Gene: Myt1 (myelin transcription factor 1) Rattus norvegicus
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Symbol:
Myt1
Name:
myelin transcription factor 1
RGD ID:
1304899
Description:
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including diaphragm development; regulation of gene expression; and regulation of insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human MYT1 (myelin transcription factor 1); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; atrazine.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
LOC362291
RGD Orthologs
Alliance Orthologs
More Info
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More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 189,263,569 - 189,327,844 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 3 189,263,467 - 189,327,844 (+) Ensembl GRCr8 mRatBN7.2 3 168,890,466 - 168,950,341 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 168,886,089 - 168,950,341 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 3 173,296,066 - 173,326,848 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 3 182,255,163 - 182,285,949 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 3 178,920,491 - 178,951,261 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Dahl_SR_JrHsd 3 187,872,422 - 187,933,037 (+) NCBI Dahl_SR_JrHsd Lyon_Normotensive 3 194,731,758 - 194,792,372 (+) NCBI Lyon_Normotensive Lyon_Hypertensive 3 186,701,541 - 186,762,154 (+) NCBI Lyon_Hypertensive F344_StmMcwi 3 167,644,005 - 167,704,619 (+) NCBI F344_StmMcwi Rnor_6.0 3 177,281,365 - 177,341,550 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 177,310,753 - 177,341,547 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 3 180,989,537 - 181,049,955 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 3 170,954,769 - 170,985,583 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 3 163,640,239 - 163,671,029 (-) NCBI Celera RGSC_v3.1 3 170,827,281 - 170,891,617 (+) NCBI Cytogenetic Map 3 q43 NCBI
JBrowse:
Imported Disease Annotations - ClinVar
Only show annotations with direct experimental evidence (0 objects hidden)
Myt1 Rat (S)-colchicine increases phosphorylation ISO MYT1 (Homo sapiens) 6480464 Colchicine results in increased phosphorylation of MYT1 protein CTD PMID:16611024 Myt1 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Myt1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Myt1 Rat 17beta-estradiol increases expression ISO MYT1 (Homo sapiens) 6480464 Estradiol results in increased expression of MYT1 mRNA CTD PMID:17268063 Myt1 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Myt1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Myt1 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Myt1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Myt1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Myt1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of MYT1 mRNA CTD PMID:24058054 Myt1 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Myt1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Myt1 Rat 2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one increases expression ISO Myt1 (Mus musculus) 6480464 Itraconazole results in increased expression of MYT1 mRNA CTD PMID:31099283 Myt1 Rat 2-methylcholine affects expression ISO MYT1 (Homo sapiens) 6480464 beta-methylcholine affects the expression of MYT1 mRNA CTD PMID:21179406 Myt1 Rat 4,4'-sulfonyldiphenol decreases expression ISO Myt1 (Mus musculus) 6480464 bisphenol S results in decreased expression of MYT1 mRNA CTD PMID:30951980 Myt1 Rat 4,4'-sulfonyldiphenol affects methylation ISO Myt1 (Mus musculus) 6480464 bisphenol S affects the methylation of MYT1 gene CTD PMID:31683443 Myt1 Rat 4,4'-sulfonyldiphenol increases methylation ISO Myt1 (Mus musculus) 6480464 bisphenol S results in increased methylation of MYT1 exon CTD PMID:33297965 Myt1 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of MYT1 mRNA CTD PMID:24780913 Myt1 Rat acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of MYT1 mRNA CTD PMID:28959563 Myt1 Rat aflatoxin B1 increases methylation ISO MYT1 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of MYT1 gene CTD PMID:27153756 Myt1 Rat aflatoxin B1 decreases methylation ISO MYT1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of MYT1 intron CTD PMID:30157460 Myt1 Rat Aflatoxin B2 alpha increases methylation ISO MYT1 (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of MYT1 intron CTD PMID:30157460 Myt1 Rat all-trans-retinoic acid increases expression ISO Myt1 (Mus musculus) 6480464 Tretinoin results in increased expression of MYT1 mRNA CTD PMID:16169686 Myt1 Rat aristolochic acid A decreases expression ISO MYT1 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of MYT1 mRNA CTD PMID:33212167 Myt1 Rat arsenite(3-) increases methylation ISO MYT1 (Homo sapiens) 6480464 arsenite results in increased methylation of MYT1 promoter CTD PMID:23974009 Myt1 Rat atrazine affects methylation EXP 6480464 Atrazine affects the methylation of MYT1 gene CTD PMID:35440735 Myt1 Rat benzo[a]pyrene decreases expression ISO MYT1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of MYT1 mRNA CTD PMID:16120219 Myt1 Rat benzo[a]pyrene affects methylation ISO MYT1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of MYT1 5' UTR; Benzo(a)pyrene affects the methylation of MYT1 exon; more ... CTD PMID:27901495|PMID:30157460 Myt1 Rat benzo[e]pyrene increases methylation ISO MYT1 (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of MYT1 intron CTD PMID:30157460 Myt1 Rat bisphenol A increases expression ISO MYT1 (Homo sapiens) 6480464 bisphenol A results in increased expression of MYT1 mRNA CTD PMID:17268063 Myt1 Rat bisphenol A decreases expression ISO Myt1 (Mus musculus) 6480464 bisphenol A results in decreased expression of MYT1 mRNA CTD PMID:32156529 Myt1 Rat bisphenol A affects methylation ISO Myt1 (Mus musculus) 6480464 bisphenol A affects the methylation of MYT1 promoter CTD PMID:27334623 Myt1 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of MYT1 mRNA CTD PMID:25181051 Myt1 Rat butanal increases expression ISO MYT1 (Homo sapiens) 6480464 butyraldehyde results in increased expression of MYT1 mRNA CTD PMID:26079696 Myt1 Rat butanal increases methylation ISO MYT1 (Homo sapiens) 6480464 butyraldehyde results in increased methylation of MYT1 gene CTD PMID:30002397 Myt1 Rat CGP 52608 multiple interactions ISO MYT1 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to MYT1 gene] CTD PMID:28238834 Myt1 Rat copper atom multiple interactions EXP 6480464 [Copper co-treated with Dietary Sucrose] results in increased expression of MYT1 mRNA CTD PMID:26033743 Myt1 Rat copper atom increases expression EXP 6480464 Copper deficiency results in increased expression of MYT1 mRNA CTD PMID:26033743 Myt1 Rat copper(0) multiple interactions EXP 6480464 [Copper co-treated with Dietary Sucrose] results in increased expression of MYT1 mRNA CTD PMID:26033743 Myt1 Rat copper(0) increases expression EXP 6480464 Copper deficiency results in increased expression of MYT1 mRNA CTD PMID:26033743 Myt1 Rat cryptolepine decreases expression ISO MYT1 (Homo sapiens) 6480464 cryptolepine results in decreased expression of MYT1 mRNA CTD PMID:16120219 Myt1 Rat Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of MYT1 mRNA CTD PMID:26577399 Myt1 Rat dorsomorphin multiple interactions ISO MYT1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Myt1 Rat doxorubicin increases phosphorylation ISO Myt1 (Mus musculus) 6480464 Doxorubicin results in increased phosphorylation of MYT1 protein CTD PMID:15861398 Myt1 Rat etoposide decreases expression ISO MYT1 (Homo sapiens) 6480464 Etoposide results in decreased expression of MYT1 mRNA CTD PMID:16120219 Myt1 Rat folic acid decreases expression ISO Myt1 (Mus musculus) 6480464 Folic Acid results in decreased expression of MYT1 mRNA CTD PMID:25629700 Myt1 Rat heptanal increases methylation ISO MYT1 (Homo sapiens) 6480464 heptanal results in increased methylation of MYT1 gene CTD PMID:30002397 Myt1 Rat hexanal increases methylation ISO MYT1 (Homo sapiens) 6480464 n-hexanal results in increased methylation of MYT1 gene CTD PMID:30002397 Myt1 Rat itraconazole increases expression ISO Myt1 (Mus musculus) 6480464 Itraconazole results in increased expression of MYT1 mRNA CTD PMID:31099283 Myt1 Rat ketoconazole increases expression ISO Myt1 (Mus musculus) 6480464 Ketoconazole results in increased expression of MYT1 mRNA CTD PMID:31099283 Myt1 Rat lead(0) decreases expression ISO MYT1 (Homo sapiens) 6480464 Lead results in decreased expression of MYT1 mRNA CTD PMID:19921347 Myt1 Rat lead(0) affects expression ISO MYT1 (Homo sapiens) 6480464 Lead affects the expression of MYT1 mRNA CTD PMID:28903495 Myt1 Rat methamphetamine decreases expression EXP 6480464 Methamphetamine results in decreased expression of MYT1 mRNA CTD PMID:19564919 Myt1 Rat methapyrilene increases methylation ISO MYT1 (Homo sapiens) 6480464 Methapyrilene results in increased methylation of MYT1 intron CTD PMID:30157460 Myt1 Rat N-ethyl-N-nitrosourea decreases expression ISO Myt1 (Mus musculus) 6480464 Ethylnitrosourea results in decreased expression of MYT1 protein CTD PMID:28549617 Myt1 Rat naphthalene increases expression ISO Myt1 (Mus musculus) 6480464 naphthalene results in increased expression of MYT1 mRNA CTD PMID:18978301 Myt1 Rat nocodazole increases phosphorylation ISO MYT1 (Homo sapiens) 6480464 Nocodazole results in increased phosphorylation of MYT1 protein CTD PMID:16611024 Myt1 Rat nonanal increases methylation ISO MYT1 (Homo sapiens) 6480464 nonanal results in increased methylation of MYT1 gene CTD PMID:30002397 Myt1 Rat octanal increases methylation ISO MYT1 (Homo sapiens) 6480464 caprylic aldehyde results in increased methylation of MYT1 gene CTD PMID:30002397 Myt1 Rat ozone multiple interactions ISO Myt1 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of MYT1 more ... CTD PMID:27106289 Myt1 Rat PCB138 multiple interactions ISO Myt1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Myt1 Rat pentanal increases expression ISO MYT1 (Homo sapiens) 6480464 pentanal results in increased expression of MYT1 mRNA CTD PMID:26079696 Myt1 Rat pentanal increases methylation ISO MYT1 (Homo sapiens) 6480464 pentanal results in increased methylation of MYT1 gene CTD PMID:30002397 Myt1 Rat permethrin increases expression ISO MYT1 (Homo sapiens) 6480464 Permethrin results in increased expression of MYT1 mRNA CTD PMID:37047231 Myt1 Rat phenylmercury acetate decreases expression ISO MYT1 (Homo sapiens) 6480464 Phenylmercuric Acetate results in decreased expression of MYT1 mRNA CTD PMID:26272509 Myt1 Rat phenylmercury acetate multiple interactions ISO MYT1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Myt1 Rat propanal increases expression ISO MYT1 (Homo sapiens) 6480464 propionaldehyde results in increased expression of MYT1 mRNA CTD PMID:26079696 Myt1 Rat propanal increases methylation ISO MYT1 (Homo sapiens) 6480464 propionaldehyde results in increased methylation of MYT1 gene CTD PMID:30002397 Myt1 Rat SB 431542 multiple interactions ISO MYT1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Myt1 Rat sodium arsenite decreases expression ISO MYT1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of MYT1 mRNA CTD PMID:29301061|PMID:32844245 Myt1 Rat sodium arsenite decreases expression ISO Myt1 (Mus musculus) 6480464 sodium arsenite results in decreased expression of MYT1 mRNA CTD PMID:36209798 Myt1 Rat sodium arsenite increases methylation ISO MYT1 (Homo sapiens) 6480464 sodium arsenite results in increased methylation of MYT1 intron CTD PMID:32844245 Myt1 Rat Soman decreases expression EXP 6480464 Soman results in decreased expression of MYT1 mRNA CTD PMID:19281266 Myt1 Rat triptonide increases expression ISO Myt1 (Mus musculus) 6480464 triptonide results in increased expression of MYT1 mRNA CTD PMID:33045310 Myt1 Rat valproic acid increases methylation ISO MYT1 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of MYT1 gene CTD PMID:29154799 Myt1 Rat valproic acid affects expression ISO MYT1 (Homo sapiens) 6480464 Valproic Acid affects the expression of MYT1 mRNA CTD PMID:25979313 Myt1 Rat vorinostat decreases expression ISO MYT1 (Homo sapiens) 6480464 vorinostat results in decreased expression of MYT1 mRNA CTD PMID:27188386