Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Calhm6 | Rat | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of FAM26F mRNA | CTD | PMID:32741896 | Calhm6 | Rat | 17beta-estradiol 3-benzoate | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of FAM26F mRNA | CTD | PMID:32741896 | Calhm6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Calhm6 (Mus musculus) | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of CALHM6 mRNA | CTD | PMID:25975270 | Calhm6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CALHM6 mRNA | CTD | PMID:34747641 | Calhm6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Calhm6 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of CALHM6 mRNA | CTD | PMID:26377647 | Calhm6 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Calhm6 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:38648751 | Calhm6 | Rat | 2-hydroxypropanoic acid | increases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of CALHM6 mRNA | CTD | PMID:30851411 | Calhm6 | Rat | 2-palmitoylglycerol | increases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of CALHM6 mRNA | CTD | PMID:37199045 | Calhm6 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Calhm6 (Mus musculus) | 6480464 | Fenretinide results in increased expression of CALHM6 mRNA | CTD | PMID:28973697 | Calhm6 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of CALHM6 mRNA | CTD | PMID:31881176 | Calhm6 | Rat | alpha-Zearalanol | increases expression | EXP | | 6480464 | Zeranol results in increased expression of CALHM6 mRNA | CTD | PMID:35163327 | Calhm6 | Rat | antirheumatic drug | decreases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of CALHM6 mRNA | CTD | PMID:24449571 | Calhm6 | Rat | avobenzone | increases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | avobenzone results in increased expression of CALHM6 mRNA | CTD | PMID:31016361 | Calhm6 | Rat | belinostat | decreases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | belinostat results in decreased expression of CALHM6 mRNA | CTD | PMID:27188386 | Calhm6 | Rat | benzo[a]pyrene | increases methylation | ISO | CALHM6 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of FAM26F promoter | CTD | PMID:27901495 | Calhm6 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of FAM26F mRNA | CTD | PMID:31163220 | Calhm6 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of CALHM6 mRNA | CTD | PMID:25181051 | Calhm6 | Rat | bisphenol A | increases expression | ISO | Calhm6 (Mus musculus) | 6480464 | bisphenol A results in increased expression of CALHM6 mRNA | CTD | PMID:38074096 | Calhm6 | Rat | carbon nanotube | increases expression | ISO | Calhm6 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Calhm6 | Rat | chloroprene | decreases expression | ISO | Calhm6 (Mus musculus) | 6480464 | Chloroprene results in decreased expression of CALHM6 mRNA | CTD | PMID:23125180 | Calhm6 | Rat | dioxygen | increases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | Oxygen deficiency results in increased expression of CALHM6 mRNA | CTD | PMID:26516004 | Calhm6 | Rat | dorsomorphin | multiple interactions | ISO | CALHM6 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CALHM6 mRNA | CTD | PMID:27188386 | Calhm6 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of CALHM6 mRNA | CTD | PMID:29391264 | Calhm6 | Rat | entinostat | decreases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | entinostat results in decreased expression of CALHM6 mRNA | CTD | PMID:27188386 | Calhm6 | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of CALHM6 mRNA | CTD | PMID:30307764 | Calhm6 | Rat | formaldehyde | decreases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of CALHM6 mRNA | CTD | PMID:27664576 | Calhm6 | Rat | Genipin | multiple interactions | ISO | Calhm6 (Mus musculus) | 6480464 | genipin inhibits the reaction [Lipopolysaccharides results in increased expression of CALHM6 mRNA] | CTD | PMID:22687549 | Calhm6 | Rat | hydroquinone | decreases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | hydroquinone results in decreased expression of CALHM6 mRNA | CTD | PMID:31256213 | Calhm6 | Rat | lipopolysaccharide | multiple interactions | ISO | Calhm6 (Mus musculus) | 6480464 | genipin inhibits the reaction [Lipopolysaccharides results in increased expression of CALHM6 mRNA] | CTD | PMID:22687549 | Calhm6 | Rat | lipopolysaccharide | increases expression | ISO | Calhm6 (Mus musculus) | 6480464 | Lipopolysaccharides results in increased expression of CALHM6 mRNA | CTD | PMID:22687549 and PMID:27339419 | Calhm6 | Rat | Monobutylphthalate | increases expression | EXP | | 6480464 | monobutyl phthalate results in increased expression of CALHM6 mRNA | CTD | PMID:29162477 | Calhm6 | Rat | Muraglitazar | decreases expression | EXP | | 6480464 | muraglitazar results in decreased expression of CALHM6 mRNA | CTD | PMID:21515302 | Calhm6 | Rat | nickel atom | increases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | Nickel results in increased expression of CALHM6 mRNA | CTD | PMID:24768652 and PMID:25583101 | Calhm6 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of CALHM6 mRNA | CTD | PMID:25729387 | Calhm6 | Rat | phenylmercury acetate | increases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of CALHM6 mRNA | CTD | PMID:26272509 | Calhm6 | Rat | phenylmercury acetate | multiple interactions | ISO | CALHM6 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CALHM6 mRNA | CTD | PMID:27188386 | Calhm6 | Rat | progesterone | increases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | Progesterone results in increased expression of CALHM6 mRNA | CTD | PMID:21540246 | Calhm6 | Rat | rac-lactic acid | increases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of CALHM6 mRNA | CTD | PMID:30851411 | Calhm6 | Rat | SB 431542 | multiple interactions | ISO | CALHM6 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CALHM6 mRNA | CTD | PMID:27188386 | Calhm6 | Rat | silicon dioxide | increases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of CALHM6 mRNA | CTD | PMID:23806026 | Calhm6 | Rat | silicon dioxide | increases expression | ISO | Calhm6 (Mus musculus) | 6480464 | Silicon Dioxide results in increased expression of CALHM6 mRNA and Silicon Dioxide results in increased expression of FAM26F mRNA | CTD | PMID:23221170 and PMID:29341224 | Calhm6 | Rat | Tesaglitazar | decreases expression | EXP | | 6480464 | tesaglitazar results in decreased expression of CALHM6 mRNA | CTD | PMID:21515302 | Calhm6 | Rat | testosterone | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of FAM26F mRNA | CTD | PMID:32741896 | Calhm6 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of CALHM6 mRNA | CTD | PMID:31150632 | Calhm6 | Rat | tetrachloromethane | affects expression | ISO | Calhm6 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of CALHM6 mRNA | CTD | PMID:31919559 | Calhm6 | Rat | tetrachloromethane | increases expression | ISO | Calhm6 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of CALHM6 mRNA | CTD | PMID:27339419 | Calhm6 | Rat | titanium dioxide | increases methylation | ISO | Calhm6 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of FAM26F gene | CTD | PMID:35295148 | Calhm6 | Rat | titanium dioxide | increases expression | ISO | Calhm6 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of CALHM6 mRNA | CTD | PMID:35295148 | Calhm6 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of CALHM6 mRNA | CTD | PMID:25729387 | Calhm6 | Rat | triphenyl phosphate | affects expression | ISO | CALHM6 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of CALHM6 mRNA | CTD | PMID:37042841 | Calhm6 | Rat | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of CALHM6 mRNA | CTD | PMID:21515302 | Calhm6 | Rat | trovafloxacin | decreases expression | ISO | Calhm6 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of FAM26F mRNA | CTD | PMID:35537566 | Calhm6 | Rat | valproic acid | decreases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of CALHM6 mRNA | CTD | PMID:23179753 and PMID:27188386 | Calhm6 | Rat | valproic acid | increases expression | ISO | CALHM6 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CALHM6 mRNA | CTD | PMID:28001369 | Calhm6 | Rat | valproic acid | increases methylation | ISO | CALHM6 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of CALHM6 gene | CTD | PMID:29154799 | |