Ppic (peptidylprolyl isomerase C) - Rat Genome Database

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Gene: Ppic (peptidylprolyl isomerase C) Rattus norvegicus
Analyze
Symbol: Ppic
Name: peptidylprolyl isomerase C
RGD ID: 1303221
Description: Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be active in cytoplasm. Orthologous to human PPIC (peptidylprolyl isomerase C); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC93799; peptidyl-prolyl cis-trans isomerase C
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81849,040,690 - 49,053,296 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1849,040,692 - 49,053,466 (-)EnsemblGRCr8
mRatBN7.21846,842,410 - 46,855,016 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1846,842,409 - 46,855,017 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1848,900,407 - 48,912,990 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01849,604,751 - 49,617,347 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01847,406,327 - 47,418,910 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01848,372,039 - 48,384,645 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1848,372,041 - 48,384,645 (-)Ensemblrn6Rnor6.0
Rnor_5.01847,585,434 - 47,598,040 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41848,886,548 - 48,899,154 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1845,024,826 - 45,037,432 (-)NCBICelera
RGSC_v3.11848,924,172 - 48,936,777 (-)NCBI
Cytogenetic Map18q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
calcitriol  (ISO)
cannabidiol  (ISO)
chlorpyrifos  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cytarabine  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
eugenol  (EXP)
Evodiamine  (ISO)
flutamide  (EXP)
folic acid  (ISO)
furan  (EXP)
glycidol  (EXP)
indole-3-methanol  (EXP)
indometacin  (ISO)
isobutanol  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
methamphetamine  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
PhIP  (EXP)
pirinixic acid  (ISO)
prothioconazole  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
protein folding  (IBA,IEA)

Cellular Component
cytoplasm  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Native recombinant cyclophilins A, B, and C degrade DNA independently of peptidylprolyl cis-trans-isomerase activity. Potential roles of cyclophilins in apoptosis. Montague JW, etal., J Biol Chem 1997 Mar 7;272(10):6677-84.
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Cyclophilin C-associated protein and cyclophilin C mRNA are upregulated in penumbral neurons and microglia after focal cerebral ischemia. Shimizu T, etal., J Cereb Blood Flow Metab 2005 Jan 12;.
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:1652374   PMID:20676357   PMID:23376485   PMID:23533145  


Genomics

Comparative Map Data
Ppic
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81849,040,690 - 49,053,296 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1849,040,692 - 49,053,466 (-)EnsemblGRCr8
mRatBN7.21846,842,410 - 46,855,016 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1846,842,409 - 46,855,017 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1848,900,407 - 48,912,990 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01849,604,751 - 49,617,347 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01847,406,327 - 47,418,910 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01848,372,039 - 48,384,645 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1848,372,041 - 48,384,645 (-)Ensemblrn6Rnor6.0
Rnor_5.01847,585,434 - 47,598,040 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41848,886,548 - 48,899,154 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1845,024,826 - 45,037,432 (-)NCBICelera
RGSC_v3.11848,924,172 - 48,936,777 (-)NCBI
Cytogenetic Map18q11NCBI
PPIC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385123,023,250 - 123,036,725 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5123,022,052 - 123,036,725 (-)Ensemblhg38GRCh38
GRCh375122,358,945 - 122,372,420 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365122,386,977 - 122,400,324 (-)NCBIBuild 36Build 36hg18NCBI36
Build 345122,386,976 - 122,400,324NCBI
Celera5118,313,549 - 118,326,899 (-)NCBICelera
Cytogenetic Map5q23.2NCBI
HuRef5117,547,085 - 117,560,441 (-)NCBIHuRef
CHM1_15121,791,686 - 121,805,032 (-)NCBICHM1_1
T2T-CHM13v2.05123,539,800 - 123,553,272 (-)NCBIT2T-CHM13v2.0
Ppic
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391853,539,413 - 53,551,079 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1853,539,404 - 53,551,187 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381853,406,341 - 53,418,007 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1853,406,332 - 53,418,115 (-)Ensemblmm10GRCm38
MGSCv371853,565,995 - 53,577,661 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361853,531,710 - 53,543,376 (-)NCBIMGSCv36mm8
Celera1854,714,243 - 54,725,974 (-)NCBICelera
Cytogenetic Map18D1NCBI
cM Map1829.03NCBI
Ppic
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555211,138,779 - 1,143,356 (-)Ensembl
ChiLan1.0NW_0049555211,138,779 - 1,143,345 (-)NCBIChiLan1.0ChiLan1.0
PPIC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24118,310,584 - 118,324,206 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15116,464,247 - 116,477,625 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05118,415,061 - 118,428,438 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15124,195,133 - 124,208,527 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5124,195,133 - 124,208,527 (-)EnsemblpanPan2panpan1.1
PPIC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11112,882,676 - 12,893,337 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1112,883,113 - 12,889,427 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1111,664,158 - 11,676,350 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01113,588,849 - 13,601,068 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1113,589,286 - 13,601,063 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11112,328,586 - 12,340,940 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01112,147,497 - 12,159,701 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01112,777,661 - 12,790,143 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ppic
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213135,327,310 - 135,349,748 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365753,408,547 - 3,431,021 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365753,408,568 - 3,430,974 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPIC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2126,531,365 - 126,547,753 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12126,531,356 - 126,547,775 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22131,748,541 - 131,764,135 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPIC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12326,079,473 - 26,095,595 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2326,075,893 - 26,095,604 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603452,032,395 - 52,048,741 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppic
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477418,991,646 - 19,002,556 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477418,991,651 - 19,002,503 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ppic
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11578,340,801 - 78,353,391 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ppic
162 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:86
Count of miRNA genes:69
Interacting mature miRNAs:80
Transcripts:ENSRNOT00000023485
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182507112683910656Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)182201556261600538Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182349405785487725Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
1331736Bp227Blood pressure QTL 2272.791arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)184891705460064728Rat
631834Sach3Saccharin preference QTL 33.90.01consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)183857591983575919Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182682218671822186Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182682218671822186Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182682218671822186Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184562030686134022Rat
1331727Bp237Blood pressure QTL 2373.053arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050563968306Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182682218671822186Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184891573786134022Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184891573786134022Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182682218671822186Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182682218671822186Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183199089176990891Rat
1331770Bp234Blood pressure QTL 2343.807arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184562030686134022Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181206648285493247Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183161050585493247Rat
12880368Bw187Body weight QTL 1870.045body mass (VT:0001259)body weight (CMO:0000012)183337915878379158Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)184046238385462383Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18448264849482648Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)183199089176990891Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18154490981Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181206648285493247Rat
11565454Kidm59Kidney mass QTL 590.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)18706572852065728Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228086134022Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)18430735449307354Rat
12904069Cm123Cardiac mass QTL 1230.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)183337915878379158Rat
2301409Cm70Cardiac mass QTL 700.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)18706572852065728Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
12904070Cm124Cardiac mass QTL 1240.01heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)183337915878379158Rat
12904071Am18Aortic mass QTL 180.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)183337915878379158Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182682218671822186Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183152278376522783Rat
12904067Cm122Cardiac mass QTL 1220.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)183337915878379158Rat
12904716Am21Aortic mass QTL 210.005aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)18706572852065728Rat
2301417Bp319Blood pressure QTL 3190.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183337915878379158Rat
1331806Bp229Blood pressure QTL 2294.36484arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184891705460064728Rat
12904073Kidm71Kidney mass QTL 710.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)183337915878379158Rat
12904714Cm131Cardiac mass QTL 1310.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)18706572852065728Rat
12904715Cm132Cardiac mass QTL 1320.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)18706572852065728Rat
1331780Bp238Blood pressure QTL 2383.269arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184891705460064728Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183161050577371277Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183612162681121626Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)183199089176990891Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184891573786134022Rat
631509Sald2Serum aldosterone level QTL 22.9blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)182641582171415821Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183164450879484311Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181955353285493247Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181206648257066482Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)183199089176990891Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183161050572538878Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 148 91 90 59 28 59 6 292 128 11 127 81 92 31 10 10

Sequence


Ensembl Acc Id: ENSRNOT00000023485   ⟹   ENSRNOP00000023485
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1849,040,692 - 49,053,296 (-)Ensembl
mRatBN7.2 Ensembl1846,842,409 - 46,855,017 (-)Ensembl
Rnor_6.0 Ensembl1848,372,041 - 48,384,645 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112899   ⟹   ENSRNOP00000079353
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1849,040,692 - 49,053,466 (-)Ensembl
mRatBN7.2 Ensembl1846,842,420 - 46,854,999 (-)Ensembl
RefSeq Acc Id: NM_001004215   ⟹   NP_001004215
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81849,040,690 - 49,053,296 (-)NCBI
mRatBN7.21846,842,410 - 46,855,016 (-)NCBI
Rnor_6.01848,372,039 - 48,384,645 (-)NCBI
Rnor_5.01847,585,434 - 47,598,040 (-)NCBI
RGSC_v3.41848,886,548 - 48,899,154 (-)RGD
Celera1845,024,826 - 45,037,432 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001004215 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH78949 (Get FASTA)   NCBI Sequence Viewer  
  EDM14461 (Get FASTA)   NCBI Sequence Viewer  
  EDM14462 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000023485
  ENSRNOP00000023485.5
  ENSRNOP00000079353.2
RefSeq Acc Id: NP_001004215   ⟸   NM_001004215
- Peptide Label: precursor
- UniProtKB: Q6AYQ9 (UniProtKB/TrEMBL),   A0A8I5ZN96 (UniProtKB/TrEMBL),   F7FHM1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000023485   ⟸   ENSRNOT00000023485
Ensembl Acc Id: ENSRNOP00000079353   ⟸   ENSRNOT00000112899
Protein Domains
PPIase cyclophilin-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYQ9-F1-model_v2 AlphaFold Q6AYQ9 1-212 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700785
Promoter ID:EPDNEW_R11309
Type:initiation region
Name:Ppic_1
Description:peptidylprolyl isomerase C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01848,384,630 - 48,384,690EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303221 AgrOrtholog
BioCyc Gene G2FUF-7505 BioCyc
Ensembl Genes ENSRNOG00000017416 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000023485 ENTREZGENE
  ENSRNOT00000023485.6 UniProtKB/TrEMBL
  ENSRNOT00000112899.2 UniProtKB/TrEMBL
Gene3D-CATH 2.40.100.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7109986 IMAGE-MGC_LOAD
InterPro Cyclophilin-like_dom UniProtKB/TrEMBL
  Pep-Pro_Isoase_cyclophilin_CS UniProtKB/TrEMBL
  PPIase_cyclophilin UniProtKB/TrEMBL
KEGG Report rno:291463 UniProtKB/TrEMBL
MGC_CLONE MGC:93799 IMAGE-MGC_LOAD
NCBI Gene 291463 ENTREZGENE
PANTHER PEPTIDYL-PROLYL CIS-TRANS ISOMERASE UniProtKB/TrEMBL
  PEPTIDYL-PROLYL CIS-TRANS ISOMERASE C UniProtKB/TrEMBL
Pfam Pro_isomerase UniProtKB/TrEMBL
PhenoGen Ppic PhenoGen
PRINTS CSAPPISMRASE UniProtKB/TrEMBL
PROSITE CSA_PPIASE_1 UniProtKB/TrEMBL
  CSA_PPIASE_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017416 RatGTEx
Superfamily-SCOP SSF50891 UniProtKB/TrEMBL
UniProt A0A8I5ZN96 ENTREZGENE, UniProtKB/TrEMBL
  A6IX31_RAT UniProtKB/TrEMBL
  F7FHM1 ENTREZGENE, UniProtKB/TrEMBL
  Q6AYQ9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Ppic  peptidylprolyl isomerase C      Symbol and Name status set to approved 1299863 APPROVED
2005-07-14 Ppic  peptidylprolyl isomerase C      Symbol and Name status set to provisional 70820 PROVISIONAL