Ca8 (carbonic anhydrase 8) - Rat Genome Database

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Gene: Ca8 (carbonic anhydrase 8) Rattus norvegicus
Analyze
Symbol: Ca8 (Ensembl: Car8)
Name: carbonic anhydrase 8
RGD ID: 1304709
Description: Predicted to enable carbonate dehydratase activity and zinc ion binding activity. Predicted to act upstream of or within positive regulation of calcium-mediated signaling. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 34. Orthologous to human CA8 (carbonic anhydrase 8); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CA-VIII; Car8; carbonic anhydrase VIII; carbonic anhydrase-related protein; CARP; LOC297814; MGC105764
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8526,102,767 - 26,199,819 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl526,102,813 - 26,199,796 (-)EnsemblGRCr8
mRatBN7.2521,302,940 - 21,402,395 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl521,305,383 - 21,402,374 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx523,538,258 - 23,635,134 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0525,125,409 - 25,222,414 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0524,905,671 - 25,002,676 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0521,249,018 - 21,345,810 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl521,249,020 - 21,345,810 (-)Ensemblrn6Rnor6.0
Rnor_5.0526,010,374 - 26,106,856 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4521,951,255 - 22,049,427 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera520,578,323 - 20,675,389 (-)NCBICelera
RGSC_v3.1521,951,256 - 22,049,427 (-)NCBI
Cytogenetic Map5q13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-Zearalanol  (EXP)
Ampullosporin  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (EXP)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
carbon nanotube  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
diazinon  (EXP)
dibenz[a,h]anthracene  (ISO)
diethyl phthalate  (EXP,ISO)
diethylstilbestrol  (EXP)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
ethylparaben  (ISO)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
genistein  (EXP,ISO)
glafenine  (EXP)
hydralazine  (ISO)
inulin  (ISO)
ketamine  (EXP)
lead diacetate  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (EXP)
manganese(0)  (EXP)
manganese(II) chloride  (EXP)
medroxyprogesterone acetate  (ISO)
monoethyl phthalate  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
okadaic acid  (ISO)
oxaliplatin  (EXP)
panobinostat  (ISO)
paracetamol  (ISO)
PCB138  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
pyrogallol  (ISO)
quercetin  (EXP)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
troglitazone  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:12611586   PMID:15489334  


Genomics

Comparative Map Data
Ca8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8526,102,767 - 26,199,819 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl526,102,813 - 26,199,796 (-)EnsemblGRCr8
mRatBN7.2521,302,940 - 21,402,395 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl521,305,383 - 21,402,374 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx523,538,258 - 23,635,134 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0525,125,409 - 25,222,414 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0524,905,671 - 25,002,676 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0521,249,018 - 21,345,810 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl521,249,020 - 21,345,810 (-)Ensemblrn6Rnor6.0
Rnor_5.0526,010,374 - 26,106,856 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4521,951,255 - 22,049,427 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera520,578,323 - 20,675,389 (-)NCBICelera
RGSC_v3.1521,951,256 - 22,049,427 (-)NCBI
Cytogenetic Map5q13NCBI
CA8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38860,185,412 - 60,281,400 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl860,185,412 - 60,281,573 (-)Ensemblhg38GRCh38
GRCh37861,097,971 - 61,193,959 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36861,263,977 - 61,356,508 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34861,263,976 - 61,356,508NCBI
Celera857,092,480 - 57,182,989 (-)NCBICelera
Cytogenetic Map8q12.1NCBI
HuRef856,589,359 - 56,681,767 (-)NCBIHuRef
CHM1_1861,153,453 - 61,246,009 (-)NCBICHM1_1
T2T-CHM13v2.0860,609,460 - 60,705,474 (-)NCBIT2T-CHM13v2.0
Car8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3948,141,491 - 8,239,226 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl48,143,362 - 8,239,041 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3848,141,493 - 8,239,041 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl48,143,362 - 8,239,041 (-)Ensemblmm10GRCm38
MGSCv3748,068,640 - 8,166,188 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3647,613,848 - 7,709,581 (-)NCBIMGSCv36mm8
MGSCv3648,068,640 - 8,166,188 (-)NCBIMGSCv36mm8
Celera48,024,484 - 8,115,866 (-)NCBICelera
Cytogenetic Map4A1NCBI
cM Map43.53NCBI
Ca8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544418,413,958 - 18,512,213 (+)Ensembl
ChiLan1.0NW_00495544418,414,006 - 18,510,800 (+)NCBIChiLan1.0ChiLan1.0
CA8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2775,849,731 - 75,945,025 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1851,502,683 - 51,597,675 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0856,606,454 - 56,702,357 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1858,273,696 - 58,367,615 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl858,273,696 - 58,367,615 (-)EnsemblpanPan2panpan1.1
CA8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12910,678,122 - 10,763,361 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2910,679,038 - 10,764,193 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2910,989,287 - 11,075,445 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02910,763,585 - 10,849,785 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2910,785,281 - 10,850,629 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12910,765,703 - 10,851,540 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02910,899,217 - 10,985,514 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02911,167,585 - 11,253,944 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ca8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530361,800,602 - 61,889,623 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649612,895,888 - 12,984,303 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649612,895,858 - 12,984,303 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl473,047,847 - 73,141,989 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1473,047,867 - 73,172,215 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2479,510,120 - 79,573,391 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CA8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1856,111,149 - 56,203,797 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl856,131,599 - 56,203,336 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603985,472,882 - 85,568,158 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ca8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474431,658,539 - 31,748,022 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474431,659,318 - 31,777,409 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Ca8
716 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:353
Count of miRNA genes:208
Interacting mature miRNAs:234
Transcripts:ENSRNOT00000007802
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)51373115343590997Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5862723052665523Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51460607859606078Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51757663362576633Rat
1578774Tcas8Tongue tumor susceptibility QTL 83.47tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)51570745160707451Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
2312562Pur18Proteinuria QTL 182.60.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)5692228237468560Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51748608062486080Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2303577Gluco47Glucose level QTL 473blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51652001961520019Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)51748608062486080Rat
2313085Bss59Bone structure and strength QTL 592.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)5862723053627230Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat

Markers in Region
D5Got135  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8526,187,299 - 26,187,486 (+)Marker Load Pipeline
mRatBN7.2521,389,876 - 21,390,062 (+)MAPPERmRatBN7.2
Rnor_6.0521,333,315 - 21,333,500NCBIRnor6.0
Rnor_5.0526,094,361 - 26,094,546UniSTSRnor5.0
RGSC_v3.4522,036,932 - 22,037,117UniSTSRGSC3.4
RGSC_v3.4522,036,930 - 22,037,117RGDRGSC3.4
Celera520,662,894 - 20,663,079UniSTS
RGSC_v3.1522,036,930 - 22,037,117RGD
RH 3.4 Map5110.2RGD
RH 3.4 Map5110.2UniSTS
RH 2.0 Map5115.0RGD
Cytogenetic Map5q13UniSTS
AA923902  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8526,102,963 - 26,103,143 (+)Marker Load Pipeline
mRatBN7.2521,305,533 - 21,305,713 (+)MAPPERmRatBN7.2
Rnor_6.0521,249,173 - 21,249,352NCBIRnor6.0
Rnor_5.0526,010,529 - 26,010,708UniSTSRnor5.0
RGSC_v3.4521,951,410 - 21,951,589UniSTSRGSC3.4
Celera520,578,478 - 20,578,657UniSTS
RH 3.4 Map5107.3UniSTS
Cytogenetic Map5q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 76 59 6 340 176 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000007802   ⟹   ENSRNOP00000007802
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl526,102,813 - 26,199,796 (-)Ensembl
mRatBN7.2 Ensembl521,305,383 - 21,402,374 (-)Ensembl
Rnor_6.0 Ensembl521,249,020 - 21,345,810 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081296   ⟹   ENSRNOP00000074141
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl526,102,813 - 26,158,136 (-)Ensembl
mRatBN7.2 Ensembl521,305,383 - 21,360,666 (-)Ensembl
Rnor_6.0 Ensembl521,282,625 - 21,345,805 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106574   ⟹   ENSRNOP00000077757
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl526,102,813 - 26,158,290 (-)Ensembl
mRatBN7.2 Ensembl521,305,383 - 21,358,270 (-)Ensembl
RefSeq Acc Id: NM_001009662   ⟹   NP_001009662
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8526,102,809 - 26,199,796 (-)NCBI
mRatBN7.2521,305,379 - 21,402,374 (-)NCBI
Rnor_6.0521,249,018 - 21,345,810 (-)NCBI
Rnor_5.0526,010,374 - 26,106,856 (-)NCBI
RGSC_v3.4521,951,255 - 22,049,427 (-)RGD
Celera520,578,323 - 20,675,389 (-)RGD
Sequence:
RefSeq Acc Id: XM_039109403   ⟹   XP_038965331
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8526,150,679 - 26,199,819 (-)NCBI
mRatBN7.2521,353,318 - 21,402,395 (-)NCBI
RefSeq Acc Id: XM_039109404   ⟹   XP_038965332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8526,102,767 - 26,155,452 (-)NCBI
mRatBN7.2521,302,940 - 21,358,026 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001009662 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965331 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965332 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87586 (Get FASTA)   NCBI Sequence Viewer  
  EDM11644 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000007802
  ENSRNOP00000007802.5
  ENSRNOP00000074141
GenBank Protein Q5PPN4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001009662   ⟸   NM_001009662
- UniProtKB: Q5PPN4 (UniProtKB/Swiss-Prot),   A6JFP9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000007802   ⟸   ENSRNOT00000007802
Ensembl Acc Id: ENSRNOP00000074141   ⟸   ENSRNOT00000081296
RefSeq Acc Id: XP_038965332   ⟸   XM_039109404
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y6A0 (UniProtKB/TrEMBL),   A0A0G2K7B9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965331   ⟸   XM_039109403
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000077757   ⟸   ENSRNOT00000106574
Protein Domains
Alpha-carbonic anhydrase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5PPN4-F1-model_v2 AlphaFold Q5PPN4 1-290 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693555
Promoter ID:EPDNEW_R4080
Type:single initiation site
Name:Car8_1
Description:carbonic anhydrase 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0521,345,818 - 21,345,878EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304709 AgrOrtholog
BioCyc Gene G2FUF-42063 BioCyc
Ensembl Genes ENSRNOG00000005669 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000007802 ENTREZGENE
  ENSRNOT00000007802.8 UniProtKB/Swiss-Prot
  ENSRNOT00000081296 ENTREZGENE
Gene3D-CATH 3.10.200.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7318288 IMAGE-MGC_LOAD
InterPro CA_dom UniProtKB/Swiss-Prot
  CA_dom_sf UniProtKB/Swiss-Prot
  Carbonic_anhydrase_a-class UniProtKB/Swiss-Prot
  Carbonic_anhydrase_a-class_CS UniProtKB/Swiss-Prot
  CARP_VIII UniProtKB/Swiss-Prot
KEGG Report rno:297814 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105764 IMAGE-MGC_LOAD
NCBI Gene 297814 ENTREZGENE
PANTHER CARBONIC ANHYDRASE-RELATED PROTEIN UniProtKB/Swiss-Prot
  PTHR18952 UniProtKB/Swiss-Prot
Pfam Carb_anhydrase UniProtKB/Swiss-Prot
PhenoGen Ca8 PhenoGen
PROSITE ALPHA_CA_1 UniProtKB/Swiss-Prot
  ALPHA_CA_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000005669 RatGTEx
SMART Carb_anhydrase UniProtKB/Swiss-Prot
Superfamily-SCOP SSF51069 UniProtKB/Swiss-Prot
UniProt A0A0G2K7B9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y6A0 ENTREZGENE, UniProtKB/TrEMBL
  A6JFP9 ENTREZGENE, UniProtKB/TrEMBL
  CAH8_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-04-28 Ca8  carbonic anhydrase 8  Car8  carbonic anhydrase 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2022-04-18 Car8  carbonic anhydrase 8  Ca8  carbonic anhydrase 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2019-04-16 Ca8  carbonic anhydrase 8  Car8  carbonic anhydrase 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Car8  carbonic anhydrase 8  Car8_predicted  carbonic anhydrase 8 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Car8_predicted  carbonic anhydrase 8 (predicted)      Symbol and Name status set to approved 70820 APPROVED