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Gene: Traf3ip3 (TRAF3 interacting protein 3) Rattus norvegicus

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Symbol:

Traf3ip3

Name:

TRAF3 interacting protein 3

RGD ID:

1304848

Description:

Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in cytoplasmic pattern recognition receptor signaling pathway. Predicted to act upstream of or within antiviral innate immune response; cellular response to cytokine stimulus; and positive regulation of type I interferon production. Predicted to be active in mitochondrial outer membrane. Orthologous to human TRAF3IP3 (TRAF3 interacting protein 3); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC360900; MGC108851; RGD1304848; similar to RIKEN cDNA 6030423D04; TRAF3-interacting JNK-activating modulator

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TRAF3IP3 (TRAF3 interacting protein 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Traf3ip3 (TRAF3 interacting protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Traf3ip3 (TRAF3 interacting protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TRAF3IP3 (TRAF3 interacting protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TRAF3IP3 (TRAF3 interacting protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Traf3ip3 (TRAF3 interacting protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TRAF3IP3 (TRAF3 interacting protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TRAF3IP3 (TRAF3 interacting protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Traf3ip3 (TRAF3 interacting protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Traf3ip3 (TRAF3 interacting protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TRAF3IP3 (TRAF3 interacting protein 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Traf3ip3 (TRAF3 interacting protein 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	FAR10	Alliance	DIOPT (OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	M4.1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Slmap	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	VPS64	Alliance	DIOPT (OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	traf3ip3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	traf3ip3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	107,223,499 - 107,248,358 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	107,223,502 - 107,248,155 (-)	Ensembl				GRCr8
mRatBN7.2	13	104,694,802 - 104,719,655 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	104,694,805 - 104,719,673 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	107,212,415 - 107,237,070 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	108,596,267 - 108,620,922 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	105,814,233 - 105,838,881 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	111,892,744 - 111,917,368 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	111,892,760 - 111,917,587 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	116,447,648 - 116,473,153 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	109,009,596 - 109,034,265 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	104,125,051 - 104,149,628 (-)	NCBI		Celera
RGSC_v3.1	13	109,198,700 - 109,223,369 (-)	NCBI
Cytogenetic Map	13	q27	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4,4'-sulfonyldiphenol (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

alpha-Zearalanol (EXP)

amphetamine (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP,ISO)

buta-1,3-diene (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroprene (ISO)

chrysene (ISO)

crocidolite asbestos (ISO)

diclofenac (EXP)

dimethylarsinic acid (ISO)

diuron (ISO)

gentamycin (EXP)

glycidol (EXP)

GSK-J4 (ISO)

isotretinoin (ISO)

lipopolysaccharide (ISO)

methyl methanesulfonate (ISO)

methylarsonic acid (ISO)

nickel atom (ISO)

nitrates (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

testosterone (EXP)

tetraphene (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

triphenyl phosphate (ISO)

trovafloxacin (ISO)

tungsten (ISO)

vinclozolin (EXP)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

antiviral innate immune response (ISO)

cellular response to interferon-alpha (ISO)

cellular response to interferon-beta (ISO)

cytoplasmic pattern recognition receptor signaling pathway (IEA,ISO)

positive regulation of interferon-alpha production (ISO)

positive regulation of interferon-beta production (ISO)

positive regulation of type I interferon production (IEA,ISO)

Cellular Component

endoplasmic reticulum membrane (IEA,ISO)

Golgi membrane (IEA,ISO)

mitochondrial membrane (IEA,ISO)

mitochondrial outer membrane (IEA,ISO)

mitochondrion (IEA,ISO)

Molecular Function

molecular adaptor activity (IEA,ISO)

protein binding (ISO)

protein-macromolecule adaptor activity (IEA,ISO)

zf-TRAF domain binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics

Comparative Map Data

Traf3ip3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	107,223,499 - 107,248,358 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	107,223,502 - 107,248,155 (-)	Ensembl				GRCr8
mRatBN7.2	13	104,694,802 - 104,719,655 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	104,694,805 - 104,719,673 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	107,212,415 - 107,237,070 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	108,596,267 - 108,620,922 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	105,814,233 - 105,838,881 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	111,892,744 - 111,917,368 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	111,892,760 - 111,917,587 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	116,447,648 - 116,473,153 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	109,009,596 - 109,034,265 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	104,125,051 - 104,149,628 (-)	NCBI		Celera
RGSC_v3.1	13	109,198,700 - 109,223,369 (-)	NCBI
Cytogenetic Map	13	q27	NCBI

TRAF3IP3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	209,756,053 - 209,782,310 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	209,756,032 - 209,782,320 (+)	Ensembl			hg38	GRCh38
GRCh37	1	209,929,398 - 209,955,655 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	207,996,147 - 208,022,288 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	183,160,288 - 183,186,562 (+)	NCBI		Celera
Cytogenetic Map	1	q32.2	NCBI
HuRef	1	180,604,609 - 180,630,813 (+)	NCBI		HuRef
CHM1_1	1	211,201,767 - 211,227,998 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	209,002,813 - 209,029,078 (+)	NCBI		T2T-CHM13v2.0

Traf3ip3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	192,857,812 - 192,883,854 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	192,857,761 - 192,884,011 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	193,175,504 - 193,201,546 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	193,175,453 - 193,201,703 (-)	Ensembl			mm10	GRCm38
MGSCv37	1	195,001,698 - 195,027,740 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	194,876,230 - 194,902,210 (-)	NCBI		MGSCv36	mm8
Celera	1	200,050,588 - 200,076,654 (-)	NCBI		Celera
Cytogenetic Map	1	H6	NCBI
cM Map	1	97.62	NCBI

Traf3ip3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955489	2,440,455 - 2,464,700 (-)	Ensembl
ChiLan1.0	NW_004955489	2,442,319 - 2,468,683 (-)	NCBI	ChiLan1.0	ChiLan1.0

TRAF3IP3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	39,619,080 - 39,645,157 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	39,585,244 - 39,611,411 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	185,332,556 - 185,358,653 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	190,137,880 - 190,162,773 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	190,141,928 - 190,162,598 (+)	Ensembl			panPan2	panpan1.1

TRAF3IP3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	8,421,163 - 8,444,399 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	8,421,788 - 8,444,397 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	7,998,513 - 8,021,530 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	8,121,697 - 8,144,997 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	8,121,700 - 8,144,989 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	8,051,436 - 8,074,680 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	8,148,468 - 8,171,704 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	8,290,781 - 8,309,799 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0
UU_Cfam_GSD_1.0	7	8,209,919 - 8,233,156 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Traf3ip3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	66,074,753 - 66,095,407 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936557	3,313,244 - 3,344,819 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936557	3,315,035 - 3,337,763 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRAF3IP3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	133,190,014 - 133,214,207 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	9	133,190,020 - 133,214,209 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

TRAF3IP3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	19,671,531 - 19,699,737 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	19,671,693 - 19,695,356 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666055	20,270,926 - 20,298,064 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Traf3ip3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624807	2,214,449 - 2,235,048 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624807	2,214,288 - 2,239,449 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Traf3ip3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	10	71,157,747 - 71,180,218 (-)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	57
Count of miRNA genes:	44
Interacting mature miRNAs:	55
Transcripts:	ENSRNOT00000007649
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
738027	Lnnr6	Liver neoplastic nodule remodeling QTL 6	3.3		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	65613454	109350286	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
7387280	Uae43	Urinary albumin excretion QTL 43	5.69	0.4174	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	68983334	109350286	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	67635937	109350286	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	67635937	109350286	Rat
1576318	Schws5	Schwannoma susceptibility QTL 5		0.0351	nervous system integrity trait (VT:0010566)	post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)	13	64497900	109350286	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	64375743	109350286	Rat
8655951	Rf63	Renal function QTL 63	12.2		blood urea nitrogen amount (VT:0005265)	plasma urea nitrogen level (CMO:0000586)	13	71610804	109350286	Rat
4889606	Gluco63	Glucose level QTL 63	2.86	0.003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	83286150	109350286	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	67635937	109350286	Rat

Markers in Region

D13Got107

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	13	107,243,889 - 107,244,053 (+)	Marker Load Pipeline
mRatBN7.2	13	104,715,188 - 104,715,352 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	111,913,103 - 111,913,266	NCBI	Rnor6.0
Rnor_5.0	13	116,468,683 - 116,468,846	UniSTS	Rnor5.0
RGSC_v3.4	13	109,030,000 - 109,030,163	UniSTS	RGSC3.4
RGSC_v3.4	13	109,029,999 - 109,030,163	RGD	RGSC3.4
RGSC_v3.1	13	109,219,103 - 109,219,267	RGD
RH 3.4 Map	13	769.8	UniSTS
RH 3.4 Map	13	769.8	RGD
RH 2.0 Map	13	780.1	RGD
Cytogenetic Map	13	q27	UniSTS

RH131251

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	104,694,963 - 104,695,163 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	111,892,906 - 111,893,105	NCBI	Rnor6.0
Rnor_5.0	13	116,447,810 - 116,448,009	UniSTS	Rnor5.0
RGSC_v3.4	13	109,009,758 - 109,009,957	UniSTS	RGSC3.4
Celera	13	104,125,213 - 104,125,412	UniSTS
RH 3.4 Map	13	795.6	UniSTS
Cytogenetic Map	13	q27	UniSTS

RH140005

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	104,698,091 - 104,698,287 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	111,896,006 - 111,896,201	NCBI	Rnor6.0
Rnor_5.0	13	116,451,579 - 116,451,774	UniSTS	Rnor5.0
RGSC_v3.4	13	109,012,903 - 109,013,098	UniSTS	RGSC3.4
Celera	13	104,128,348 - 104,128,543	UniSTS
RH 3.4 Map	13	758.0	UniSTS
Cytogenetic Map	13	q27	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	92	59	6	356	192	11	135	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001014132	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429806	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769865	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090944	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090945	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC126166	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC089843	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000007649 ⟹ ENSRNOP00000007649

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	107,223,502 - 107,248,155 (-)	Ensembl
mRatBN7.2 Ensembl	13	104,694,805 - 104,719,454 (-)	Ensembl
Rnor_6.0 Ensembl	13	111,892,760 - 111,917,587 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114180 ⟹ ENSRNOP00000095182

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	107,223,502 - 107,245,758 (-)	Ensembl
mRatBN7.2 Ensembl	13	104,694,805 - 104,719,454 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114304 ⟹ ENSRNOP00000094100

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	104,694,805 - 104,719,673 (-)	Ensembl

RefSeq Acc Id:

NM_001014132 ⟹ NP_001014154

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	107,223,499 - 107,248,155 (-)	NCBI
mRatBN7.2	13	104,694,802 - 104,719,454 (-)	NCBI
Rnor_6.0	13	111,892,744 - 111,917,368 (-)	NCBI
Rnor_5.0	13	116,447,648 - 116,473,153 (-)	NCBI
RGSC_v3.4	13	109,009,596 - 109,034,265 (-)	RGD
Celera	13	104,125,051 - 104,149,628 (-)	RGD

Sequence:

show sequence

GGCTCTCCCGAGACACTTGAGACAGAGCCTGGGACCTGAGATCCAAGCAGCTGTCTAAGGAAAG
TAAGCCAAGCACAACAGGTGCTCGGGAGGCCACCATGATCGGCTCAAACTCCAGGTCCTTCCCT
AGCTTGGCTCGGTGGGCCGAGAGCTATGAGGCCAAGTGTGAGCGGCGTCAGGAGGCCCGAGAAA
GCCTCCGCCGCCGCCGCAATGAGACCACCTGCCGCCAGCCAGGGAAGGTGCTGCGGACTCAACA
CAAGGAACACCTTCAGCGAGCTCGGCAGCTACAGTTCCTCAGAAGGAGAAACCTGGAAGAAGAG
AAGAAAGGTCAATCCAGGGAGCAAAGGCCCTCCAGCAAGACAGATGGAGGAACAGGCCAAGTGT
CTATCCTCAAGAAGTCCGGGCCTGGAGCCAACAGGACCTCTTTCCCTGGACAGCAGGAAACAGG
GATATGCTCCGAGGTTTTCCCAGCCTTGTGTCATCCCCCCTCAGGCATCCAGAGAGATCTGGAT
GACCACCATGTTTCCCATGGAAGAGCCTTTCCACCACAGGACTCTGACACCATGAAGCCACACA
GACACCACCAGGGTACTCAGACAAAGGCAGAAGAGGCATGGCCAACAAGAAAGAATGATGCCAG
TCAGCAAACCAACTGTGGAGTTGCCGTCCTAGACAAGGACATCATTCAACTCTCTGAATACCTC
AAAGAAGCCTTACAAAGGGAGCTGATCCTAAAACAAAAAATGGTGATTCTCCAGGACCTCCTGC
CTGCCCTGATCCGGGCCTCTGACAGCTCTTGGAAGGGACAGCTTAATGAAGACAAACTGAAGGG
CAAACTAAGATCCCTAGAAAACCAGCTCTACACCTGCCTGCAGAAACACTCCCCCTGGGGGATG
AAAAAGGTACTGCTGGACATGGAGAACCAGAGGAGCAGTTACGAGCAGAAGGCTAAGGCATCAC
TGCAGAAAGTGCTGGAGGAGAAAATGTGTGCCGAGCAGCAACTGCAGAGGGCGCAGCTGTCCCT
GGCTGTGGCAGAGCAGAAGTGTCAGGAGTGGAAGAGTCAGTACGAGGCTCTTAAGGAGGACTGG
AGGACCCTAGGGGACCAGCACAGGGAGCTGGAGAGCCAACTGCATGTGCTTCAGTCTAAACTAC
AGGGAGCAGACAGCAGAGACTCACAGATGAGCCAGGCCCTACGACTTTTAGAAAATGAACACCA
GGAGCTGCAGACCAAACTCGAGAGCCTGCAGGGAGACCGAGAGCAGCAGAGCTCTGAAACCCAG
GACCTACAAGATCAACTAAAGAAGTCCGAGGAGGAGAGACAAGCCCTGATGAGCAGAGTTCAAC
AGCTACAGAGTCTGCTTCAGAATCAATCCTTACAACTTCGAGAACAGGAGAAGCTCTTAAAGAA
AGATCAGGGTTTGCCTGTGTGGAATCCAAAGCTCTCCTTTGATGAAGTGAAGCCTGAGGGTACA
GGAAAGGAGAAAGTCGAGGAGCTCAGAGACCAACTACAAAAGGAGACATATCAGCTCCAGGCCA
AGGAAAAGGAGCGGCAGTGTAGCCAATGGCTCCCAGCGCTGGTGGTGGTGATTGCTACAGCACT
GGCCGTGTTCCTGGCAAACAAAGGCAACCTGGTCATCTGAAGAACTCCCGGCATCTATCTGAAG
TAAAATTCAGAAGCAAACAACTCCATGAAAAAACTTGAGGTTTGGTACTTTATAGCTTAGGTTT
TCCCTCCAAATGAATCTGGACCCCTAGCTTTATTTTTCCCACCATGCTGTAAATAAACTTTGCC
TCACAAGACTGCTCTTTAGAGCTGTGTATTCCTGAGAAGTAAACCACAAGTGTGGCCCTTAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_008769865 ⟹ XP_008768087

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	107,223,554 - 107,248,354 (-)	NCBI
mRatBN7.2	13	104,694,857 - 104,719,654 (-)	NCBI
Rnor_6.0	13	111,892,799 - 111,915,404 (-)	NCBI

Sequence:

show sequence

GGACCGAACCCAGGGCCTTGCGCTTGCTAGGCAAGGGCTCTACCGCTGAGCTAAATCTCCAACC
CCTGAGCCAGATTCTCTGAAGTGAACCAACACCAAGCATTTTGAAGGCTCTCAGCTAACTGACT
GACTTGATCAGCAGCTGAGAGTCAGATACCCCAGCACTAGATACACAGTAGATGACAAAGAGGA
AGGTCGGGGTGGAGTGATGGAGGAATTAGAGCAGGTTTCCCCTAGGTCATGCCAGTCCAGAGCC
ACAAGATGGCTGCTGAGAGCTAGGCGTGGAACAGAAAGTGCGAGTCACAAACCAGGTCACTTCC
TGAAGGGTCGTGGCTATCCTGCTAGGTCTCCAGAAGTGTCACTTAGCAAGAGATAGTAAAGATG
ACATCATCTTTCTTTTTTAGACTGGGAGATAAAGTGGGCCGGGCTGTCCACAGTTGCACGTGGC
TGAGGTTCATTGTGGCCACTGTTATTTCTTCCTCGTGTTCCCTCACTTAGAGGCATCTAGTCCG
GAGGAAGGGGTTCCAGAGAGACCCGTCCACTTTAGGAGATTAGCGCTCGAGGAAACCGGAAACC
TGGATTGCACCAGTTCATGCCTGGGAGTCCTAACCCTAGGTTTTCAACACATAGGAATGGAGCC
CCGTACTATTCCTACCCTGACCCAGGGAGATAGACTGTCAGTTTTCAGCCCATCTTTTGACTCC
TCCCTCTTGGCATCTGGCAGATCCAAGCAGCTGTCTAAGGAAAGTAAGCCAAGCACAACAGGTG
CTCGGGAGGCCACCATGATCGGCTCAAACTCCAGGTCCTTCCCTAGCTTGGCTCGGTGGGCCGA
GAGCTATGAGGCCAAGTGTGAGCGGCGTCAGGAGGCCCGAGAAAGCCTCCGCCGCCGCCGCAAT
GAGACCACCTGCCGCCAGCCAGGGAAGGTGCTGCGGACTCAACACAAGGAACACCTTCAGCGAG
CTCGGCAGCTACAGTTCCTCAGAAGGAGAAACCTGGAAGAAGAGAAGAAAGGTCAATCCAGGGA
GCAAAGGCCCTCCAGCAAGACAGATGGAGGAACAGGCCAAGTGTCTATCCTCAAGAAGTCCGGG
CCTGGAGCCAACAGGACCTCTTTCCCTGGACAGCAGGAAACAGGGATATGCTCCGAGGTTTTCC
CAGCCTTGTGTCATCCCCCCTCAGGCATCCAGAGAGATCTGGATGACCACCATGTTTCCCATGG
AAGAGCCTTTCCACCACAGGACTCTGACACCATGAAGCCACACAGACACCACCAGGGTACTCAG
ACAAAGGCAGAAGAGGCATGGCCAACAAGAAAGAATGATGCCAGTCAGCAAACCAACTGTGGAG
TTGCCGTCCTAGACAAGGACATCATTCAACTCTCTGAATACCTCAAAGAAGCCTTACAAAGGGA
GCTGATCCTAAAACAAAAAATGGTGATTCTCCAGGACCTCCTGCCTGCCCTGATCCGGGCCTCT
GACAGCTCTTGGAAGGGACAGCTTAATGAAGACAAACTGAAGGGCAAACTAAGATCCCTAGAAA
ACCAGCTCTACACCTGCCTGCAGAAACACTCCCCCTGGGGGATGAAAAAGGTACTGCTGGACAT
GGAGAACCAGAGGAGCAGTTACGAGCAGAAGGCTAAGGCATCACTGCAGAAAGTGCTGGAGGAG
AAAATGTGTGCCGAGCAGCAACTGCAGAGGGCGCAGCTGTCCCTGGCTGTGGCAGAGCAGAAGT
GTCAGGAGTGGAAGAGTCAGTACGAGGCTCTTAAGGAGGACTGGAGGACCCTAGGGGACCAGCA
CAGGGAGCTGGAGAGCCAACTGCATGTGCTTCAGTCTAAACTACAGGGAGCAGACAGCAGAGAC
TCACAGATGAGCCAGGCCCTACGACTTTTAGAAAATGAACACCAGGAGCTGCAGACCAAACTCG
AGAGCCTGCAGGGAGACCGAGAGCAGCAGAGCTCTGAAACCCAGGACCTACAAGATCAACTAAA
GAAGTCCGAGGAGGAGAGACAAGCCCTGATGAGCAGAGTTCAACAGCTACAGAGTCTGCTTCAG
AATCAATCCTTACAACTTCGAGAACAGGAGAAGCTCTTAAAGAAAGATCAGGGTTTGCCTGTGT
GGAATCCAAAGCTCTCCTTTGATGAAGTGAAGCCTGAGGGTACAGGAAAGGAGAAAGTCGAGGA
GCTCAGAGACCAACTACAAAAGGAGACATATCAGCTCCAGGCCAAGGAAAAGGAGCGGCAGTGT
AGCCAATGGCTCCCAGCGCTGGTGGTGGTGATTGCTACAGCACTGGCCGTGTTCCTGGCAAACA
AAGGCAACCTGGTCATCTGAAGAACTCCCGGCATCTATCTGAAGTAAAATTCAGAAGCAAACAA
CTCCATGAAAAAACTTGAGGTTTGGTACTTTATAGCTTAGGTTTTCCCTCCAAATGAATCTGGA
CCCCTAGCTTTATTTTTCCCACCATGCTGTAAATAAACTTTGCCTCACAAGA

hide sequence

RefSeq Acc Id:

XM_039090944 ⟹ XP_038946872

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	107,223,554 - 107,248,358 (-)	NCBI
mRatBN7.2	13	104,694,859 - 104,719,655 (-)	NCBI

RefSeq Acc Id:

XM_039090945 ⟹ XP_038946873

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	107,223,554 - 107,248,354 (-)	NCBI
mRatBN7.2	13	104,694,857 - 104,719,653 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001014154	(Get FASTA)	NCBI Sequence Viewer
	NP_001416735	(Get FASTA)	NCBI Sequence Viewer
	XP_008768087	(Get FASTA)	NCBI Sequence Viewer
	XP_038946872	(Get FASTA)	NCBI Sequence Viewer
	XP_038946873	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH89843	(Get FASTA)	NCBI Sequence Viewer
	EDL95029	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000007649
	ENSRNOP00000007649.4
	ENSRNOP00000095182.2

RefSeq Acc Id:

NP_001014154 ⟸ NM_001014132

- UniProtKB:

Q5FVQ1 (UniProtKB/TrEMBL), A6JH23 (UniProtKB/TrEMBL), A0A8I6AKZ2 (UniProtKB/TrEMBL), F7FMH4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MIGSNSRSFPSLARWAESYEAKCERRQEARESLRRRRNETTCRQPGKVLRTQHKEHLQRARQLQ
FLRRRNLEEEKKGQSREQRPSSKTDGGTGQVSILKKSGPGANRTSFPGQQETGICSEVFPALCH
PPSGIQRDLDDHHVSHGRAFPPQDSDTMKPHRHHQGTQTKAEEAWPTRKNDASQQTNCGVAVLD
KDIIQLSEYLKEALQRELILKQKMVILQDLLPALIRASDSSWKGQLNEDKLKGKLRSLENQLYT
CLQKHSPWGMKKVLLDMENQRSSYEQKAKASLQKVLEEKMCAEQQLQRAQLSLAVAEQKCQEWK
SQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADSRDSQMSQALRLLENEHQELQTKLESLQG
DREQQSSETQDLQDQLKKSEEERQALMSRVQQLQSLLQNQSLQLREQEKLLKKDQGLPVWNPKL
SFDEVKPEGTGKEKVEELRDQLQKETYQLQAKEKERQCSQWLPALVVVIATALAVFLANKGNLV
I

hide sequence

RefSeq Acc Id:

XP_008768087 ⟸ XM_008769865

- Peptide Label:

isoform X2

- Sequence:

show sequence

MEPRTIPTLTQGDRLSVFSPSFDSSLLASGRSKQLSKESKPSTTGAREATMIGSNSRSFPSLAR
WAESYEAKCERRQEARESLRRRRNETTCRQPGKVLRTQHKEHLQRARQLQFLRRRNLEEEKKGQ
SREQRPSSKTDGGTGQVSILKKSGPGANRTSFPGQQETGICSEVFPALCHPPSGIQRDLDDHHV
SHGRAFPPQDSDTMKPHRHHQGTQTKAEEAWPTRKNDASQQTNCGVAVLDKDIIQLSEYLKEAL
QRELILKQKMVILQDLLPALIRASDSSWKGQLNEDKLKGKLRSLENQLYTCLQKHSPWGMKKVL
LDMENQRSSYEQKAKASLQKVLEEKMCAEQQLQRAQLSLAVAEQKCQEWKSQYEALKEDWRTLG
DQHRELESQLHVLQSKLQGADSRDSQMSQALRLLENEHQELQTKLESLQGDREQQSSETQDLQD
QLKKSEEERQALMSRVQQLQSLLQNQSLQLREQEKLLKKDQGLPVWNPKLSFDEVKPEGTGKEK
VEELRDQLQKETYQLQAKEKERQCSQWLPALVVVIATALAVFLANKGNLVI

hide sequence

Ensembl Acc Id:

ENSRNOP00000007649 ⟸ ENSRNOT00000007649

RefSeq Acc Id:	XP_038946873 ⟸ XM_039090945
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038946872 ⟸ XM_039090944
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000094100 ⟸ ENSRNOT00000114304

Ensembl Acc Id:

ENSRNOP00000095182 ⟸ ENSRNOT00000114180

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5FVQ1-F1-model_v2	AlphaFold	Q5FVQ1	1-513	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304848	AgrOrtholog
BioCyc Gene	G2FUF-16788	BioCyc
Ensembl Genes	ENSRNOG00000005565	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000007649	ENTREZGENE
	ENSRNOT00000007649.7	UniProtKB/TrEMBL
	ENSRNOT00000114180.2	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7368358	IMAGE-MGC_LOAD
InterPro	Cent_Immune-Sig_Mod	UniProtKB/TrEMBL
KEGG Report	rno:360900	UniProtKB/TrEMBL
MGC_CLONE	MGC:108851	IMAGE-MGC_LOAD
NCBI Gene	360900	ENTREZGENE
PANTHER	CENTROSOMAL PROTEIN OF 170 KDA	UniProtKB/TrEMBL
	TRAF3-INTERACTING JNK-ACTIVATING MODULATOR	UniProtKB/TrEMBL
PhenoGen	Traf3ip3	PhenoGen
RatGTEx	ENSRNOG00000005565	RatGTEx
UniProt	A0A8I6AKZ2	ENTREZGENE, UniProtKB/TrEMBL
	A6JH23	ENTREZGENE, UniProtKB/TrEMBL
	F7FMH4	ENTREZGENE, UniProtKB/TrEMBL
	Q5FVQ1	ENTREZGENE
UniProt Secondary	Q5FVQ1	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Traf3ip3	TRAF3 interacting protein 3	RGD1304848	similar to RIKEN cDNA 6030423D04	Symbol and Name updated	1299863	APPROVED
2005-12-06	RGD1304848	similar to RIKEN cDNA 6030423D04	RGD1304848_predicted	similar to RIKEN cDNA 6030423D04 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1304848_predicted	similar to RIKEN cDNA 6030423D04 (predicted)	LOC360900_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC360900_predicted	similar to RIKEN cDNA 6030423D04 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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