Alkbh8 (alkB homolog 8, tRNA methyltransferase) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Alkbh8 (alkB homolog 8, tRNA methyltransferase) Rattus norvegicus
Analyze
Symbol: Alkbh8
Name: alkB homolog 8, tRNA methyltransferase
RGD ID: 1304687
Description: Predicted to enable tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity; tRNA binding activity; and transition metal ion binding activity. Predicted to be involved in DNA damage response; tRNA methylation; and tRNA wobble uridine modification. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 71. Orthologous to human ALKBH8 (alkB homolog 8, tRNA methyltransferase); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: alkB, alkylation repair homolog 8; alkB, alkylation repair homolog 8 (E. coli); alkylated DNA repair protein alkB homolog 8; LOC366783; RGD1304687; similar to CG17807-PA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr866,121,402 - 6,198,226 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl66,124,253 - 6,198,080 (-)EnsemblGRCr8
mRatBN7.26378,779 - 449,382 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6378,100 - 452,165 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6595,173 - 665,789 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06904,464 - 975,082 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06428,856 - 499,473 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0618,877,885 - 18,952,773 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl618,877,907 - 18,949,393 (+)Ensemblrn6Rnor6.0
Rnor_5.0628,775,065 - 28,848,187 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47306,104 - 378,289 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6201,982 - 272,550 (-)NCBICelera
RGSC_v3.17303,328 - 364,955 (+)NCBI
Cytogenetic Map6q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA,ISO)
cytosol  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA,IEA,ISO)
tRNA methyltransferase complex  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16778019   PMID:20123966   PMID:20308323   PMID:20583019   PMID:21285950   PMID:22065580   PMID:31079898  


Genomics

Comparative Map Data
Alkbh8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr866,121,402 - 6,198,226 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl66,124,253 - 6,198,080 (-)EnsemblGRCr8
mRatBN7.26378,779 - 449,382 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6378,100 - 452,165 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6595,173 - 665,789 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06904,464 - 975,082 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06428,856 - 499,473 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0618,877,885 - 18,952,773 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl618,877,907 - 18,949,393 (+)Ensemblrn6Rnor6.0
Rnor_5.0628,775,065 - 28,848,187 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47306,104 - 378,289 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6201,982 - 272,550 (-)NCBICelera
RGSC_v3.17303,328 - 364,955 (+)NCBI
Cytogenetic Map6q11NCBI
ALKBH8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811107,502,727 - 107,565,735 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11107,502,727 - 107,565,742 (-)Ensemblhg38GRCh38
GRCh3711107,373,453 - 107,436,461 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611106,880,541 - 106,941,637 (-)NCBIBuild 36Build 36hg18NCBI36
Celera11104,528,270 - 104,591,267 (-)NCBICelera
Cytogenetic Map11q22.3NCBI
HuRef11103,298,990 - 103,361,859 (-)NCBIHuRef
CHM1_111107,256,482 - 107,319,496 (-)NCBICHM1_1
T2T-CHM13v2.011107,509,865 - 107,572,838 (-)NCBIT2T-CHM13v2.0
Alkbh8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3993,335,151 - 3,391,154 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl93,335,140 - 3,391,154 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3893,335,231 - 3,391,154 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl93,335,140 - 3,391,154 (+)Ensemblmm10GRCm38
MGSCv3793,335,231 - 3,385,847 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3693,335,231 - 3,385,847 (+)NCBIMGSCv36mm8
Celera3119,303,969 - 119,354,371 (-)NCBICelera
Cytogenetic Map9A1NCBI
cM Map92.02NCBI
Alkbh8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554129,875,905 - 9,923,728 (-)NCBIChiLan1.0ChiLan1.0
ALKBH8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29108,248,602 - 108,314,314 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111109,342,635 - 109,408,238 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011102,390,687 - 102,456,357 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111105,872,588 - 105,937,472 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11105,872,588 - 105,937,472 (-)EnsemblpanPan2panpan1.1
ALKBH8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1524,843,145 - 24,897,906 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl524,833,373 - 25,080,451 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha524,735,966 - 24,816,371 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0524,846,405 - 24,927,699 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl524,872,170 - 24,927,311 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1524,898,995 - 24,979,807 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0524,787,338 - 24,866,870 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0524,849,452 - 24,928,244 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Alkbh8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494790,412,791 - 90,466,041 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365511,076,117 - 1,123,877 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365511,070,484 - 1,123,427 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALKBH8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl936,077,192 - 36,119,920 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1936,077,004 - 36,119,936 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2940,124,426 - 40,167,572 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ALKBH8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1198,929,404 - 98,996,932 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl198,931,375 - 98,991,732 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604326,950,739 - 27,017,650 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Alkbh8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247842,255,492 - 2,373,824 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Alkbh8
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v17228,925 - 327,548 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Alkbh8
476 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:47
Count of miRNA genes:44
Interacting mature miRNAs:46
Transcripts:ENSRNOT00000003432
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6197587946975879Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6197587946975879Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6144788383Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6197587946975879Rat
2293706Bmd20Bone mineral density QTL 204.30.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)6125740059Rat
2292616Ept15Estrogen-induced pituitary tumorigenesis QTL 154.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6197587946975879Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6323998948239989Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6323998948239989Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6140163351Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6120510098Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6323998948239989Rat
1358190Ept1Estrogen-induced pituitary tumorigenesis QTL 14.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6323998948239989Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6197587946975879Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 354 192 11 144 79 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001191909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ741949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000003432   ⟹   ENSRNOP00000003432
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl618,880,737 - 18,949,393 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084222   ⟹   ENSRNOP00000072411
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl66,124,253 - 6,195,387 (-)Ensembl
mRatBN7.2 Ensembl6378,100 - 452,165 (-)Ensembl
Rnor_6.0 Ensembl618,877,907 - 18,949,119 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000131743   ⟹   ENSRNOP00000112389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl66,124,782 - 6,195,387 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000143570   ⟹   ENSRNOP00000100756
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl66,124,782 - 6,198,080 (-)Ensembl
RefSeq Acc Id: NM_001191909   ⟹   NP_001178838
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr866,124,782 - 6,195,380 (-)NCBI
mRatBN7.26378,779 - 449,382 (-)NCBI
Rnor_6.0618,880,737 - 18,949,393 (+)NCBI
Rnor_5.0628,775,065 - 28,848,187 (+)NCBI
Celera6201,982 - 272,550 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063262232   ⟹   XP_063118302
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr866,121,402 - 6,198,217 (-)NCBI
RefSeq Acc Id: XM_063262233   ⟹   XP_063118303
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr866,121,402 - 6,198,204 (-)NCBI
RefSeq Acc Id: XM_063262234   ⟹   XP_063118304
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr866,121,402 - 6,198,226 (-)NCBI
RefSeq Acc Id: XM_063262236   ⟹   XP_063118306
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr866,121,402 - 6,198,076 (-)NCBI
RefSeq Acc Id: XM_063262237   ⟹   XP_063118307
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr866,121,402 - 6,198,217 (-)NCBI
RefSeq Acc Id: XM_063262238   ⟹   XP_063118308
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr866,121,402 - 6,198,199 (-)NCBI
RefSeq Acc Id: XM_063262239   ⟹   XP_063118309
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr866,121,402 - 6,198,162 (-)NCBI
RefSeq Acc Id: XM_063262240   ⟹   XP_063118310
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr866,121,402 - 6,184,544 (-)NCBI
RefSeq Acc Id: XM_063262241   ⟹   XP_063118311
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr866,121,402 - 6,174,702 (-)NCBI
RefSeq Acc Id: XM_063262242   ⟹   XP_063118312
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr866,144,936 - 6,198,217 (-)NCBI
RefSeq Acc Id: NP_001178838   ⟸   NM_001191909
- UniProtKB: A0A0G2K2X2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072411   ⟸   ENSRNOT00000084222
Ensembl Acc Id: ENSRNOP00000003432   ⟸   ENSRNOT00000003432
RefSeq Acc Id: XP_063118304   ⟸   XM_063262234
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2X2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118307   ⟸   XM_063262237
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K2X2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118302   ⟸   XM_063262232
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2X2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118303   ⟸   XM_063262233
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2X2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118308   ⟸   XM_063262238
- Peptide Label: isoform X3
- UniProtKB: A0A0G2K2X2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118309   ⟸   XM_063262239
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063118306   ⟸   XM_063262236
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2X2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118310   ⟸   XM_063262240
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063118311   ⟸   XM_063262241
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063118312   ⟸   XM_063262242
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000112389   ⟸   ENSRNOT00000131743
Ensembl Acc Id: ENSRNOP00000100756   ⟸   ENSRNOT00000143570

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZK29-F1-model_v2 AlphaFold D3ZK29 1-664 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694414
Promoter ID:EPDNEW_R4928
Type:initiation region
Name:Alkbh8_1
Description:alkB homolog 8, tRNA methyltransferase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0618,877,938 - 18,877,998EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304687 AgrOrtholog
BioCyc Gene G2FUF-38824 BioCyc
BioCyc Pathway PWY-6829 [tRNA methylation (yeast)] BioCyc
  PWY-7888 [tRNA-uridine 2-thiolation (cytoplasmic)] BioCyc
BioCyc Pathway Image PWY-6829 BioCyc
  PWY-7888 BioCyc
Ensembl Genes ENSRNOG00000024525 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000084222.3 UniProtKB/TrEMBL
  ENSRNOT00000131743 ENTREZGENE
  ENSRNOT00000131743.1 UniProtKB/TrEMBL
  ENSRNOT00000143570.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.1520 UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/TrEMBL
  3.40.50.150 UniProtKB/TrEMBL
InterPro AlkB-like UniProtKB/TrEMBL
  AlkB_tRNA_MeTrf/Diox UniProtKB/TrEMBL
  ALKBH8_RRM UniProtKB/TrEMBL
  DUF1891 UniProtKB/TrEMBL
  Methyltransf_11 UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  Oxoglutarate/Fe-dep_oxygenase UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_RNP1 UniProtKB/TrEMBL
  SAM-dependent_MTases-like UniProtKB/TrEMBL
NCBI Gene 366783 ENTREZGENE
PANTHER ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam 2OG-FeII_Oxy_2 UniProtKB/TrEMBL
  DUF1891 UniProtKB/TrEMBL
  Methyltransf_11 UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
PhenoGen Alkbh8 PhenoGen
PROSITE FE2OG_OXY UniProtKB/TrEMBL
  RRM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000024525 RatGTEx
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP Clavaminate synthase-like UniProtKB/TrEMBL
  SSF53335 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt A0A0G2K2X2 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LFY7_RAT UniProtKB/TrEMBL
  A0ABK0M2G8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-01 Alkbh8  alkB homolog 8, tRNA methyltransferase  Alkbh8  alkB, alkylation repair homolog 8 (E. coli)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Alkbh8  alkB, alkylation repair homolog 8 (E. coli)  RGD1304687_predicted  similar to CG17807-PA (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1304687_predicted  similar to CG17807-PA (predicted)  LOC366783_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC366783_predicted  similar to CG17807-PA (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL