Predicted to enable several functions, including adipokinetic hormone receptor activity; adiponectin binding activity; and identical protein binding activity. Involved in cytokine-mediated signaling pathway; negative regulation of cell growth; and positive regulation of signal transduction. Predicted to be active in plasma membrane. Biomarker of end stage renal disease; hyperglycemia; hyperinsulinism; and obesity. Human ortholog(s) of this gene implicated in breast cancer; macular degeneration; and prostate adenocarcinoma. Orthologous to human ADIPOR1 (adiponectin receptor 1); PARTICIPATES IN adiponectin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-aminobenzamide; 9-cis,11-trans-octadecadienoic acid.
[osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOR1 protein and MRI-1867 inhibits the reaction [[osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOR1 protein]
ADIPOR1 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]] and ADIPOR1 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]]
[osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOR1 protein and MRI-1867 inhibits the reaction [[osteum co-treated with Palmitic Acid] results in decreased expression of ADIPOR1 protein]