Arhgef19 (Rho guanine nucleotide exchange factor 19) - Rat Genome Database

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Gene: Arhgef19 (Rho guanine nucleotide exchange factor 19) Rattus norvegicus
Analyze
Symbol: Arhgef19
Name: Rho guanine nucleotide exchange factor 19
RGD ID: 1304766
Description: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of actin cytoskeleton organization and wound healing. Predicted to act upstream of or within positive regulation of GTPase activity. Orthologous to human ARHGEF19 (Rho guanine nucleotide exchange factor 19); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC362648; Rho guanine nucleotide exchange factor (GEF) 19
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,818,840 - 158,837,196 (+)NCBIGRCr8
mRatBN7.25153,536,038 - 153,554,203 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,536,013 - 153,554,203 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5156,225,060 - 156,243,226 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05157,998,343 - 158,016,509 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05157,987,537 - 158,005,703 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05159,754,954 - 159,773,699 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,755,535 - 159,773,699 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05163,471,143 - 163,494,854 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45160,091,794 - 160,109,955 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15160,105,466 - 160,120,135 (+)NCBI
Celera5151,900,596 - 151,919,574 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
alpha-Zearalanol  (EXP)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
CGP 52608  (ISO)
chlorohydrocarbon  (EXP)
cisplatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
Cuprizon  (EXP)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenthion  (ISO)
fentin chloride  (EXP)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
leflunomide  (EXP)
medroxyprogesterone acetate  (ISO)
methidathion  (ISO)
methylmercury chloride  (EXP)
N-nitrosodiethylamine  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
paracetamol  (ISO)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
sinapic acid  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triptonide  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
XL147  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:20643356  


Genomics

Comparative Map Data
Arhgef19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,818,840 - 158,837,196 (+)NCBIGRCr8
mRatBN7.25153,536,038 - 153,554,203 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,536,013 - 153,554,203 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5156,225,060 - 156,243,226 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05157,998,343 - 158,016,509 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05157,987,537 - 158,005,703 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05159,754,954 - 159,773,699 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,755,535 - 159,773,699 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05163,471,143 - 163,494,854 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45160,091,794 - 160,109,955 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15160,105,466 - 160,120,135 (+)NCBI
Celera5151,900,596 - 151,919,574 (+)NCBICelera
Cytogenetic Map5q36NCBI
ARHGEF19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38116,197,854 - 16,212,652 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl116,197,854 - 16,212,652 (-)EnsemblGRCh38hg38GRCh38
GRCh37116,524,349 - 16,539,147 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36116,397,186 - 16,411,691 (-)NCBINCBI36Build 36hg18NCBI36
Build 34116,269,904 - 16,284,410NCBI
Celera115,004,527 - 15,018,992 (-)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef115,042,069 - 15,056,569 (-)NCBIHuRef
CHM1_1116,323,212 - 16,337,699 (-)NCBICHM1_1
T2T-CHM13v2.0115,639,202 - 15,653,982 (-)NCBIT2T-CHM13v2.0
Arhgef19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394140,966,916 - 140,985,226 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4140,966,810 - 140,984,875 (+)EnsemblGRCm39 Ensembl
GRCm384141,239,605 - 141,257,915 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,239,499 - 141,257,564 (+)EnsemblGRCm38mm10GRCm38
MGSCv374140,798,799 - 140,813,477 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364140,514,960 - 140,529,638 (+)NCBIMGSCv36mm8
Celera4143,051,066 - 143,065,764 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map473.53NCBI
Arhgef19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555272,077,806 - 2,088,880 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555272,073,009 - 2,087,291 (+)NCBIChiLan1.0ChiLan1.0
ARHGEF19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21210,704,388 - 210,723,902 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11209,957,569 - 209,972,560 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0115,334,564 - 15,354,061 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1116,327,135 - 16,342,004 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl116,327,135 - 16,342,009 (-)Ensemblpanpan1.1panPan2
ARHGEF19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,484,068 - 81,499,961 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,486,146 - 81,499,584 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,016,450 - 78,036,107 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0282,126,388 - 82,146,073 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl282,132,250 - 82,146,085 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,879,368 - 78,899,043 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0279,896,590 - 79,916,272 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0280,964,447 - 80,984,130 (+)NCBIUU_Cfam_GSD_1.0
Arhgef19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505837,881,800 - 37,897,803 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364743,706,100 - 3,719,641 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364743,706,584 - 3,716,010 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGEF19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,317,823 - 75,335,270 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1675,317,811 - 75,335,292 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2669,633,523 - 69,650,991 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGEF19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120116,088,130 - 116,107,499 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20116,096,423 - 116,107,884 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605419,583,206 - 19,602,766 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgef19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247642,325,151 - 2,348,631 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247642,325,151 - 2,339,161 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arhgef19
84 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:425
Count of miRNA genes:240
Interacting mature miRNAs:273
Transcripts:ENSRNOT00000036739, ENSRNOT00000067574
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5151113452164465185Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5151006154161165494Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat

Markers in Region
RH132654  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25153,553,483 - 153,553,702 (+)MAPPERmRatBN7.2
Rnor_6.05159,772,980 - 159,773,198NCBIRnor6.0
Rnor_5.05163,494,135 - 163,494,353UniSTSRnor5.0
Celera5151,918,855 - 151,919,073UniSTS
RH 3.4 Map51052.4UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 9 49 113 91 90 59 24 59 6 215 95 93 45 58 31

Sequence


Ensembl Acc Id: ENSRNOT00000067574   ⟹   ENSRNOP00000061876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5153,536,038 - 153,554,203 (+)Ensembl
Rnor_6.0 Ensembl5159,755,535 - 159,773,699 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096539   ⟹   ENSRNOP00000093983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5153,536,013 - 153,554,203 (+)Ensembl
RefSeq Acc Id: NM_001108692   ⟹   NP_001102162
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,819,032 - 158,837,196 (+)NCBI
mRatBN7.25153,536,038 - 153,554,203 (+)NCBI
Rnor_6.05159,755,535 - 159,773,699 (+)NCBI
Rnor_5.05163,471,143 - 163,494,854 (+)NCBI
RGSC_v3.45160,091,794 - 160,109,955 (+)RGD
Celera5151,900,596 - 151,919,574 (+)RGD
Sequence:
RefSeq Acc Id: XM_008764270   ⟹   XP_008762492
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,818,840 - 158,837,139 (+)NCBI
mRatBN7.25153,536,167 - 153,554,146 (+)NCBI
Rnor_6.05159,754,954 - 159,773,642 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008764272   ⟹   XP_008762494
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,822,158 - 158,837,139 (+)NCBI
mRatBN7.25153,539,175 - 153,554,146 (+)NCBI
Rnor_6.05159,757,802 - 159,773,642 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593525   ⟹   XP_017449014
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,824,876 - 158,837,139 (+)NCBI
mRatBN7.25153,542,043 - 153,554,146 (+)NCBI
Rnor_6.05159,761,312 - 159,773,642 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039110425   ⟹   XP_038966353
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,824,628 - 158,837,139 (+)NCBI
mRatBN7.25153,541,658 - 153,554,146 (+)NCBI
RefSeq Acc Id: NP_001102162   ⟸   NM_001108692
- UniProtKB: D4A646 (UniProtKB/TrEMBL),   A6ITS3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762492   ⟸   XM_008764270
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ALI5 (UniProtKB/TrEMBL),   A6ITS4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762494   ⟸   XM_008764272
- Peptide Label: isoform X2
- UniProtKB: A6ITS5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449014   ⟸   XM_017593525
- Peptide Label: isoform X2
- UniProtKB: A6ITS5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000061876   ⟸   ENSRNOT00000067574
RefSeq Acc Id: XP_038966353   ⟸   XM_039110425
- Peptide Label: isoform X2
- UniProtKB: A6ITS5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000093983   ⟸   ENSRNOT00000096539
Protein Domains
DH   PH   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A646-F1-model_v2 AlphaFold D4A646 1-888 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694222
Promoter ID:EPDNEW_R4747
Type:initiation region
Name:Arhgef19_1
Description:Rho guanine nucleotide exchange factor 19
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05159,755,576 - 159,755,636EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304766 AgrOrtholog
BioCyc Gene G2FUF-39355 BioCyc
Ensembl Genes ENSRNOG00000047967 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067574.4 UniProtKB/TrEMBL
  ENSRNOT00000096539.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.900.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro DBL_dom_sf UniProtKB/TrEMBL
  DH-domain UniProtKB/TrEMBL
  Ephexin-like UniProtKB/TrEMBL
  PH/PTB_dom UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PH_ephexin UniProtKB/TrEMBL
  SH3-like_dom UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
KEGG Report rno:362648 UniProtKB/TrEMBL
NCBI Gene 362648 ENTREZGENE
PANTHER GUANINE NUCLEOTIDE EXCHANGE FACTOR UniProtKB/TrEMBL
  RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 19 UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
  SH3_2 UniProtKB/TrEMBL
PhenoGen Arhgef19 PhenoGen
PROSITE DH_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047967 RatGTEx
SMART RhoGEF UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP DH-domain UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt A0A8I6ALI5 ENTREZGENE, UniProtKB/TrEMBL
  A6ITS3 ENTREZGENE, UniProtKB/TrEMBL
  A6ITS4 ENTREZGENE, UniProtKB/TrEMBL
  A6ITS5 ENTREZGENE, UniProtKB/TrEMBL
  D4A646 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-19 Arhgef19  Rho guanine nucleotide exchange factor 19  Arhgef19  Rho guanine nucleotide exchange factor (GEF) 19  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Arhgef19  Rho guanine nucleotide exchange factor (GEF) 19   Arhgef19_predicted  Rho guanine nucleotide exchange factor (GEF) 19 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Arhgef19_predicted  Rho guanine nucleotide exchange factor (GEF) 19 (predicted)      Symbol and Name status set to approved 70820 APPROVED