Gene: Myt1 (myelin transcription factor 1) Rattus norvegicus
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Symbol:
Myt1
Name:
myelin transcription factor 1
RGD ID:
1304899
Description:
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including diaphragm development; regulation of gene expression; and regulation of insulin secretion involved in cellular response to glucose stimulus. Predicted to be active in nucleus. Orthologous to human MYT1 (myelin transcription factor 1); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; atrazine.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
LOC362291
RGD Orthologs
Alliance Orthologs
More Info
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Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 189,263,569 - 189,327,844 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 3 189,263,467 - 189,327,844 (+) Ensembl GRCr8 mRatBN7.2 3 168,890,466 - 168,950,341 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 168,886,089 - 168,950,341 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 3 173,296,066 - 173,326,848 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 3 182,255,163 - 182,285,949 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 3 178,920,491 - 178,951,261 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 3 177,281,365 - 177,341,550 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 177,310,753 - 177,341,547 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 3 180,989,537 - 181,049,955 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 3 170,954,769 - 170,985,583 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 3 163,640,239 - 163,671,029 (-) NCBI Celera RGSC_v3.1 3 170,827,281 - 170,891,617 (+) NCBI Cytogenetic Map 3 q43 NCBI
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Imported Disease Annotations - ClinVar
Only show annotations with direct experimental evidence (0 objects hidden)
Myt1 Rat (S)-colchicine increases phosphorylation ISO MYT1 (Homo sapiens) 6480464 Colchicine results in increased phosphorylation of MYT1 protein CTD PMID:16611024 Myt1 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Myt1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Myt1 Rat 17beta-estradiol increases expression ISO MYT1 (Homo sapiens) 6480464 Estradiol results in increased expression of MYT1 mRNA CTD PMID:17268063 Myt1 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Myt1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Myt1 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Myt1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Myt1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Myt1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of MYT1 mRNA CTD PMID:24058054 Myt1 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Myt1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Myt1 Rat 2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one increases expression ISO Myt1 (Mus musculus) 6480464 Itraconazole results in increased expression of MYT1 mRNA CTD PMID:31099283 Myt1 Rat 2-methylcholine affects expression ISO MYT1 (Homo sapiens) 6480464 beta-methylcholine affects the expression of MYT1 mRNA CTD PMID:21179406 Myt1 Rat 4,4'-sulfonyldiphenol decreases expression ISO Myt1 (Mus musculus) 6480464 bisphenol S results in decreased expression of MYT1 mRNA CTD PMID:30951980 Myt1 Rat 4,4'-sulfonyldiphenol affects methylation ISO Myt1 (Mus musculus) 6480464 bisphenol S affects the methylation of MYT1 gene CTD PMID:31683443 Myt1 Rat 4,4'-sulfonyldiphenol increases methylation ISO Myt1 (Mus musculus) 6480464 bisphenol S results in increased methylation of MYT1 exon CTD PMID:33297965 Myt1 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of MYT1 mRNA CTD PMID:24780913 Myt1 Rat acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of MYT1 mRNA CTD PMID:28959563 Myt1 Rat aflatoxin B1 increases methylation ISO MYT1 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of MYT1 gene CTD PMID:27153756 Myt1 Rat aflatoxin B1 decreases methylation ISO MYT1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of MYT1 intron CTD PMID:30157460 Myt1 Rat Aflatoxin B2 alpha increases methylation ISO MYT1 (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of MYT1 intron CTD PMID:30157460 Myt1 Rat all-trans-retinoic acid increases expression ISO Myt1 (Mus musculus) 6480464 Tretinoin results in increased expression of MYT1 mRNA CTD PMID:16169686 Myt1 Rat aristolochic acid A decreases expression ISO MYT1 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of MYT1 mRNA CTD PMID:33212167 Myt1 Rat arsenite(3-) increases methylation ISO MYT1 (Homo sapiens) 6480464 arsenite results in increased methylation of MYT1 promoter CTD PMID:23974009 Myt1 Rat atrazine affects methylation EXP 6480464 Atrazine affects the methylation of MYT1 gene CTD PMID:35440735 Myt1 Rat benzo[a]pyrene decreases expression ISO MYT1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of MYT1 mRNA CTD PMID:16120219 Myt1 Rat benzo[a]pyrene affects methylation ISO MYT1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of MYT1 5' UTR; Benzo(a)pyrene affects the methylation of MYT1 exon; more ... CTD PMID:27901495|PMID:30157460 Myt1 Rat benzo[e]pyrene increases methylation ISO MYT1 (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of MYT1 intron CTD PMID:30157460 Myt1 Rat bisphenol A increases expression ISO MYT1 (Homo sapiens) 6480464 bisphenol A results in increased expression of MYT1 mRNA CTD PMID:17268063 Myt1 Rat bisphenol A decreases expression ISO Myt1 (Mus musculus) 6480464 bisphenol A results in decreased expression of MYT1 mRNA CTD PMID:32156529 Myt1 Rat bisphenol A affects methylation ISO Myt1 (Mus musculus) 6480464 bisphenol A affects the methylation of MYT1 promoter CTD PMID:27334623 Myt1 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of MYT1 mRNA CTD PMID:25181051 Myt1 Rat butanal increases expression ISO MYT1 (Homo sapiens) 6480464 butyraldehyde results in increased expression of MYT1 mRNA CTD PMID:26079696 Myt1 Rat butanal increases methylation ISO MYT1 (Homo sapiens) 6480464 butyraldehyde results in increased methylation of MYT1 gene CTD PMID:30002397 Myt1 Rat CGP 52608 multiple interactions ISO MYT1 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to MYT1 gene] CTD PMID:28238834 Myt1 Rat copper atom multiple interactions EXP 6480464 [Copper co-treated with Dietary Sucrose] results in increased expression of MYT1 mRNA CTD PMID:26033743 Myt1 Rat copper atom increases expression EXP 6480464 Copper deficiency results in increased expression of MYT1 mRNA CTD PMID:26033743 Myt1 Rat copper(0) multiple interactions EXP 6480464 [Copper co-treated with Dietary Sucrose] results in increased expression of MYT1 mRNA CTD PMID:26033743 Myt1 Rat copper(0) increases expression EXP 6480464 Copper deficiency results in increased expression of MYT1 mRNA CTD PMID:26033743 Myt1 Rat cryptolepine decreases expression ISO MYT1 (Homo sapiens) 6480464 cryptolepine results in decreased expression of MYT1 mRNA CTD PMID:16120219 Myt1 Rat Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of MYT1 mRNA CTD PMID:26577399 Myt1 Rat dorsomorphin multiple interactions ISO MYT1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Myt1 Rat doxorubicin increases phosphorylation ISO Myt1 (Mus musculus) 6480464 Doxorubicin results in increased phosphorylation of MYT1 protein CTD PMID:15861398 Myt1 Rat etoposide decreases expression ISO MYT1 (Homo sapiens) 6480464 Etoposide results in decreased expression of MYT1 mRNA CTD PMID:16120219 Myt1 Rat folic acid decreases expression ISO Myt1 (Mus musculus) 6480464 Folic Acid results in decreased expression of MYT1 mRNA CTD PMID:25629700 Myt1 Rat heptanal increases methylation ISO MYT1 (Homo sapiens) 6480464 heptanal results in increased methylation of MYT1 gene CTD PMID:30002397 Myt1 Rat hexanal increases methylation ISO MYT1 (Homo sapiens) 6480464 n-hexanal results in increased methylation of MYT1 gene CTD PMID:30002397 Myt1 Rat itraconazole increases expression ISO Myt1 (Mus musculus) 6480464 Itraconazole results in increased expression of MYT1 mRNA CTD PMID:31099283 Myt1 Rat ketoconazole increases expression ISO Myt1 (Mus musculus) 6480464 Ketoconazole results in increased expression of MYT1 mRNA CTD PMID:31099283 Myt1 Rat lead(0) decreases expression ISO MYT1 (Homo sapiens) 6480464 Lead results in decreased expression of MYT1 mRNA CTD PMID:19921347 Myt1 Rat lead(0) affects expression ISO MYT1 (Homo sapiens) 6480464 Lead affects the expression of MYT1 mRNA CTD PMID:28903495 Myt1 Rat methamphetamine decreases expression EXP 6480464 Methamphetamine results in decreased expression of MYT1 mRNA CTD PMID:19564919 Myt1 Rat methapyrilene increases methylation ISO MYT1 (Homo sapiens) 6480464 Methapyrilene results in increased methylation of MYT1 intron CTD PMID:30157460 Myt1 Rat N-ethyl-N-nitrosourea decreases expression ISO Myt1 (Mus musculus) 6480464 Ethylnitrosourea results in decreased expression of MYT1 protein CTD PMID:28549617 Myt1 Rat naphthalene increases expression ISO Myt1 (Mus musculus) 6480464 naphthalene results in increased expression of MYT1 mRNA CTD PMID:18978301 Myt1 Rat nocodazole increases phosphorylation ISO MYT1 (Homo sapiens) 6480464 Nocodazole results in increased phosphorylation of MYT1 protein CTD PMID:16611024 Myt1 Rat nonanal increases methylation ISO MYT1 (Homo sapiens) 6480464 nonanal results in increased methylation of MYT1 gene CTD PMID:30002397 Myt1 Rat octanal increases methylation ISO MYT1 (Homo sapiens) 6480464 caprylic aldehyde results in increased methylation of MYT1 gene CTD PMID:30002397 Myt1 Rat ozone multiple interactions ISO Myt1 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of MYT1 more ... CTD PMID:27106289 Myt1 Rat PCB138 multiple interactions ISO Myt1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Myt1 Rat pentanal increases expression ISO MYT1 (Homo sapiens) 6480464 pentanal results in increased expression of MYT1 mRNA CTD PMID:26079696 Myt1 Rat pentanal increases methylation ISO MYT1 (Homo sapiens) 6480464 pentanal results in increased methylation of MYT1 gene CTD PMID:30002397 Myt1 Rat permethrin increases expression ISO MYT1 (Homo sapiens) 6480464 Permethrin results in increased expression of MYT1 mRNA CTD PMID:37047231 Myt1 Rat phenylmercury acetate decreases expression ISO MYT1 (Homo sapiens) 6480464 Phenylmercuric Acetate results in decreased expression of MYT1 mRNA CTD PMID:26272509 Myt1 Rat phenylmercury acetate multiple interactions ISO MYT1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Myt1 Rat propanal increases expression ISO MYT1 (Homo sapiens) 6480464 propionaldehyde results in increased expression of MYT1 mRNA CTD PMID:26079696 Myt1 Rat propanal increases methylation ISO MYT1 (Homo sapiens) 6480464 propionaldehyde results in increased methylation of MYT1 gene CTD PMID:30002397 Myt1 Rat SB 431542 multiple interactions ISO MYT1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Myt1 Rat sodium arsenite decreases expression ISO MYT1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of MYT1 mRNA CTD PMID:29301061|PMID:32844245 Myt1 Rat sodium arsenite decreases expression ISO Myt1 (Mus musculus) 6480464 sodium arsenite results in decreased expression of MYT1 mRNA CTD PMID:36209798 Myt1 Rat sodium arsenite increases methylation ISO MYT1 (Homo sapiens) 6480464 sodium arsenite results in increased methylation of MYT1 intron CTD PMID:32844245 Myt1 Rat Soman decreases expression EXP 6480464 Soman results in decreased expression of MYT1 mRNA CTD PMID:19281266 Myt1 Rat triptonide increases expression ISO Myt1 (Mus musculus) 6480464 triptonide results in increased expression of MYT1 mRNA CTD PMID:33045310 Myt1 Rat valproic acid increases methylation ISO MYT1 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of MYT1 gene CTD PMID:29154799 Myt1 Rat valproic acid affects expression ISO MYT1 (Homo sapiens) 6480464 Valproic Acid affects the expression of MYT1 mRNA CTD PMID:25979313 Myt1 Rat vorinostat decreases expression ISO MYT1 (Homo sapiens) 6480464 vorinostat results in decreased expression of MYT1 mRNA CTD PMID:27188386