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Gene: Eml5 (EMAP like 5) Rattus norvegicus

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Symbol:

Eml5

Name:

EMAP like 5

RGD ID:

1303275

Description:

Predicted to enable microtubule binding activity. Predicted to be located in cytoplasm and microtubule. Orthologous to human EML5 (EMAP like 5); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

echinoderm microtubule associated protein like 5; echinoderm microtubule-associated protein-like 5; EMAP-5; EMAP-like protein 5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EML5 (EMAP like 5)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Eml5 (echinoderm microtubule associated protein like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Eml5 (EMAP like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EML5 (EMAP like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EML5 (EMAP like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Eml5 (EMAP like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EML5 (EMAP like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EML5 (EMAP like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Eml5 (EMAP like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	EML6 (EMAP like 6)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	EML5 (EMAP like 5)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Eml5 (echinoderm microtubule associated protein like 5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-1f12.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	eml5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	123,775,269 - 123,905,585 (-)	NCBI		GRCr8
mRatBN7.2	6	118,046,655 - 118,175,831 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	118,046,655 - 118,175,831 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	118,197,287 - 118,325,751 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	118,494,088 - 118,622,546 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	117,828,943 - 117,957,398 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	122,768,939 - 122,898,046 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	122,770,055 - 122,897,997 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	131,989,998 - 132,118,760 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	122,958,412 - 123,087,547 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	122,973,904 - 123,091,229 (-)	NCBI
Celera	6	115,606,223 - 115,734,030 (-)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eml5	Rat	Bardet-Biedl syndrome		ISO	EML5 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Bardet-Biedl syndrome	ClinVar	PMID:28492532
Eml5	Rat	Leber congenital amaurosis 3		ISO	EML5 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Leber congenital amaurosis 3	ClinVar	PMID:28492532

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eml5	Rat	1,2-dichloroethane	decreases expression	ISO	Eml5 (Mus musculus)	6480464	ethylene dichloride results in decreased expression of EML5 mRNA	CTD	PMID:28960355
Eml5	Rat	1,2-dimethylhydrazine	increases expression	ISO	Eml5 (Mus musculus)	6480464	1 and 2-Dimethylhydrazine results in increased expression of EML5 mRNA	CTD	PMID:22206623
Eml5	Rat	17beta-estradiol	decreases expression	EXP		6480464	Estradiol results in decreased expression of EML5 mRNA	CTD	PMID:35192832
Eml5	Rat	2,3',4,4',5-Pentachlorobiphenyl	decreases expression	ISO	Eml5 (Mus musculus)	6480464	2 more ...	CTD	PMID:31388691
Eml5	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Eml5 (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of EML5 mRNA	CTD	PMID:21570461
Eml5	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of EML5 mRNA	CTD	PMID:33387578
Eml5	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of EML5 mRNA	CTD	PMID:32109520
Eml5	Rat	2,4-dinitrotoluene	affects expression	EXP		6480464	2 and 4-dinitrotoluene affects the expression of EML5 mRNA	CTD	PMID:21346803
Eml5	Rat	2-methylcholine	affects expression	ISO	EML5 (Homo sapiens)	6480464	beta-methylcholine affects the expression of EML5 mRNA	CTD	PMID:21179406
Eml5	Rat	3,4-methylenedioxymethamphetamine	decreases expression	EXP		6480464	N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of EML5 mRNA	CTD	PMID:30071829
Eml5	Rat	6-propyl-2-thiouracil	decreases expression	EXP		6480464	Propylthiouracil results in decreased expression of EML5 mRNA	CTD	PMID:30047161
Eml5	Rat	amitrole	decreases expression	EXP		6480464	Amitrole results in decreased expression of EML5 mRNA	CTD	PMID:30047161
Eml5	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of EML5 mRNA	CTD	PMID:25181051 more ...
Eml5	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of EML5 mRNA	CTD	PMID:35192832
Eml5	Rat	bisphenol A	multiple interactions	ISO	EML5 (Homo sapiens)	6480464	[bisphenol A co-treated with Fulvestrant] results in increased methylation of EML5 gene	CTD	PMID:31601247
Eml5	Rat	bisphenol A	decreases expression	ISO	Eml5 (Mus musculus)	6480464	bisphenol A results in decreased expression of EML5 mRNA	CTD	PMID:32156529 and PMID:33221593
Eml5	Rat	bisphenol A	decreases expression	ISO	EML5 (Homo sapiens)	6480464	bisphenol A results in decreased expression of EML5 mRNA	CTD	PMID:29275510
Eml5	Rat	bisphenol A	decreases methylation	ISO	Eml5 (Mus musculus)	6480464	bisphenol A results in decreased methylation of EML5 promoter	CTD	PMID:27312807
Eml5	Rat	bisphenol F	decreases expression	ISO	Eml5 (Mus musculus)	6480464	bisphenol F results in decreased expression of EML5 mRNA	CTD	PMID:38685157
Eml5	Rat	CGP 52608	multiple interactions	ISO	EML5 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to EML5 gene]	CTD	PMID:28238834
Eml5	Rat	cisplatin	decreases expression	ISO	EML5 (Homo sapiens)	6480464	Cisplatin results in decreased expression of EML5 mRNA	CTD	PMID:27392435
Eml5	Rat	cisplatin	multiple interactions	ISO	EML5 (Homo sapiens)	6480464	[Cisplatin co-treated with jinfukang] results in decreased expression of EML5 mRNA	CTD	PMID:27392435
Eml5	Rat	coumarin	decreases phosphorylation	ISO	EML5 (Homo sapiens)	6480464	coumarin results in decreased phosphorylation of EML5 protein	CTD	PMID:35688186
Eml5	Rat	cyclosporin A	increases expression	ISO	EML5 (Homo sapiens)	6480464	Cyclosporine results in increased expression of EML5 mRNA	CTD	PMID:27989131
Eml5	Rat	Dibutyl phosphate	affects expression	ISO	EML5 (Homo sapiens)	6480464	di-n-butylphosphoric acid affects the expression of EML5 mRNA	CTD	PMID:37042841
Eml5	Rat	diquat	decreases expression	ISO	Eml5 (Mus musculus)	6480464	Diquat results in decreased expression of EML5 mRNA	CTD	PMID:36851058
Eml5	Rat	endosulfan	decreases expression	EXP		6480464	Endosulfan results in decreased expression of EML5 mRNA	CTD	PMID:29391264
Eml5	Rat	epoxiconazole	decreases expression	ISO	Eml5 (Mus musculus)	6480464	epoxiconazole results in decreased expression of EML5 mRNA	CTD	PMID:35436446
Eml5	Rat	ethanol	decreases expression	ISO	Eml5 (Mus musculus)	6480464	Ethanol results in decreased expression of EML5 mRNA	CTD	PMID:29018328
Eml5	Rat	fulvestrant	multiple interactions	ISO	EML5 (Homo sapiens)	6480464	[bisphenol A co-treated with Fulvestrant] results in increased methylation of EML5 gene	CTD	PMID:31601247
Eml5	Rat	furan	decreases expression	EXP		6480464	furan results in decreased expression of EML5 mRNA	CTD	PMID:26194646
Eml5	Rat	gentamycin	increases expression	EXP		6480464	Gentamicins results in increased expression of EML5 mRNA	CTD	PMID:33387578
Eml5	Rat	indole-3-methanol	affects expression	EXP		6480464	indole-3-carbinol affects the expression of EML5 mRNA	CTD	PMID:21396975
Eml5	Rat	methimazole	decreases expression	EXP		6480464	Methimazole results in decreased expression of EML5 mRNA	CTD	PMID:30047161
Eml5	Rat	methylmercury chloride	increases expression	ISO	EML5 (Homo sapiens)	6480464	methylmercuric chloride results in increased expression of EML5 mRNA	CTD	PMID:28001369
Eml5	Rat	N,N-diethyl-m-toluamide	multiple interactions	EXP		6480464	[Permethrin co-treated with DEET] results in increased methylation of EML5 gene	CTD	PMID:33148267
Eml5	Rat	paracetamol	increases expression	ISO	EML5 (Homo sapiens)	6480464	Acetaminophen results in increased expression of EML5 mRNA	CTD	PMID:29067470
Eml5	Rat	paracetamol	increases expression	EXP		6480464	Acetaminophen results in increased expression of EML5 mRNA	CTD	PMID:33387578
Eml5	Rat	permethrin	multiple interactions	EXP		6480464	[Permethrin co-treated with DEET] results in increased methylation of EML5 gene	CTD	PMID:33148267
Eml5	Rat	phenobarbital	affects expression	ISO	Eml5 (Mus musculus)	6480464	Phenobarbital affects the expression of EML5 mRNA	CTD	PMID:23091169
Eml5	Rat	potassium dichromate	decreases expression	ISO	Eml5 (Mus musculus)	6480464	Potassium Dichromate results in decreased expression of EML5 mRNA	CTD	PMID:23608068
Eml5	Rat	rotenone	decreases expression	EXP		6480464	Rotenone results in decreased expression of EML5 mRNA	CTD	PMID:28374803
Eml5	Rat	sodium arsenite	increases expression	ISO	EML5 (Homo sapiens)	6480464	sodium arsenite results in increased expression of EML5 mRNA	CTD	PMID:34032870 and PMID:38568856
Eml5	Rat	sunitinib	decreases expression	ISO	EML5 (Homo sapiens)	6480464	Sunitinib results in decreased expression of EML5 mRNA	CTD	PMID:31533062
Eml5	Rat	tanespimycin	increases expression	ISO	EML5 (Homo sapiens)	6480464	tanespimycin analog results in increased expression of EML5 protein	CTD	PMID:31370342
Eml5	Rat	tanespimycin	multiple interactions	ISO	EML5 (Homo sapiens)	6480464	[tanespimycin co-treated with VER 155008] results in increased expression of EML5 protein	CTD	PMID:31370342
Eml5	Rat	thimerosal	increases expression	ISO	EML5 (Homo sapiens)	6480464	Thimerosal results in increased expression of EML5 mRNA	CTD	PMID:27188386
Eml5	Rat	thioacetamide	decreases expression	EXP		6480464	Thioacetamide results in decreased expression of EML5 mRNA	CTD	PMID:23411599 and PMID:34492290
Eml5	Rat	titanium dioxide	decreases expression	ISO	Eml5 (Mus musculus)	6480464	titanium dioxide results in decreased expression of EML5 mRNA	CTD	PMID:29264374
Eml5	Rat	titanium dioxide	decreases methylation	ISO	Eml5 (Mus musculus)	6480464	titanium dioxide results in decreased methylation of EML5 gene	CTD	PMID:35295148
Eml5	Rat	triadimefon	decreases expression	EXP		6480464	triadimefon results in decreased expression of EML5 mRNA	CTD	PMID:30047161
Eml5	Rat	trichloroethene	decreases expression	EXP		6480464	Trichloroethylene results in decreased expression of EML5 mRNA	CTD	PMID:33387578
Eml5	Rat	triphenyl phosphate	affects expression	ISO	EML5 (Homo sapiens)	6480464	triphenyl phosphate affects the expression of EML5 mRNA	CTD	PMID:37042841
Eml5	Rat	valproic acid	increases expression	ISO	EML5 (Homo sapiens)	6480464	Valproic Acid results in increased expression of EML5 mRNA	CTD	PMID:24383497
Eml5	Rat	valproic acid	affects splicing	EXP		6480464	Valproic Acid affects the splicing of EML5 mRNA	CTD	PMID:29427782
Eml5	Rat	valproic acid	decreases expression	EXP		6480464	Valproic Acid results in decreased expression of EML5 mRNA	CTD	PMID:29427782
Eml5	Rat	vinclozolin	increases expression	EXP		6480464	vinclozolin results in increased expression of EML5 mRNA	CTD	PMID:23034163 and PMID:23555832

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eml5	Rat	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Eml5	Rat	cytoskeleton	located_in	IEA	UniProtKB-SubCell:SL-0090	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Eml5	Rat	cytoskeleton	located_in	IEA	UniProtKB-KW:KW-0206	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Eml5	Rat	microtubule	located_in	IEA	UniProtKB-KW:KW-0493	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Eml5	Rat	microtubule binding	enables	IBA	FB:FBgn0259099 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Eml5, a novel WD40 domain protein expressed in rat brain.	O'Connor V, etal., Gene 2004 Jul 7;336(1):127-37.
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:12477932	PMID:19056867	PMID:36307995

Eml5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	123,775,269 - 123,905,585 (-)	NCBI		GRCr8
mRatBN7.2	6	118,046,655 - 118,175,831 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	118,046,655 - 118,175,831 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	118,197,287 - 118,325,751 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	118,494,088 - 118,622,546 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	117,828,943 - 117,957,398 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	122,768,939 - 122,898,046 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	122,770,055 - 122,897,997 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	131,989,998 - 132,118,760 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	122,958,412 - 123,087,547 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	122,973,904 - 123,091,229 (-)	NCBI
Celera	6	115,606,223 - 115,734,030 (-)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

EML5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	88,612,431 - 88,792,953 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	88,612,431 - 88,792,953 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	89,078,775 - 89,259,297 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	88,150,954 - 88,328,910 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	88,150,956 - 88,328,910	NCBI
Celera	14	69,126,811 - 69,307,471 (-)	NCBI		Celera
Cytogenetic Map	14	q31.3	NCBI
HuRef	14	69,251,426 - 69,434,464 (-)	NCBI		HuRef
CHM1_1	14	89,019,033 - 89,196,906 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	82,833,321 - 83,016,566 (-)	NCBI		T2T-CHM13v2.0

Eml5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	98,752,863 - 98,867,770 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	98,753,064 - 98,867,743 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	98,786,604 - 98,901,511 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	98,786,805 - 98,901,484 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	100,024,814 - 100,139,694 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	99,187,654 - 99,302,534 (-)	NCBI		MGSCv36	mm8
Celera	12	100,012,303 - 100,127,197 (-)	NCBI		Celera
Cytogenetic Map	12	E	NCBI
cM Map	12	49.88	NCBI

Eml5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955438	11,226,458 - 11,353,129 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955438	11,225,910 - 11,366,996 (-)	NCBI	ChiLan1.0	ChiLan1.0

EML5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	89,762,137 - 89,942,940 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	88,978,644 - 89,159,447 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	69,233,075 - 69,416,483 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	88,590,141 - 88,772,323 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	88,590,141 - 88,774,705 (-)	Ensembl	panpan1.1		panPan2

EML5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	59,850,400 - 60,033,245 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	59,853,379 - 60,033,906 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	59,428,164 - 59,610,985 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	60,119,892 - 60,302,646 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	60,119,984 - 60,303,239 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	59,798,834 - 59,981,830 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	59,844,113 - 60,032,955 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	60,178,155 - 60,361,241 (-)	NCBI		UU_Cfam_GSD_1.0

Eml5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	15,828,780 - 16,010,646 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936488	16,062,766 - 16,240,188 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936488	16,061,132 - 16,240,182 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EML5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	110,512,079 - 110,705,441 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	110,511,937 - 110,705,452 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	117,009,391 - 117,173,408 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EML5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	66,249,880 - 66,451,844 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	66,253,225 - 66,451,463 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	53,608,870 - 53,799,753 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Eml5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	13,530,532 - 13,732,868 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	13,530,116 - 13,733,022 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Eml5
603 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	115
Count of miRNA genes:	101
Interacting mature miRNAs:	105
Transcripts:	ENSRNOT00000005978, ENSRNOT00000057601
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12801411	Schws8	Schwannoma susceptibility QTL 8			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	94968928	139968928	Rat
1331797	Bp213	Blood pressure QTL 213	3.291		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	104085867	128713626	Rat
4145118	Mcs26	Mammary carcinoma susceptibility QTL 26		0.0001	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	6	106752656	132339866	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	72202632	130919985	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	72227641	130729205	Rat
10054138	Gmadr3	Adrenal mass QTL 3	3.68	0.00045	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	6	85140138	130140138	Rat
61414	Pia3	Pristane induced arthritis QTL 3	4.5		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	6	94968928	137848904	Rat
71111	Iddm8	Insulin dependent diabetes mellitus QTL 8	1.9	0.002	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	6	105156861	140994061	Rat
1358355	Srcrt4	Stress Responsive Cort QTL 4	6.39		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	100364669	140994061	Rat
724513	Uae14	Urinary albumin excretion QTL 14	6.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	85311061	133478515	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	88047916	133047916	Rat
731173	Uae22	Urinary albumin excretion QTL 22	10.1		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
10054123	Srcrt6	Stress Responsive Cort QTL 6	2.5	0.0043	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	85140138	130140138	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	72202632	130729475	Rat
737976	Pia24	Pristane induced arthritis QTL 24			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	6	112636280	140994061	Rat
2313399	Anxrr28	Anxiety related response QTL 28			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	6	100671796	132340886	Rat
1298087	Iddm18	Insulin dependent diabetes mellitus QTL 18		0.0001	urine glucose amount (VT:0001758)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	6	116506292	130245370	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	72227641	130729205	Rat
738034	Anxrr5	Anxiety related response QTL 5	5.9		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	6	84130881	129130881	Rat
1331725	Bp212	Blood pressure QTL 212	3.52475		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	93701310	128713626	Rat
2290393	Uae37	Urinary albumin excretion QTL 37		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
8552796	Vie3	Viral induced encephalitis QTL 3	2.6		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	6	96833997	140994061	Rat
1300076	Glom8	Glomerulus QTL 8	7	9e-09	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	6	86894788	131894788	Rat

RH131268

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	118,045,603 - 118,045,788 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	122,769,004 - 122,769,188	NCBI	Rnor6.0
Rnor_5.0	6	131,990,335 - 131,990,519	UniSTS	Rnor5.0
RGSC_v3.4	6	122,958,477 - 122,958,661	UniSTS	RGSC3.4
Celera	6	115,605,172 - 115,605,356	UniSTS
RH 3.4 Map	6	870.1	UniSTS
Cytogenetic Map	6	q32	UniSTS

RH137891

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	118,057,458 - 118,057,624 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	122,780,859 - 122,781,024	NCBI	Rnor6.0
Rnor_5.0	6	132,002,190 - 132,002,355	UniSTS	Rnor5.0
RGSC_v3.4	6	122,970,332 - 122,970,497	UniSTS	RGSC3.4
Celera	6	115,617,027 - 115,617,192	UniSTS
RH 3.4 Map	6	870.39	UniSTS
Cytogenetic Map	6	q32	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	10	49	113	89	88	57	25	57	6	215	96	93	45	60	31


RefSeq Transcripts	NM_001003402	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003750213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764827	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594264	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594265	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262248	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262249	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262250	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262251	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262252	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262253	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262255	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262256	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262257	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262258	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262259	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262260	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010052132	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC098929	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC117104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY445136	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC092620	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000057601 ⟹ ENSRNOP00000054411

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	118,046,655 - 118,175,831 (-)	Ensembl
Rnor_6.0 Ensembl	6	122,770,055 - 122,897,997 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096031 ⟹ ENSRNOP00000093290

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	118,046,655 - 118,175,831 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114559 ⟹ ENSRNOP00000096447

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	118,047,104 - 118,175,831 (-)	Ensembl

RefSeq Acc Id:

NM_001003402 ⟹ NP_001003402

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,776,368 - 123,905,538 (-)	NCBI
mRatBN7.2	6	118,046,655 - 118,175,831 (-)	NCBI
Rnor_6.0	6	122,770,055 - 122,897,997 (-)	NCBI
Rnor_5.0	6	131,989,998 - 132,118,760 (-)	NCBI
Celera	6	115,606,223 - 115,734,030 (-)	NCBI

Sequence:

show sequence

CCTGAGCGCCGCAGGTGACCCGGGCAGGGAGTCCGGTGCGCGGAGCCGGCTGAGAAGGAGCAGGCTGGAGGCGGGTCCCCGTCCCCCCTCTTAGCTTGGTTGTCTCCTAGCCTAGGCACTGGGCTGAG
GGGACACGGCGAGCTCCCAGACGCGCGAGGCTCCCGGACGGCCGGCGGCGCTCGCGGCCCTCAGCATGTTTGGTGAGGCGAGGCTTTTCCTCCCGCCCGTGGGCTGAGGCGACGACGGCGGCCACGCA
AGCGAGATGCACCTGCCGGGCTCGGCTTAGAGGAGCGTCCCGGCCGCCAGCGGGAGAGCTTTCGTCACCCGGCCCCGGCGGCGATCGCGGGCCCGAGCCGCAGCGACGGGTGGGCGCACGGACATGGC
GGCTCGGAGCGCCCCGAGCTGCCACCTGCGGCTCGAGTGGGTGTACGGCTACCGGGGCCACCAGTGCCGCAACAACCTCTACTACACCGCGGCCAAGGAGATCGTGTACTTCGTGGCGGGGGTCGGCG
TCGTGTATAGCCCGCGGGAGCATCGGCAGAAGTTCTACCGCGGCCACAGCGACGACATCATCAGTCTCGCACTGCATCCTGAGCGCGTGTTGGTAGCAACAGGACAAGTTGGGAAAGAGCCTTACATC
TGTGTTTGGGATTCTTACACGGTCCAGACTGTGTCGGTTCTGAAGGACGTTCATACACATGGTATAGCTTGTTTAGCATTTGACTTGGATGGACAGCGCTTAGTTTCAGTTGGACTCGATTCAAAGAA
TGCAGTTTGTGTTTGGGACTGGAAAAGGGGGAAAATGCTGTCTATGGCTCCTGGTCACACAGACAGAATATTTGATATTTCTTGGGATTTGTACCAGCCAAATAAGCTCGTCAGCTGCGGTGTTAAAC
ACATCAAGTTCTGGAGTTTGTGTGGAAATGCTCTGACCCCAAAACGAGGAGTTTTTGGTAAAACAGGTGACCTTCAGACAATATTGTGCCTAGCCTGTGCTCGGGACGAATTAACATATTCTGGTGCA
CTCAATGGCGATATATATGTTTGGAAAGGAATCAATCTTATACGAACAATACAAGGAGCCCATACTGCAGGGATTTTTAGTATGAATGCTTGTGAAGAAGGCTTTGCTACTGGAGGCAGAGATGGCTG
TATTCGTCTTTGGGATTTAACTTTTAAACCAATTACTGTGATTGATCTCAGGGAAACAGAACAGGGATACAAAGGTTTATCTGTGAGGAGTGTTTGTTGGCGAGGTGACCACATTTTAGTGGGAACAC
AGGACAGTGAAATTTTTGAAATTGTTGTGCATGAAAGAAATAAACCTTTCCTAATTATGCAAGGGCATTGCGAAGGTGAACTTTGGGCGCTTGCTGTTCACCCTACTAAGCCTTTGGCTGTAACCGGA
AGTGATGATCGTTCAGTCAGGATTTGGAGCCTTGTAGATCATGCTCTAATAGCGAGATGTAATATGGACGAGCCAATCCGATGTGCCGCTGTCAATGCCGACGGAGTCCACCTCGCCCTTGGAATGAA
GGATGGGTCACTCACTGTCCTTAGAGTGAGAGATATGACTGAAGTTGTACATATTAAAGACAGGAAAGAAGCAATCCATGAGCTGAAATATTCTCCAGATGGCACTTACCTTGCGGTTGGCTGCAATG
ACAGCTCAGTTGACATCTATGGAGTTGCTCAGCGTTACAAAAAAGTGGGTGAATGCGTCGGTTCCCTTAGCTTCATCACTCATTTGGATTGGTCTTCAGACAGTAAATACTTACAGACAAATGACGGC
AGTGGGAAACGACTTCTCTACAAGATGCCAGGAGGAAAGGAAGTGACAAGCAAAGAAGAAGTAAAAGGCATGCACTGGGCTTCATGGACGTGTGTTGCAGGCCTTGAAGTCAATGGAATTTGGCCCAA
GTATTCTGACATCAATGATATAAACTCAGTAGATGGAAACTATGTTGGCCAGGTTTTAGTTACAGCTGATGACTATGGAGTTGTAAAATTATTCCGATATCCATGTTTAAGAAAAGGGGCCAAGTTCA
GAAAATACATTGGCCATTCAGCTCATGTAACTAATGTCAGATGGTCACATGATTACCAGTGGGTTATTTCTATTGGTGGAGCGGATCACTCTGTCTTTCAGTGGAAATTTATTCCTGAGAGAAAATTA
AAAGATGCTCTTCACATAGCACCGCAAGAAAGTCTGACTGAGTCCAACAGCGATGAATCAGATTCAGATCTGTCTGATGTTCCGGAACTAGATTCTGAGATTGAGCAAGAGACACAGCTTACTTACCA
CCGGCAGGTTTACAAAGAAGATCTACCTCAACTCAAAGAACAATGCAAAGAGAAGCAGAAAAGTGCTACTTCTAAACGAAGAGAACGTGCTCCAGGAAATAGTATTCGATTACACTTCATTCATGGTT
ACAGAGGTTATGACTGTCGAAGCAATCTTTTCTACACTCAAATTGGTGAAATTGTGTACCATGTAGCAGCAGTGGGTGTCATATATAATAGACAACAGAACACTCAGCGTTTTTACTTGGGTCATGAT
GATGATATCCTGTGTCTGGCTATTCATCCTTTGAAAGACTATGTGGCAACAGGCCAGGTTGGTAGAGATCCCTCAATTCACGTCTGGGACACAGAAACCATTAAACCATTGTCTATATTAAAGGGCTA
CCACCAATATGGCATCTGTGCTGTGGATTTCTCAGCTGATGGGAAACGCCTAGCTTCAGTTGGAATAGATGACAGCCACACCATTGTATTGTGGGATTGGAAGAAAGGGGAGAAACTTTCAGTGGCAA
GAGGCAGTAAAGATAAGATTTTTGTTGTGAAAATGAACCCCTATGTGCCTGATAAACTAATTACAGCTGGGATTAAACACATGAAATTTTGGCGTAGAGCAGGGGGAGGGCTAATTGGAAGAAAAGGC
TACGTCGGCACTCTGGGGAAAAATGACACAATGATGTGTGCAGTGTATGGATGGACTGAAGAGATGGCTTTTTCTGGAACATCCACAGGAGATGTATGCATCTGGAGAGATGTCTTTCTTGTAAAAAC
AGTTAAAGCCCATGATGGGCCCGTGTTCAGTATGCACGCATTGGAGAAAGGATTTGTAACTGGAGGAAAAGATGGCGTGGTAGCCCTTTGGGATGATTCCTTTGAAAGATGTCTCAAGACTTATGCTA
TAAAAAGAGCTGATTTAGCCCCAGGATCTAAAGGTCTGCTCTTGGAAGATAACCCATCTATACGTGCCATATCATTAGGACATGGTCATATTCTGGTTGGCACAAAGAACGGTGAGATATTGGAAGTG
GATAAAAGTGGCCCAGTCACTCTGCTGGTCCAGGGACACATGGAAGGAGAGGTGTGGGGTTTGGCCACACATCCTTATCTGCCCATCTGTGCTACTGTAAGTGATGATAAGACCTTAAGAATATGGGA
TCTCTCTCCTAGTCATTGTATGTTGGCAGTCCGGAAACTGAAGAAGGGTGGGCGGTGCTGCTGCTTTTCCCCTGATGGCAAAGCTTTGGCTGTAGGACTCAATGATGGAAGCTTCTTGATGGCCAACG
CAGACACTCTAGAGGATCTTGTGTCCTTTCACCACAGAAAAGATGTTATTTCAGACATCCAGTTTTCACCTGGTTCTGGGAAATACCTCGCTGTGGCGTCCCATGACAGCTTCGTTGATATATACAAT
GTGACAAGTAGCAAGCGAGTGGGAGTTTGCAAAGGAGCAACAAGCTACATCACCCACATCGACTGGGACAGCAGAGGAAAGCTTTTACAGGTCAACACTGGTGCTAAAGAACAGCTATTCTTCGAAGC
TCCCAGAGGGAAAAAACAAACCATCCCCAGTGTGGAGGTGGAAAAAATTAGTTGGGCGACATGGACAAGTGTTCTTGGTTTATGTTGTGAGGGAATTTGGCCAATAATTGGAGAAGTCACAGATGTAA
CCGCCTCTTGCCTCACCAGTGACAAAATGGTCCTAGCTACAGGGGATGACTTGGGATTCGTGAAGCTGTTCAGATACCCAGCTAAAGGAAAATTTGGAAAGTTTAAGAAGTATGTGGCTCACAGCACA
CACGTCACAAATGTTCGCTGGACTTACGATGACAGCATGCTGGTTACCCTGGGAGGAGCAGATATGTCCTTAATGGTATGGACAAGTGAAGTGGAGAGACATCGGGAAAAGAAGAACTGTGACAGTGA
AGAGTCTGATACAGATTCTGAAGAAGATGGAGGCTATGACAGCGATGTTACAAGAGAGAATGAAATTAGCTACACCATCAGAGCCTTATCAACTAATATCCGCCCAATGTTTGGAGTCAAGCCTCATT
TGCAACAGAAAGAGCCCTCAGTTGATGAAAGACAGGGGGTAGTAAGAGGATCCAGGCCTCCAGTGAGTAGGGCCCCACCACAGCCCGAGAAACTTCAGTCAAACAATGTAGGCAAGAAGAAGAGACCC
ATAGAGGACCTTGTGTTGGAGCTCGCTTTTGGCTATCGGGGCAGAGACTGCAGGAACAATGTGCACTACTTAAATGACGGTGATGATATAATTTATCACACCGCCTCTGTTGGAATTCTGCACAATGT
TGCCACAGGGACTCAGAGTTTTTATCAAGAGCATAATGATGATATTCTGTGCCTCACTGTAAATCAGCACCCCAAGTTTATCAACATAGTGGCAACTGGCCAAGTAGGTGATTCTGCAGACATGTCAG
CTACAGCCCCATCTGTCCACATCTGGGATGCAGTGAACAAGCAGACATTGTCTATACTAAGATGCTCCCATTCAAAGGGCGTGTGTTCTGTCAGCTTCAGTGCTACTGGGAAGCTGCTGCTGTCTGTA
GGGCTAGACCCAGAGCACACTGTTACCATTTGGAGATGGCAGGAAGGGGCCAAAATTGCCAGCAGAGGTGGGCACAACCAACGTATTTTTGTAGCAGAATTTCGACCAGATTCAGATACCCAGTTTGT
CTCTGTGGGTATAAAGCACGTGAAGTTCTGGACCCTGGCAGGAAGGGCTCTTCTCAGCAAAAAGGGGCTTCTGAGCACCCTGGAGGATGCCCGGATGCAGACGATGCTCGCTGTTGCATTTGGTGCAA
ATAACTTGACGTTTACAGGTACCATCAGTGGTGATGTCTGTGTGTGGAAAGATCACATATTGTGTAGAGTGGTGGCTAGAGCACACAATGGGCCTGTGTTTGCCATGTACACCACCCTGCGAGATGGA
CTGATTGTGACCGGTGGCAAAGAAAGGCCGTCAAAGGAAGGAGGTGCGGTTAAACTGTGGGATCAGGAACTGCGGCGATGCCGGGCCTTCAGGCTTGAGACGGGACAAGTCACAGATTGTGTTCGGTC
TGTGTGCAGAGGCAAAGGCAAGATACTAGTTGGAACAAGGAATTCGGAAATAATTGAAGTTGGGGAGAAAAATGCAGCATGTAACATTTTAGTTAATGGTCATGTGGATGGACCAATCTGGGGACTAG
CAACACATCCTTCCAGGGATTTCTTCCTTTCTGCTGCTGAAGATGGAACAGTGAGACTCTGGGACATTGCTGATAAAAAGATGCTAAACAAAGTGAATTTGGGACATGCTGCTCGGACAGTATGTTAC
AGCCCCGAAGGCGACATGGTGGCTATTGGAATGAAAAATGGAGAATTTATTATATTACTTGTGAGTTCTCTAAAAATATGGGGAAAGAAGAGAGACAGGCGATGTGCAATCCATGATATCAGATTTAG
TCCAGATTCCCGGTATTTGGCAGTGGGTTCCAGTGAGAACTCGGTGGACTTTTATGACCTGACATTGGGTCCCACCCTTAACAGAATCAGCTACTGCAAAGACATTCCAAGCTTTGTCATTCAGATGG
ACTTCTCTGCAGATAGCAGACATCTCCAGGTTTCTAGTGGCTGCTATAAACGGCATGTCTATGAAGTGCCTTCAGGAAAACACCTTGTGGATCATGCTGCCATTGACAGGATCACGTGGGCTACCTGG
ACTAGTATTCTAGGTGATGAAGTTATGGGAATCTGGTCCAGACATGCTGAGAAGGCAGATGTCACCTGTGCCTGTGTGTCTCACTCAGGAATCAGCCTTGTGACAGGAGATGACTTTGGCATGGTTAA
ATTATATGACTTTCCATGCCCAGAAAAATTTGCAAAACACAAGAGGTTCTTGGGTCATTCCCCTCATGTGACAAATATTCGATTTACCAGTGGTGATCGACATGTTGTCAGTGCTGGAGGCGATGACT
GCAGCTTGCTTGTCTGGAAATGTGTACACACGCCTCATTGAAAGTTACGATGCTGAGAAGACTAAACAAATCTCACCTCAAGAGAGCAGTTCCACGTCGGAAAAACCAAAACCAAACTGTGTGGTCAA
GTGGTGCTAACTGAAGACTGTGACAGGGAGGGATGTCCAGAATCATCCACACAGCAGCAGACAGTTCAAAATGCTTGCTGTGCGTACCAACCCATAGTCCACACACTGCCAGATAATTACACTACAAG
GAATGACTGAGC

hide sequence

RefSeq Acc Id:

XM_063262248 ⟹ XP_063118318

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,775,269 - 123,905,585 (-)	NCBI

RefSeq Acc Id:

XM_063262249 ⟹ XP_063118319

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,775,269 - 123,905,585 (-)	NCBI

RefSeq Acc Id:

XM_063262250 ⟹ XP_063118320

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,775,269 - 123,905,585 (-)	NCBI

RefSeq Acc Id:

XM_063262251 ⟹ XP_063118321

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,775,269 - 123,905,585 (-)	NCBI

RefSeq Acc Id:

XM_063262252 ⟹ XP_063118322

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,777,747 - 123,905,585 (-)	NCBI

RefSeq Acc Id:

XM_063262253 ⟹ XP_063118323

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,777,581 - 123,905,585 (-)	NCBI

RefSeq Acc Id:

XM_063262254 ⟹ XP_063118324

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,783,422 - 123,905,585 (-)	NCBI

RefSeq Acc Id:

XM_063262255 ⟹ XP_063118325

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,775,269 - 123,863,570 (-)	NCBI

RefSeq Acc Id:

XM_063262256 ⟹ XP_063118326

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,786,053 - 123,905,585 (-)	NCBI

RefSeq Acc Id:

XM_063262257 ⟹ XP_063118327

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,789,294 - 123,905,585 (-)	NCBI

RefSeq Acc Id:

XM_063262258 ⟹ XP_063118328

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,775,269 - 123,847,661 (-)	NCBI

RefSeq Acc Id:

XM_063262259 ⟹ XP_063118329

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,775,269 - 123,835,260 (-)	NCBI

RefSeq Acc Id:

XM_063262260 ⟹ XP_063118330

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,817,044 - 123,905,585 (-)	NCBI

RefSeq Acc Id:

XR_010052132

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	123,802,116 - 123,905,585 (-)	NCBI


Protein RefSeqs	NP_001003402	(Get FASTA)	NCBI Sequence Viewer
	XP_063118318	(Get FASTA)	NCBI Sequence Viewer
	XP_063118319	(Get FASTA)	NCBI Sequence Viewer
	XP_063118320	(Get FASTA)	NCBI Sequence Viewer
	XP_063118321	(Get FASTA)	NCBI Sequence Viewer
	XP_063118322	(Get FASTA)	NCBI Sequence Viewer
	XP_063118323	(Get FASTA)	NCBI Sequence Viewer
	XP_063118324	(Get FASTA)	NCBI Sequence Viewer
	XP_063118325	(Get FASTA)	NCBI Sequence Viewer
	XP_063118326	(Get FASTA)	NCBI Sequence Viewer
	XP_063118327	(Get FASTA)	NCBI Sequence Viewer
	XP_063118328	(Get FASTA)	NCBI Sequence Viewer
	XP_063118329	(Get FASTA)	NCBI Sequence Viewer
	XP_063118330	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAS01608	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000054411
	ENSRNOP00000093290
GenBank Protein	Q6ED65	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001003402 ⟸ NM_001003402

- UniProtKB:

Q6ED65 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MAARSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFYRGHSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLVSVGLDS
KNAVCVWDWKRGKMLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIKFWSLCGNALTPKRGVFGKTGDLQTILCLACARDELTYSGALNGDIYVWKGINLIRTIQGAHTAGIFSMNACEEGFATGGRD
GCIRLWDLTFKPITVIDLRETEQGYKGLSVRSVCWRGDHILVGTQDSEIFEIVVHERNKPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNMDEPIRCAAVNADGVHLALG
MKDGSLTVLRVRDMTEVVHIKDRKEAIHELKYSPDGTYLAVGCNDSSVDIYGVAQRYKKVGECVGSLSFITHLDWSSDSKYLQTNDGSGKRLLYKMPGGKEVTSKEEVKGMHWASWTCVAGLEVNGIW
PKYSDINDINSVDGNYVGQVLVTADDYGVVKLFRYPCLRKGAKFRKYIGHSAHVTNVRWSHDYQWVISIGGADHSVFQWKFIPERKLKDALHIAPQESLTESNSDESDSDLSDVPELDSEIEQETQLT
YHRQVYKEDLPQLKEQCKEKQKSATSKRRERAPGNSIRLHFIHGYRGYDCRSNLFYTQIGEIVYHVAAVGVIYNRQQNTQRFYLGHDDDILCLAIHPLKDYVATGQVGRDPSIHVWDTETIKPLSILK
GYHQYGICAVDFSADGKRLASVGIDDSHTIVLWDWKKGEKLSVARGSKDKIFVVKMNPYVPDKLITAGIKHMKFWRRAGGGLIGRKGYVGTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIWRDVFLV
KTVKAHDGPVFSMHALEKGFVTGGKDGVVALWDDSFERCLKTYAIKRADLAPGSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEVDKSGPVTLLVQGHMEGEVWGLATHPYLPICATVSDDKTLRI
WDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDLVSFHHRKDVISDIQFSPGSGKYLAVASHDSFVDIYNVTSSKRVGVCKGATSYITHIDWDSRGKLLQVNTGAKEQLFF
EAPRGKKQTIPSVEVEKISWATWTSVLGLCCEGIWPIIGEVTDVTASCLTSDKMVLATGDDLGFVKLFRYPAKGKFGKFKKYVAHSTHVTNVRWTYDDSMLVTLGGADMSLMVWTSEVERHREKKNCD
SEESDTDSEEDGGYDSDVTRENEISYTIRALSTNIRPMFGVKPHLQQKEPSVDERQGVVRGSRPPVSRAPPQPEKLQSNNVGKKKRPIEDLVLELAFGYRGRDCRNNVHYLNDGDDIIYHTASVGILH
NVATGTQSFYQEHNDDILCLTVNQHPKFINIVATGQVGDSADMSATAPSVHIWDAVNKQTLSILRCSHSKGVCSVSFSATGKLLLSVGLDPEHTVTIWRWQEGAKIASRGGHNQRIFVAEFRPDSDTQ
FVSVGIKHVKFWTLAGRALLSKKGLLSTLEDARMQTMLAVAFGANNLTFTGTISGDVCVWKDHILCRVVARAHNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQVTDCV
RSVCRGKGKILVGTRNSEIIEVGEKNAACNILVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKKRDRRCAIHDIR
FSPDSRYLAVGSSENSVDFYDLTLGPTLNRISYCKDIPSFVIQMDFSADSRHLQVSSGCYKRHVYEVPSGKHLVDHAAIDRITWATWTSILGDEVMGIWSRHAEKADVTCACVSHSGISLVTGDDFGM
VKLYDFPCPEKFAKHKRFLGHSPHVTNIRFTSGDRHVVSAGGDDCSLLVWKCVHTPH

hide sequence

Ensembl Acc Id:

ENSRNOP00000054411 ⟸ ENSRNOT00000057601

Ensembl Acc Id:

ENSRNOP00000093290 ⟸ ENSRNOT00000096031

Ensembl Acc Id:

ENSRNOP00000096447 ⟸ ENSRNOT00000114559

RefSeq Acc Id:	XP_063118321 ⟸ XM_063262251
- Peptide Label:	isoform X4
- UniProtKB:	Q6ED65 (UniProtKB/Swiss-Prot)

Protein Domains

Anaphase-promoting complex subunit 4-like WD40

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6ED65-F1-model_v2	AlphaFold	Q6ED65	1-1977	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13694771

Promoter ID:

EPDNEW_R5295

Type:

single initiation site

Name:

Eml5_1

Description:

echinoderm microtubule associated protein like 5

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	122,898,031 - 122,898,091	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-36533	BioCyc
Ensembl Genes	ENSRNOG00000004207	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000057601	ENTREZGENE
	ENSRNOT00000096031	ENTREZGENE
Gene3D-CATH	2.130.10.10	UniProtKB/Swiss-Prot
InterPro	Apc4_WD40_dom	UniProtKB/Swiss-Prot
	HELP	UniProtKB/Swiss-Prot
	Quinoprotein_ADH-like_supfam	UniProtKB/Swiss-Prot
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/Swiss-Prot
	WD40_repeat	UniProtKB/Swiss-Prot
	WD40_repeat_CS	UniProtKB/Swiss-Prot
	WD40_repeat_dom_sf	UniProtKB/Swiss-Prot
	WD_repeat_EMAP	UniProtKB/Swiss-Prot
NCBI Gene	444982	ENTREZGENE
PANTHER	ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 5	UniProtKB/Swiss-Prot
	WD-40 REPEAT PROTEIN	UniProtKB/Swiss-Prot
Pfam	ANAPC4_WD40	UniProtKB/Swiss-Prot
	HELP	UniProtKB/Swiss-Prot
	WD40	UniProtKB/Swiss-Prot
PhenoGen	Eml5	PhenoGen
PROSITE	WD_REPEATS_1	UniProtKB/Swiss-Prot
	WD_REPEATS_2	UniProtKB/Swiss-Prot
	WD_REPEATS_REGION	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000004207	RatGTEx
SMART	WD40	UniProtKB/Swiss-Prot
Superfamily-SCOP	NHL repeat	UniProtKB/Swiss-Prot
	SSF50978	UniProtKB/Swiss-Prot
	SSF50998	UniProtKB/Swiss-Prot
	TolB, C-terminal domain	UniProtKB/Swiss-Prot
UniProt	A0A8I6GK80	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GLL5_RAT	UniProtKB/TrEMBL
	A6JEF3	ENTREZGENE, UniProtKB/TrEMBL
	EMAL5_RAT	UniProtKB/Swiss-Prot
	F1LSA8_RAT	UniProtKB/TrEMBL
	Q6ED65	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-12-04	Eml5	EMAP like 5	Eml5	echinoderm microtubule associated protein like 5	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-11-17	Eml5	echinoderm microtubule associated protein like 5			Symbol and Name status set to approved	1299863	APPROVED
2005-07-14	Eml5	echinoderm microtubule associated protein like 5			Symbol and Name status set to provisional	70820	PROVISIONAL

Note Type	Note	Reference
gene_domains	contains 11 WD40 domains, HELP domains, three hydrophobic stretches, a dimerization domain and appears to be present as two tandem repeats of sea urchin EMAP protein	1304007
gene_expression	highly expressed in hippocampus, cerebellum and olfactory bulb; expressed in forebrain and hindbrain structures during embryonic development	1304007
gene_homology	homologous to EMAP protein of sea urchin embryos which associates with microtubules	1304007

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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