Esrrg (estrogen-related receptor gamma) - Rat Genome Database

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Gene: Esrrg (estrogen-related receptor gamma) Rattus norvegicus
Analyze
Symbol: Esrrg
Name: estrogen-related receptor gamma
RGD ID: 1303236
Description: Predicted to enable several functions, including AF-2 domain binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and estrogen response element binding activity. Predicted to be involved in positive regulation of cold-induced thermogenesis and positive regulation of transcription by RNA polymerase II. Predicted to be active in chromatin and nucleus. Orthologous to human ESRRG (estrogen related receptor gamma); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: errg; estrogen receptor-related protein 3; nuclear receptor subfamily 3 group B member 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813101,699,043 - 102,316,877 (+)NCBIGRCr8
mRatBN7.21399,167,656 - 99,788,016 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1399,564,669 - 99,783,397 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13101,739,863 - 102,301,030 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013103,128,963 - 103,690,094 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013100,325,840 - 100,886,886 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013106,063,799 - 106,683,353 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13106,463,368 - 106,683,436 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013110,713,353 - 111,328,942 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413103,794,661 - 104,405,301 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113103,983,703 - 104,594,344 (+)NCBI
Celera1398,720,991 - 99,277,811 (+)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
EsrrgRatgastrointestinal stromal tumor  ISOESRRG (Homo sapiens)8554872ClinVar Annotator: match by term: Gastrointestinal stromal tumorClinVarPMID:28492532
EsrrgRatLoeys-Dietz syndrome 4  ISOESRRG (Homo sapiens)8554872ClinVar Annotator: match by term: Loeys-Dietz syndrome 4ClinVarPMID:22772368 and PMID:28544325
EsrrgRatparathyroid carcinoma  ISOESRRG (Homo sapiens)8554872ClinVar Annotator: match by term: Parathyroid carcinomaClinVarPMID:28492532
EsrrgRatprimary ovarian insufficiency  ISOESRRG (Homo sapiens)8554872ClinVar Annotator: match by term: Premature ovarian insufficiencyClinVarPMID:25741868
EsrrgRatUsher syndrome  ISOESRRG (Homo sapiens)8554872ClinVar Annotator: match by term: Usher syndromeClinVarPMID:28041643
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
EsrrgRatFetal Growth Retardation  ISOESRRG (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:35220427

1 to 20 of 164 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
EsrrgRat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ESRRG mRNA]CTDPMID:31150632
EsrrgRat(1->4)-beta-D-glucan multiple interactionsISOEsrrg (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ESRRG mRNACTDPMID:36331819
EsrrgRat1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactionsISOESRRG (Homo sapiens)64804642 more ...CTDPMID:31127318
EsrrgRat1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane affects bindingISOESRRG (Homo sapiens)64804642 more ...CTDPMID:32278787
EsrrgRat1,1-dichloroethene decreases expressionISOEsrrg (Mus musculus)6480464vinylidene chloride results in decreased expression of ESRRG mRNACTDPMID:26682919
EsrrgRat1,2-dichloroethane decreases expressionISOEsrrg (Mus musculus)6480464ethylene dichloride results in decreased expression of ESRRG mRNACTDPMID:28960355
EsrrgRat17beta-estradiol affects bindingISOESRRG (Homo sapiens)6480464Estradiol binds to ESRRG proteinCTDPMID:22935422
EsrrgRat17beta-estradiol decreases expressionISOEsrrg (Mus musculus)6480464Estradiol results in decreased expression of ESRRG mRNACTDPMID:39298647
EsrrgRat17beta-estradiol increases expressionISOEsrrg (Mus musculus)6480464Estradiol results in increased expression of ESRRG mRNACTDPMID:30196065
EsrrgRat17beta-estradiol multiple interactionsEXP 6480464[bisphenol A co-treated with Estradiol] results in decreased expression of ESRRG mRNACTDPMID:26496021
EsrrgRat17beta-estradiol increases expressionISOESRRG (Homo sapiens)6480464Estradiol results in increased expression of ESRRG mRNACTDPMID:25878060
EsrrgRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOEsrrg (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of ESRRG mRNACTDPMID:24058054
EsrrgRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of ESRRG mRNACTDPMID:32109520
EsrrgRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOEsrrg (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of ESRRG mRNACTDPMID:26377647 and PMID:28922406
EsrrgRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOEsrrg (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of ESRRG mRNACTDPMID:26290441 and PMID:37172768
EsrrgRat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of ESRRG mRNACTDPMID:22298810
EsrrgRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOEsrrg (Mus musculus)6480464[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of ESRRG mRNA and Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ESRRG promoter]CTDPMID:16214954 and PMID:19654925
EsrrgRat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
EsrrgRat2,4-di-tert-butylphenol increases activityISOESRRG (Homo sapiens)64804642 and 4-di-tert-butylphenol results in increased activity of ESRRG proteinCTDPMID:31127318
EsrrgRat2-arachidonoylglycerol increases abundanceISOEsrrg (Mus musculus)6480464ESRRG protein results in increased abundance of glyceryl 2-arachidonateCTDPMID:31912162

1 to 20 of 164 rows

Biological Process
1 to 17 of 17 rows

  
Object Symbol
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Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
EsrrgRatnuclear receptor-mediated steroid hormone signaling pathway involved_inIEAGO:00037071600115GO_REF:0000108GOCGO_REF:0000108
EsrrgRatpositive regulation of cold-induced thermogenesis involved_inISSUniProtKB:P6250913673809PMID:17229846YuBioLab 
EsrrgRatpositive regulation of cold-induced thermogenesis involved_inIEAUniProtKB:P62509 and ensembl:ENSMUSP000000279061600115GO_REF:0000107EnsemblGO_REF:0000107
EsrrgRatpositive regulation of cold-induced thermogenesis involved_inISOEsrrg (Mus musculus)1624291 PMID:17229846RGDPMID:17229846
EsrrgRatpositive regulation of DNA-templated transcription involved_inISOEsrrg (Mus musculus)1624291 PMID:12715898RGDPMID:12715898
EsrrgRatpositive regulation of DNA-templated transcription involved_inIEAUniProtKB:P62509 and ensembl:ENSMUSP000000279061600115GO_REF:0000107EnsemblGO_REF:0000107
EsrrgRatpositive regulation of nucleobase-containing compound metabolic process involved_inIEAARBA:ARBA000281731600115GO_REF:0000117UniProtGO_REF:0000117
EsrrgRatpositive regulation of transcription by RNA polymerase II involved_inISOEsrrg (Mus musculus)1624291 PMID:10428842 and PMID:15149736RGDPMID:10428842 and PMID:15149736
EsrrgRatpositive regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:P62509 and ensembl:ENSMUSP000000279061600115GO_REF:0000107EnsemblGO_REF:0000107
EsrrgRatpositive regulation of transcription by RNA polymerase II involved_inISSUniProtKB:P625091600115GO_REF:0000024UniProtGO_REF:0000024
EsrrgRatregulation of DNA-templated transcription involved_inIEAInterPro:IPR001628 more ...1600115GO_REF:0000002InterProGO_REF:0000002
EsrrgRatregulation of DNA-templated transcription involved_inIEAUniProtKB:P62508 and ensembl:ENSP000003861711600115GO_REF:0000107EnsemblGO_REF:0000107
EsrrgRatregulation of DNA-templated transcription involved_inISOESRRG (Homo sapiens)1624291 PMID:23836911RGDPMID:23836911
EsrrgRatregulation of DNA-templated transcription involved_inISSUniProtKB:P625081600115GO_REF:0000024UniProtGO_REF:0000024
EsrrgRatregulation of macromolecule biosynthetic process involved_inIEAARBA:ARBA000274011600115GO_REF:0000117UniProtGO_REF:0000117
EsrrgRatregulation of transcription by RNA polymerase II involved_inIBAFB:FBgn0035849 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
EsrrgRatretinoic acid receptor signaling pathway involved_inIEAInterPro:IPR0030781600115GO_REF:0000002InterProGO_REF:0000002
1 to 17 of 17 rows

Cellular Component

  
Object Symbol
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Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
EsrrgRatchromatin is_active_inIBAPANTHER:PTN002377694 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
EsrrgRatnucleus located_inIEAInterPro:IPR003078 more ...1600115GO_REF:0000002InterProGO_REF:0000002
EsrrgRatnucleus is_active_inIBAFB:FBgn0264562 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
EsrrgRatnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
EsrrgRatnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function
1 to 20 of 26 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
EsrrgRatAF-2 domain binding enablesISSUniProtKB:P625091600115GO_REF:0000024UniProtGO_REF:0000024
EsrrgRatDNA binding enablesIEAUniProtKB-KW:KW-02381600115GO_REF:0000043UniProtGO_REF:0000043
EsrrgRatDNA binding enablesIEAInterPro:IPR003078 more ...1600115GO_REF:0000002InterProGO_REF:0000002
EsrrgRatDNA-binding transcription activator activity, RNA polymerase II-specific enablesIEAUniProtKB:P62509 and ensembl:ENSMUSP000000279061600115GO_REF:0000107EnsemblGO_REF:0000107
EsrrgRatDNA-binding transcription activator activity, RNA polymerase II-specific enablesISOEsrrg (Mus musculus)1624291 PMID:10428842 and PMID:15149736RGDPMID:10428842 and PMID:15149736
EsrrgRatDNA-binding transcription factor activity enablesIEAInterPro:IPR0016281600115GO_REF:0000002InterProGO_REF:0000002
EsrrgRatestrogen response element binding enablesISOEsrrg (Mus musculus)1624291 PMID:10428842RGDPMID:10428842
EsrrgRatestrogen response element binding enablesIEAUniProtKB:P62509 and ensembl:ENSMUSP000000279061600115GO_REF:0000107EnsemblGO_REF:0000107
EsrrgRatestrogen response element binding enablesIBAMGI:1347056 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
EsrrgRatidentical protein binding enablesISOESRRG (Homo sapiens) and UniProtKB:P62508-31624291UniProtKB:P62508-3 and PMID:32296183RGDPMID:32296183
EsrrgRatmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
EsrrgRatnuclear receptor activity enablesIEAInterPro:IPR0030781600115GO_REF:0000002InterProGO_REF:0000002
EsrrgRatnuclear receptor activity enablesIBAFB:FBgn0264562 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
EsrrgRatnuclear steroid receptor activity enablesIEAInterPro:IPR024178 and InterPro:IPR0272891600115GO_REF:0000002InterProGO_REF:0000002
EsrrgRatprotein binding enablesISOESRRG (Homo sapiens) and UniProtKB:P62508-31624291UniProtKB:A0MZ66-4 more ...RGDPMID:32296183 and PMID:38225382
EsrrgRatprotein binding enablesISOEsrrg (Mus musculus)1624291UniProtKB:Q61026 more ...RGDPMID:10428842 and PMID:19690166
EsrrgRatprotein binding enablesISOESRRG (Homo sapiens)1624291UniProtKB:A0MZ66 more ...RGDPMID:10428842 more ...
EsrrgRatRNA polymerase II transcription regulatory region sequence-specific DNA binding enablesISOEsrrg (Mus musculus)1624291 PMID:15149736RGDPMID:15149736
EsrrgRatRNA polymerase II transcription regulatory region sequence-specific DNA binding enablesIEAUniProtKB:P62509 and ensembl:ENSMUSP000000279061600115GO_REF:0000107EnsemblGO_REF:0000107
EsrrgRatsequence-specific DNA binding enablesIEAInterPro:IPR0016281600115GO_REF:0000002InterProGO_REF:0000002
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Estrogen receptor-related receptor gamma has an exceptionally broad specificity of DNA sequence recognition. Razzaque MA, etal., Gene 2004 Oct 13;340(2):275-82.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Orphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesis. Villena JA, etal., Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1418-23. doi: 10.1073/pnas.0607696104. Epub 2007 Jan 17.
PMID:10428842   PMID:12715898   PMID:15149736   PMID:17079227   PMID:21911493   PMID:23404793   PMID:23836911   PMID:26404484   PMID:36481985  



Esrrg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813101,699,043 - 102,316,877 (+)NCBIGRCr8
mRatBN7.21399,167,656 - 99,788,016 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1399,564,669 - 99,783,397 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13101,739,863 - 102,301,030 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013103,128,963 - 103,690,094 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013100,325,840 - 100,886,886 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013106,063,799 - 106,683,353 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13106,463,368 - 106,683,436 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013110,713,353 - 111,328,942 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413103,794,661 - 104,405,301 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113103,983,703 - 104,594,344 (+)NCBI
Celera1398,720,991 - 99,277,811 (+)NCBICelera
Cytogenetic Map13q26NCBI
ESRRG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381216,503,246 - 217,137,702 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1216,503,246 - 217,137,755 (-)EnsemblGRCh38hg38GRCh38
GRCh371216,676,588 - 217,311,044 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361214,743,211 - 215,329,599 (-)NCBINCBI36Build 36hg18NCBI36
Build 341213,064,982 - 213,651,371NCBI
Celera1189,900,435 - 190,535,016 (-)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1187,351,966 - 187,986,618 (-)NCBIHuRef
CHM1_11217,949,719 - 218,583,931 (-)NCBICHM1_1
T2T-CHM13v2.01215,743,580 - 216,378,774 (-)NCBIT2T-CHM13v2.0
Esrrg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391187,340,707 - 187,947,082 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1187,340,988 - 187,947,082 (+)EnsemblGRCm39 Ensembl
GRCm381187,608,510 - 188,214,885 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1187,608,791 - 188,214,885 (+)EnsemblGRCm38mm10GRCm38
MGSCv371189,821,738 - 190,038,763 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361189,698,647 - 189,915,672 (+)NCBIMGSCv36mm8
Celera1194,923,141 - 195,141,266 (+)NCBICelera
Cytogenetic Map1H5- H6NCBI
cM Map191.83NCBI
Esrrg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554061,560,485 - 1,788,250 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554061,260,240 - 1,784,652 (+)NCBIChiLan1.0ChiLan1.0
ESRRG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2132,304,329 - 32,901,855 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1132,266,717 - 32,859,746 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01192,074,260 - 192,667,610 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11196,929,197 - 197,508,064 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1196,929,197 - 197,153,195 (-)Ensemblpanpan1.1panPan2
ESRRG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13811,825,055 - 12,439,143 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3811,823,520 - 12,256,028 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3811,862,256 - 12,476,998 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03811,851,190 - 12,466,509 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3811,849,973 - 12,421,362 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13811,864,007 - 12,478,053 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03812,216,132 - 12,830,227 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03812,517,096 - 13,132,572 (-)NCBIUU_Cfam_GSD_1.0
Esrrg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934459,454,088 - 60,048,171 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366281,830,881 - 2,058,269 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366281,635,161 - 2,058,198 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ESRRG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl106,712,860 - 6,941,501 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1106,710,615 - 7,371,419 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2108,646,197 - 8,720,519 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ESRRG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12512,495,234 - 13,090,739 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2512,866,321 - 13,090,733 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605512,918,159 - 13,515,132 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Esrrg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624835812,742 - 1,015,767 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624835815,230 - 1,326,376 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Esrrg
3443 total Variants

Predicted Target Of
Summary Value
Count of predictions:236
Count of miRNA genes:140
Interacting mature miRNAs:188
Transcripts:ENSRNOT00000003489
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 11 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1366451204106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat

1 to 10 of 11 rows
D13Rat47  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21399,258,249 - 99,258,417 (+)MAPPERmRatBN7.2
Rnor_6.013106,156,025 - 106,156,192NCBIRnor6.0
Rnor_5.013110,802,823 - 110,802,990UniSTSRnor5.0
RGSC_v3.413103,828,388 - 103,828,555UniSTSRGSC3.4
RGSC_v3.413103,828,387 - 103,828,555RGDRGSC3.4
RGSC_v3.113104,017,431 - 104,017,598RGD
Celera1398,754,181 - 98,754,348UniSTS
RH 3.4 Map13669.2RGD
RH 3.4 Map13669.2UniSTS
RH 2.0 Map13728.0RGD
FHH x ACI Map1357.9RGD
Cytogenetic Map13q26UniSTS
D13Rat49  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr813102,310,218 - 102,310,357 (+)Marker Load Pipeline
mRatBN7.21399,778,880 - 99,779,019 (+)MAPPERmRatBN7.2
Rnor_6.013106,676,710 - 106,676,848NCBIRnor6.0
Rnor_5.013111,322,467 - 111,322,605UniSTSRnor5.0
RGSC_v3.413104,400,047 - 104,400,321RGDRGSC3.4
RGSC_v3.413104,400,153 - 104,400,291UniSTSRGSC3.4
RGSC_v3.113104,589,196 - 104,589,334RGD
Celera1399,273,152 - 99,273,290UniSTS
RH 3.4 Map13682.5RGD
RH 3.4 Map13682.5UniSTS
RH 2.0 Map13730.3RGD
FHH x ACI Map1358.79RGD
Cytogenetic Map13q26UniSTS
D13Got95  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21399,438,205 - 99,438,312 (+)MAPPERmRatBN7.2
Rnor_6.013106,338,935 - 106,339,041NCBIRnor6.0
Rnor_5.013110,985,046 - 110,985,152UniSTSRnor5.0
RGSC_v3.413104,009,971 - 104,010,078RGDRGSC3.4
RGSC_v3.413104,009,972 - 104,010,078UniSTSRGSC3.4
RGSC_v3.113104,199,015 - 104,199,121RGD
Celera1398,933,677 - 98,933,783UniSTS
RH 3.4 Map13682.6UniSTS
RH 3.4 Map13682.6RGD
RH 2.0 Map13728.8RGD
Cytogenetic Map13q26UniSTS
D13Got94  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21399,399,358 - 99,399,487 (+)MAPPERmRatBN7.2
Rnor_6.013106,300,059 - 106,300,187NCBIRnor6.0
Rnor_5.013110,946,170 - 110,946,298UniSTSRnor5.0
RGSC_v3.413103,970,590 - 103,970,719RGDRGSC3.4
RGSC_v3.413103,970,591 - 103,970,719UniSTSRGSC3.4
RGSC_v3.113104,159,634 - 104,159,762RGD
Celera1398,895,394 - 98,895,522UniSTS
RH 3.4 Map13683.9UniSTS
RH 3.4 Map13683.9RGD
RH 2.0 Map13747.5RGD
Cytogenetic Map13q26UniSTS
AU048237  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21399,248,165 - 99,248,325 (+)MAPPERmRatBN7.2
Rnor_6.013106,145,941 - 106,146,100NCBIRnor6.0
Rnor_5.013110,792,739 - 110,792,898UniSTSRnor5.0
RGSC_v3.413103,818,304 - 103,818,463UniSTSRGSC3.4
Celera1398,744,111 - 98,744,270UniSTS
Cytogenetic Map13q26UniSTS
BE108002  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21399,560,440 - 99,560,645 (+)MAPPERmRatBN7.2
Rnor_6.013106,459,171 - 106,459,375NCBIRnor6.0
Rnor_5.013111,105,529 - 111,105,733UniSTSRnor5.0
RGSC_v3.413104,133,489 - 104,133,693UniSTSRGSC3.4
Celera1399,055,270 - 99,055,474UniSTS
RH 3.4 Map13683.2UniSTS
Cytogenetic Map13q26UniSTS
UniSTS:495942  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21399,608,638 - 99,608,729 (+)MAPPERmRatBN7.2
Rnor_6.013106,507,415 - 106,507,505NCBIRnor6.0
Rnor_5.013111,153,773 - 111,153,863UniSTSRnor5.0
RGSC_v3.413104,182,190 - 104,182,280UniSTSRGSC3.4
Celera1399,103,440 - 99,103,530UniSTS
Cytogenetic Map13q26UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 20 of 20 rows
RefSeq Transcripts NM_001401443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_203336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB126962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB126963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY341057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 20 of 20 rows

Ensembl Acc Id: ENSRNOT00000003489   ⟹   ENSRNOP00000003489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1399,564,669 - 99,783,397 (+)Ensembl
Rnor_6.0 Ensembl13106,463,368 - 106,683,436 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095864   ⟹   ENSRNOP00000087260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1399,566,225 - 99,783,397 (+)Ensembl
RefSeq Acc Id: NM_001401443   ⟹   NP_001388372
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813102,096,025 - 102,316,877 (+)NCBI
mRatBN7.21399,564,669 - 99,785,539 (+)NCBI
RefSeq Acc Id: NM_001415123   ⟹   NP_001402052
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,745,087 - 102,316,877 (+)NCBI
mRatBN7.21399,213,696 - 99,785,539 (+)NCBI
RefSeq Acc Id: NM_001415124   ⟹   NP_001402053
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,744,735 - 102,316,877 (+)NCBI
mRatBN7.21399,213,344 - 99,785,539 (+)NCBI
RefSeq Acc Id: NM_203336   ⟹   NP_976081
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,755,760 - 102,316,877 (+)NCBI
mRatBN7.21399,224,371 - 99,785,539 (+)NCBI
Rnor_6.013106,121,602 - 106,681,211 (+)NCBI
Rnor_5.013110,713,353 - 111,328,942 (+)NCBI
RGSC_v3.413103,794,661 - 104,405,301 (+)RGD
Celera1398,720,991 - 99,277,811 (+)RGD
Sequence:
RefSeq Acc Id: XM_017598866   ⟹   XP_017454355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,699,043 - 102,316,877 (+)NCBI
mRatBN7.21399,167,656 - 99,788,016 (+)NCBI
Rnor_6.013106,063,799 - 106,683,353 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039090940   ⟹   XP_038946868
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,699,043 - 102,316,877 (+)NCBI
mRatBN7.21399,167,656 - 99,788,016 (+)NCBI
RefSeq Acc Id: XM_039090941   ⟹   XP_038946869
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813102,012,809 - 102,316,877 (+)NCBI
mRatBN7.21399,485,359 - 99,788,016 (+)NCBI
RefSeq Acc Id: XM_063272508   ⟹   XP_063128578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,745,272 - 102,316,877 (+)NCBI
RefSeq Acc Id: XM_063272509   ⟹   XP_063128579
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,744,949 - 102,316,877 (+)NCBI
RefSeq Acc Id: XM_063272510   ⟹   XP_063128580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,699,043 - 102,316,877 (+)NCBI
RefSeq Acc Id: XM_063272511   ⟹   XP_063128581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813101,744,168 - 102,316,877 (+)NCBI
1 to 5 of 13 rows
1 to 5 of 13 rows
RefSeq Acc Id: NP_976081   ⟸   NM_203336
- Peptide Label: isoform 2
- UniProtKB: A6JGU0 (UniProtKB/TrEMBL),   A0A8I6A6X6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454355   ⟸   XM_017598866
- Peptide Label: isoform X1
- UniProtKB: A6JGU0 (UniProtKB/TrEMBL),   A0A8I6A6X6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003489   ⟸   ENSRNOT00000003489
RefSeq Acc Id: XP_038946868   ⟸   XM_039090940
- Peptide Label: isoform X1
- UniProtKB: A6JGU0 (UniProtKB/TrEMBL),   A0A8I6A6X6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946869   ⟸   XM_039090941
- Peptide Label: isoform X1
- UniProtKB: A6JGU0 (UniProtKB/TrEMBL),   A0A8I6A6X6 (UniProtKB/TrEMBL)
NR LBD   Nuclear receptor

Name Modeler Protein Id AA Range Protein Structure
AF-P62510-F1-model_v2 AlphaFold P62510 1-458 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13699102
Promoter ID:EPDNEW_R9626
Type:single initiation site
Name:Esrrg_1
Description:estrogen-related receptor gamma
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013106,463,422 - 106,463,482EPDNEW


1 to 40 of 45 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-16932 BioCyc
Ensembl Genes ENSRNOG00000002593 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000003489 ENTREZGENE
  ENSRNOT00000003489.5 UniProtKB/Swiss-Prot
  ENSRNOT00000095864 ENTREZGENE
Gene3D-CATH 1.10.565.10 UniProtKB/Swiss-Prot
  3.30.50.10 UniProtKB/Swiss-Prot
InterPro NHR-like_dom_sf UniProtKB/Swiss-Prot
  Nucl_hrmn_rcpt_lig-bd UniProtKB/Swiss-Prot
  Nuclear_hormone_rcpt_NR3 UniProtKB/Swiss-Prot
  Nuclear_hrmn_rcpt UniProtKB/Swiss-Prot
  Oest-rel_rcp UniProtKB/Swiss-Prot
  Oest_rcpt/oest-rel_rcp UniProtKB/Swiss-Prot
  Retinoic_acid_rcpt UniProtKB/Swiss-Prot
  Znf_hrmn_rcpt UniProtKB/Swiss-Prot
  Znf_NHR/GATA UniProtKB/Swiss-Prot
KEGG Report rno:360896 UniProtKB/Swiss-Prot
NCBI Gene 360896 ENTREZGENE
PANTHER KNIRPS-RELATED PROTEIN-RELATED UniProtKB/Swiss-Prot
Pfam Hormone_recep UniProtKB/Swiss-Prot
  zf-C4 UniProtKB/Swiss-Prot
PhenoGen Esrrg PhenoGen
PIRSF ER-like_NR UniProtKB/Swiss-Prot
  ERR1-2-3 UniProtKB/Swiss-Prot
PRINTS RETNOICACIDR UniProtKB/Swiss-Prot
  STRDHORMONER UniProtKB/Swiss-Prot
  STROIDFINGER UniProtKB/Swiss-Prot
PROSITE NR_LBD UniProtKB/Swiss-Prot
  NUCLEAR_REC_DBD_1 UniProtKB/Swiss-Prot
  NUCLEAR_REC_DBD_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000002593 RatGTEx
SMART HOLI UniProtKB/Swiss-Prot
  ZnF_C4 UniProtKB/Swiss-Prot
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot
  SSF48508 UniProtKB/Swiss-Prot
UniProt A0A8I6A6X6 ENTREZGENE, UniProtKB/TrEMBL
  A6JGT8 ENTREZGENE, UniProtKB/TrEMBL
  A6JGU0 ENTREZGENE, UniProtKB/TrEMBL
  ERR3_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5QJE4 ENTREZGENE
1 to 40 of 45 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-11-17 Esrrg  estrogen-related receptor gamma      Symbol updated 1299863 APPROVED
2005-07-14 errg  estrogen-related receptor gamma      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_physical_interaction recognizes inverted and direct DNA repeats with AGGTCA halfsites 1334481