisphenol A | decreases expression | ISO | Phf3 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PHF3 mRNA | CTD | PMID:33221593 | Phf3 | Rat | bisphenol A | increases expression | ISO | PHF3 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of PHF3 mRNA | CTD | PMID:29275510 | Phf3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PHF3 mRNA | CTD | PMID:25181051|PMID:30816183|PMID:32528016 | Phf3 | Rat | cadmium dichloride | decreases expression | ISO | PHF3 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of PHF3 mRNA | CTD | PMID:38568856 | Phf3 | Rat | caffeine | affects phosphorylation | ISO | PHF3 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of PHF3 protein | CTD | PMID:35688186 | Phf3 | Rat | carbon nanotube | decreases expression | ISO | Phf3 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of PHF3 mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681 | Phf3 | Rat | chromium(6+) | multiple interactions | ISO | PHF3 (Homo sapiens) | 6480464 | [zinc chromate results in increased abundance of chromium hexavalent ion] which results in increased expression more ... | CTD | PMID:38479592 | Phf3 | Rat | clobetasol | decreases expression | ISO | Phf3 (Mus musculus) | 6480464 | Clobetasol results in decreased expression of PHF3 mRNA | CTD | PMID:27462272 | Phf3 | Rat | clorgyline | increases expression | ISO | PHF3 (Homo sapiens) | 6480464 | Clorgyline results in increased expression of PHF3 mRNA | CTD | PMID:19691856 | Phf3 | Rat | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of PHF3 mRNA | CTD | PMID:24386269 | Phf3 | Rat | cyclosporin A | affects expression | ISO | Phf3 (Mus musculus) | 6480464 | Cyclosporine affects the expression of PHF3 mRNA | CTD | PMID:19770486 | Phf3 | Rat | DDT | decreases methylation | EXP | | 6480464 | DDT results in decreased methylation of PHF3 gene | CTD | PMID:30207508 | Phf3 | Rat | Dibutyl phosphate | affects expression | ISO | PHF3 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of PHF3 mRNA | CTD | PMID:37042841 | Phf3 | Rat | diuron | decreases expression | ISO | PHF3 (Homo sapiens) | 6480464 | Diuron results in decreased expression of PHF3 mRNA | CTD | PMID:35967413 | Phf3 | Rat | dorsomorphin | multiple interactions | ISO | PHF3 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Phf3 | Rat | doxorubicin | decreases expression | ISO | PHF3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PHF3 mRNA | CTD | PMID:29803840 | Phf3 | Rat | elemental selenium | decreases expression | ISO | PHF3 (Homo sapiens) | 6480464 | Selenium results in decreased expression of PHF3 mRNA | CTD | PMID:19244175 | Phf3 | Rat | enzyme inhibitor | multiple interactions | ISO | PHF3 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Phf3 | Rat | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of PHF3 mRNA | CTD | PMID:24136188 | Phf3 | Rat | FR900359 | affects phosphorylation | ISO | PHF3 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of PHF3 protein | CTD | PMID:37730182 | Phf3 | Rat | fulvestrant | multiple interactions | ISO | PHF3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of PHF3 gene | CTD | PMID:31601247 | Phf3 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of PHF3 mRNA | CTD | PMID:33387578 | Phf3 | Rat | GSK-J4 | increases expression | ISO | PHF3 (Homo sapiens) | 6480464 | GSK-J4 results in increased expression of PHF3 mRNA | CTD | PMID:29301935 | Phf3 | Rat | isoprenaline | increases expression | ISO | Phf3 (Mus musculus) | 6480464 | Isoproterenol results in increased expression of PHF3 mRNA | CTD | PMID:20003209 | Phf3 | Rat | leflunomide | increases expression | ISO | PHF3 (Homo sapiens) | 6480464 | leflunomide results in increased expression of PHF3 mRNA | CTD | PMID:28988120 | Phf3 | Rat | melphalan | decreases expression | ISO | PHF3 (Homo sapiens) | 6480464 | Melphalan results in decreased expression of PHF3 mRNA | CTD | PMID:22363485 | Phf3 | Rat | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of PHF3 gene | CTD | PMID:33148267 | Phf3 | Rat | nicotine | increases expression | ISO | PHF3 (Homo sapiens) | 6480464 | Nicotine results in increased expression of PHF3 mRNA | CTD | PMID:16949557 | Phf3 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | PHF3 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of PHF3 mRNA | CTD | PMID:27153767 | Phf3 | Rat | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of PHF3 gene | CTD | PMID:33148267 | Phf3 | Rat | phenobarbital | affects expression | ISO | PHF3 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of PHF3 mRNA | CTD | PMID:19159669 | Phf3 | Rat | quercetin | increases phosphorylation | ISO | PHF3 (Homo sapiens) | 6480464 | Quercetin results in increased phosphorylation of PHF3 protein | CTD | PMID:35688186 | Phf3 | Rat | resveratrol | multiple interactions | ISO | PHF3 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of PHF3 mRNA | CTD | PMID:23557933 | Phf3 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of PHF3 mRNA | CTD | PMID:19013527 | Phf3 | Rat | SB 431542 | multiple interactions | ISO | PHF3 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Phf3 | Rat | selenium atom | decreases expression | ISO | PHF3 (Homo sapiens) | 6480464 | Selenium results in decreased expression of PHF3 mRNA | CTD | PMID:19244175 | Phf3 | Rat | sodium arsenate | decreases expression | ISO | PHF3 (Homo sapiens) | 6480464 | sodium arsenate results in decreased expression of PHF3 protein | CTD | PMID:38348393 | Phf3 | Rat | sodium fluoride | decreases expression | ISO | Phf3 (Mus musculus) | 6480464 | Sodium Fluoride results in decreased expression of PHF3 mRNA | CTD | PMID:27862939 | Phf3 | Rat | succimer | multiple interactions | ISO | Phf3 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of PHF3 mRNA; [Succimer co-treated more ... | CTD | PMID:21641980|PMID:26378955 | Phf3 | Rat | testosterone enanthate | affects expression | ISO | PHF3 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of PHF3 mRNA | CTD | PMID:17440010 | Phf3 | Rat | titanium dioxide | increases expression | ISO | Phf3 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of PHF3 mRNA | CTD | PMID:23557971 | Phf3 | Rat | trichostatin A | decreases expression | ISO | PHF3 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of PHF3 mRNA | CTD | PMID:26272509 | Phf3 | Rat | trichostatin A | increases expression | ISO | PHF3 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of PHF3 mRNA | CTD | PMID:28542535 | Phf3 | Rat | trichostatin A | multiple interactions | ISO | PHF3 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Phf3 | Rat | troglitazone | decreases expression | ISO | Phf3 (Mus musculus) | 6480464 | troglitazone results in decreased expression of PHF3 mRNA | CTD | PMID:28973697 | Phf3 | Rat | tungsten | decreases expression | ISO | Phf3 (Mus musculus) | 6480464 | Tungsten results in decreased expression of PHF3 mRNA | CTD | PMID:30912803 | Phf3 | Rat | valproic acid | affects expression | ISO | Phf3 (Mus musculus) | 6480464 | Valproic Acid affects the expression of PHF3 mRNA | CTD | PMID:17963808 | Phf3 | Rat | valproic acid | decreases expression | ISO | PHF3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of PHF3 mRNA | CTD | PMID:23179753|PMID:27188386|PMID:28001369 | Phf3 | Rat | vitamin E | decreases expression | ISO | PHF3 (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of PHF3 mRNA | CTD | PMID:19244175 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















