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Gene: Mrpl15 (mitochondrial ribosomal protein L15) Rattus norvegicus

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Symbol:

Mrpl15

Name:

mitochondrial ribosomal protein L15

RGD ID:

1304796

Description:

Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Orthologous to human MRPL15 (mitochondrial ribosomal protein L15); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

39S ribosomal protein L15, mitochondrial; large ribosomal subunit protein uL15m; LOC297799

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MRPL15 (mitochondrial ribosomal protein L15)	HGNC	Ensembl, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Mrpl15 (mitochondrial ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mrpl15 (mitochondrial ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MRPL15 (mitochondrial ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MRPL15 (mitochondrial ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mrpl15 (mitochondrial ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MRPL15 (mitochondrial ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MRPL15 (mitochondrial ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mrpl15 (mitochondrial ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Mrpl15 (mitochondrial ribosomal protein L15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	MRPL15 (mitochondrial ribosomal protein L15)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Mrpl15 (mitochondrial ribosomal protein L15)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mrpl15 (mitochondrial ribosomal protein L15)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	MRPL10	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	MRPL10	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	mRpL15	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	mrpl-15	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mrpl15	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	19,527,745 - 19,539,061 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	19,524,588 - 19,538,004 (+)	Ensembl				GRCr8
mRatBN7.2	5	14,729,961 - 14,741,276 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	14,729,979 - 14,741,276 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	16,924,207 - 16,935,288 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	18,537,717 - 18,548,790 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	18,258,877 - 18,269,950 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	14,609,656 - 14,620,965 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	14,609,674 - 14,620,965 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	19,392,153 - 19,403,455 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	14,932,623 - 14,943,904 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	14,101,085 - 14,112,172 (+)	NCBI		Celera
RGSC_v3.1	5	14,932,590 - 14,941,120 (+)	NCBI
Cytogenetic Map	5	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

buspirone (EXP)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

carbon nanotube (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

DDE (ISO)

dibenzo[a,l]pyrene (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

diclofenac (ISO)

dicrotophos (ISO)

dorsomorphin (ISO)

ethanol (ISO)

ibuprofen (ISO)

indometacin (EXP)

inulin (ISO)

ivermectin (ISO)

lead(0) (ISO)

maneb (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

paracetamol (ISO)

paraquat (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

propiconazole (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

testosterone (ISO)

thiram (ISO)

trichostatin A (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to leukemia inhibitory factor (ISO)

translation (IEA)

Cellular Component

large ribosomal subunit (IEA)

mitochondrial large ribosomal subunit (IBA,IEA,ISO)

mitochondrion (IEA,ISO)

ribonucleoprotein complex (IEA)

ribosome (IEA)

Molecular Function

protein binding (ISO)

structural constituent of ribosome (IBA,IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:14651853	PMID:18614015	PMID:20439489	PMID:22658674	PMID:22681889	PMID:25278503	PMID:28892042

Genomics

Comparative Map Data

Mrpl15
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	19,527,745 - 19,539,061 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	19,524,588 - 19,538,004 (+)	Ensembl				GRCr8
mRatBN7.2	5	14,729,961 - 14,741,276 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	14,729,979 - 14,741,276 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	16,924,207 - 16,935,288 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	18,537,717 - 18,548,790 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	18,258,877 - 18,269,950 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	14,609,656 - 14,620,965 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	14,609,674 - 14,620,965 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	19,392,153 - 19,403,455 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	14,932,623 - 14,943,904 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	14,101,085 - 14,112,172 (+)	NCBI		Celera
RGSC_v3.1	5	14,932,590 - 14,941,120 (+)	NCBI
Cytogenetic Map	5	q12	NCBI

MRPL15
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	54,135,241 - 54,148,514 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	54,135,183 - 54,149,588 (+)	Ensembl			hg38	GRCh38
GRCh37	8	55,047,801 - 55,061,074 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	55,210,334 - 55,223,014 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	8	55,210,333 - 55,223,011	NCBI
Celera	8	51,038,346 - 51,051,638 (+)	NCBI		Celera
Cytogenetic Map	8	q11.23	NCBI
HuRef	8	50,515,702 - 50,528,983 (+)	NCBI		HuRef
CHM1_1	8	55,099,593 - 55,112,890 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	54,512,543 - 54,525,817 (+)	NCBI		T2T-CHM13v2.0

Mrpl15
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	4,843,432 - 4,855,949 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	4,843,429 - 4,855,962 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	4,773,198 - 4,785,750 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	4,773,206 - 4,785,739 (-)	Ensembl			mm10	GRCm38
MGSCv37	1	4,763,279 - 4,775,807 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	4,763,290 - 4,775,791 (-)	NCBI		MGSCv36	mm8
Celera	1	4,785,037 - 4,797,586 (-)	NCBI		Celera
Cytogenetic Map	1	A1	NCBI
cM Map	1	1.79	NCBI

Mrpl15
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955454	13,398,478 - 13,406,794 (+)	Ensembl
ChiLan1.0	NW_004955454	13,398,479 - 13,404,353 (+)	NCBI	ChiLan1.0	ChiLan1.0

MRPL15
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	69,771,654 - 69,784,720 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	45,496,597 - 45,509,681 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	50,560,420 - 50,573,049 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	47,936,446 - 47,948,584 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	47,935,643 - 47,948,584 (+)	Ensembl			panPan2	panpan1.1

MRPL15
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	29	5,704,572 - 5,711,577 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	29	5,704,585 - 5,711,567 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	29	6,079,400 - 6,086,416 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	29	5,780,690 - 5,787,722 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	29	5,780,733 - 5,788,498 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	29	5,717,373 - 5,724,399 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	29	5,922,950 - 5,929,947 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	29	6,006,201 - 6,013,221 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Mrpl15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	73,787,265 - 73,799,049 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936496	986,131 - 1,001,648 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936496	986,442 - 997,440 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MRPL15
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	77,069,092 - 77,083,723 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	77,069,074 - 77,083,595 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	84,142,552 - 84,149,289 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MRPL15
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	50,201,805 - 50,214,534 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	50,201,829 - 50,216,206 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666039	91,720,535 - 91,733,740 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mrpl15
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624735	1,564,789 - 1,573,311 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624735	1,565,627 - 1,572,471 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Mrpl15
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	140,152,726 - 140,160,930 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Mrpl15
48 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	113
Count of miRNA genes:	97
Interacting mature miRNAs:	100
Transcripts:	ENSRNOT00000011619
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2293666	Bmd38	Bone mineral density QTL 38	4.4		femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	5	13731153	43590997	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	6922282	81330203	Rat
1300117	Hrtrt8	Heart rate QTL 8	3.49		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	8627230	52665523	Rat
7394712	Emca13	Estrogen-induced mammary cancer QTL 13			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	14606078	59606078	Rat
634305	Mamtr1	Mammary tumor resistance QTL 1		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	17576633	62576633	Rat
1578774	Tcas8	Tongue tumor susceptibility QTL 8	3.47		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	15707451	60707451	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	91770353	Rat
2312562	Pur18	Proteinuria QTL 18	2.6	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	5	6922282	37468560	Rat
8662454	Vetf3	Vascular elastic tissue fragility QTL 3	27.4		artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	5	7065535	74335773	Rat
1641903	Alcrsp3	Alcohol response QTL 3			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	17486080	62486080	Rat
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	87027358	Rat
631827	Alc4	Alcohol consumption QTL 4	3.5		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	5	12970480	25683802	Rat
2303577	Gluco47	Glucose level QTL 47	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	16520019	61520019	Rat
1641922	Alcrsp8	Alcohol response QTL 8			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	5	17486080	62486080	Rat
2313085	Bss59	Bone structure and strength QTL 59	2.9	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	5	8627230	53627230	Rat

Markers in Region

RH131914

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	14,738,850 - 14,739,045 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	14,618,540 - 14,618,734	NCBI	Rnor6.0
Rnor_5.0	5	19,401,030 - 19,401,224	UniSTS	Rnor5.0
RGSC_v3.4	5	14,941,479 - 14,941,673	UniSTS	RGSC3.4
Celera	5	14,109,747 - 14,109,941	UniSTS
Cytogenetic Map	5	q12	UniSTS

RH140473

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	14,738,061 - 14,738,153 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	14,617,751 - 14,617,842	NCBI	Rnor6.0
Rnor_5.0	5	19,400,241 - 19,400,332	UniSTS	Rnor5.0
RGSC_v3.4	5	14,940,690 - 14,940,781	UniSTS	RGSC3.4
Celera	5	14,108,958 - 14,109,049	UniSTS
Cytogenetic Map	5	q12	UniSTS

BE118926

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	14,739,999 - 14,740,166 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	14,619,689 - 14,619,855	NCBI	Rnor6.0
Rnor_5.0	5	19,402,179 - 19,402,345	UniSTS	Rnor5.0
RGSC_v3.4	5	14,942,628 - 14,942,794	UniSTS	RGSC3.4
Celera	5	14,110,896 - 14,111,062	UniSTS
Cytogenetic Map	5	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106633	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_174148	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC122627	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473984	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214289	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214529	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216110	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216137	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221067	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000011619 ⟹ ENSRNOP00000011619

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	14,729,995 - 14,741,276 (+)	Ensembl
Rnor_6.0 Ensembl	5	14,609,684 - 14,620,965 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000085621 ⟹ ENSRNOP00000074933

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	19,527,746 - 19,536,164 (+)	Ensembl
mRatBN7.2 Ensembl	5	14,729,979 - 14,738,570 (+)	Ensembl
Rnor_6.0 Ensembl	5	14,609,674 - 14,618,071 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115029 ⟹ ENSRNOP00000077151

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	19,527,746 - 19,530,606 (+)	Ensembl
mRatBN7.2 Ensembl	5	14,729,979 - 14,732,821 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000117082 ⟹ ENSRNOP00000085368

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	19,527,778 - 19,538,004 (+)	Ensembl
mRatBN7.2 Ensembl	5	14,730,016 - 14,739,065 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000148383 ⟹ ENSRNOP00000098827

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	19,524,588 - 19,538,004 (+)	Ensembl

RefSeq Acc Id:

NM_001106633 ⟹ NP_001100103

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	19,527,746 - 19,539,061 (+)	NCBI
mRatBN7.2	5	14,729,961 - 14,741,276 (+)	NCBI
Rnor_6.0	5	14,609,684 - 14,620,965 (+)	NCBI
Rnor_5.0	5	19,392,153 - 19,403,455 (+)	NCBI
RGSC_v3.4	5	14,932,623 - 14,943,904 (+)	RGD
Celera	5	14,101,085 - 14,112,172 (+)	RGD

Sequence:

show sequence

CGCCTTCTGGGCGCCCTTGAAAGGACCGTGGGCCATGGCTGGCATGGCGTTTGGCCGCGGGACC
AGTCTGGACCTTCTGCGGTCCTTGCCGAGAGTGAGCCTGGCCAATCTGAAGCCCAGTCTTAACT
CCAGAAAACGGGAAAGACGTCCAAGAGATCGGAGAAGAGGTAGGAAGTGTGGCAGAGGCCATAA
AGGAGAAAGACAGAGAGGAACCCGGCCCAGGCTGGGCTTTGAGGGAGGGCAGACTCCATTTTAC
ATCCGAATCCCAAAATATGGATTTAATGAAGGACATAGTTTCAGGCACCAGTATCAGCCTCTGA
GTCTCAGGAGACTACAGTATCTCATTGATTTAGGTCGAGTTGATCCAACTCAACCTATTGACTT
AACGCAGCTTGTGAATGGGAGAGGTGTGACCATCCAGCCACTTAAAAGGGATTATGGGGTCCAG
CTGGTTGAAGAGGGTGCTGATACTTTTCAAGCAAAAGTTAATATTGAGGTGCAGATGGCTTCAG
AATTAGCCATTGCTGCAATTGAAAAAAATGGTGGTGTTGTTACTACAGCCTTCTATGACCCAAG
AAGTCTAGGGGACTTGATGCCCTCTTCTGACTTCCATGGGTGCCAGGCGAGATACTCATTCATA
CACATAAGATAATAAAAAAGCCATTGAGAAAAGACTTCTGACCAGCATCTGGTATCCATGTGTG
CCTGCATCTGCCCTCACACCCCATTTCTGTACTAAGAGGGAAAATTTTGTTATGATCTGAATCC
TTGGTCTGTCTCTCTCTCTCTCTCTCTTTTTTTTTAACGTAAGTCACTTTTCTTTGGTAAGTAG
AAGGTTATTTCTAGGGTGAAAGTGTCACCTGGGGTAGAGGAGAGTGGGCTCTGATGTTAGTGCG
AGTCCCGTGAGGGTTGTCTTCTGTGGTACCTTGCTCAGGCCACTGCACTGTGTAGCTTTGCTCA
TTACACGCCTGTACCTGCAGAGCCATCTGGATGAGACACGTGACTAGGGTTTAAAGCAGAACTA
GATTTGGGACTTTGGCATGCAATTTATTCTCTGCCTCAGTTTCACCATCTGTGAAATGGAGGGT
AAAATTAAAAATTGGTTAGTATAAAATAAAAATTACCTTAGGAATTTTACTGCTATAATCAACA
CTATGACCAAAAGCAAGTTGGGAAGGAAGGGGATTACTTGACTTACACTTCTATAGCACTGTTA
ATCCAAGAAGGAAGCCAGGATAAGAACTCAAACATAATAGAAGCTGATGTATAGGCCATGGAGG
GGTGCTGCTTACTGACTTGGTGCTCATGGCTTGCTCAGCCTGCTGTCTTACAGAACCCAAGATC
ACCAGTCCAGGAATGGCACCACCCACAATGGGTTGGGTCCTCTCTCATTAATCATTAATTAAGA
AAATGCCCTACAGGCTTGCCTATAGCTGGATCTCATGGAGGCATTTTCTTAATTGAGATTCCTT
CATTTCAGATGACTGTCAAGTTGACAAAATGGCAGTTAGGAAGTCGCTAATGTTTGAAAAGCAC
GAGGCACGTGTCCTGTCTGTAGGCCTCTAGGGGATTGGTGAGTTGGTGTCTTCTGGTCCTCAGG
TACCTGCTATCCTCTCCCCCTTACGACTTACACATAGTCTCTGTTTAGCCTTTTGTAAGTCATT
CTCGAGTTTCAGTAATGAGAAGAAAATGCATGGTAGATTTTATATTGTTTTTAGCAGGA

hide sequence

RefSeq Acc Id:

NM_001399003 ⟹ NP_001385932

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	19,527,746 - 19,536,164 (+)	NCBI
mRatBN7.2	5	14,729,961 - 14,738,379 (+)	NCBI

RefSeq Acc Id:

NM_001399007 ⟹ NP_001385936

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	19,527,746 - 19,536,164 (+)	NCBI
mRatBN7.2	5	14,729,961 - 14,738,379 (+)	NCBI

RefSeq Acc Id:

NM_001399008 ⟹ NP_001385937

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	19,527,746 - 19,536,164 (+)	NCBI
mRatBN7.2	5	14,729,961 - 14,738,379 (+)	NCBI

RefSeq Acc Id:

NM_001399009 ⟹ NP_001385938

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	19,527,746 - 19,536,164 (+)	NCBI
mRatBN7.2	5	14,729,961 - 14,738,379 (+)	NCBI

RefSeq Acc Id:

NR_174148

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	19,527,746 - 19,536,164 (+)	NCBI
mRatBN7.2	5	14,729,961 - 14,738,379 (+)	NCBI

RefSeq Acc Id:

XM_063287273 ⟹ XP_063143343

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	19,527,745 - 19,531,125 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100103	(Get FASTA)	NCBI Sequence Viewer
	NP_001385932	(Get FASTA)	NCBI Sequence Viewer
	NP_001385936	(Get FASTA)	NCBI Sequence Viewer
	NP_001385937	(Get FASTA)	NCBI Sequence Viewer
	NP_001385938	(Get FASTA)	NCBI Sequence Viewer
	XP_063143343	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM11590	(Get FASTA)	NCBI Sequence Viewer
	EDM11591	(Get FASTA)	NCBI Sequence Viewer
	EDM11592	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000074933
	ENSRNOP00000074933.3
	ENSRNOP00000077151
	ENSRNOP00000077151.1
	ENSRNOP00000085368
	ENSRNOP00000085368.1
	ENSRNOP00000098827.1

RefSeq Acc Id:	NP_001100103 ⟸ NM_001106633
- Peptide Label:	isoform 2
- UniProtKB:	D4A4B1 (UniProtKB/TrEMBL), D4A4A7 (UniProtKB/TrEMBL), A6JFJ4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAGMAFGRGTSLDLLRSLPRVSLANLKPSLNSRKRERRPRDRRRGRKCGRGHKGERQRGTRPRL GFEGGQTPFYIRIPKYGFNEGHSFRHQYQPLSLRRLQYLIDLGRVDPTQPIDLTQLVNGRGVTI QPLKRDYGVQLVEEGADTFQAKVNIEVQMASELAIAAIEKNGGVVTTAFYDPRSLGDLMPSSDF HGCQARYSFIHIR hide sequence

Ensembl Acc Id:

ENSRNOP00000011619 ⟸ ENSRNOT00000011619

Ensembl Acc Id:

ENSRNOP00000074933 ⟸ ENSRNOT00000085621

Ensembl Acc Id:

ENSRNOP00000085368 ⟸ ENSRNOT00000117082

Ensembl Acc Id:

ENSRNOP00000077151 ⟸ ENSRNOT00000115029

RefSeq Acc Id:	NP_001385932 ⟸ NM_001399003
- Peptide Label:	isoform 1
- UniProtKB:	A0A8I6A254 (UniProtKB/TrEMBL), A6JFJ5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001385937 ⟸ NM_001399008
- Peptide Label:	isoform 4

RefSeq Acc Id:	NP_001385938 ⟸ NM_001399009
- Peptide Label:	isoform 5
- UniProtKB:	A0A0G2K9B4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001385936 ⟸ NM_001399007
- Peptide Label:	isoform 3

RefSeq Acc Id:	XP_063143343 ⟸ XM_063287273
- Peptide Label:	isoform X1
- UniProtKB:	A6JFJ6 (UniProtKB/TrEMBL), A0A8I5Y9C7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000098827 ⟸ ENSRNOT00000148383

Protein Domains

Large ribosomal subunit protein uL15/eL18

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K9B4-F1-model_v2	AlphaFold	A0A0G2K9B4	1-295	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693544

Promoter ID:

EPDNEW_R4069

Type:

initiation region

Name:

Mrpl15_1

Description:

mitochondrial ribosomal protein L15

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	14,609,710 - 14,609,770	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304796	AgrOrtholog
BioCyc Gene	G2FUF-42151	BioCyc
Ensembl Genes	ENSRNOG00000008566	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000085621	ENTREZGENE
	ENSRNOT00000085621.3	UniProtKB/TrEMBL
	ENSRNOT00000115029	ENTREZGENE
	ENSRNOT00000115029.2	UniProtKB/TrEMBL
	ENSRNOT00000117082	ENTREZGENE
	ENSRNOT00000117082.2	UniProtKB/TrEMBL
	ENSRNOT00000148383.1	UniProtKB/TrEMBL
Gene3D-CATH	3.100.10.10	UniProtKB/TrEMBL
InterPro	L18e/L15P_sf	UniProtKB/TrEMBL
	Ribosomal_L15	UniProtKB/TrEMBL
	Ribosomal_L15_bac-type	UniProtKB/TrEMBL
	Ribosomal_L18e/L15	UniProtKB/TrEMBL
KEGG Report	rno:297799	UniProtKB/TrEMBL
NCBI Gene	297799	ENTREZGENE
PANTHER	39S RIBOSOMAL PROTEIN L15, MITOCHONDRIAL	UniProtKB/TrEMBL
	Ribosom_L15_bac	UniProtKB/TrEMBL
Pfam	Ribosomal_L18e	UniProtKB/TrEMBL
PhenoGen	Mrpl15	PhenoGen
RatGTEx	ENSRNOG00000008566	RatGTEx
Superfamily-SCOP	Ribosomal_L18e/L15	UniProtKB/TrEMBL
UniProt	A0A0G2K9B4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5Y9C7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A254	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0L3T8_RAT	UniProtKB/TrEMBL
	A6JFJ4	ENTREZGENE, UniProtKB/TrEMBL
	A6JFJ5	ENTREZGENE, UniProtKB/TrEMBL
	A6JFJ6	ENTREZGENE, UniProtKB/TrEMBL
	D4A4A7	ENTREZGENE
	D4A4B1	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Mrpl15	mitochondrial ribosomal protein L15	Mrpl15_predicted	mitochondrial ribosomal protein L15 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Mrpl15_predicted	mitochondrial ribosomal protein L15 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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