Arl9 (ARF like GTPase 9) - Rat Genome Database

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Pathways
Gene: Arl9 (ARF like GTPase 9) Rattus norvegicus
Analyze
Symbol: Arl9
Name: ARF like GTPase 9 (Ensembl:ADP-ribosylation factor like GTPase 9)
RGD ID: 1303337
Description: Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in nervous system development. Orthologous to human ARL9 (ARF like GTPase 9); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; copper atom.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ADP-ribosylation factor like GTPase 9; ADP-ribosylation factor-like 9; ADP-ribosylation factor-like protein 9
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81431,511,845 - 31,521,038 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1431,511,330 - 31,520,988 (-)EnsemblGRCr8
mRatBN7.21431,157,573 - 31,166,803 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1431,157,586 - 31,166,699 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1431,535,458 - 31,542,678 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01432,843,790 - 32,851,010 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01431,328,463 - 31,335,683 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01433,436,803 - 33,447,516 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1433,436,980 - 33,444,235 (-)Ensemblrn6Rnor6.0
Rnor_5.01433,227,442 - 33,234,397 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41433,452,273 - 33,459,278 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1430,470,801 - 30,478,012 (-)NCBICelera
RGSC_v3.11433,452,272 - 33,459,278 (-)NCBI
Cytogenetic Map14p11NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Information Derived from GenBank Report RGD, Sept. 2003
Additional References at PubMed
PMID:15033445  


Genomics

Comparative Map Data
Arl9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81431,511,845 - 31,521,038 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1431,511,330 - 31,520,988 (-)EnsemblGRCr8
mRatBN7.21431,157,573 - 31,166,803 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1431,157,586 - 31,166,699 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1431,535,458 - 31,542,678 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01432,843,790 - 32,851,010 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01431,328,463 - 31,335,683 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01433,436,803 - 33,447,516 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1433,436,980 - 33,444,235 (-)Ensemblrn6Rnor6.0
Rnor_5.01433,227,442 - 33,234,397 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41433,452,273 - 33,459,278 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1430,470,801 - 30,478,012 (-)NCBICelera
RGSC_v3.11433,452,272 - 33,459,278 (-)NCBI
Cytogenetic Map14p11NCBI
ARL9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38456,505,209 - 56,524,453 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl456,505,209 - 56,524,959 (+)Ensemblhg38GRCh38
GRCh37457,371,375 - 57,390,619 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36457,066,132 - 57,084,815 (+)NCBIBuild 36Build 36hg18NCBI36
Celera454,877,789 - 54,896,005 (+)NCBICelera
Cytogenetic Map4q12NCBI
HuRef453,325,471 - 53,344,157 (+)NCBIHuRef
CHM1_1457,406,511 - 57,425,194 (+)NCBICHM1_1
T2T-CHM13v2.0459,993,215 - 60,012,461 (+)NCBIT2T-CHM13v2.0
Arl9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39577,146,054 - 77,158,806 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl577,151,902 - 77,158,453 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38577,002,744 - 77,010,959 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl577,004,055 - 77,010,606 (+)Ensemblmm10GRCm38
MGSCv37577,433,080 - 77,438,503 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36578,078,830 - 78,084,253 (+)NCBIMGSCv36mm8
Celera574,271,949 - 74,277,364 (+)NCBICelera
Cytogenetic Map5C3.3NCBI
cM Map541.45NCBI
Arl9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544714,500,544 - 14,515,351 (-)Ensembl
ChiLan1.0NW_00495544714,500,696 - 14,515,286 (-)NCBIChiLan1.0ChiLan1.0
ARL9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2373,252,659 - 73,274,538 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1473,458,177 - 73,480,061 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0467,397,990 - 67,418,407 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1473,968,079 - 73,987,737 (-)NCBIPanPan1.1PanPan1.1panPan2
ARL9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11348,719,660 - 48,738,367 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1348,719,798 - 48,738,294 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1348,610,137 - 48,629,042 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01349,333,916 - 49,352,827 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1349,333,927 - 49,352,900 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11349,005,950 - 49,024,852 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01348,534,771 - 48,553,678 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01349,480,849 - 49,499,772 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Arl9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528527,560,083 - 27,575,357 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648218,726,574 - 18,739,081 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648218,722,725 - 18,738,478 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARL9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl855,763,239 - 55,776,645 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1855,762,902 - 55,776,649 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2857,774,056 - 57,786,882 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARL9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1712,105,750 - 12,124,457 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606612,780,478 - 12,800,013 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arl9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476112,901,025 - 12,916,499 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Arl9
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11133,749,064 - 33,756,294 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Arl9
145 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:56
Count of miRNA genes:51
Interacting mature miRNAs:52
Transcripts:ENSRNOT00000044441
Prediction methods:Microtar, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631528Scl11Serum cholesterol level QTL 114.9blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)141787564536079022Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14140068101Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14140068101Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14939329839411170Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143123808072970315Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
2324617Coatc2Coat color QTL 20.001coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)143112133339507682Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14862139853621398Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)141891545442433608Rat
7387267Uae42Urinary albumin excretion QTL 420.61urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)142252151767521517Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141889519263895192Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141790672654251504Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141415516Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14131893212Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14862139853621398Rat

Markers in Region
BF387243  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21431,157,630 - 31,157,805 (+)MAPPERmRatBN7.2
Rnor_6.01433,437,025 - 33,437,199NCBIRnor6.0
Rnor_5.01433,227,487 - 33,227,661UniSTSRnor5.0
RGSC_v3.41433,452,318 - 33,452,492UniSTSRGSC3.4
Celera1430,470,846 - 30,471,020UniSTS
RH 3.4 Map14422.1UniSTS
Cytogenetic Map14p11UniSTS
BF404311  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21431,157,630 - 31,157,845 (+)MAPPERmRatBN7.2
Rnor_6.01433,437,025 - 33,437,239NCBIRnor6.0
Rnor_5.01433,227,487 - 33,227,701UniSTSRnor5.0
RGSC_v3.41433,452,318 - 33,452,532UniSTSRGSC3.4
Celera1430,470,846 - 30,471,060UniSTS
RH 3.4 Map14423.5UniSTS
Cytogenetic Map14p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
2 3 27 74 25 29 9 45 9 1 127 87 8 67 27 52 20 4 4

Sequence


Ensembl Acc Id: ENSRNOT00000044441   ⟹   ENSRNOP00000049745
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1431,513,149 - 31,517,880 (-)Ensembl
mRatBN7.2 Ensembl1431,158,877 - 31,163,610 (-)Ensembl
Rnor_6.0 Ensembl1433,436,980 - 33,444,235 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108975   ⟹   ENSRNOP00000085370
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1431,511,330 - 31,520,988 (-)Ensembl
mRatBN7.2 Ensembl1431,157,586 - 31,166,699 (-)Ensembl
RefSeq Acc Id: NM_212459   ⟹   NP_997624
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81431,511,845 - 31,520,988 (-)NCBI
mRatBN7.21431,157,573 - 31,166,718 (-)NCBI
Rnor_6.01433,436,980 - 33,444,235 (-)NCBI
Rnor_5.01433,227,442 - 33,234,397 (-)NCBI
RGSC_v3.41433,452,273 - 33,459,278 (-)RGD
Celera1430,470,801 - 30,478,012 (-)RGD
Sequence:
RefSeq Acc Id: XM_017599099   ⟹   XP_017454588
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81431,511,858 - 31,521,038 (-)NCBI
mRatBN7.21431,157,585 - 31,166,803 (-)NCBI
Rnor_6.01433,436,803 - 33,447,516 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039091681   ⟹   XP_038947609
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81431,514,779 - 31,521,038 (-)NCBI
mRatBN7.21431,160,508 - 31,166,719 (-)NCBI
RefSeq Acc Id: XM_039091682   ⟹   XP_038947610
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81431,513,926 - 31,521,038 (-)NCBI
mRatBN7.21431,159,290 - 31,166,718 (-)NCBI
RefSeq Acc Id: XR_010057349
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81431,515,744 - 31,521,038 (-)NCBI
RefSeq Acc Id: NP_997624   ⟸   NM_212459
- UniProtKB: A0A8I6A3R6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454588   ⟸   XM_017599099
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000049745   ⟸   ENSRNOT00000044441
RefSeq Acc Id: XP_038947610   ⟸   XM_039091682
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038947609   ⟸   XM_039091681
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000085370   ⟸   ENSRNOT00000108975

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6IMA9-F1-model_v2 AlphaFold Q6IMA9 1-177 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699269
Promoter ID:EPDNEW_R9793
Type:initiation region
Name:Arl9_1
Description:ADP-ribosylation factor like GTPase 9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01433,444,295 - 33,444,355EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303337 AgrOrtholog
BioCyc Gene G2FUF-15972 BioCyc
Ensembl Genes ENSRNOG00000029628 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000044441.3 UniProtKB/TrEMBL
  ENSRNOT00000108975 ENTREZGENE
  ENSRNOT00000108975.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro Arf-like_GTPase UniProtKB/TrEMBL
  ARF/SAR UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP_bd UniProtKB/TrEMBL
KEGG Report rno:289565 UniProtKB/TrEMBL
NCBI Gene 289565 ENTREZGENE
PANTHER ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 9 UniProtKB/TrEMBL
  ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 9-RELATED UniProtKB/TrEMBL
Pfam Arf UniProtKB/TrEMBL
PhenoGen Arl9 PhenoGen
PRINTS SAR1GTPBP UniProtKB/TrEMBL
PROSITE ARF UniProtKB/TrEMBL
RatGTEx ENSRNOG00000029628 RatGTEx
SMART ARF UniProtKB/TrEMBL
  SAR UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8I6A3R6 ENTREZGENE, UniProtKB/TrEMBL
  A6JCW3_RAT UniProtKB/TrEMBL
  F7F2I5_RAT UniProtKB/TrEMBL
  Q6IMA9_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-11-07 Arl9  ARF like GTPase 9  Arl9  ADP-ribosylation factor like GTPase 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-19 Arl9  ADP-ribosylation factor like GTPase 9  Arl9  ADP-ribosylation factor-like 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Arl9  ADP-ribosylation factor-like 9      Symbol and Name status set to approved 1299863 APPROVED
2005-02-14 Arl9  ADP-ribosylation factor-like 9      Symbol and Name status set to provisional 70820 PROVISIONAL