C5h1orf174 (similar to human chromosome 1 open reading frame 174) - Rat Genome Database

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Gene: C5h1orf174 (similar to human chromosome 1 open reading frame 174) Rattus norvegicus
Analyze
Symbol: C5h1orf174
Name: similar to human chromosome 1 open reading frame 174
RGD ID: 1304567
Description: Predicted to be located in nucleoplasm. Orthologous to human C1orf174 (chromosome 1 open reading frame 174); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical protein LOC362671; LOC362671; MGC105699; RGD1304567; similar to RIKEN cDNA A430005L14; UPF0688 protein C1orf174 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85169,798,004 - 169,802,449 (+)NCBIGRCr8
mRatBN7.25164,515,578 - 164,520,022 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5164,515,559 - 164,520,021 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5167,219,688 - 167,224,133 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05169,041,096 - 169,045,541 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05169,003,545 - 169,007,990 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05171,242,899 - 171,247,344 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5171,242,897 - 171,247,346 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05174,734,521 - 174,738,966 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45170,743,188 - 170,747,633 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15170,753,682 - 170,758,126 (+)NCBI
Celera5162,727,542 - 162,731,987 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
C5h1orf174
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85169,798,004 - 169,802,449 (+)NCBIGRCr8
mRatBN7.25164,515,578 - 164,520,022 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5164,515,559 - 164,520,021 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5167,219,688 - 167,224,133 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05169,041,096 - 169,045,541 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05169,003,545 - 169,007,990 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05171,242,899 - 171,247,344 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5171,242,897 - 171,247,346 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05174,734,521 - 174,738,966 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45170,743,188 - 170,747,633 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15170,753,682 - 170,758,126 (+)NCBI
Celera5162,727,542 - 162,731,987 (+)NCBICelera
Cytogenetic Map5q36NCBI
C1orf174
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813,889,133 - 3,900,272 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13,889,125 - 3,900,293 (-)EnsemblGRCh38hg38GRCh38
GRCh3713,805,697 - 3,816,836 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3613,795,557 - 3,806,709 (-)NCBINCBI36Build 36hg18NCBI36
Celera13,059,840 - 3,070,495 (-)NCBICelera
Cytogenetic Map1p36.32NCBI
HuRef13,101,393 - 3,112,467 (-)NCBIHuRef
CHM1_113,792,710 - 3,803,318 (-)NCBICHM1_1
T2T-CHM13v2.013,401,037 - 3,412,176 (-)NCBIT2T-CHM13v2.0
A430005L14Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394154,041,694 - 154,046,382 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4154,041,694 - 154,046,382 (+)EnsemblGRCm39 Ensembl
GRCm384153,957,237 - 153,961,925 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4153,957,237 - 153,961,925 (+)EnsemblGRCm38mm10GRCm38
MGSCv374153,331,346 - 153,336,034 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364152,801,037 - 152,805,714 (+)NCBIMGSCv36mm8
Celera4156,245,393 - 156,250,081 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map483.78NCBI
CUNH1orf174
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554867,831,913 - 7,833,898 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554867,821,396 - 7,834,357 (+)NCBIChiLan1.0ChiLan1.0
C1H1orf174
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21224,399,853 - 224,417,162 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11223,041,337 - 223,060,587 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012,563,184 - 2,574,235 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113,682,175 - 3,692,621 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13,682,181 - 3,692,637 (-)Ensemblpanpan1.1panPan2
C5H1orf174
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1558,358,540 - 58,366,356 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl558,359,025 - 58,366,243 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha558,368,835 - 58,376,726 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0558,566,043 - 58,573,933 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl558,566,043 - 58,573,907 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1558,573,741 - 58,581,631 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0558,442,648 - 58,450,536 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0558,832,916 - 58,840,806 (-)NCBIUU_Cfam_GSD_1.0
CUNH1orf174
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505829,372,566 - 29,393,056 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493673772,930 - 78,824 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C6H1orf174
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl665,323,756 - 65,333,886 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1665,326,980 - 65,333,891 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2660,030,404 - 60,037,317 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CUNH1orf174
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120127,780,801 - 127,792,440 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20127,780,903 - 127,791,615 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605431,977,059 - 31,988,521 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH1orf174
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248186,691,432 - 6,698,596 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248186,691,416 - 6,698,288 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in C5h1orf174
5 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:255
Count of miRNA genes:168
Interacting mature miRNAs:187
Transcripts:ENSRNOT00000032859
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000032859   ⟹   ENSRNOP00000038852
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5164,515,559 - 164,520,019 (+)Ensembl
Rnor_6.0 Ensembl5171,242,897 - 171,247,346 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112064   ⟹   ENSRNOP00000085164
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5164,515,618 - 164,520,021 (+)Ensembl
RefSeq Acc Id: NM_001009711   ⟹   NP_001009711
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85169,798,004 - 169,802,449 (+)NCBI
mRatBN7.25164,515,578 - 164,520,022 (+)NCBI
Rnor_6.05171,242,899 - 171,247,344 (+)NCBI
Rnor_5.05174,734,521 - 174,738,966 (+)NCBI
RGSC_v3.45170,743,188 - 170,747,633 (+)RGD
Celera5162,727,542 - 162,731,987 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001009711 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87640 (Get FASTA)   NCBI Sequence Viewer  
  EDL81248 (Get FASTA)   NCBI Sequence Viewer  
  EDL81249 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000038852.5
  ENSRNOP00000085164.1
GenBank Protein Q5M951 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001009711   ⟸   NM_001009711
- UniProtKB: Q5M951 (UniProtKB/Swiss-Prot),   A6IUJ7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000038852   ⟸   ENSRNOT00000032859
Ensembl Acc Id: ENSRNOP00000085164   ⟸   ENSRNOT00000112064

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M951-F1-model_v2 AlphaFold Q5M951 1-222 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694306
Promoter ID:EPDNEW_R4831
Type:initiation region
Name:RGD1304567_1
Description:similar to RIKEN cDNA A430005L14
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05171,242,889 - 171,242,949EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304567 AgrOrtholog
BioCyc Gene G2FUF-38976 BioCyc
Ensembl Genes ENSRNOG00000025034 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032859.6 UniProtKB/TrEMBL
  ENSRNOT00000112064.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7308844 IMAGE-MGC_LOAD
InterPro UPF0688 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:362671 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105699 IMAGE-MGC_LOAD
NCBI Gene 362671 ENTREZGENE
PANTHER PTHR28491 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UPF0688 PROTEIN C1ORF174 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam UPF0688 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen C5h1orf174 PhenoGen
RatGTEx ENSRNOG00000025034 RatGTEx
UniProt A0A8I6A2P3_RAT UniProtKB/TrEMBL
  A6IUJ7 ENTREZGENE, UniProtKB/TrEMBL
  CA174_RAT UniProtKB/Swiss-Prot
  G3V981_RAT UniProtKB/TrEMBL
  Q5M951 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-07-29 C5h1orf174  similar to human chromosome 1 open reading frame 174  RGD1304567  similar to RIKEN cDNA A430005L14  Name and Symbol changed 629549 APPROVED
2006-03-30 RGD1304567  similar to RIKEN cDNA A430005L14    LOC362671  Name updated 1299863 APPROVED
2005-12-06 RGD1304567  LOC362671  RGD1304567_predicted  LOC362671 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1304567_predicted  LOC362671 (predicted)  LOC362671_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362671_predicted  LOC362671 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL