Trpm3 (transient receptor potential cation channel, subfamily M, member 3) - Rat Genome Database

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Gene: Trpm3 (transient receptor potential cation channel, subfamily M, member 3) Rattus norvegicus
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Symbol: Trpm3
Name: transient receptor potential cation channel, subfamily M, member 3
RGD ID: 1304888
Description: Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to act upstream of or within monoatomic cation transport. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in cataract. Orthologous to human TRPM3 (transient receptor potential cation channel subfamily M member 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aflatoxin B1.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC309407; transient receptor potential cation channel subfamily M member 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81229,099,741 - 229,984,172 (+)NCBIGRCr8
mRatBN7.21219,673,200 - 220,557,610 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1219,672,892 - 220,560,717 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1228,126,334 - 228,996,882 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01235,056,436 - 235,926,937 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01227,874,450 - 228,744,986 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01239,741,572 - 240,757,583 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1240,355,149 - 240,757,583 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01247,027,120 - 247,810,732 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01247,942,661 - 248,041,913 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41225,377,097 - 226,276,992 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11225,865,833 - 226,439,441 (+)NCBI
Celera1216,900,275 - 217,774,744 (+)NCBICelera
Cytogenetic Map1q51NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
plasma membrane  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15824111   PMID:17712480   PMID:18978782   PMID:20163522   PMID:21257751   PMID:21948387   PMID:21955047   PMID:33030499   PMID:33166100   PMID:33296617   PMID:33518671   PMID:34884938  
PMID:35413036   PMID:37146443  


Genomics

Comparative Map Data
Trpm3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81229,099,741 - 229,984,172 (+)NCBIGRCr8
mRatBN7.21219,673,200 - 220,557,610 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1219,672,892 - 220,560,717 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1228,126,334 - 228,996,882 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01235,056,436 - 235,926,937 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01227,874,450 - 228,744,986 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01239,741,572 - 240,757,583 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1240,355,149 - 240,757,583 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01247,027,120 - 247,810,732 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01247,942,661 - 248,041,913 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41225,377,097 - 226,276,992 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11225,865,833 - 226,439,441 (+)NCBI
Celera1216,900,275 - 217,774,744 (+)NCBICelera
Cytogenetic Map1q51NCBI
TRPM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38970,529,060 - 71,446,971 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl970,529,060 - 71,446,977 (-)EnsemblGRCh38hg38GRCh38
GRCh37973,143,976 - 74,061,887 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36972,339,769 - 72,926,334 (-)NCBINCBI36Build 36hg18NCBI36
Celera943,740,296 - 44,308,807 (-)NCBICelera
Cytogenetic Map9q21.12-q21.13NCBI
HuRef942,990,124 - 43,559,409 (-)NCBIHuRef
CHM1_1973,296,608 - 73,882,917 (-)NCBICHM1_1
T2T-CHM13v2.0982,695,847 - 83,597,417 (-)NCBIT2T-CHM13v2.0
Trpm3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391922,114,789 - 22,972,774 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1922,116,410 - 22,972,774 (+)EnsemblGRCm39 Ensembl
GRCm381922,137,797 - 22,995,410 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1922,139,046 - 22,995,410 (+)EnsemblGRCm38mm10GRCm38
MGSCv371922,213,607 - 23,064,374 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361922,206,214 - 23,056,981 (+)NCBIMGSCv36mm8
Celera1922,863,961 - 23,712,483 (+)NCBICelera
Cytogenetic Map19BNCBI
cM Map1916.05NCBI
Trpm3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554341,725,692 - 2,542,077 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554342,017,809 - 2,543,827 (+)NCBIChiLan1.0ChiLan1.0
TRPM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21169,729,091 - 70,634,552 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1969,735,031 - 70,640,633 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0953,367,505 - 54,272,917 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1969,286,220 - 70,189,177 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl969,292,593 - 69,606,949 (-)Ensemblpanpan1.1panPan2
TRPM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1186,525,054 - 87,023,561 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl186,242,487 - 87,017,292 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha186,997,042 - 87,495,355 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0186,977,918 - 87,572,008 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl186,695,268 - 87,570,615 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1186,738,803 - 87,230,190 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0186,444,184 - 86,935,800 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0187,201,388 - 87,693,419 (+)NCBIUU_Cfam_GSD_1.0
Trpm3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947133,674,904 - 134,486,513 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365036,690,043 - 7,497,963 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365036,688,476 - 7,188,417 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRPM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1223,836,213 - 224,680,389 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11223,833,263 - 224,682,424 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21250,297,464 - 250,831,887 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRPM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11281,608,301 - 82,616,349 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1281,609,229 - 81,925,984 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603870,019,264 - 70,927,870 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trpm3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247361,660,831 - 2,514,430 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247361,972,654 - 2,516,053 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Trpm3
5589 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:651
Count of miRNA genes:292
Interacting mature miRNAs:372
Transcripts:ENSRNOT00000018521
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8693637Alc29Alcohol consumption QTL 292.70.258drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1207987464234238494Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
5508828Leukc3Leukocyte quantity QTL 3eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)1218108584224054420Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
61455Niddm7Non-insulin dependent diabetes mellitus QTL 75.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1214537555238757011Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1206081677251081677Rat
1558658Bw59Body weight QTL 593.50.0003body mass (VT:0001259)body weight (CMO:0000012)1178784622223784622Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1184550676229550676Rat
8693661Alc34Alcohol consumption QTL 342.20.611drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1207987464228627600Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1201554356246554356Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1123556856242907031Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1185145134221264292Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1183970203243914901Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1191019702246062233Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1201554356246554356Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1213707201252085212Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1181133855226133855Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1201554356246554356Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1197814409242814409Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1193113876238113876Rat
734768Niddm59Non-insulin dependent diabetes mellitus QTL 59body mass (VT:0001259)body weight (CMO:0000012)1213843987258843987Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1218753816256448513Rat
1358890Bp259Blood pressure QTL 2593.06arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1210702053260522016Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
1358292Cm37Cardiac mass QTL 376.28e-07heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1196248093241248093Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1197814409242814409Rat
634312Bp143Blood pressure QTL 14330.0002arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1182623426219932796Rat
1549910Bw54Body weight QTL 540.05body mass (VT:0001259)body weight (CMO:0000012)1214647894259647894Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1214647894259647894Rat
1357399Bw45Body weight QTL 453.05body mass (VT:0001259)body mass index (BMI) (CMO:0000105)1206329708251329708Rat
1357404Bw42Body weight QTL 424.490.0001body mass (VT:0001259)body weight (CMO:0000012)1206329708251329708Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1176869060221869060Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1210702053240947965Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1185356336231689108Rat
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1199368955224569684Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1178810256240830002Rat
61400Niddm1Non-insulin dependent diabetes mellitus QTL 111blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1218753689245907899Rat
2292216Bw80Body weight QTL 803.230.0019body mass (VT:0001259)body weight (CMO:0000012)1213533809243914901Rat
1331790Bp201Blood pressure QTL 2013.127arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1198211513225126682Rat
10059587Bw173Body weight QTL 1733.230.025body mass (VT:0001259)body weight (CMO:0000012)1202069611247069611Rat
1300168Bp170Blood pressure QTL 1702.76arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1207702246228581766Rat
61403Niddm4Non-insulin dependent diabetes mellitus QTL 4blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1206329708222745518Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1197697768238755659Rat
10059590Kidm44Kidney mass QTL 443.420.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1191033875236033875Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1196248093241248093Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1176550523221550523Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1188377360224054420Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1183970203243914901Rat
634340Hcar5Hepatocarcinoma resistance QTL 58liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1214537555226660468Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1197670404242670404Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1203995416244113296Rat
8693618Alc25Alcohol consumption QTL 2530.28drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1207987464228627600Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1181829673224569684Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1216255568260522016Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
1358191Ept10Estrogen-induced pituitary tumorigenesis QTL 103.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)1192825253243914732Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1218748008257976495Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1201554356246554356Rat

Markers in Region
D1Rat298  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21219,932,573 - 219,932,796 (+)MAPPERmRatBN7.2
Rnor_6.01240,017,117 - 240,017,341NCBIRnor6.0
Rnor_5.01247,303,036 - 247,303,260UniSTSRnor5.0
RGSC_v3.41225,625,031 - 225,625,256RGDRGSC3.4
RGSC_v3.41225,625,032 - 225,625,256UniSTSRGSC3.4
RGSC_v3.11225,789,054 - 225,789,279RGD
Celera1217,158,892 - 217,159,116UniSTS
SHRSP x BN Map1116.5799RGD
SHRSP x BN Map1116.5799UniSTS
Cytogenetic Map1q51UniSTS
D1Rat370  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21220,165,574 - 220,165,798 (+)MAPPERmRatBN7.2
Rnor_6.01240,251,616 - 240,251,839NCBIRnor6.0
Rnor_5.01247,538,736 - 247,538,959UniSTSRnor5.0
RGSC_v3.41225,860,708 - 225,860,932RGDRGSC3.4
RGSC_v3.41225,860,709 - 225,860,932UniSTSRGSC3.4
RGSC_v3.11226,024,731 - 226,024,955RGD
Celera1217,385,744 - 217,385,967UniSTS
SHRSP x BN Map1116.5799RGD
SHRSP x BN Map1116.5799UniSTS
Cytogenetic Map1q51UniSTS
D1Rat369  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21220,461,115 - 220,461,370 (+)MAPPERmRatBN7.2
Rnor_6.01240,660,288 - 240,660,546NCBIRnor6.0
Rnor_5.01247,946,430 - 247,946,688UniSTSRnor5.0
RGSC_v3.41226,179,791 - 226,180,047RGDRGSC3.4
RGSC_v3.41226,179,792 - 226,180,048UniSTSRGSC3.4
RGSC_v3.11226,343,814 - 226,344,070RGD
Celera1217,677,579 - 217,677,821UniSTS
SHRSP x BN Map1116.5799RGD
SHRSP x BN Map1116.5799UniSTS
Cytogenetic Map1q51UniSTS
D19Ertd744e  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21220,551,196 - 220,551,416 (+)MAPPERmRatBN7.2
Rnor_6.01240,751,174 - 240,751,393NCBIRnor6.0
Rnor_5.01248,035,504 - 248,035,723UniSTSRnor5.0
RGSC_v3.41226,270,583 - 226,270,802UniSTSRGSC3.4
Celera1217,768,335 - 217,768,554UniSTS
Cytogenetic Map1q51UniSTS
RH144107  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21220,556,140 - 220,556,311 (+)MAPPERmRatBN7.2
Rnor_6.01240,756,114 - 240,756,284NCBIRnor6.0
Rnor_5.01248,040,444 - 248,040,614UniSTSRnor5.0
RGSC_v3.41226,275,523 - 226,275,693UniSTSRGSC3.4
Celera1217,773,275 - 217,773,445UniSTS
RH 3.4 Map11615.31UniSTS
Cytogenetic Map1q51UniSTS
BE102851  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21220,488,174 - 220,488,366 (+)MAPPERmRatBN7.2
Rnor_6.01240,687,347 - 240,687,538NCBIRnor6.0
Rnor_5.01247,973,370 - 247,973,561UniSTSRnor5.0
RGSC_v3.41226,206,867 - 226,207,058UniSTSRGSC3.4
Celera1217,704,852 - 217,705,043UniSTS
RH 3.4 Map11614.3UniSTS
Cytogenetic Map1q51UniSTS
BE107788  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21220,127,904 - 220,128,108 (+)MAPPERmRatBN7.2
Rnor_6.01240,214,177 - 240,214,380NCBIRnor6.0
Rnor_5.01247,501,219 - 247,501,422UniSTSRnor5.0
RGSC_v3.41225,820,965 - 225,821,168UniSTSRGSC3.4
Celera1217,347,814 - 217,348,017UniSTS
RH 3.4 Map11615.2UniSTS
Cytogenetic Map1q51UniSTS
BE108061  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21220,051,657 - 220,051,840 (+)MAPPERmRatBN7.2
Rnor_6.01240,133,150 - 240,133,332NCBIRnor6.0
Rnor_5.01247,420,108 - 247,420,290UniSTSRnor5.0
RGSC_v3.41225,745,103 - 225,745,285UniSTSRGSC3.4
Celera1217,271,340 - 217,271,522UniSTS
RH 3.4 Map11617.5UniSTS
Cytogenetic Map1q51UniSTS
BF405786  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21220,121,237 - 220,121,422 (+)MAPPERmRatBN7.2
Rnor_6.01240,207,089 - 240,207,273NCBIRnor6.0
Rnor_5.01247,494,047 - 247,494,231UniSTSRnor5.0
RGSC_v3.41225,814,121 - 225,814,305UniSTSRGSC3.4
Celera1217,341,142 - 217,341,326UniSTS
RH 3.4 Map11614.9UniSTS
Cytogenetic Map1q51UniSTS
RH135031  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21220,337,603 - 220,337,784 (+)MAPPERmRatBN7.2
Rnor_6.01240,423,678 - 240,423,858NCBIRnor6.0
Rnor_5.01247,710,868 - 247,711,048UniSTSRnor5.0
RGSC_v3.41226,033,672 - 226,033,852UniSTSRGSC3.4
Celera1217,555,078 - 217,555,258UniSTS
RH 3.4 Map11615.51UniSTS
Cytogenetic Map1q51UniSTS
RH135304  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21219,811,320 - 219,811,525 (+)MAPPERmRatBN7.2
Rnor_6.01239,881,284 - 239,881,488NCBIRnor6.0
Rnor_5.01247,166,315 - 247,166,519UniSTSRnor5.0
RGSC_v3.41225,503,160 - 225,503,364UniSTSRGSC3.4
Celera1217,037,876 - 217,038,100UniSTS
Cytogenetic Map1q51UniSTS
BF415773  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21220,144,561 - 220,144,692 (+)MAPPERmRatBN7.2
Rnor_6.01240,230,832 - 240,230,962NCBIRnor6.0
Rnor_5.01247,517,874 - 247,518,004UniSTSRnor5.0
RGSC_v3.41225,837,620 - 225,837,750UniSTSRGSC3.4
Celera1217,364,469 - 217,364,599UniSTS
RH 3.4 Map11617.32UniSTS
Cytogenetic Map1q51UniSTS
BF416487  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21220,472,338 - 220,472,485 (+)MAPPERmRatBN7.2
Rnor_6.01240,671,511 - 240,671,657NCBIRnor6.0
Rnor_5.01247,957,534 - 247,957,680UniSTSRnor5.0
RGSC_v3.41226,191,031 - 226,191,177UniSTSRGSC3.4
Celera1217,689,016 - 217,689,162UniSTS
RH 3.4 Map11615.92UniSTS
Cytogenetic Map1q51UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 41 113 60 59 28 25 28 6 179 89 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000018521   ⟹   ENSRNOP00000018521
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1220,008,655 - 220,557,610 (+)Ensembl
Rnor_6.0 Ensembl1240,355,149 - 240,757,583 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098066   ⟹   ENSRNOP00000081604
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1220,008,970 - 220,342,837 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109194   ⟹   ENSRNOP00000084148
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1219,672,892 - 220,557,610 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113385   ⟹   ENSRNOP00000083902
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1219,672,892 - 220,557,610 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114759   ⟹   ENSRNOP00000084016
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1220,008,655 - 220,560,717 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114800   ⟹   ENSRNOP00000093587
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1220,008,655 - 220,557,610 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115994   ⟹   ENSRNOP00000094201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1220,008,970 - 220,341,856 (+)Ensembl
RefSeq Acc Id: NM_001191562   ⟹   NP_001178491
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81229,099,741 - 229,984,172 (+)NCBI
mRatBN7.21219,673,200 - 220,557,610 (+)NCBI
Rnor_6.01239,741,572 - 240,757,583 (+)NCBI
Rnor_5.01247,027,120 - 247,810,732 (+)NCBI
Rnor_5.01247,942,661 - 248,041,913 (+)NCBI
Celera1216,900,275 - 217,774,744 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001354180   ⟹   NP_001341109
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81229,435,510 - 229,984,172 (+)NCBI
mRatBN7.21220,008,970 - 220,557,610 (+)NCBI
RefSeq Acc Id: NP_001178491   ⟸   NM_001191562
- Peptide Label: isoform a
- UniProtKB: A0A8I6A0P1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018521   ⟸   ENSRNOT00000018521
RefSeq Acc Id: NP_001341109   ⟸   NM_001354180
- Peptide Label: isoform b
- UniProtKB: F1LN45 (UniProtKB/TrEMBL),   A0A8I6ALW5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000083902   ⟸   ENSRNOT00000113385
Ensembl Acc Id: ENSRNOP00000084148   ⟸   ENSRNOT00000109194
Ensembl Acc Id: ENSRNOP00000094201   ⟸   ENSRNOT00000115994
Ensembl Acc Id: ENSRNOP00000081604   ⟸   ENSRNOT00000098066
Ensembl Acc Id: ENSRNOP00000093587   ⟸   ENSRNOT00000114800
Ensembl Acc Id: ENSRNOP00000084016   ⟸   ENSRNOT00000114759
Protein Domains
Ion transport   TRPM SLOG   TRPM tetramerisation

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LN45-F1-model_v2 AlphaFold F1LN45 1-1661 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304888 AgrOrtholog
BioCyc Gene G2FUF-56142 BioCyc
Ensembl Genes ENSRNOG00000027770 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018521.7 UniProtKB/TrEMBL
  ENSRNOT00000098066.1 UniProtKB/TrEMBL
  ENSRNOT00000109194.1 UniProtKB/TrEMBL
  ENSRNOT00000113385.1 UniProtKB/TrEMBL
  ENSRNOT00000114759.1 UniProtKB/TrEMBL
  ENSRNOT00000114800.1 UniProtKB/TrEMBL
  ENSRNOT00000115994.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.1010 UniProtKB/TrEMBL
InterPro Ion_trans_dom UniProtKB/TrEMBL
  TRPM UniProtKB/TrEMBL
  TRPM_SLOG UniProtKB/TrEMBL
  TRPM_tetra UniProtKB/TrEMBL
  TRPM_tetra_sf UniProtKB/TrEMBL
NCBI Gene 309407 ENTREZGENE
PANTHER PTHR13800:SF7 UniProtKB/TrEMBL
  TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 UniProtKB/TrEMBL
Pfam Ion_trans UniProtKB/TrEMBL
  LSDAT_euk UniProtKB/TrEMBL
  TRPM_tetra UniProtKB/TrEMBL
PhenoGen Trpm3 PhenoGen
RatGTEx ENSRNOG00000027770 RatGTEx
UniProt A0A8I5ZWW2_RAT UniProtKB/TrEMBL
  A0A8I6A0D5_RAT UniProtKB/TrEMBL
  A0A8I6A0P1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALW5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G666_RAT UniProtKB/TrEMBL
  A0A8I6GL22_RAT UniProtKB/TrEMBL
  A7L636_RAT UniProtKB/TrEMBL
  A7L637_RAT UniProtKB/TrEMBL
  A7L638_RAT UniProtKB/TrEMBL
  F1LN45 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Trpm3  transient receptor potential cation channel, subfamily M, member 3   Trpm3_predicted  transient receptor potential cation channel, subfamily M, member 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Trpm3_predicted  transient receptor potential cation channel, subfamily M, member 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED