Esrrg (estrogen-related receptor gamma) - Rat Genome Database

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Gene: Esrrg (estrogen-related receptor gamma) Rattus norvegicus
Analyze
Symbol: Esrrg
Name: estrogen-related receptor gamma
RGD ID: 1303236
Description: Predicted to enable several functions, including AF-2 domain binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and estrogen response element binding activity. Predicted to be involved in positive regulation of cold-induced thermogenesis and positive regulation of transcription by RNA polymerase II. Predicted to be active in chromatin and nucleus. Orthologous to human ESRRG (estrogen related receptor gamma); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: errg; estrogen receptor-related protein 3; nuclear receptor subfamily 3 group B member 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813101,699,043 - 102,316,877 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl13101,889,706 - 102,316,877 (+)EnsemblGRCr8
mRatBN7.21399,167,656 - 99,788,016 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1399,564,669 - 99,783,397 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx13101,739,863 - 102,301,030 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013103,128,963 - 103,690,094 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013100,325,840 - 100,886,886 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.013106,063,799 - 106,683,353 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13106,463,368 - 106,683,436 (+)Ensemblrn6Rnor6.0
Rnor_5.013110,713,353 - 111,328,942 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.413103,794,661 - 104,405,301 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1398,720,991 - 99,277,811 (+)NCBICelera
RGSC_v3.113103,983,703 - 104,594,344 (+)NCBI
Cytogenetic Map13q26NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-di-tert-butylphenol  (ISO)
2-arachidonoylglycerol  (ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-chloro-m-cresol  (ISO)
4-ethylphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-isopropylphenol  (ISO)
4-tert-butylphenol  (ISO)
4-tert-Octylphenol  (ISO)
5,6,7,8-tetrahydro-2-naphthol  (ISO)
8-Br-cAMP  (ISO)
afimoxifene  (EXP,ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
arachidonyl-2'-chloroethylamide  (EXP,ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
Benzo[ghi]perylene  (ISO)
Benzyl parahydroxybenzoate  (ISO)
biochanin A  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Bisphenol Z  (ISO)
Butylbenzyl phthalate  (ISO)
Butylparaben  (ISO)
cadmium atom  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
daidzein  (ISO)
diarsenic trioxide  (ISO)
diethylstilbestrol  (ISO)
dimethyl sulfoxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
Ethyl salicylate  (ISO)
ethylparaben  (ISO)
fenthion  (ISO)
folic acid  (ISO)
furan  (EXP)
genistein  (ISO)
glyphosate  (EXP)
GSK 4716  (ISO)
inulin  (ISO)
lithium chloride  (ISO)
LY294002  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methyl salicylate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
nickel atom  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
p-tert-Amylphenol  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenol red  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
propylparaben  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
sodium arsenite  (ISO)
tamoxifen  (ISO)
tauroursodeoxycholic acid  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zalcitabine  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IBA)
nucleus  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Estrogen receptor-related receptor gamma has an exceptionally broad specificity of DNA sequence recognition. Razzaque MA, etal., Gene 2004 Oct 13;340(2):275-82.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Orphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesis. Villena JA, etal., Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1418-23. doi: 10.1073/pnas.0607696104. Epub 2007 Jan 17.
Additional References at PubMed
PMID:10428842   PMID:12715898   PMID:15149736   PMID:17079227   PMID:21911493   PMID:23404793   PMID:23836911   PMID:26404484   PMID:36481985  


Genomics

Comparative Map Data
Esrrg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813101,699,043 - 102,316,877 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl13101,889,706 - 102,316,877 (+)EnsemblGRCr8
mRatBN7.21399,167,656 - 99,788,016 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1399,564,669 - 99,783,397 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx13101,739,863 - 102,301,030 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013103,128,963 - 103,690,094 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013100,325,840 - 100,886,886 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.013106,063,799 - 106,683,353 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13106,463,368 - 106,683,436 (+)Ensemblrn6Rnor6.0
Rnor_5.013110,713,353 - 111,328,942 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.413103,794,661 - 104,405,301 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1398,720,991 - 99,277,811 (+)NCBICelera
RGSC_v3.113103,983,703 - 104,594,344 (+)NCBI
Cytogenetic Map13q26NCBI
ESRRG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381216,503,246 - 217,137,702 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1216,503,246 - 217,137,755 (-)Ensemblhg38GRCh38
GRCh371216,676,588 - 217,311,044 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361214,743,211 - 215,329,599 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341213,064,982 - 213,651,371NCBI
Celera1189,900,435 - 190,535,016 (-)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1187,351,966 - 187,986,618 (-)NCBIHuRef
CHM1_11217,949,719 - 218,583,931 (-)NCBICHM1_1
T2T-CHM13v2.01215,743,580 - 216,378,774 (-)NCBIT2T-CHM13v2.0
Esrrg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391187,340,707 - 187,947,082 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1187,340,988 - 187,947,082 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381187,608,510 - 188,214,885 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1187,608,791 - 188,214,885 (+)Ensemblmm10GRCm38
MGSCv371189,821,738 - 190,038,763 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361189,698,647 - 189,915,672 (+)NCBIMGSCv36mm8
Celera1194,923,141 - 195,141,266 (+)NCBICelera
Cytogenetic Map1H5- H6NCBI
cM Map191.83NCBI
Esrrg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554061,560,485 - 1,788,250 (+)Ensembl
ChiLan1.0NW_0049554061,260,240 - 1,784,652 (+)NCBIChiLan1.0ChiLan1.0
ESRRG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2132,304,329 - 32,901,855 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1132,266,717 - 32,859,746 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01192,074,260 - 192,667,610 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11196,929,197 - 197,508,064 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1196,929,197 - 197,153,195 (-)EnsemblpanPan2panpan1.1
ESRRG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13811,825,055 - 12,439,143 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3811,823,520 - 12,256,028 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3811,862,256 - 12,476,998 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03811,851,190 - 12,466,509 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3811,849,973 - 12,421,362 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13811,864,007 - 12,478,053 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03812,216,132 - 12,830,227 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03812,517,096 - 13,132,572 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Esrrg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934459,454,088 - 60,048,171 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366281,830,881 - 2,058,269 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366281,635,161 - 2,058,198 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ESRRG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl106,712,860 - 6,941,501 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1106,710,615 - 7,371,419 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2108,646,197 - 8,720,519 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ESRRG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12512,495,234 - 13,090,739 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2512,866,321 - 13,090,733 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605512,918,159 - 13,515,132 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Esrrg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624835812,742 - 1,015,767 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624835815,230 - 1,326,376 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Esrrg
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11065,910,634 - 66,336,566 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Esrrg
3075 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:236
Count of miRNA genes:140
Interacting mature miRNAs:188
Transcripts:ENSRNOT00000003489
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1383286150109350286Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat

Markers in Region
D13Rat47  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21399,258,249 - 99,258,417 (+)MAPPERmRatBN7.2
Rnor_6.013106,156,025 - 106,156,192NCBIRnor6.0
Rnor_5.013110,802,823 - 110,802,990UniSTSRnor5.0
RGSC_v3.413103,828,388 - 103,828,555UniSTSRGSC3.4
RGSC_v3.413103,828,387 - 103,828,555RGDRGSC3.4
Celera1398,754,181 - 98,754,348UniSTS
RGSC_v3.113104,017,431 - 104,017,598RGD
RH 3.4 Map13669.2RGD
RH 3.4 Map13669.2UniSTS
RH 2.0 Map13728.0RGD
FHH x ACI Map1357.9RGD
Cytogenetic Map13q26UniSTS
D13Rat49  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr813102,310,218 - 102,310,357 (+)Marker Load Pipeline
mRatBN7.21399,778,880 - 99,779,019 (+)MAPPERmRatBN7.2
Rnor_6.013106,676,710 - 106,676,848NCBIRnor6.0
Rnor_5.013111,322,467 - 111,322,605UniSTSRnor5.0
RGSC_v3.413104,400,047 - 104,400,321RGDRGSC3.4
RGSC_v3.413104,400,153 - 104,400,291UniSTSRGSC3.4
Celera1399,273,152 - 99,273,290UniSTS
RGSC_v3.113104,589,196 - 104,589,334RGD
RH 3.4 Map13682.5RGD
RH 3.4 Map13682.5UniSTS
RH 2.0 Map13730.3RGD
FHH x ACI Map1358.79RGD
Cytogenetic Map13q26UniSTS
D13Got95  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21399,438,205 - 99,438,312 (+)MAPPERmRatBN7.2
Rnor_6.013106,338,935 - 106,339,041NCBIRnor6.0
Rnor_5.013110,985,046 - 110,985,152UniSTSRnor5.0
RGSC_v3.413104,009,971 - 104,010,078RGDRGSC3.4
RGSC_v3.413104,009,972 - 104,010,078UniSTSRGSC3.4
Celera1398,933,677 - 98,933,783UniSTS
RGSC_v3.113104,199,015 - 104,199,121RGD
RH 3.4 Map13682.6UniSTS
RH 3.4 Map13682.6RGD
RH 2.0 Map13728.8RGD
Cytogenetic Map13q26UniSTS
D13Got94  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21399,399,358 - 99,399,487 (+)MAPPERmRatBN7.2
Rnor_6.013106,300,059 - 106,300,187NCBIRnor6.0
Rnor_5.013110,946,170 - 110,946,298UniSTSRnor5.0
RGSC_v3.413103,970,590 - 103,970,719RGDRGSC3.4
RGSC_v3.413103,970,591 - 103,970,719UniSTSRGSC3.4
Celera1398,895,394 - 98,895,522UniSTS
RGSC_v3.113104,159,634 - 104,159,762RGD
RH 3.4 Map13683.9UniSTS
RH 3.4 Map13683.9RGD
RH 2.0 Map13747.5RGD
Cytogenetic Map13q26UniSTS
AU048237  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21399,248,165 - 99,248,325 (+)MAPPERmRatBN7.2
Rnor_6.013106,145,941 - 106,146,100NCBIRnor6.0
Rnor_5.013110,792,739 - 110,792,898UniSTSRnor5.0
RGSC_v3.413103,818,304 - 103,818,463UniSTSRGSC3.4
Celera1398,744,111 - 98,744,270UniSTS
Cytogenetic Map13q26UniSTS
BE108002  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21399,560,440 - 99,560,645 (+)MAPPERmRatBN7.2
Rnor_6.013106,459,171 - 106,459,375NCBIRnor6.0
Rnor_5.013111,105,529 - 111,105,733UniSTSRnor5.0
RGSC_v3.413104,133,489 - 104,133,693UniSTSRGSC3.4
Celera1399,055,270 - 99,055,474UniSTS
RH 3.4 Map13683.2UniSTS
Cytogenetic Map13q26UniSTS
UniSTS:495942  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21399,608,638 - 99,608,729 (+)MAPPERmRatBN7.2
Rnor_6.013106,507,415 - 106,507,505NCBIRnor6.0
Rnor_5.013111,153,773 - 111,153,863UniSTSRnor5.0
RGSC_v3.413104,182,190 - 104,182,280UniSTSRGSC3.4
Celera1399,103,440 - 99,103,530UniSTS
Cytogenetic Map13q26UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 64 164 91 90 59 81 59 6 357 179 11 137 95 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001401443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_203336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB126962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB126963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY341057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000003489   ⟹   ENSRNOP00000003489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl13102,096,025 - 102,316,877 (+)Ensembl
mRatBN7.2 Ensembl1399,564,669 - 99,783,397 (+)Ensembl
Rnor_6.0 Ensembl13106,463,368 - 106,683,436 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095864   ⟹   ENSRNOP00000087260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl13101,889,706 - 102,316,877 (+)Ensembl
mRatBN7.2 Ensembl1399,566,225 - 99,783,397 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000120836   ⟹   ENSRNOP00000098448
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl13102,097,465 - 102,316,877 (+)Ensembl
RefSeq Acc Id: NM_001401443   ⟹   NP_001388372
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813102,096,025 - 102,316,877 (+)NCBI
mRatBN7.21399,564,669 - 99,785,539 (+)NCBI
RefSeq Acc Id: NM_001415123   ⟹   NP_001402052
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,745,087 - 102,316,877 (+)NCBI
mRatBN7.21399,213,696 - 99,785,539 (+)NCBI
RefSeq Acc Id: NM_001415124   ⟹   NP_001402053
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,744,735 - 102,316,877 (+)NCBI
mRatBN7.21399,213,344 - 99,785,539 (+)NCBI
RefSeq Acc Id: NM_203336   ⟹   NP_976081
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,755,760 - 102,316,877 (+)NCBI
mRatBN7.21399,224,371 - 99,785,539 (+)NCBI
Rnor_6.013106,121,602 - 106,681,211 (+)NCBI
Rnor_5.013110,713,353 - 111,328,942 (+)NCBI
RGSC_v3.413103,794,661 - 104,405,301 (+)RGD
Celera1398,720,991 - 99,277,811 (+)RGD
Sequence:
RefSeq Acc Id: XM_017598866   ⟹   XP_017454355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,699,043 - 102,316,877 (+)NCBI
mRatBN7.21399,167,656 - 99,788,016 (+)NCBI
Rnor_6.013106,063,799 - 106,683,353 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039090940   ⟹   XP_038946868
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,699,043 - 102,316,877 (+)NCBI
mRatBN7.21399,167,656 - 99,788,016 (+)NCBI
RefSeq Acc Id: XM_039090941   ⟹   XP_038946869
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813102,012,809 - 102,316,877 (+)NCBI
mRatBN7.21399,485,359 - 99,788,016 (+)NCBI
RefSeq Acc Id: XM_063272508   ⟹   XP_063128578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,745,272 - 102,316,877 (+)NCBI
RefSeq Acc Id: XM_063272509   ⟹   XP_063128579
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,744,949 - 102,316,877 (+)NCBI
RefSeq Acc Id: XM_063272510   ⟹   XP_063128580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,699,043 - 102,316,877 (+)NCBI
RefSeq Acc Id: XM_063272511   ⟹   XP_063128581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,744,168 - 102,316,877 (+)NCBI
RefSeq Acc Id: NP_976081   ⟸   NM_203336
- Peptide Label: isoform 2
- UniProtKB: A6JGU0 (UniProtKB/TrEMBL),   A0A8I6A6X6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454355   ⟸   XM_017598866
- Peptide Label: isoform X1
- UniProtKB: A6JGU0 (UniProtKB/TrEMBL),   A0A8I6A6X6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003489   ⟸   ENSRNOT00000003489
RefSeq Acc Id: XP_038946868   ⟸   XM_039090940
- Peptide Label: isoform X1
- UniProtKB: A6JGU0 (UniProtKB/TrEMBL),   A0A8I6A6X6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946869   ⟸   XM_039090941
- Peptide Label: isoform X1
- UniProtKB: A6JGU0 (UniProtKB/TrEMBL),   A0A8I6A6X6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000087260   ⟸   ENSRNOT00000095864
RefSeq Acc Id: NP_001402053   ⟸   NM_001415124
- Peptide Label: isoform 2
- UniProtKB: A6JGU0 (UniProtKB/TrEMBL),   A0A8I6A6X6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001402052   ⟸   NM_001415123
- Peptide Label: isoform 2
- UniProtKB: A6JGU0 (UniProtKB/TrEMBL),   A0A8I6A6X6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001388372   ⟸   NM_001401443
- Peptide Label: isoform 1
- UniProtKB: Q75T51 (UniProtKB/Swiss-Prot),   Q5QJE4 (UniProtKB/Swiss-Prot),   P62510 (UniProtKB/Swiss-Prot),   Q75T52 (UniProtKB/Swiss-Prot),   A6JGT8 (UniProtKB/TrEMBL),   A0A8I6A6X6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128580   ⟸   XM_063272510
- Peptide Label: isoform X1
- UniProtKB: A6JGU0 (UniProtKB/TrEMBL),   A0A8I6A6X6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128581   ⟸   XM_063272511
- Peptide Label: isoform X1
- UniProtKB: A6JGU0 (UniProtKB/TrEMBL),   A0A8I6A6X6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128579   ⟸   XM_063272509
- Peptide Label: isoform X1
- UniProtKB: A6JGU0 (UniProtKB/TrEMBL),   A0A8I6A6X6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128578   ⟸   XM_063272508
- Peptide Label: isoform X1
- UniProtKB: A6JGU0 (UniProtKB/TrEMBL),   A0A8I6A6X6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000098448   ⟸   ENSRNOT00000120836
Protein Domains
NR LBD   Nuclear receptor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P62510-F1-model_v2 AlphaFold P62510 1-458 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699102
Promoter ID:EPDNEW_R9626
Type:single initiation site
Name:Esrrg_1
Description:estrogen-related receptor gamma
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013106,463,422 - 106,463,482EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303236 AgrOrtholog
BioCyc Gene G2FUF-16932 BioCyc
Ensembl Genes ENSRNOG00000002593 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000003489 ENTREZGENE
  ENSRNOT00000003489.5 UniProtKB/Swiss-Prot
  ENSRNOT00000095864 ENTREZGENE
Gene3D-CATH 1.10.565.10 UniProtKB/Swiss-Prot
  3.30.50.10 UniProtKB/Swiss-Prot
InterPro NHR-like_dom_sf UniProtKB/Swiss-Prot
  Nucl_hrmn_rcpt_lig-bd UniProtKB/Swiss-Prot
  Nuclear_hormone_rcpt_NR3 UniProtKB/Swiss-Prot
  Nuclear_hrmn_rcpt UniProtKB/Swiss-Prot
  Oest-rel_rcp UniProtKB/Swiss-Prot
  Oest_rcpt/oest-rel_rcp UniProtKB/Swiss-Prot
  Retinoic_acid_rcpt UniProtKB/Swiss-Prot
  Znf_hrmn_rcpt UniProtKB/Swiss-Prot
  Znf_NHR/GATA UniProtKB/Swiss-Prot
KEGG Report rno:360896 UniProtKB/Swiss-Prot
NCBI Gene 360896 ENTREZGENE
PANTHER KNIRPS-RELATED PROTEIN-RELATED UniProtKB/Swiss-Prot
Pfam Hormone_recep UniProtKB/Swiss-Prot
  zf-C4 UniProtKB/Swiss-Prot
PhenoGen Esrrg PhenoGen
PIRSF ER-like_NR UniProtKB/Swiss-Prot
  ERR1-2-3 UniProtKB/Swiss-Prot
PRINTS RETNOICACIDR UniProtKB/Swiss-Prot
  STRDHORMONER UniProtKB/Swiss-Prot
  STROIDFINGER UniProtKB/Swiss-Prot
PROSITE NR_LBD UniProtKB/Swiss-Prot
  NUCLEAR_REC_DBD_1 UniProtKB/Swiss-Prot
  NUCLEAR_REC_DBD_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000002593 RatGTEx
SMART HOLI UniProtKB/Swiss-Prot
  ZnF_C4 UniProtKB/Swiss-Prot
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot
  SSF48508 UniProtKB/Swiss-Prot
UniProt A0A8I6A6X6 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LAA2_RAT UniProtKB/TrEMBL
  A6JGT8 ENTREZGENE, UniProtKB/TrEMBL
  A6JGU0 ENTREZGENE, UniProtKB/TrEMBL
  ERR3_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5QJE4 ENTREZGENE
  Q75T51 ENTREZGENE
  Q75T52 ENTREZGENE
UniProt Secondary Q5QJE4 UniProtKB/Swiss-Prot
  Q75T51 UniProtKB/Swiss-Prot
  Q75T52 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-11-17 Esrrg  estrogen-related receptor gamma      Symbol updated 1299863 APPROVED
2005-07-14 errg  estrogen-related receptor gamma      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction recognizes inverted and direct DNA repeats with AGGTCA halfsites 1334481