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Gene: Lmx1a (LIM homeobox transcription factor 1 alpha) Rattus norvegicus

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Symbol:

Lmx1a

Name:

LIM homeobox transcription factor 1 alpha

RGD ID:

1304784

Description:

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in midbrain dopaminergic neuron differentiation; positive regulation of transcription by RNA polymerase II; and synapse organization. Predicted to act upstream of or within several processes, including negative regulation of neuron differentiation; nervous system development; and regulation of cell growth. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 7. Orthologous to human LMX1A (LIM homeobox transcription factor 1 alpha); INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; acrylamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LIM homeobox transcription factor 1-alpha; LOC289201

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LMX1A (LIM homeobox transcription factor 1 alpha)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Lmx1a (LIM homeobox transcription factor 1 alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Lmx1a (LIM homeobox transcription factor 1 alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LMX1A (LIM homeobox transcription factor 1 alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LMX1A (LIM homeobox transcription factor 1 alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Lmx1a (LIM homeobox transcription factor 1 alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LMX1A (LIM homeobox transcription factor 1 alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LMX1A (LIM homeobox transcription factor 1 alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Lmx1a (LIM homeobox transcription factor 1 alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Lmx1a (LIM homeobox transcription factor 1 alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CLASP1 (cytoplasmic linker associated protein 1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	LMX1A (LIM homeobox transcription factor 1 alpha)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Lmx1a (LIM homeobox transcription factor 1 alpha)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	lmx1a (LIM homeobox transcription factor 1, alpha)	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	lim-6	Alliance	DIOPT (Hieranoid\|InParanoid\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	lim-6	Alliance	DIOPT (InParanoid\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG4328	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Lmx1a	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Lmx1a	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	lmx1a	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Is Marker For:

Strains: F344.ACI-Lmx1a^qc/Kyo

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	82,367,493 - 82,511,157 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	82,367,933 - 82,511,154 (+)	Ensembl				GRCr8
mRatBN7.2	13	79,834,614 - 79,978,253 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	79,835,019 - 79,978,253 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	82,464,526 - 82,608,048 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	83,771,877 - 83,915,118 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	81,009,685 - 81,152,976 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	85,916,753 - 86,061,534 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	85,918,252 - 86,061,176 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	90,559,608 - 90,699,381 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	83,354,523 - 83,498,511 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	79,539,405 - 79,680,950 (+)	NCBI		Celera
RGSC_v3.1	13	83,368,247 - 83,511,002 (+)	NCBI
Cytogenetic Map	13	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant nonsyndromic deafness 7 (ISO)

Hearing Loss (ISO)

schizophrenia (ISO)

sensorineural hearing loss (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1-naphthyl isothiocyanate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

alpha-Zearalanol (EXP)

amosite asbestos (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

choline (ISO)

crocidolite asbestos (ISO)

Cuprizon (EXP)

decabromodiphenyl ether (ISO)

diarsenic trioxide (ISO)

dorsomorphin (ISO)

folic acid (ISO)

fulvestrant (ISO)

genistein (EXP)

glycidol (EXP)

L-methionine (ISO)

methylmercury chloride (ISO)

N-acetyl-1,4-benzoquinone imine (ISO)

pentanal (ISO)

perfluorooctanoic acid (EXP)

resveratrol (ISO)

rofecoxib (ISO)

SB 431542 (ISO)

serpentine asbestos (ISO)

simazine (ISO)

sodium arsenite (ISO)

Tetrachlorobisphenol A (ISO)

titanium dioxide (ISO)

triptonide (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axon guidance (ISO)

central nervous system development (ISO)

central nervous system neuron differentiation (IEA,ISO)

cerebellum development (IEA,ISO)

dentate gyrus development (ISO)

dopaminergic neuron differentiation (IEA,ISO)

hippocampus development (ISO)

locomotory behavior (IEA,ISO)

memory (IEA,ISO)

midbrain development (IEA,ISO)

midbrain dopaminergic neuron differentiation (IEA,ISO)

negative regulation of neuron differentiation (ISO)

neuron differentiation (IBA,ISO)

olfactory behavior (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of cell growth (ISO)

regulation of DNA-templated transcription (IEA)

regulation of gene expression (ISO)

regulation of transcription by RNA polymerase II (IBA)

synapse organization (IEA,ISO)

Cellular Component

nucleus (IBA,IEA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA,ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA,IEA)

metal ion binding (IEA)

protein binding (ISO)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IBA,IEA,ISO)

sequence-specific double-stranded DNA binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Mutation at the Lmx1a locus provokes aberrant brain development in the rat.	Kuwamura M, etal., Brain Res Dev Brain Res 2005 Mar 31;155(2):99-106.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:1638738	PMID:15148302	PMID:15183721	PMID:17670789	PMID:19951692	PMID:21752929	PMID:24066094	PMID:25915474

Genomics

Comparative Map Data

Lmx1a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	82,367,493 - 82,511,157 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	82,367,933 - 82,511,154 (+)	Ensembl				GRCr8
mRatBN7.2	13	79,834,614 - 79,978,253 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	79,835,019 - 79,978,253 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	82,464,526 - 82,608,048 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	83,771,877 - 83,915,118 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	81,009,685 - 81,152,976 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	85,916,753 - 86,061,534 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	85,918,252 - 86,061,176 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	90,559,608 - 90,699,381 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	83,354,523 - 83,498,511 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	79,539,405 - 79,680,950 (+)	NCBI		Celera
RGSC_v3.1	13	83,368,247 - 83,511,002 (+)	NCBI
Cytogenetic Map	13	q24	NCBI

LMX1A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	165,201,867 - 165,356,715 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	165,201,867 - 165,356,715 (-)	Ensembl			hg38	GRCh38
GRCh37	1	165,171,104 - 165,325,952 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	163,437,729 - 163,591,641 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	138,276,288 - 138,431,140 (-)	NCBI		Celera
Cytogenetic Map	1	q23.3	NCBI
HuRef	1	136,417,983 - 136,572,723 (-)	NCBI		HuRef
CHM1_1	1	166,593,888 - 166,748,685 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	164,548,251 - 164,703,069 (-)	NCBI		T2T-CHM13v2.0

Lmx1a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	167,515,864 - 167,676,310 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	167,516,806 - 167,676,310 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	167,688,230 - 167,848,741 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	167,689,237 - 167,848,741 (+)	Ensembl			mm10	GRCm38
MGSCv37	1	169,619,689 - 169,778,864 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	169,526,233 - 169,685,408 (+)	NCBI		MGSCv36	mm8
Celera	1	170,119,452 - 170,266,767 (+)	NCBI		Celera
Cytogenetic Map	1	H2.3	NCBI
cM Map	1	75.08	NCBI

Lmx1a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955462	11,329,676 - 11,477,770 (+)	Ensembl
ChiLan1.0	NW_004955462	11,328,583 - 11,484,438 (+)	NCBI	ChiLan1.0	ChiLan1.0

LMX1A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	84,409,236 - 84,566,377 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	84,077,753 - 84,234,862 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	140,634,117 - 140,788,567 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	144,424,654 - 144,579,161 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	144,422,789 - 144,579,027 (-)	Ensembl			panPan2	panpan1.1

LMX1A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	17,958,366 - 18,111,155 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	17,956,961 - 18,109,049 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	18,014,194 - 18,166,310 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	18,038,465 - 18,190,627 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	18,036,655 - 18,190,097 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	18,010,809 - 18,162,874 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	18,362,869 - 18,515,026 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	18,656,952 - 18,809,154 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Lmx1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	102,016,217 - 102,140,149 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936481	19,863,487 - 19,983,926 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936481	19,863,487 - 19,984,299 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LMX1A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	85,406,223 - 85,571,443 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	85,403,287 - 85,570,738 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	93,112,144 - 93,276,353 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LMX1A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	63,533,442 - 63,688,124 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	63,640,244 - 63,686,106 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666055	65,294,865 - 65,449,105 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lmx1a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624826	3,543,191 - 3,689,062 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624826	3,541,291 - 3,689,039 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Lmx1a
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	10	46,996,391 - 47,149,047 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Lmx1a
854 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	252
Count of miRNA genes:	157
Interacting mature miRNAs:	203
Transcripts:	ENSRNOT00000006163
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	48639634	93639634	Rat
10755495	Bp387	Blood pressure QTL 387	3.78		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	37216241	90057603	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	38975045	103588154	Rat
8655951	Rf63	Renal function QTL 63	12.2		blood urea nitrogen amount (VT:0005265)	plasma urea nitrogen level (CMO:0000586)	13	71610804	109350286	Rat
70220	Bp55	Blood pressure QTL 55	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	39924693	84924693	Rat
8655945	Rf61	Renal function QTL 61	3.6		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	13	71610804	89333251	Rat
71119	Thym2	Thymus enlargement QTL 2	3.8		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	13	48749814	87285480	Rat
4889861	Pur29	Proteinuria QTL 29	13.8	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	39968211	83286298	Rat
1331783	Bp221	Blood pressure QTL 221	3.72886		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	71610804	89333251	Rat
8655959	Pur32	Proteinuria QTL 32	8.4		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	72984506	99745408	Rat
1300166	Kidm6	Kidney mass QTL 6	3.93		kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	13	71610804	89333251	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	67635937	109350286	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	7421791	87286911	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
1549897	Stresp12	Stress response QTL 12	3.35		stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	13	40983585	85983585	Rat
724564	Uae11	Urinary albumin excretion QTL 11	5.7		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	13	47354258	94285672	Rat
738027	Lnnr6	Liver neoplastic nodule remodeling QTL 6	3.3		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	65613454	109350286	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
7387280	Uae43	Urinary albumin excretion QTL 43	5.69	0.4174	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	68983334	109350286	Rat
738026	Lnnr5	Liver neoplastic nodule remodeling QTL 5	3.29		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	62424592	88113509	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	67635937	109350286	Rat
61349	Bp31	Blood pressure QTL 31	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	39924693	84924693	Rat
1576318	Schws5	Schwannoma susceptibility QTL 5		0.0351	nervous system integrity trait (VT:0010566)	post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)	13	64497900	109350286	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	11081740	103588154	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
12879477	Bp401	Blood pressure QTL 401			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	39814726	84814726	Rat
1331750	Bp220	Blood pressure QTL 220	2.98		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	39968211	84968211	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	64375743	109350286	Rat
11530006	Niddm72	Non-insulin dependent diabetes mellitus QTL 72		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	38286298	83286298	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	103588154	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	67635937	109350286	Rat

Markers in Region

D13M1Mit110

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	79,901,202 - 79,901,306 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	85,984,895 - 85,984,998	NCBI	Rnor6.0
Rnor_5.0	13	90,623,335 - 90,623,438	UniSTS	Rnor5.0
RGSC_v3.4	13	83,420,933 - 83,421,036	UniSTS	RGSC3.4
Celera	13	79,605,407 - 79,605,510	UniSTS
Cytogenetic Map	13	q24	UniSTS

Related Rat Strains

The following Strains have been annotated to Lmx1a

F344.ACI-Lmx1a^qc/Kyo

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	11	27	143	54	53	22	15	22	6	158	74	10	116	38	64	31	5	5

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001105967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598709	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006163 ⟹ ENSRNOP00000006163

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	82,367,933 - 82,511,154 (+)	Ensembl
mRatBN7.2 Ensembl	13	79,835,019 - 79,978,253 (+)	Ensembl
Rnor_6.0 Ensembl	13	85,918,252 - 86,061,176 (+)	Ensembl

RefSeq Acc Id:

NM_001105967 ⟹ NP_001099437

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	82,367,933 - 82,511,154 (+)	NCBI
mRatBN7.2	13	79,835,019 - 79,978,253 (+)	NCBI
Rnor_6.0	13	85,918,252 - 86,061,176 (+)	NCBI
Rnor_5.0	13	90,559,608 - 90,699,381 (+)	NCBI
RGSC_v3.4	13	83,354,523 - 83,498,511 (+)	RGD
Celera	13	79,539,405 - 79,680,950 (+)	RGD

Sequence:

show sequence

CAGAGCTGTCCGAGCAGTTCGCCGTGGCTCTTCTCTCTCCTCCCACCTCACATTTCCCTTGGCT
GAACTCTACCCTCTAGGCTCATTCTTGTCGCCCTGGACACTCCTGTCCTTCCTCAGGAGAGTGG
CAACTGAGCGTACGGAGTCCCAGCAGGCACGGAAGCTAGACTCAACCATTTCTCCGCTCTGCAG
CTCCTCCTGGCTCAACCCGAACATGTTGGACGGCCTGAAGATGGAAGAGAACTTTCAAAGTGCG
ATTGAGACCTCGGCCTCCTTCTCCTCTTTGCTGGGCAGAGCGGTGAGCCCCAAGTCTGTCTGCG
AGGGCTGTCAGCGGGTCATCTCGGATAGGTTTCTGCTGAGACTCAACGACAGCTTCTGGCACGA
GCAATGCGTGCAGTGCGCCTCTTGCAAAGAGCCCCTGGAGACCACCTGCTTCTACCGGGACAAG
AAGCTCTACTGCAAGTACCACTACGAGAAACTGTTTGCTGTCAAATGTGGGGGCTGCTTCGAAG
CCATTGCGCCCAATGAGTTTGTCATGCGTGCCCAGAAGAGTGTGTACCACCTGAGCTGTTTCTG
CTGCTGTGTCTGCGAGCGACAGCTGCAGAAGGGTGATGAGTTTGTCCTGAAGGAGGGCCAGCTG
CTCTGCAAAGGAGACTATGAGAAGGAGCGAGAGTTGCTGAGCCTGGTGAGCCCAGCAGCCTCAG
ACTCAGGCAAAAGTGATGATGAGGAGAGTCTTTGCAAGTCAGCCCACGGGGCAGGGAAAGGAGC
ATCAGAGGACGGCAAGGACCATAAGCGACCCAAACGTCCCAGAACCATCTTGACCACTCAGCAG
AGGAGAGCATTCAAGGCCTCATTTGAAGTATCCTCCAAGCCCTGCAGAAAGGTGAGGGAGACTC
TGGCTGCGGAGACAGGGCTGAGTGTCCGTGTGGTTCAGGTGTGGTTCCAGAACCAGCGAGCCAA
GATGAAGAAGCTGGCCCGGCGACAGCAGCAACAGCAACAGGATCAACAGAACACCCAGAGGCTG
AGTTCTGCTCAGACAAATGGTAGTGGCAATGCTGGCATGGAAGGCATCATGAACCCCTATACAA
CGTTGCCCACCCCACAGCAACTGCTGGCCATTGAACAGAGCGTCTACAACTCTGATCCCTTCCG
ACAGGGTCTCACCCCACCCCAGATGCCTGGAGATCACATGCACCCCTACGGTGCTGAACCTCTT
TTCCATGACCTGGATAGTGACGACACATCTCTCAGTAACCTGGGCGACTGCTTCCTGGCAACCT
CAGAAGCTGGACCCCTACAGTCCAGAGTGGGAAACCCCATCGACCATCTGTATTCCATGCAGAA
TTCCTATTTCACCTCTTGAGTCTTCTCCTAGAGTGTTGTGGCTGGGCTCCCATGTGGAAGAACC
ATACTGTGTGAGGGATTGCTGACTTTAGGATGGGGAGGCCAGAGAAGAGGTGGGCTGGGGAGGG
AGGTTTGTTGGGGATGCTGTCGTTTAATTATATGGTGTAGCACAGCATTTCCAAAGACTGAATA
CATTATGGATCGCATAGTTTAATGTTTCTAATAAGAATCTTAGTGTTAGATATGAAGATGTGTT
TATCATTAAGGACAGGGTCTTTTAATATAGATATTCTCAAGCAAACTAGATATCTAGGGACTCC
CAACAGCTTCCCGCCATCCCGGAGAAGTGCTTGTCAAGAGGTGCCGTATGTCTATTCATCTACA
CACCAATAGACAGACAGATAGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAAAACCTTTCATA
CTTTATCATCAAAGTTTATTCCTAATTATAACAGACACCAACTGTACAGCAAAAGTAACTTTAT
TTTCAGTGTGAACTATATTTAAGGAAATGCTTGATGCACTTAAGTTATAAAATGAGATAATTTA
CTTTTATAAACTTTATTTTTAGTTGGGAGGGACTCATCGGCAGGGCAGAGAGGGCTACTCCACC
TGGCCCCAAAGCTTTGAGTGCTTGAGTTCGTTCCGTGATCCTAGCCTCATTGAGGGCTAGAATG
TAACGCCCGATGGCAGGCAGCATGCTATAACGAACTCATGCTCACTCTGGTGTCAAGTCACCGG
GCCTGAACGCAATTGTAAGCTTATTGGTATGGTACTGTTGGGTAGCATCTGCAAGGTTGTCTCG
ACCCCCCAGATTCAGCCTCGATGAGTGTGGAAGAAGTTGATAGCCACACCTACCTCCCTCTCTA
TGAGTGTGGATGAGGTGGATGCCACACCTACCTCCCTGGGGACACTAAGGCTCCATACCAGGAC
ATGACTGAGGGTGAAACAAAAATAAATCTGATATGATTTAAAGTATAACTGGATCATGTGCCTG
ATGGTAGAGGATACCTGGGGTCACAGAGCGGGAAGTTCCGGTACCCCAAGTCCTATCTCTCTGC
ACAGCCCACATAGCCACATGACAGAGACACAACTCCGAGGGGGTGGAGACAACACTCCATCTGA
GAAGGTGGGAGAGGCATGGTAGATGGAATTCTAGAGCAAGTGTTGACTTGCACATATGTTTTTT
ATTATTATTTTGTTTTGTTCTTTTTAAAAAGTCGTTTAAAAATGACTGTACGTACCCCAAAATC
CGGAATTACTTGTGATCTCTGTTTGTCTCTTTCTTGAGGGCCCATAGTCTACAGGGCCTGCTCA
TAAACAACCTCATGGAGTTCATAGAAGCAGAGGGGACCAGGCAGGTACCCAGGGCTCTTCCTTT
CATCTCCTTTTGCTGACCCTGAGCACAGGAAGACCCAGCAGCCATTGTACACAGGGACAATTCC
GTGCCCCAATCTCCAATTATGGTGCTAGGATGGGATCTTCTGTGTTAGAATTCTCCGGGGAAGC
AGAATGAGTAGGGGGAAGACAGAAGGACTCCACTGAGAGGGGCTGTGACAGGCATGCCTGGGGA
CGTCATCAGAGCCACGAACATGCCCACCTATCCACGTCATTCTCTGCAAGGCCAGAGGAAGCAT
GTCCCTTAGTCGTAGAGTGTGTGTTGTGTGATTTTTGTGCTCTTCTTTATAATTTATACAAACC
ATCGGGAAACCCGAACCAGTCTGTTGACTGAGAATGAGGCAGGCACAGGTGGCACGGACGGTGT
CTGTGTGGCTGATTGGTTGGAGAATGTAGCAGATATTATGTGAATGAAAGCAAACAGAGATCCT
TAATTCTACTCTCTAATGATATACCGAGATGAAATTAAAAGCCTCTTACGAA

hide sequence

RefSeq Acc Id:

XM_017598709 ⟹ XP_017454198

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	82,367,493 - 82,511,157 (+)	NCBI
mRatBN7.2	13	79,834,614 - 79,978,247 (+)	NCBI
Rnor_6.0	13	85,916,753 - 86,061,534 (+)	NCBI

Sequence:

show sequence

TTCAAGGTTTGGCCGTGGGTCCTATTATTGCATTTCCCAGCAGTGAAGTGGTTTCGGTCAGAAA
CGTCTAGGTGGCACGGATCTCGGCCGAGGCTGGGGCGCAGCTCCCCCGGGGACAACCGTTCCAC
GTGGAGAGGAGGAAAAGTTTGGCGCGTCCGGGAGGTCCAGGCAGCAGACCGGAGCATCAGGCTG
CAGCCTCGCGGTGGGTCGAGCAGCCAAGCAGGGAAACCGAGCACCGCGGGCCCCGCCACGGGAC
GCGCTCCCAGGCCCCCGCCCTGCGCACCCCACCCCCTTCCCGGGCCGCGCACGCAGCCAGCGGC
CGCTGTCAGAAACGGCCGGAGCCGCCTCGGAGAAGAAAGCAGGGCGGACTTTGCACCCAGGACC
CTGGGTCTCGGGTTTCCCCTCCGATCTTGGAACAGCCGCCTGGCTTCCCCTTCCCGGTCGCAGA
AAGGCGCGGGTTGGCGGGACGTCCCAAGAAAGATCTGCGGCTTGCGGCCACGGCCCGGCCCGAC
TCCGGCGCGTCTAGGAGCAGAACCCGGGGCCAGCGGTCGCTCCTGCTCTCTCCCGGGCGCGCCG
GAGTCCGGGCGGCTGCTCGGGCTGCAGCCTCGGGAACGCCACCTCCCTCTGCCGAAGCTGCCCG
GAGCCTCCCGGGCACTTCGTGCCGCTCCCGACGCCGGGAGCGAGCTCGCCCATCAGACGTTCCC
AGCACTGGCCGACCAGCGGGAGGACCTCCCTGCGCGCCCCGCACGCCTACTCCCGCGTGCCCCC
CCACCCCCCAGCAGAGCGCAGCGCCAGGAGTACGGAAGCAGGCGGGACGGTCTCCCTGTCCCTT
ACTCTGCCTCTCTCCAACCCAAGACAGGCTCATTCTTGTCGCCCTGGACACTCCTGTCCTTCCT
CAGGAGAGTGGCAACTGAGCGTACGGAGTCCCAGCAGGCACGGAAGCTAGACTCAACCATTTCT
CCGCTCTGCAGCTCCTCCTGGCTCAACCCGAACATGTTGGACGGCCTGAAGATGGAAGAGAACT
TTCAAAGTGCGATTGAGACCTCGGCCTCCTTCTCCTCTTTGCTGGGCAGAGCGGTGAGCCCCAA
GTCTGTCTGCGAGGGCTGTCAGCGGGTCATCTCGGATAGGTTTCTGCTGAGACTCAACGACAGC
TTCTGGCACGAGCAATGCGTGCAGTGCGCCTCTTGCAAAGAGCCCCTGGAGACCACCTGCTTCT
ACCGGGACAAGAAGCTCTACTGCAAGTACCACTACGAGAAACTGTTTGCTGTCAAATGTGGGGG
CTGCTTCGAAGCCATTGCGCCCAATGAGTTTGTCATGCGTGCCCAGAAGAGTGTGTACCACCTG
AGCTGTTTCTGCTGCTGTGTCTGCGAGCGACAGCTGCAGAAGGGTGATGAGTTTGTCCTGAAGG
AGGGCCAGCTGCTCTGCAAAGGAGACTATGAGAAGGAGCGAGAGTTGCTGAGCCTGGTGAGCCC
AGCAGCCTCAGACTCAGGCAAAAGTGATGATGAGGAGAGTCTTTGCAAGTCAGCCCACGGGGCA
GGGAAAGGAGCATCAGAGGACGGCAAGGACCATAAGCGACCCAAACGTCCCAGAACCATCTTGA
CCACTCAGCAGAGGAGAGCATTCAAGGCCTCATTTGAAGTATCCTCCAAGCCCTGCAGAAAGGT
GAGGGAGACTCTGGCTGCGGAGACAGGGCTGAGTGTCCGTGTGGTTCAGGTGTGGTTCCAGAAC
CAGCGAGCCAAGATGAAGAAGCTGGCCCGGCGACAGCAGCAACAGCAACAGGATCAACAGAACA
CCCAGAGGCTGAGTTCTGCTCAGACAAATGGTAGTGGCAATGCTGGCATGGAAGGCATCATGAA
CCCCTATACAACGTTGCCCACCCCACAGCAACTGCTGGCCATTGAACAGAGCGTCTACAACTCT
GATCCCTTCCGACAGGGTCTCACCCCACCCCAGATGCCTGGAGATCACATGCACCCCTACGGTG
CTGAACCTCTTTTCCATGACCTGGATAGTGACGACACATCTCTCAGTAACCTGGGCGACTGCTT
CCTGGCAACCTCAGAAGCTGGACCCCTACAGTCCAGAGTGGGAAACCCCATCGACCATCTGTAT
TCCATGCAGAATTCCTATTTCACCTCTTGAGTCTTCTCCTAGAGTGTTGTGGCTGGGCTCCCAT
GTGGAAGAACCATACTGTGTGAGGGATTGCTGACTTTAGGATGGGGAGGCCAGAGAAGAGGTGG
GCTGGGGAGGGAGGTTTGTTGGGGATGCTGTCGTTTAATTATATGGTGTAGCACAGCATTTCCA
AAGACTGAATACATTATGGATCGCATAGTTTAATGTTTCTAATAAGAATCTTAGTGTTAGATAT
GAAGATGTGTTTATCATTAAGGACAGGGTCTTTTAATATAGATATTCTCAAGCAAACTAGATAT
CTAGGGACTCCCAACAGCTTCCCGCCATCCCGGAGAAGTGCTTGTCAAGAGGTGCCGTATGTCT
ATTCATCTACACACCAATAGACAGACAGATAGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAA
AACCTTTCATACTTTATCATCAAAGTTTATTCCTAATTATAACAGACACCAACTGTACAGCAAA
AGTAACTTTATTTTCAGTGTGAACTATATTTAAGGAAATGCTTGATGCACTTAAGTTATAAAAT
GAGATAATTTACTTTTATAAACTTTATTTTTAGTTGGGAGGGACTCATCGGCAGGGCAGAGAGG
GCTACTCCACCTGGCCCCAAAGCTTTGAGTGCTTGAGTTCGTTCCGTGATCCTAGCCTCATTGA
GGGCTAGAATGTAACGCCCGATGGCAGGCAGCATGCTATAACGAACTCATGCTCACTCTGGTGT
CAAGTCACCGGGCCTGAACGCAATTGTAAGCTTATTGGTATGGTACTGTTGGGTAGCATCTGCA
AGGTTGTCTCGACCCCCCAGATTCAGCCTCGATGAGTGTGGAAGAAGTTGATAGCCACACCTAC
CTCCCTCTCTATGAGTGTGGATGAGGTGGATGCCACACCTACCTCCCTGGGGACACTAAGGCTC
CATACCAGGACATGACTGAGGGTGAAACAAAAATAAATCTGATATGATTTAAAGTATAACTGGA
TCATGTGCCTGATGGTAGAGGATACCTGGGGTCACAGAGCGGGAAGTTCCGGTACCCCAAGTCC
TATCTCTCTGCACAGCCCACATAGCCACATGACAGAGACACAACTCCGAGGGGGTGGAGACAAC
ACTCCATCTGAGAAGGTGGGAGAGGCATGGTAGATGGAATTCTAGAGCAAGTGTTGACTTGCAC
ATATGTTTTTTATTATTATTTTGTTTTGTTCTTTTTAAAAAGTCGTTTAAAAATGACTGTACGT
ACCCCAAAATCCGGAATTACTTGTGATCTCTGTTTGTCTCTTTCTTGAGGGCCCATAGTCTACA
GGGCCTGCTCATAAACAACCTCATGGAGTTCATAGAAGCAGAGGGGACCAGGCAGGTACCCAGG
GCTCTTCCTTTCATCTCCTTTTGCTGACCCTGAGCACAGGAAGACCCAGCAGCCATTGTACACA
GGGACAATTCCGTGCCCCAATCTCCAATTATGGTGCTAGGATGGGATCTTCTGTGTTAGAATTC
TCCGGGGAAGCAGAATGAGTAGGGGGAAGACAGAAGGACTCCACTGAGAGGGGCTGTGACAGGC
ATGCCTGGGGACGTCATCAGAGCCACGAACATGCCCACCTATCCACGTCATTCTCTGCAAGGCC
AGAGGAAGCATGTCCCTTAGTCGTAGAGTGTGTGTTGTGTGATTTTTGTGCTCTTCTTTATAAT
TTATACAAACCATCGGGAAACCCGAACCAGTCTGTTGACTGAGAATGAGGCAGGCACAGGTGGC
ACGGACGGTGTCTGTGTGGCTGATTGGTTGGAGAATGTAGCAGATATTATGTGAATGAAAGCAA
ACAGAGATCCTTAATTCTACTCTCTAATGATATACCGAGATGAAATTAAAAGCCTCTTACGAAT
GAGCCATTGTTTATTTGGGGGAGTATGGTGGGCAGGGAACGGGGAGAGGAAGGGGGACATGGGA
GTTTCTTCCATGGAGATGTGAGTTTCTTCTGCAGAGGCATGGGGATGTGCTTGTGGTGAAACTT
CAAGCCTAAAGGGAAGGGAAGCCTCTAGCTAAGACGGATAAGGTCCTAAAGCCGCCCCTCTTCC
TCCGAGAGGTTCTGGAATGTTCCGTCCTTGCTGTAGAGGTCTCTCACGACAGAGGTTGCAGCGC
ACAGTGTGTGCCCTTAGCTTTGGCTCATCATGGGGGCCAGCTGAAGAAGCAGTATTTCTCCTGT
AGGGCTTGACACAAATGCCTGACAGAATGGGAGAGCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001099437	(Get FASTA)	NCBI Sequence Viewer
	XP_017454198	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM09278	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006163
	ENSRNOP00000006163.4

RefSeq Acc Id:

NP_001099437 ⟸ NM_001105967

- UniProtKB:

F1LRJ8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLDGLKMEENFQSAIETSASFSSLLGRAVSPKSVCEGCQRVISDRFLLRLNDSFWHEQCVQCAS
CKEPLETTCFYRDKKLYCKYHYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQ
LQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGASEDGKDH
KRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARR
QQQQQQDQQNTQRLSSAQTNGSGNAGMEGIMNPYTTLPTPQQLLAIEQSVYNSDPFRQGLTPPQ
MPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGPLQSRVGNPIDHLYSMQNSYFTS

hide sequence

RefSeq Acc Id:	XP_017454198 ⟸ XM_017598709
- Peptide Label:	isoform X1
- UniProtKB:	F1LRJ8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLDGLKMEENFQSAIETSASFSSLLGRAVSPKSVCEGCQRVISDRFLLRLNDSFWHEQCVQCAS CKEPLETTCFYRDKKLYCKYHYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQ LQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGASEDGKDH KRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARR QQQQQQDQQNTQRLSSAQTNGSGNAGMEGIMNPYTTLPTPQQLLAIEQSVYNSDPFRQGLTPPQ MPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGPLQSRVGNPIDHLYSMQNSYFTS hide sequence

Ensembl Acc Id:

ENSRNOP00000006163 ⟸ ENSRNOT00000006163

Protein Domains

Homeobox LIM zinc-binding

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LRJ8-F1-model_v2	AlphaFold	F1LRJ8	1-382	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304784	AgrOrtholog
BioCyc Gene	G2FUF-17504	BioCyc
Ensembl Genes	ENSRNOG00000004642	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006163	ENTREZGENE
	ENSRNOT00000006163.7	UniProtKB/TrEMBL
Gene3D-CATH	Cysteine Rich Protein	UniProtKB/TrEMBL
	Homeodomain-like	UniProtKB/TrEMBL
InterPro	Homeobox	UniProtKB/TrEMBL
	Homeobox_CS	UniProtKB/TrEMBL
	Homeodomain-like	UniProtKB/TrEMBL
	LIM_Homeobox_TF	UniProtKB/TrEMBL
	Lmx1a_LIM1	UniProtKB/TrEMBL
	Znf_LIM	UniProtKB/TrEMBL
KEGG Report	rno:289201	UniProtKB/TrEMBL
NCBI Gene	289201	ENTREZGENE
PANTHER	LIM HOMEOBOX TRANSCRIPTION FACTOR 1-ALPHA	UniProtKB/TrEMBL
	LIM/HOMEOBOX PROTEIN LHX	UniProtKB/TrEMBL
Pfam	Homeobox	UniProtKB/TrEMBL
	LIM	UniProtKB/TrEMBL
PhenoGen	Lmx1a	PhenoGen
PROSITE	HOMEOBOX_1	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
	LIM_DOMAIN_1	UniProtKB/TrEMBL
	LIM_DOMAIN_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000004642	RatGTEx
SMART	HOX	UniProtKB/TrEMBL
	LIM	UniProtKB/TrEMBL
Superfamily-SCOP	Glucocorticoid receptor-like (DNA-binding domain)	UniProtKB/TrEMBL
	Homeodomain_like	UniProtKB/TrEMBL
UniProt	F1LRJ8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Lmx1a	LIM homeobox transcription factor 1 alpha	Lmx1a_predicted	LIM homeobox transcription factor 1 alpha (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Lmx1a_predicted	LIM homeobox transcription factor 1 alpha (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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