Eml5 (EMAP like 5) - Rat Genome Database

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Gene: Eml5 (EMAP like 5) Rattus norvegicus
Analyze
Symbol: Eml5
Name: EMAP like 5
RGD ID: 1303275
Description: Predicted to enable microtubule binding activity. Predicted to be located in cytoplasm and microtubule. Orthologous to human EML5 (EMAP like 5); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: echinoderm microtubule associated protein like 5; echinoderm microtubule-associated protein-like 5; EMAP-5; EMAP-like protein 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86123,775,269 - 123,905,585 (-)NCBIGRCr8
mRatBN7.26118,046,655 - 118,175,831 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6118,046,655 - 118,175,831 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6118,197,287 - 118,325,751 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06118,494,088 - 118,622,546 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06117,828,943 - 117,957,398 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06122,768,939 - 122,898,046 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6122,770,055 - 122,897,997 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06131,989,998 - 132,118,760 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46122,958,412 - 123,087,547 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16122,973,904 - 123,091,229 (-)NCBI
Celera6115,606,223 - 115,734,030 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
microtubule  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Eml5, a novel WD40 domain protein expressed in rat brain. O'Connor V, etal., Gene 2004 Jul 7;336(1):127-37.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:19056867   PMID:36307995  


Genomics

Comparative Map Data
Eml5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86123,775,269 - 123,905,585 (-)NCBIGRCr8
mRatBN7.26118,046,655 - 118,175,831 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6118,046,655 - 118,175,831 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6118,197,287 - 118,325,751 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06118,494,088 - 118,622,546 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06117,828,943 - 117,957,398 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06122,768,939 - 122,898,046 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6122,770,055 - 122,897,997 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06131,989,998 - 132,118,760 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46122,958,412 - 123,087,547 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16122,973,904 - 123,091,229 (-)NCBI
Celera6115,606,223 - 115,734,030 (-)NCBICelera
Cytogenetic Map6q32NCBI
EML5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381488,612,431 - 88,792,953 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1488,612,431 - 88,792,953 (-)EnsemblGRCh38hg38GRCh38
GRCh371489,078,775 - 89,259,297 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361488,150,954 - 88,328,910 (-)NCBINCBI36Build 36hg18NCBI36
Build 341488,150,956 - 88,328,910NCBI
Celera1469,126,811 - 69,307,471 (-)NCBICelera
Cytogenetic Map14q31.3NCBI
HuRef1469,251,426 - 69,434,464 (-)NCBIHuRef
CHM1_11489,019,033 - 89,196,906 (-)NCBICHM1_1
T2T-CHM13v2.01482,833,321 - 83,016,566 (-)NCBIT2T-CHM13v2.0
Eml5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391298,752,863 - 98,867,770 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1298,753,064 - 98,867,743 (-)EnsemblGRCm39 Ensembl
GRCm381298,786,604 - 98,901,511 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1298,786,805 - 98,901,484 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712100,024,814 - 100,139,694 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361299,187,654 - 99,302,534 (-)NCBIMGSCv36mm8
Celera12100,012,303 - 100,127,197 (-)NCBICelera
Cytogenetic Map12ENCBI
cM Map1249.88NCBI
Eml5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543811,226,458 - 11,353,129 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543811,225,910 - 11,366,996 (-)NCBIChiLan1.0ChiLan1.0
EML5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21589,762,137 - 89,942,940 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11488,978,644 - 89,159,447 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01469,233,075 - 69,416,483 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11488,590,141 - 88,772,323 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1488,590,141 - 88,774,705 (-)Ensemblpanpan1.1panPan2
EML5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1859,850,400 - 60,033,245 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl859,853,379 - 60,033,906 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha859,428,164 - 59,610,985 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0860,119,892 - 60,302,646 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl860,119,984 - 60,303,239 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1859,798,834 - 59,981,830 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0859,844,113 - 60,032,955 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0860,178,155 - 60,361,241 (-)NCBIUU_Cfam_GSD_1.0
Eml5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864015,828,780 - 16,010,646 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648816,062,766 - 16,240,188 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648816,061,132 - 16,240,182 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EML5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7110,512,079 - 110,705,441 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17110,511,937 - 110,705,452 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27117,009,391 - 117,173,408 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EML5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12466,249,880 - 66,451,844 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2466,253,225 - 66,451,463 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605353,608,870 - 53,799,753 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eml5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473413,530,532 - 13,732,868 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473413,530,116 - 13,733,022 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Eml5
603 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:115
Count of miRNA genes:101
Interacting mature miRNAs:105
Transcripts:ENSRNOT00000005978, ENSRNOT00000057601
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6116506292130245370Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1300076Glom8Glomerulus QTL 879e-09kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat

Markers in Region
RH131268  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26118,045,603 - 118,045,788 (+)MAPPERmRatBN7.2
Rnor_6.06122,769,004 - 122,769,188NCBIRnor6.0
Rnor_5.06131,990,335 - 131,990,519UniSTSRnor5.0
RGSC_v3.46122,958,477 - 122,958,661UniSTSRGSC3.4
Celera6115,605,172 - 115,605,356UniSTS
RH 3.4 Map6870.1UniSTS
Cytogenetic Map6q32UniSTS
RH137891  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26118,057,458 - 118,057,624 (+)MAPPERmRatBN7.2
Rnor_6.06122,780,859 - 122,781,024NCBIRnor6.0
Rnor_5.06132,002,190 - 132,002,355UniSTSRnor5.0
RGSC_v3.46122,970,332 - 122,970,497UniSTSRGSC3.4
Celera6115,617,027 - 115,617,192UniSTS
RH 3.4 Map6870.39UniSTS
Cytogenetic Map6q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 49 113 89 88 57 25 57 6 215 96 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001003402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003750213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC098929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC117104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY445136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC092620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000057601   ⟹   ENSRNOP00000054411
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6118,046,655 - 118,175,831 (-)Ensembl
Rnor_6.0 Ensembl6122,770,055 - 122,897,997 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096031   ⟹   ENSRNOP00000093290
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6118,046,655 - 118,175,831 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114559   ⟹   ENSRNOP00000096447
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6118,047,104 - 118,175,831 (-)Ensembl
RefSeq Acc Id: NM_001003402   ⟹   NP_001003402
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86123,776,368 - 123,905,538 (-)NCBI
mRatBN7.26118,046,655 - 118,175,831 (-)NCBI
Rnor_6.06122,770,055 - 122,897,997 (-)NCBI
Rnor_5.06131,989,998 - 132,118,760 (-)NCBI
Celera6115,606,223 - 115,734,030 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063262248   ⟹   XP_063118318
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86123,775,269 - 123,905,585 (-)NCBI
RefSeq Acc Id: XM_063262249   ⟹   XP_063118319
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86123,775,269 - 123,905,585 (-)NCBI
RefSeq Acc Id: XM_063262250   ⟹   XP_063118320
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86123,775,269 - 123,905,585 (-)NCBI
RefSeq Acc Id: XM_063262251   ⟹   XP_063118321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86123,775,269 - 123,905,585 (-)NCBI
RefSeq Acc Id: XM_063262252   ⟹   XP_063118322
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86123,777,747 - 123,905,585 (-)NCBI
RefSeq Acc Id: XM_063262253   ⟹   XP_063118323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86123,777,581 - 123,905,585 (-)NCBI
RefSeq Acc Id: XM_063262254   ⟹   XP_063118324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86123,783,422 - 123,905,585 (-)NCBI
RefSeq Acc Id: XM_063262255   ⟹   XP_063118325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86123,775,269 - 123,863,570 (-)NCBI
RefSeq Acc Id: XM_063262256   ⟹   XP_063118326
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86123,786,053 - 123,905,585 (-)NCBI
RefSeq Acc Id: XM_063262257   ⟹   XP_063118327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86123,789,294 - 123,905,585 (-)NCBI
RefSeq Acc Id: XM_063262258   ⟹   XP_063118328
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86123,775,269 - 123,847,661 (-)NCBI
RefSeq Acc Id: XM_063262259   ⟹   XP_063118329
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86123,775,269 - 123,835,260 (-)NCBI
RefSeq Acc Id: XM_063262260   ⟹   XP_063118330
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86123,817,044 - 123,905,585 (-)NCBI
RefSeq Acc Id: XR_010052132
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86123,802,116 - 123,905,585 (-)NCBI
RefSeq Acc Id: NP_001003402   ⟸   NM_001003402
- UniProtKB: Q6ED65 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000054411   ⟸   ENSRNOT00000057601
Ensembl Acc Id: ENSRNOP00000093290   ⟸   ENSRNOT00000096031
Ensembl Acc Id: ENSRNOP00000096447   ⟸   ENSRNOT00000114559
RefSeq Acc Id: XP_063118321   ⟸   XM_063262251
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063118319   ⟸   XM_063262249
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063118320   ⟸   XM_063262250
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063118318   ⟸   XM_063262248
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063118325   ⟸   XM_063262255
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063118328   ⟸   XM_063262258
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063118329   ⟸   XM_063262259
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063118323   ⟸   XM_063262253
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063118322   ⟸   XM_063262252
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063118324   ⟸   XM_063262254
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063118326   ⟸   XM_063262256
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063118327   ⟸   XM_063262257
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063118330   ⟸   XM_063262260
- Peptide Label: isoform X13
Protein Domains
Anaphase-promoting complex subunit 4-like WD40

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6ED65-F1-model_v2 AlphaFold Q6ED65 1-1977 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694771
Promoter ID:EPDNEW_R5295
Type:single initiation site
Name:Eml5_1
Description:echinoderm microtubule associated protein like 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06122,898,031 - 122,898,091EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303275 AgrOrtholog
BioCyc Gene G2FUF-36533 BioCyc
Ensembl Genes ENSRNOG00000004207 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000057601.6 UniProtKB/TrEMBL
  ENSRNOT00000096031.1 UniProtKB/TrEMBL
  ENSRNOT00000114559.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Apc4_WD40_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HELP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Quinoprotein_ADH-like_supfam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_repeat_EMAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 444982 ENTREZGENE
PANTHER CALMODULIN UniProtKB/TrEMBL
  ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD-40 REPEAT PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ANAPC4_WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HELP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Eml5 PhenoGen
PROSITE WD_REPEATS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000004207 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP NHL repeat UniProtKB/Swiss-Prot
  SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50998 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TolB, C-terminal domain UniProtKB/Swiss-Prot
UniProt A0A8I6GK80_RAT UniProtKB/TrEMBL
  A0A8I6GLL5_RAT UniProtKB/TrEMBL
  EMAL5_RAT UniProtKB/Swiss-Prot
  F1LSA8_RAT UniProtKB/TrEMBL
  Q6ED65 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-12-04 Eml5  EMAP like 5  Eml5  echinoderm microtubule associated protein like 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Eml5  echinoderm microtubule associated protein like 5      Symbol and Name status set to approved 1299863 APPROVED
2005-07-14 Eml5  echinoderm microtubule associated protein like 5      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains 11 WD40 domains, HELP domains, three hydrophobic stretches, a dimerization domain and appears to be present as two tandem repeats of sea urchin EMAP protein 1304007
gene_expression highly expressed in hippocampus, cerebellum and olfactory bulb; expressed in forebrain and hindbrain structures during embryonic development 1304007
gene_homology homologous to EMAP protein of sea urchin embryos which associates with microtubules 1304007