Ube4a (ubiquitination factor E4A) - Rat Genome Database

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Gene: Ube4a (ubiquitination factor E4A) Rattus norvegicus
Analyze
Symbol: Ube4a
Name: ubiquitination factor E4A
RGD ID: 1303173
Description: Predicted to enable ubiquitin-ubiquitin ligase activity. Predicted to be involved in ERAD pathway and protein polyubiquitination. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human UBE4A (ubiquitination factor E4A); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 1,3-dinitrobenzene; bisphenol A; Butylbenzyl phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ab2-232; RING-type E3 ubiquitin transferase E4 A; ubiquitin conjugation factor E4 A; ubiquitination factor E4A (UFD2 homolog, yeast); ubiquitination factor E4A, UFD2 homolog; ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8854,132,799 - 54,174,921 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl854,132,801 - 54,174,835 (-)EnsemblGRCr8
mRatBN7.2845,236,022 - 45,278,129 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl845,236,026 - 45,278,038 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx850,731,379 - 50,773,216 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0849,010,100 - 49,051,937 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0846,880,680 - 46,922,496 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0849,229,713 - 49,271,894 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl849,229,717 - 49,271,834 (-)Ensemblrn6Rnor6.0
Rnor_5.0847,847,865 - 47,889,725 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4847,879,266 - 47,918,955 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera844,820,845 - 44,860,533 (-)NCBICelera
RGSC_v3.1847,888,031 - 47,927,727 (-)NCBI
Cytogenetic Map8q22NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA,ISO)
nucleus  (IBA)
ubiquitin ligase complex  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Expression analysis of the gene encoding for the U-box-type ubiquitin ligase UBE4A in human tissues. Contino G, etal., Gene 2004 Mar 17;328:69-74.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:10811609   PMID:11435423   PMID:15489334   PMID:16103111  


Genomics

Comparative Map Data
Ube4a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8854,132,799 - 54,174,921 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl854,132,801 - 54,174,835 (-)EnsemblGRCr8
mRatBN7.2845,236,022 - 45,278,129 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl845,236,026 - 45,278,038 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx850,731,379 - 50,773,216 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0849,010,100 - 49,051,937 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0846,880,680 - 46,922,496 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0849,229,713 - 49,271,894 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl849,229,717 - 49,271,834 (-)Ensemblrn6Rnor6.0
Rnor_5.0847,847,865 - 47,889,725 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4847,879,266 - 47,918,955 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera844,820,845 - 44,860,533 (-)NCBICelera
RGSC_v3.1847,888,031 - 47,927,727 (-)NCBI
Cytogenetic Map8q22NCBI
UBE4A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811118,359,600 - 118,399,211 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11118,359,587 - 118,399,211 (+)Ensemblhg38GRCh38
GRCh3711118,230,315 - 118,269,926 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611117,735,512 - 117,775,136 (+)NCBIBuild 36Build 36hg18NCBI36
Build 3411117,735,511 - 117,775,134NCBI
Celera11115,388,170 - 115,427,789 (+)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11114,164,298 - 114,204,054 (+)NCBIHuRef
CHM1_111118,116,796 - 118,156,382 (+)NCBICHM1_1
T2T-CHM13v2.011118,375,859 - 118,415,462 (+)NCBIT2T-CHM13v2.0
Ube4a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39944,834,425 - 44,877,021 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl944,834,425 - 44,876,898 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38944,923,127 - 44,965,615 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl944,923,127 - 44,965,600 (-)Ensemblmm10GRCm38
MGSCv37944,731,210 - 44,773,683 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36944,684,066 - 44,716,520 (-)NCBIMGSCv36mm8
Celera942,188,425 - 42,230,712 (-)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map924.84NCBI
Ube4a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541219,516,691 - 19,553,773 (+)Ensembl
ChiLan1.0NW_00495541219,517,182 - 19,551,503 (+)NCBIChiLan1.0ChiLan1.0
UBE4A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29119,060,507 - 119,100,203 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111120,165,574 - 120,205,255 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011113,193,986 - 113,233,660 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111117,125,582 - 117,162,518 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11117,131,100 - 117,162,385 (+)EnsemblpanPan2panpan1.1
UBE4A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1515,338,279 - 15,375,722 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl515,341,141 - 15,370,294 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha515,389,033 - 15,426,486 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0515,280,409 - 15,318,046 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl515,280,447 - 15,317,969 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1515,418,864 - 15,456,318 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0515,322,601 - 15,359,769 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0515,363,227 - 15,400,919 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
UBE4A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl945,661,106 - 45,704,810 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1945,661,090 - 45,701,911 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2950,702,219 - 50,743,041 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UBE4A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11109,735,778 - 109,776,629 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1109,735,752 - 109,776,661 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604316,258,929 - 16,299,903 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ube4a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478413,754,234 - 13,792,616 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ube4a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1839,458,596 - 39,500,964 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ube4a
305 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:909
Count of miRNA genes:338
Interacting mature miRNAs:441
Transcripts:ENSRNOT00000021321
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83975280384752803Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83910625891341052Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81699464261994642Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83910625891341052Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)839106363103375781Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)81595227960952279Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)81296416557964165Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)85076395195763951Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83910625884106258Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)81296416557964165Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)85158969999045312Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)81038254055382540Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)839106363103375781Rat
5684993Bmd84Bone mineral density QTL 844.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)85158969958991895Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)84447792689477926Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81699464261994642Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)81038254055382540Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)839106258103375958Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)81296416557964165Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)81038254055382540Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83910625891341052Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)84754141992541419Rat
2302278Gluco36Glucose level QTL 364.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)83776085958991895Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)81038254055382540Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)83776085961459705Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)83546407171842899Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83910625884106258Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84961020468373388Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)83154366176543661Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)850763951107970527Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625884106258Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84961020494610204Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84444783789447837Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81799386262252873Rat
1331744Bp217Blood pressure QTL 2173.398arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625867378345Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83910625891341052Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)84924517894245178Rat
724540Uae8Urinary albumin excretion QTL 85urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)839106258103375958Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
631216Stl9Serum triglyceride level QTL 94.710.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)85076395167219641Rat
1359021Bp271Blood pressure QTL 2711.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)83412590255607752Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)84924517894245178Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)84447504389475043Rat

Markers in Region
RH128999  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2845,236,095 - 45,236,258 (+)MAPPERmRatBN7.2
Rnor_6.0849,229,787 - 49,229,949NCBIRnor6.0
Rnor_5.0847,847,939 - 47,848,101UniSTSRnor5.0
RGSC_v3.4847,879,338 - 47,879,500UniSTSRGSC3.4
Celera844,820,917 - 44,821,079UniSTS
RH 3.4 Map8449.3UniSTS
Cytogenetic Map8q22UniSTS
RH142941  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8854,135,316 - 54,135,488 (+)Marker Load Pipeline
mRatBN7.2845,238,539 - 45,238,712 (+)MAPPERmRatBN7.2
Rnor_6.0849,232,231 - 49,232,402NCBIRnor6.0
Rnor_5.0847,850,383 - 47,850,554UniSTSRnor5.0
RGSC_v3.4847,881,782 - 47,881,953UniSTSRGSC3.4
Celera844,823,361 - 44,823,532UniSTS
RH 3.4 Map8449.3UniSTS
Cytogenetic Map8q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000021321   ⟹   ENSRNOP00000021321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl854,132,801 - 54,174,835 (-)Ensembl
mRatBN7.2 Ensembl845,236,026 - 45,275,717 (-)Ensembl
Rnor_6.0 Ensembl849,229,717 - 49,269,411 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000085022   ⟹   ENSRNOP00000070856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl854,132,801 - 54,174,835 (-)Ensembl
mRatBN7.2 Ensembl845,236,026 - 45,275,717 (-)Ensembl
Rnor_6.0 Ensembl849,232,176 - 49,271,834 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093958   ⟹   ENSRNOP00000096076
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl854,136,772 - 54,168,022 (-)Ensembl
mRatBN7.2 Ensembl845,259,855 - 45,278,038 (-)Ensembl
RefSeq Acc Id: NM_207610   ⟹   NP_997493
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8854,132,801 - 54,174,835 (-)NCBI
mRatBN7.2845,236,024 - 45,278,062 (-)NCBI
Rnor_6.0849,229,715 - 49,269,405 (-)NCBI
Rnor_5.0847,847,865 - 47,889,725 (-)NCBI
RGSC_v3.4847,879,266 - 47,918,955 (-)RGD
Celera844,820,845 - 44,860,533 (-)RGD
Sequence:
RefSeq Acc Id: XM_006242938   ⟹   XP_006243000
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8854,132,799 - 54,174,921 (-)NCBI
mRatBN7.2845,236,022 - 45,278,129 (-)NCBI
Rnor_6.0849,229,713 - 49,271,894 (-)NCBI
Rnor_5.0847,847,865 - 47,889,725 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_997493 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243000 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH61761 (Get FASTA)   NCBI Sequence Viewer  
  AAP92599 (Get FASTA)   NCBI Sequence Viewer  
  EDL95342 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021321
  ENSRNOP00000096076
GenBank Protein Q6P7A2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_997493   ⟸   NM_207610
- UniProtKB: Q6P7A2 (UniProtKB/Swiss-Prot),   F1M9N5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243000   ⟸   XM_006242938
- Peptide Label: isoform X1
- UniProtKB: Q6P7A2 (UniProtKB/Swiss-Prot),   Q7TP51 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021321   ⟸   ENSRNOT00000021321
Ensembl Acc Id: ENSRNOP00000070856   ⟸   ENSRNOT00000085022
Ensembl Acc Id: ENSRNOP00000096076   ⟸   ENSRNOT00000093958
Protein Domains
U-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P7A2-F1-model_v2 AlphaFold Q6P7A2 1-1066 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695912
Promoter ID:EPDNEW_R6430
Type:initiation region
Name:Ube4a_1
Description:ubiquitination factor E4A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0849,271,799 - 49,271,859EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303173 AgrOrtholog
BioCyc Gene G2FUF-30692 BioCyc
Ensembl Genes ENSRNOG00000026833 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000021321 ENTREZGENE
  ENSRNOT00000093958 ENTREZGENE
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5621078 IMAGE-MGC_LOAD
InterPro Ub_conjug_fac_E4_core UniProtKB/Swiss-Prot
  UBE4 UniProtKB/Swiss-Prot
  Ubox_domain UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
KEGG Report rno:315608 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72632 IMAGE-MGC_LOAD
NCBI Gene 315608 ENTREZGENE
PANTHER PTHR13931 UniProtKB/Swiss-Prot
  UBIQUITIN CONJUGATION FACTOR E4 A UniProtKB/Swiss-Prot
Pfam U-box UniProtKB/Swiss-Prot
  Ufd2P_core UniProtKB/Swiss-Prot
PhenoGen Ube4a PhenoGen
PROSITE U_BOX UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000026833 RatGTEx
SMART Ubox UniProtKB/Swiss-Prot
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot
UniProt A0A0G2JZ00_RAT UniProtKB/TrEMBL
  A0A8I6AN47_RAT UniProtKB/TrEMBL
  F1M9N5 ENTREZGENE, UniProtKB/TrEMBL
  Q6P7A2 ENTREZGENE
  Q7TP51 ENTREZGENE, UniProtKB/TrEMBL
  UBE4A_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-01 Ube4a  ubiquitination factor E4A  Ube4a  ubiquitination factor E4A (UFD2 homolog, yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-25 Ube4a  ubiquitination factor E4A (UFD2 homolog, yeast)  Ube4a  ubiquitination factor E4A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-15 Ube4a  ubiquitination factor E4A  Ube4a  ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Ube4a  ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)    ubiquitin conjugation factor E4 A  Name updated 1299863 APPROVED
2005-07-14 Ube4a  ubiquitin conjugation factor E4 A      Symbol and Name status set to provisional 70820 PROVISIONAL