Message Center
{{ messageCount }} Messages
Watched Genes
{{$index + 1}}. {{ watchedObject.symbol }} (RGD ID:{{watchedObject.rgdId}})
Watched Ontology Terms
{{$index + 1}}. {{ watchedTerm.term }} ({{watchedTerm.accId}})
{{gene.symbol}}: {{ gene.description }}
You must be logged in to use this feature
{{ loginError }}
Select categories you would like to watch. Updates to this gene will be sent to {{ username }}
x
Send Message
Gene: Ppp2r1b (protein phosphatase 2 scaffold subunit A beta) Rattus norvegicus
Analyze
Symbol:
Ppp2r1b
Name:
protein phosphatase 2 scaffold subunit A beta
RGD ID:
1304764
Description:
Predicted to enable protein phosphatase regulator activity. Predicted to be involved in several processes, including meiotic sister chromatid cohesion, centromeric; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; and spindle assembly. Predicted to be located in membrane raft. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytosol; glutamatergic synapse; and nucleus. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human PPP2R1B (protein phosphatase 2 scaffold subunit Abeta); PARTICIPATES IN phosphatidylinositol 3-kinase-Akt signaling pathway; Chagas disease pathway; hepatitis C pathway; INTERACTS WITH 1,3-dinitrobenzene; 6-propyl-2-thiouracil; amitrole.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
LOC315648; PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta; PP2A, subunit A, PR65-beta isoform; PP2A, subunit A, R1-beta isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform; protein phosphatase 2, regulatory subunit A, beta; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
PPP2R1B (protein phosphatase 2 scaffold subunit Abeta) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):
Ppp2r1b (protein phosphatase 2, regulatory subunit A, beta) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Ppp2r1b (protein phosphatase 2 scaffold subunit Abeta) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
PPP2R1B (protein phosphatase 2 scaffold subunit Abeta) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
PPP2R1B (protein phosphatase 2 scaffold subunit Abeta) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Ppp2r1b (protein phosphatase 2 scaffold subunit Abeta) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
PPP2R1B (protein phosphatase 2 scaffold subunit Abeta) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
PPP2R1B (protein phosphatase 2 scaffold subunit Abeta) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Ppp2r1b (protein phosphatase 2 scaffold subunit Abeta) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Ppp2r1b (protein phosphatase 2 scaffold subunit Abeta) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
PPP2R1A (protein phosphatase 2 scaffold subunit Aalpha) HGNC
OrthoDB
Homo sapiens (human):
CPEB3 (cytoplasmic polyadenylation element binding protein 3) HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
PPP2R1B (protein phosphatase 2 scaffold subunit Abeta)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Ppp2r1b (protein phosphatase 2, regulatory subunit A, beta)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
paa-1
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
paa-1
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
Pp2A-29B
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
Pp2A-29B
Alliance
DIOPT (Ensembl Compara|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
TPD3
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
ppp2r1ba
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Danio rerio (zebrafish):
ppp2r1bb
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
ppp2r1bb
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
ppp2r1b
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
ppp2r1b
Alliance
DIOPT (OMA|OrthoFinder)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 8 60,092,540 - 60,125,512 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 8 60,081,553 - 60,125,795 (+) Ensembl GRCr8 mRatBN7.2 8 51,195,860 - 51,228,442 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 8 51,186,717 - 51,228,485 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 8 56,700,526 - 56,721,504 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 8 54,979,460 - 55,000,438 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 8 52,843,710 - 52,864,688 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 8 55,279,278 - 55,311,768 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 8 55,279,373 - 55,301,320 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 8 53,865,408 - 53,907,521 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 8 54,208,126 - 54,229,044 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 8 50,743,113 - 50,764,139 (+) NCBI Celera RGSC_v3.1 8 54,227,179 - 54,248,096 (+) NCBI Cytogenetic Map 8 q23 NCBI
JBrowse:
Imported Disease Annotations - ClinVar
Imported Disease Annotations - CTD
Imported Disease Annotations - OMIM
Only show annotations with direct experimental evidence (0 objects hidden)
Ppp2r1b Rat (1->4)-beta-D-glucan multiple interactions ISO Ppp2r1b (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PPP2R1B mRNA CTD PMID:36331819 Ppp2r1b Rat 1,10-phenanthroline decreases expression ISO PPP2R1B (Homo sapiens) 6480464 1,10-phenanthroline results in decreased expression of PPP2R1B mRNA CTD PMID:19502547 Ppp2r1b Rat 1,2-dichloroethane increases expression ISO Ppp2r1b (Mus musculus) 6480464 ethylene dichloride results in increased expression of PPP2R1B mRNA CTD PMID:28960355 Ppp2r1b Rat 1,3-dinitrobenzene decreases expression EXP 6480464 3-dinitrobenzene results in decreased expression of PPP2R1B mRNA CTD PMID:22841810 Ppp2r1b Rat 1-chloro-2,4-dinitrobenzene affects binding ISO PPP2R1B (Homo sapiens) 6480464 Dinitrochlorobenzene binds to PPP2R1B protein CTD PMID:32991956 Ppp2r1b Rat 17beta-estradiol increases expression ISO Ppp2r1b (Mus musculus) 6480464 Estradiol results in increased expression of PPP2R1B mRNA; Estradiol results in increased expression of PPP2R1B more ... CTD PMID:26903627|PMID:39298647 Ppp2r1b Rat 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO PPP2R1B (Homo sapiens) 6480464 2,2',4,4'-tetrabromodiphenyl ether analog results in decreased expression of PPP2R1B mRNA; 2,2',4,4'-tetrabromodiphenyl ether results in decreased more ... CTD PMID:19095052|PMID:31675489 Ppp2r1b Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ppp2r1b (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of PPP2R1B mRNA CTD PMID:21570461 Ppp2r1b Rat 2,4,6-tribromophenol decreases expression ISO PPP2R1B (Homo sapiens) 6480464 2,4,6-tribromophenol results in decreased expression of PPP2R1B mRNA CTD PMID:31675489 Ppp2r1b Rat 3,3',5,5'-tetrabromobisphenol A decreases expression ISO PPP2R1B (Homo sapiens) 6480464 tetrabromobisphenol A results in decreased expression of PPP2R1B protein CTD PMID:31675489 Ppp2r1b Rat 3,4-methylenedioxymethamphetamine decreases expression ISO Ppp2r1b (Mus musculus) 6480464 N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of PPP2R1B mRNA CTD PMID:26251327 Ppp2r1b Rat 4,4'-sulfonyldiphenol increases expression ISO PPP2R1B (Homo sapiens) 6480464 bisphenol S results in increased expression of PPP2R1B mRNA CTD PMID:27685785 Ppp2r1b Rat 4,4'-sulfonyldiphenol decreases expression ISO Ppp2r1b (Mus musculus) 6480464 bisphenol S results in decreased expression of PPP2R1B mRNA CTD PMID:39298647 Ppp2r1b Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of PPP2R1B mRNA CTD PMID:30047161 Ppp2r1b Rat 7,12-dimethyltetraphene decreases expression ISO PPP2R1B (Homo sapiens) 6480464 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of PPP2R1B mRNA CTD PMID:19502547 Ppp2r1b Rat acrylamide increases expression ISO Ppp2r1b (Mus musculus) 6480464 Acrylamide results in increased expression of PPP2R1B mRNA CTD PMID:30807115 Ppp2r1b Rat aflatoxin B1 decreases expression ISO PPP2R1B (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of PPP2R1B mRNA CTD PMID:22100608 Ppp2r1b Rat aflatoxin B1 decreases methylation ISO PPP2R1B (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of PPP2R1B gene CTD PMID:27153756 Ppp2r1b Rat all-trans-retinoic acid decreases expression ISO PPP2R1B (Homo sapiens) 6480464 Tretinoin results in decreased expression of PPP2R1B mRNA CTD PMID:15498508 Ppp2r1b Rat amitrole increases expression EXP 6480464 Amitrole results in increased expression of PPP2R1B mRNA CTD PMID:30047161 Ppp2r1b Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PPP2R1B mRNA CTD PMID:25181051 Ppp2r1b Rat bisphenol A decreases expression ISO PPP2R1B (Homo sapiens) 6480464 bisphenol A results in decreased expression of PPP2R1B protein CTD PMID:37567409 Ppp2r1b Rat bisphenol A decreases methylation ISO PPP2R1B (Homo sapiens) 6480464 bisphenol A results in decreased methylation of PPP2R1B gene CTD PMID:31601247 Ppp2r1b Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PPP2R1B mRNA CTD PMID:34947998 Ppp2r1b Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of PPP2R1B gene CTD PMID:28505145 Ppp2r1b Rat bisphenol A increases expression ISO PPP2R1B (Homo sapiens) 6480464 bisphenol A results in increased expression of PPP2R1B mRNA CTD PMID:27685785 Ppp2r1b Rat bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of PPP2R1B mRNA CTD PMID:32479839 Ppp2r1b Rat C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of PPP2R1B mRNA CTD PMID:19167457 Ppp2r1b Rat cadmium atom decreases expression ISO PPP2R1B (Homo sapiens) 6480464 Cadmium results in decreased expression of PPP2R1B mRNA CTD PMID:23369406 Ppp2r1b Rat cadmium atom multiple interactions ISO Ppp2r1b (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PPP2R1B more ... CTD PMID:37236586 Ppp2r1b Rat cadmium atom increases expression ISO PPP2R1B (Homo sapiens) 6480464 Cadmium results in increased expression of PPP2R1B mRNA CTD PMID:31463135 Ppp2r1b Rat cadmium dichloride multiple interactions ISO PPP2R1B (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPP2R1B protein] CTD PMID:18703135 Ppp2r1b Rat cadmium dichloride multiple interactions ISO Ppp2r1b (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PPP2R1B more ... CTD PMID:37236586 Ppp2r1b Rat cadmium dichloride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPP2R1B protein] CTD PMID:18703135 Ppp2r1b Rat cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of PPP2R1B mRNA; Cadmium Chloride results in decreased expression more ... CTD PMID:18703135|PMID:33453195 Ppp2r1b Rat cadmium dichloride decreases expression ISO PPP2R1B (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of PPP2R1B protein CTD PMID:18703135 Ppp2r1b Rat carbamazepine affects expression ISO PPP2R1B (Homo sapiens) 6480464 Carbamazepine affects the expression of PPP2R1B mRNA CTD PMID:24752500 Ppp2r1b Rat carbon nanotube increases expression ISO Ppp2r1b (Mus musculus) 6480464 Nanotubes, Carbon results in increased expression of PPP2R1B mRNA CTD PMID:25620056 Ppp2r1b Rat CGP 52608 multiple interactions ISO PPP2R1B (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to PPP2R1B gene] CTD PMID:28238834 Ppp2r1b Rat cobalt(2+) sulfate decreases expression ISO PPP2R1B (Homo sapiens) 6480464 cobalt sulfate results in decreased expression of PPP2R1B mRNA CTD PMID:19502547 Ppp2r1b Rat copper atom multiple interactions ISO PPP2R1B (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in decreased expression of PPP2R1B mRNA CTD PMID:30911355 Ppp2r1b Rat copper(0) multiple interactions ISO PPP2R1B (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in decreased expression of PPP2R1B mRNA CTD PMID:30911355 Ppp2r1b Rat copper(II) sulfate decreases expression ISO PPP2R1B (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of PPP2R1B mRNA CTD PMID:19549813 Ppp2r1b Rat cyclosporin A decreases expression ISO PPP2R1B (Homo sapiens) 6480464 Cyclosporine results in decreased expression of PPP2R1B mRNA CTD PMID:27989131 Ppp2r1b Rat decabromodiphenyl ether decreases expression ISO PPP2R1B (Homo sapiens) 6480464 decabromobiphenyl ether results in decreased expression of PPP2R1B protein CTD PMID:31675489 Ppp2r1b Rat diclofenac affects expression ISO PPP2R1B (Homo sapiens) 6480464 Diclofenac affects the expression of PPP2R1B mRNA CTD PMID:24752500 Ppp2r1b Rat dicrotophos decreases expression ISO PPP2R1B (Homo sapiens) 6480464 dicrotophos results in decreased expression of PPP2R1B mRNA CTD PMID:28302478 Ppp2r1b Rat dorsomorphin multiple interactions ISO PPP2R1B (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Ppp2r1b Rat epoxiconazole increases expression ISO Ppp2r1b (Mus musculus) 6480464 epoxiconazole results in increased expression of PPP2R1B mRNA CTD PMID:35436446 Ppp2r1b Rat ethanol affects expression ISO Ppp2r1b (Mus musculus) 6480464 Ethanol affects the expression of PPP2R1B mRNA CTD PMID:30319688 Ppp2r1b Rat finasteride increases expression EXP 6480464 Finasteride results in increased expression of PPP2R1B mRNA CTD PMID:24136188 Ppp2r1b Rat fipronil decreases expression EXP 6480464 fipronil results in decreased expression of PPP2R1B mRNA CTD PMID:34044035 Ppp2r1b Rat flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of PPP2R1B mRNA CTD PMID:24793618 Ppp2r1b Rat formaldehyde decreases expression ISO PPP2R1B (Homo sapiens) 6480464 Formaldehyde results in decreased expression of PPP2R1B mRNA CTD PMID:23649840 Ppp2r1b Rat glyphosate decreases expression ISO PPP2R1B (Homo sapiens) 6480464 Glyphosate results in decreased expression of PPP2R1B mRNA CTD PMID:31295307 Ppp2r1b Rat GSK-J4 decreases expression ISO PPP2R1B (Homo sapiens) 6480464 GSK-J4 results in decreased expression of PPP2R1B mRNA CTD PMID:29301935 Ppp2r1b Rat hydralazine multiple interactions ISO PPP2R1B (Homo sapiens) 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of PPP2R1B mRNA CTD PMID:17183730 Ppp2r1b Rat ivermectin decreases expression ISO PPP2R1B (Homo sapiens) 6480464 Ivermectin results in decreased expression of PPP2R1B protein CTD PMID:32959892 Ppp2r1b Rat methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of PPP2R1B mRNA CTD PMID:22484513 Ppp2r1b Rat methimazole increases expression EXP 6480464 Methimazole results in increased expression of PPP2R1B mRNA CTD PMID:30047161 Ppp2r1b Rat N-acetyl-L-cysteine multiple interactions ISO PPP2R1B (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPP2R1B protein] CTD PMID:18703135 Ppp2r1b Rat N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPP2R1B protein] CTD PMID:18703135 Ppp2r1b Rat nickel sulfate increases expression ISO PPP2R1B (Homo sapiens) 6480464 nickel sulfate results in increased expression of PPP2R1B mRNA CTD PMID:16780908 Ppp2r1b Rat niclosamide multiple interactions ISO PPP2R1B (Homo sapiens) 6480464 Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of PPP2R1B mRNA] CTD PMID:27542212 Ppp2r1b Rat obeticholic acid increases expression ISO PPP2R1B (Homo sapiens) 6480464 obeticholic acid results in increased expression of PPP2R1B mRNA CTD PMID:27939613 Ppp2r1b Rat ochratoxin A decreases expression ISO PPP2R1B (Homo sapiens) 6480464 ochratoxin A results in decreased expression of PPP2R1B mRNA CTD PMID:19287073 Ppp2r1b Rat okadaic acid decreases expression ISO PPP2R1B (Homo sapiens) 6480464 Okadaic Acid results in decreased expression of PPP2R1B mRNA CTD PMID:38832940 Ppp2r1b Rat PCB138 increases expression EXP 6480464 2,2',3',4,4',5-hexachlorobiphenyl results in increased expression of PPP2R1B protein CTD PMID:21673325 Ppp2r1b Rat pentachlorophenol increases expression ISO Ppp2r1b (Mus musculus) 6480464 Pentachlorophenol results in increased expression of PPP2R1B mRNA CTD PMID:23892564 Ppp2r1b Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Ppp2r1b (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PPP2R1B mRNA CTD PMID:36331819 Ppp2r1b Rat pirinixic acid increases expression ISO Ppp2r1b (Mus musculus) 6480464 pirinixic acid results in increased expression of PPP2R1B mRNA CTD PMID:18301758 Ppp2r1b Rat piroxicam decreases expression ISO PPP2R1B (Homo sapiens) 6480464 Piroxicam results in decreased expression of PPP2R1B mRNA CTD PMID:21858171 Ppp2r1b Rat propiconazole increases expression EXP 6480464 propiconazole results in increased expression of PPP2R1B mRNA CTD PMID:30047161 Ppp2r1b Rat Propiverine affects binding EXP 6480464 propiverine binds to PPP2R1B protein CTD PMID:29273565 Ppp2r1b Rat pyrvinium multiple interactions ISO PPP2R1B (Homo sapiens) 6480464 pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of PPP2R1B mRNA] CTD PMID:27542212 Ppp2r1b Rat quercetin decreases expression ISO PPP2R1B (Homo sapiens) 6480464 Quercetin results in decreased expression of PPP2R1B mRNA CTD PMID:21632981 Ppp2r1b Rat riddelliine multiple interactions ISO PPP2R1B (Homo sapiens) 6480464 [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PPP2R1B more ... CTD PMID:33884520 Ppp2r1b Rat rotenone increases expression EXP 6480464 Rotenone results in increased expression of PPP2R1B mRNA CTD PMID:28374803 Ppp2r1b Rat SB 431542 multiple interactions ISO PPP2R1B (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Ppp2r1b Rat silicon dioxide increases expression ISO PPP2R1B (Homo sapiens) 6480464 Silicon Dioxide results in increased expression of PPP2R1B mRNA CTD PMID:25351596 Ppp2r1b Rat sirolimus multiple interactions ISO PPP2R1B (Homo sapiens) 6480464 Sirolimus inhibits the reaction [PIK3CA protein modified form results in increased expression of PPP2R1B mRNA] CTD PMID:27542212 Ppp2r1b Rat sodium arsenite decreases expression ISO PPP2R1B (Homo sapiens) 6480464 sodium arsenite results in decreased expression of PPP2R1B mRNA; sodium arsenite results in decreased expression more ... CTD PMID:38228842|PMID:38568856 Ppp2r1b Rat sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of PPP2R1B mRNA CTD PMID:25993096 Ppp2r1b Rat sulfadimethoxine increases expression EXP 6480464 Sulfadimethoxine results in increased expression of PPP2R1B mRNA CTD PMID:30047161 Ppp2r1b Rat tamibarotene affects expression ISO PPP2R1B (Homo sapiens) 6480464 tamibarotene affects the expression of PPP2R1B mRNA CTD PMID:15498508 Ppp2r1b Rat testosterone decreases expression ISO PPP2R1B (Homo sapiens) 6480464 Testosterone results in decreased expression of PPP2R1B mRNA CTD PMID:33359661 Ppp2r1b Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of PPP2R1B mRNA CTD PMID:23411599|PMID:34492290 Ppp2r1b Rat thiram decreases expression ISO PPP2R1B (Homo sapiens) 6480464 Thiram results in decreased expression of PPP2R1B mRNA CTD PMID:38568856 Ppp2r1b Rat trichostatin A increases expression ISO PPP2R1B (Homo sapiens) 6480464 trichostatin A results in increased expression of PPP2R1B mRNA CTD PMID:26272509 Ppp2r1b Rat trichostatin A multiple interactions ISO PPP2R1B (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Ppp2r1b Rat triphenyl phosphate affects expression ISO PPP2R1B (Homo sapiens) 6480464 triphenyl phosphate affects the expression of PPP2R1B mRNA CTD PMID:37042841 Ppp2r1b Rat triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of PPP2R1B mRNA CTD PMID:30589522 Ppp2r1b Rat triptonide increases expression ISO Ppp2r1b (Mus musculus) 6480464 triptonide results in increased expression of PPP2R1B mRNA CTD PMID:33045310 Ppp2r1b Rat valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of PPP2R1B mRNA CTD PMID:24136188 Ppp2r1b Rat valproic acid multiple interactions ISO PPP2R1B (Homo sapiens) 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of PPP2R1B mRNA; [NOG protein co-treated more ... CTD PMID:17183730|PMID:27188386 Ppp2r1b Rat valproic acid increases expression ISO PPP2R1B (Homo sapiens) 6480464 Valproic Acid results in increased expression of PPP2R1B mRNA CTD PMID:23179753|PMID:26272509 Ppp2r1b Rat valproic acid affects expression ISO PPP2R1B (Homo sapiens) 6480464 Valproic Acid affects the expression of PPP2R1B mRNA CTD PMID:25979313 Ppp2r1b Rat vitamin E decreases expression ISO PPP2R1B (Homo sapiens) 6480464 Vitamin E results in decreased expression of PPP2R1B mRNA CTD PMID:19244175 Ppp2r1b Rat zinc sulfate affects expression ISO PPP2R1B (Homo sapiens) 6480464 Zinc Sulfate affects the expression of PPP2R1B protein CTD PMID:25162517
Molecular Function
Only show annotations with direct experimental evidence (0 objects hidden)
Ppp2r1b Rat protein binding enables ISO RGD:1312396,UniProtKB:P30154-2 1624291 UniProtKB:O14901|UniProtKB:O75190-2 PMID:32814053 RGD PMID:32814053 Ppp2r1b Rat protein binding enables ISO PPP2R1B (Homo sapiens) 1624291 UniProtKB:O08722|UniProtKB:O08785|UniProtKB:P11233|UniProtKB:P30153|UniProtKB:P63151|UniProtKB:P67775|UniProtKB:Q13362|UniProtKB:Q14738|UniProtKB:Q15172|UniProtKB:Q16537 PMID:16456541, PMID:17540176, PMID:18715871, PMID:18782753, PMID:19156129, PMID:21172653, PMID:23555304, PMID:26496610, PMID:28330616, PMID:33961781, PMID:35271311, PMID:40205054, PMID:8392071 RGD PMID:16456541|PMID:17540176|PMID:18715871|PMID:18782753|PMID:19156129|PMID:21172653|PMID:23555304|PMID:26496610|PMID:28330616|PMID:33961781|PMID:35271311|PMID:40205054|PMID:8392071 Ppp2r1b Rat protein binding enables ISO RGD:1552002,MGI:1920949 1624291 UniProtKB:Q8K1S3 PMID:21172653 RGD PMID:21172653 Ppp2r1b Rat protein phosphatase regulator activity enables IBA FB:FBgn0260439|PANTHER:PTN000068596|UniProtKB:P30153|WB:WBGene00008878 1600115 GO_REF:0000033 GO_Central GO_REF:0000033
Imported Annotations - KEGG (archival)
QTLs in Region (GRCr8)
1298065 Scl16 Serum cholesterol level QTL 16 3.8 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 8 39752803 84752803 Rat 2313057 Bss76 Bone structure and strength QTL 76 3 0.0001 tibia size trait (VT:0100001) tibia midshaft cross-sectional area (CMO:0001717) 8 39106258 91341052 Rat 1549908 Neudeg1 Neurodegradation QTL 1 5.5 0 nervous system integrity trait (VT:0010566) logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986) 8 58337123 103337123 Rat 2317030 Wbc5 White blood cell count QTL 5 3.21 0.005 leukocyte quantity (VT:0000217) white blood cell count (CMO:0000027) 8 16994642 61994642 Rat 1554321 Bmd3 Bone mineral density QTL 3 7.9 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 8 49849908 118871671 Rat 2313067 Bss77 Bone structure and strength QTL 77 3.1 0.0001 tibia size trait (VT:0100001) tibia midshaft endosteal cross-sectional area (CMO:0001716) 8 39106258 91341052 Rat 1578769 Uae31 Urinary albumin excretion QTL 31 3.3 0.001 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 8 39106363 103375781 Rat 2301416 Bp315 Blood pressure QTL 315 0.008 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 8 15952279 60952279 Rat 1298079 Activ2 Activity QTL 2 9.5 0.000001 voluntary movement trait (VT:0003491) rearing measurement (CMO:0001515) 8 50763951 95763951 Rat 11556286 Cm81 Cardiac mass QTL 81 0.01 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 8 39106258 84106258 Rat 70161 Bp62 Blood pressure QTL 62 2.9 0.001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 8 51589699 99045312 Rat 1578765 Klgr1 Kidney lesion grade QTL 1 3.3 0.0001 kidney morphology trait (VT:0002135) organ lesion measurement (CMO:0000677) 8 39106363 103375781 Rat 61464 Niddm11 Non-insulin dependent diabetes mellitus QTL 11 3.1 0.001 blood insulin amount (VT:0001560) plasma insulin level (CMO:0000342) 8 44477926 89477926 Rat 2317051 Aia18 Adjuvant induced arthritis QTL 18 2.42 joint integrity trait (VT:0010548) left rear ankle joint diameter (CMO:0002149) 8 16994642 61994642 Rat 4889938 Bss89 Bone structure and strength QTL 89 3.8 tibia size trait (VT:0100001) tibia cortical bone volume (CMO:0001725) 8 58991697 91341052 Rat 1578755 Pur5 Proteinuria QTL 5 3.3 0.0001 urine total protein amount (VT:0000032) urine total protein excretion rate (CMO:0000756) 8 39106258 103375958 Rat 2313086 Bss60 Bone structure and strength QTL 60 4.1 0.0001 tibia length (VT:0004357) tibia length (CMO:0000450) 8 58991697 91341052 Rat 2313088 Bss75 Bone structure and strength QTL 75 3.1 0.0001 body length (VT:0001256) body length, nose to rump (CMO:0000079) 8 39106258 91341052 Rat 1358896 Bp262 Blood pressure QTL 262 2.89 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 8 35464071 107982864 Rat 731182 Uae24 Urinary albumin excretion QTL 24 6.4 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 8 47541419 92541419 Rat 724514 Uae15 Urinary albumin excretion QTL 15 2.9 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 8 37760859 61459705 Rat 631648 Stl5 Serum triglyceride level QTL 5 4 0.0003 blood triglyceride amount (VT:0002644) plasma triglyceride level (CMO:0000548) 8 35464071 71842899 Rat 1331837 Bw23 Body weight QTL 23 4.19 0.00007 body mass (VT:0001259) body weight (CMO:0000012) 8 55428416 107963099 Rat 61353 Bp35 Blood pressure QTL 35 0.001 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 8 39106258 84106258 Rat 737824 Hcar10 Hepatocarcinoma resistance QTL 10 2.9 liver integrity trait (VT:0010547) liver tumorous lesion number (CMO:0001068) 8 49610204 68373388 Rat 631842 Inf1 Infertility severity QTL 1 4.1 0.001 seminal gland mass (VT:0010524) seminal vesicle wet weight (CMO:0001603) 8 31543661 76543661 Rat 1331769 Rf39 Renal function QTL 39 3.871 urine output (VT:0003620) timed urine volume (CMO:0000260) 8 50763951 107970527 Rat 1359033 Bp273 Blood pressure QTL 273 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 8 39106258 84106258 Rat 1358906 Bp253 Blood pressure QTL 253 4 0.0004 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 8 49610204 94610204 Rat 61358 Bp39 Blood pressure QTL 39 2 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 8 44447837 89447837 Rat 1358907 Cm40 Cardiac mass QTL 40 1.89 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 8 35464071 107982864 Rat 1598824 Memor4 Memory QTL 4 2.5 exploratory behavior trait (VT:0010471) total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443) 8 17993862 62252873 Rat 70197 BpQTLcluster8 Blood pressure QTL cluster 8 3.482 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 8 55428333 127966348 Rat 1331744 Bp217 Blood pressure QTL 217 3.398 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 8 39106258 67378345 Rat 2316950 Scl66 Serum cholesterol level QTL 66 4.1 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 8 39106363 114525825 Rat 2313046 Bss78 Bone structure and strength QTL 78 3.5 0.0001 tibia strength trait (VT:1000284) tibia total energy absorbed before break (CMO:0001736) 8 39106258 91341052 Rat 1582254 Kidm31 Kidney mass QTL 31 3 kidney mass (VT:0002707) both kidneys wet weight (CMO:0000085) 8 49245178 94245178 Rat 724540 Uae8 Urinary albumin excretion QTL 8 5 urine albumin amount (VT:0002871) urine albumin level (CMO:0000130) 8 39106258 103375958 Rat 1358892 Kidm26 Kidney mass QTL 26 3.69 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 8 35464071 107982864 Rat 631216 Stl9 Serum triglyceride level QTL 9 4.71 0.0001 blood triglyceride amount (VT:0002644) serum triglyceride level (CMO:0000360) 8 50763951 67219641 Rat 1582243 Bw66 Body weight QTL 66 3.4 0.0048 body mass (VT:0001259) body weight (CMO:0000012) 8 49245178 94245178 Rat 5684973 Bss100 Bone structure and strength QTL 100 4.7 tibia area (VT:1000281) tibia area measurement (CMO:0001382) 8 58991697 91341052 Rat 61373 Mcs4 Mammary carcinoma susceptibility QTL 4 1.1 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 8 44475043 89475043 Rat
