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Gene: Kansl2 (KAT8 regulatory NSL complex subunit 2) Rattus norvegicus

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Symbol:

Kansl2

Name:

KAT8 regulatory NSL complex subunit 2

RGD ID:

1303127

Description:

Predicted to be involved in chromatin organization. Predicted to be located in several cellular components, including actin cytoskeleton; cytosol; and nucleoplasm. Predicted to be part of NSL complex. Predicted to be active in mitochondrion. Orthologous to human KANSL2 (KAT8 regulatory NSL complex subunit 2); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

hypothetical protein LOC300206; LOC103690317; MGC94200; non-specific lethal 2 homolog; NSL complex protein NSL2; RGD1303127; similar to hypothetical protein FLJ20436; uncharacterized protein C12orf41 homolog

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KANSL2 (KAT8 regulatory NSL complex subunit 2)	HGNC	Ensembl, HomoloGene, Inparanoid, Panther
Mus musculus (house mouse):	Kansl2 (KAT8 regulatory NSL complex subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Kansl2 (KAT8 regulatory NSL complex subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KANSL2 (KAT8 regulatory NSL complex subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KANSL2 (KAT8 regulatory NSL complex subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Kansl2 (KAT8 regulatory NSL complex subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KANSL2 (KAT8 regulatory NSL complex subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KANSL2 (KAT8 regulatory NSL complex subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Kansl2 (KAT8 regulatory NSL complex subunit 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	KANSL2 (KAT8 regulatory NSL complex subunit 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Kansl2 (KAT8 regulatory NSL complex subunit 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	dgt1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	kansl2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	kansl2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Related Pseudogenes:

Kansl2-ps5

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	131,548,062 - 131,564,876 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	131,548,062 - 131,564,753 (-)	Ensembl				GRCr8
mRatBN7.2	7	129,669,031 - 129,685,750 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	129,669,031 - 129,685,725 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	131,476,348 - 131,492,528 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	133,701,898 - 133,718,078 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	133,614,400 - 133,630,580 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	140,196,943 - 140,213,686 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	140,132,469 - 140,147,984 (-)	Ensembl			rn6	Rnor6.0
Rnor_6.0 Ensembl	7	140,196,953 - 140,213,050 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	114,700,497 - 114,717,449 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	137,266,031 - 137,282,137 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	126,159,998 - 126,176,078 (-)	NCBI		Celera
RGSC_v3.1	7	137,342,468 - 137,358,571 (-)	NCBI
Cytogenetic Map	7	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

intellectual disability (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(-)-epigallocatechin 3-gallate (ISO)

1,2-dichloroethane (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

amitrole (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

cisplatin (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

dicrotophos (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

ethanol (ISO)

fenthion (ISO)

flutamide (EXP)

formaldehyde (ISO)

FR900359 (ISO)

indometacin (ISO)

methidathion (ISO)

methyl methanesulfonate (ISO)

nefazodone (EXP)

nitrates (ISO)

ozone (ISO)

paracetamol (ISO)

pentachlorophenol (ISO)

potassium chromate (ISO)

selenium atom (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

tetrachloromethane (EXP)

triphenyl phosphate (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chromatin organization (IEA)

Cellular Component

cytosol (IEA,ISO)

histone acetyltransferase complex (IEA,ISO,ISS)

mitochondrion (IEA,ISO)

NSL complex (IBA,IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IEA)

plasma membrane (IEA,ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15489334	PMID:20018852

Genomics

Comparative Map Data

Kansl2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	131,548,062 - 131,564,876 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	131,548,062 - 131,564,753 (-)	Ensembl				GRCr8
mRatBN7.2	7	129,669,031 - 129,685,750 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	129,669,031 - 129,685,725 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	131,476,348 - 131,492,528 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	133,701,898 - 133,718,078 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	133,614,400 - 133,630,580 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	140,196,943 - 140,213,686 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	140,132,469 - 140,147,984 (-)	Ensembl			rn6	Rnor6.0
Rnor_6.0 Ensembl	7	140,196,953 - 140,213,050 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	114,700,497 - 114,717,449 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	137,266,031 - 137,282,137 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	126,159,998 - 126,176,078 (-)	NCBI		Celera
RGSC_v3.1	7	137,342,468 - 137,358,571 (-)	NCBI
Cytogenetic Map	7	q36	NCBI

KANSL2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	48,653,211 - 48,682,238 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	48,653,211 - 48,682,247 (-)	Ensembl			hg38	GRCh38
GRCh37	12	49,046,994 - 49,076,021 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	47,333,261 - 47,362,302 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	12	47,842,978 - 47,872,021 (-)	NCBI		Celera
Cytogenetic Map	12	q13.11	NCBI
HuRef	12	46,081,051 - 46,110,103 (-)	NCBI		HuRef
CHM1_1	12	49,012,779 - 49,041,852 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	48,615,234 - 48,644,264 (-)	NCBI		T2T-CHM13v2.0

Kansl2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	98,415,539 - 98,432,649 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	98,415,539 - 98,432,145 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	98,517,658 - 98,534,770 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	98,517,658 - 98,534,264 (-)	Ensembl			mm10	GRCm38
MGSCv37	15	98,349,532 - 98,364,652 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	98,346,846 - 98,362,272 (-)	NCBI		MGSCv36	mm8
Celera	15	100,666,646 - 100,681,756 (-)	NCBI		Celera
Cytogenetic Map	15	F1	NCBI
cM Map	15	54.52	NCBI

Kansl2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955500	7,553,357 - 7,571,158 (-)	Ensembl
ChiLan1.0	NW_004955500	7,552,747 - 7,572,991 (-)	NCBI	ChiLan1.0	ChiLan1.0

KANSL2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	45,497,865 - 45,526,678 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	45,494,625 - 45,523,472 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	40,063,603 - 40,092,393 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	40,941,614 - 40,970,079 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	40,941,614 - 40,970,079 (+)	Ensembl			panPan2	panpan1.1

KANSL2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	5,826,587 - 5,845,207 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	5,826,584 - 5,844,656 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	40,412,992 - 40,432,039 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	5,877,078 - 5,896,343 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	5,877,212 - 5,896,346 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	5,840,339 - 5,859,572 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	5,830,851 - 5,850,372 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	40,804,722 - 40,824,000 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Kansl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	66,605,362 - 66,627,204 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936512	6,538,241 - 6,557,455 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936512	6,537,499 - 6,558,124 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KANSL2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	79,281,588 - 79,314,995 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	79,281,584 - 79,315,011 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	82,748,272 - 82,779,984 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KANSL2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	44,898,203 - 44,926,479 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666037	201,221,689 - 201,249,820 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kansl2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	271,338,654 - 271,355,672 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Kansl2
60 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	161
Count of miRNA genes:	134
Interacting mature miRNAs:	145
Transcripts:	ENSRNOT00000014875, ENSRNOT00000073299
Prediction methods:	Miranda, Pita, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	82111382	132099989	Rat
1354582	Stl11	Serum triglyceride level QTL 11	3.42		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	121393075	137014596	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	98549867	137014596	Rat
1300112	Bp183	Blood pressure QTL 183	3.51		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	119280025	135560836	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	104186212	135371468	Rat
631687	Hcas1	Hepatocarcinoma susceptibility QTL 1	3.9	0.001	liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	7	93302009	131686183	Rat
1331748	Bp215	Blood pressure QTL 215	4.043		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	110725024	135371468	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	100548246	137014596	Rat
61397	Bw17	Body weight QTL 17	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	7	95485047	137014596	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	82111245	134948181	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	115313999	136544683	Rat
2299163	Iddm34	Insulin dependent diabetes mellitus QTL 34	2.71		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	7	116269196	132020414	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	92362341	137014596	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	71827901	136544683	Rat

Markers in Region

RH128148

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	7	q36	UniSTS

AA849021

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_5.0	14	86,593,683 - 86,593,795	UniSTS	Rnor5.0
Rnor_5.0	X	114,700,659 - 114,700,771	UniSTS	Rnor5.0
RGSC_v3.4	14	86,310,262 - 86,310,374	UniSTS	RGSC3.4
RGSC_v3.4	7	137,266,170 - 137,266,282	UniSTS	RGSC3.4
Celera	14	79,423,959 - 79,424,071	UniSTS
Celera	7	126,160,137 - 126,160,249	UniSTS
RH 3.4 Map	14	577.4	UniSTS
Cytogenetic Map	7	q36	UniSTS
Cytogenetic Map	14	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
22	12	73	195	125	120	77	98	77	12	414	216	11	162	91	111	43	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001004244	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001421308	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008765693	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008765694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263374	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263375	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC129405	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC079169	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC169120	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK474940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO404725	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EF076771	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000081766 ⟹ ENSRNOP00000072703

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	140,132,469 - 140,147,984 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000086886 ⟹ ENSRNOP00000073779

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	131,548,062 - 131,564,753 (-)	Ensembl
mRatBN7.2 Ensembl	7	129,669,031 - 129,685,725 (-)	Ensembl
Rnor_6.0 Ensembl	7	140,197,530 - 140,213,045 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000090730 ⟹ ENSRNOP00000072729

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	129,669,049 - 129,685,723 (-)	Ensembl
Rnor_6.0 Ensembl	7	140,196,953 - 140,213,050 (-)	Ensembl

RefSeq Acc Id:

NM_001004244 ⟹ NP_001004244

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	131,548,068 - 131,564,780 (-)	NCBI
mRatBN7.2	7	129,669,037 - 129,685,750 (-)	NCBI
Rnor_6.0	7	140,196,947 - 140,213,053 (-)	NCBI
Rnor_5.0	X	114,700,497 - 114,717,449 (-)	NCBI
RGSC_v3.4	7	137,266,031 - 137,282,137 (-)	RGD
Celera	7	126,159,998 - 126,176,078 (-)	RGD

Sequence:

show sequence

GTTTTGGTATGAACAGGATTCGGATTCACGTCTTGCCAACGAATCGGGGGAGGATCACCCCAGT
GCCCAGATCTCAGGAGCCCCTCTCTTGTTCGTTCACTCACCGCCCATGCTCTCAGCCGCGTCTG
GAGGGGCAGGAGTTTTGTCTTAAGCATATTCTTGAAGACAAGAATGCACCCTTCAAACAATGTA
GTTACATTTCGACGAAGAATGGGAAGAGGTGCCCCAGTGCTGCCCCAAAGCCTGAGAAGAAAGA
TGGGGTGTCTTTCTGTGCTGAACATGCTCGAAGGAATGCCCTAGCACTTCATGCTCAAATGAAG
AAGAGTAACCCAGGCCCTATGGGTGAAACCCTCTTGTGCCAGTTGAGCTCATATGCTAAAACAG
AGCTGGGCTCGCAGACCCCAGAGAGTAGCCGAAGCGAGGCGAGCCGGATACTGGATGAAGACAG
CTGGAGTGATGGGGACCAGGAACCCATTACTGTGGATCAGACATGGAGAGGTGACCCTGACAGT
GAAGCTGATAGCATAGACAGTGATCAAGAAGATCCCCTAAAACATGCGGGTGTCTATACAGCCG
AGGAGGTGGCTCTTATCATGAGAGAAAAGCTGATTCGTTTGCAGTCTTTGTACATTGATCAGTT
TAAACGACTACAGCACCTGCTCAAAGAGAAGAAGCGCCGTTACTTACATAATCGGAAAGTGGAA
CACGAAGCTTTAGGTAGTAGTCTCCTGACTGGCCCCGAGGGACTTTTGGCCAAAGAGAGAGAGA
ATTTAAAGCGACTAAAATGTCTCAGGCGATACCGTCAACGCTATGGAGTAGAAGCCTTACTACA
CAGGCAGCTGAAGGAACGCAGAATGCTGGCCACAGAGGGGGCTGCTCAACAGGCTCATACCACT
CGTTCCAGTCAGAGGTGCTTAGCCTTTGTGGATGATGTTCGCTGCTCCAATCAGTCTCTTCCGA
TGACCAGACACTGCCTTACCCATATCTGTCAGGATACAAATCAGGTTCTCTTCAAATGCTGCCA
GGGATCTGAAGAGGTACCCTGTAACAAACCAGTTCCTGTAAGCCTTTCTGAGGACCCCTGCTGT
CCACTGCACTTCCAGTTGCCTCCTCAGATGTATAAGCCCGAGCAGGTACTGTCTGTGCCAGACG
GTCTGGAAGCCGGCCCCATGGATCTGTACTTGAGTGCTGCCGAGCTTCAGCCCACTGAGAGCTT
ACCACTGGAGCTCAGTGACGACTTGGATGTCGTAGGTGATGGCATGCCGTGCCCTCCATCGCCC
TTGCTCTTTGATCCCTCCCTAACTCTAGAAGATCATTCCGTCACTGAAATTGCCGGAGGCCCAG
GACAGATACAGGTGGCTGGGGATGGGTGCAGATCCCAGGGACCTCATAATGTAGAGAAAACCTG
TGCACCATTCCCTCAGCGTGGATTGGCTACTGCAAATGGAAAACCAGAGCCCACTTCTATCAGT
TGACAGTTCATTCTGGGATTGCTCACCGCCTTTGGATTTGAACTCTCCATTCTTCAGACAAGTG
TATCTTTGATCATCTCTCACTGAACAGGGACAGCTCAGACCACGTTGTTTCCTTCGGGGCTTGA
GAGTGCTGTAGACAAACATAACCCAAGTCTCTGTGATGACAAGTTAGTATTTAAGTTTTGGGAT
TTTTTGCGAGGAAGAGCGTGAGGTGCTCCCTGCCTTTGAGATGCAGTGCCTATTGGAGACATTT
ATACTGGGACTTCTGAGCCATGGGCTGAGATCCACGTGGATGTCTAGGCGGGGTTGGCTGTGGT
GAAGAACGGTGCTCTTCAGGTGTTGGCTCTTAGTCTCTGTAGCCGTATCTAAAGCTGTATTTAA
GCCTTTCCTCTGCTCCACATCATTGGGCAATATAAACCCCCTTTCCTAGTGAACCGACTGAGAA
AAGCAGTTCACAGGTCTGGGTTCTCCTTAATTATTCTTGCTTTTAATTTATGTAAATTTCTGTG
GTGGCTCCTTCATGTAAGATATAGTGAAGTTATTGTATATAGTTTCTATTAAATGTTAAAATGT
TATGAAAATAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001421308 ⟹ NP_001408237

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	131,548,062 - 131,564,753 (-)	NCBI
mRatBN7.2	7	129,669,031 - 129,685,723 (-)	NCBI

RefSeq Acc Id:

XM_008765693 ⟹ XP_008763915

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	131,548,062 - 131,564,782 (-)	NCBI
mRatBN7.2	7	129,669,031 - 129,685,743 (-)	NCBI
Rnor_6.0	7	140,196,947 - 140,213,608 (-)	NCBI

Sequence:

show sequence

GCGGCGGGGAGGTAAGATGGCGCCGTGCCGGGCTCTTCTCCTTTGCCGTTAGGCTGCTGCTCGC
CCTTTCTATCAACTCAGCGCGGTTTTGGTATGAACAGGATTCGGATTCACGTCTTGCCAACGAA
TCGGGGGAGGATCACCCCAGTGCCCAGATCTCAGGAGCCCCTCTCTTGTTCGTTCACTCACCGC
CCATGCTCTCAGCCGCGTCTGGAGGGGCAGGAGTTTTGTCTTAAGCATATTCTTGAAGACAAGA
ATGCACCCTTCAAACAATGTAGTTACATTTCGACGAAGAATGGGAAGAGGTGCCCCAGTGCTGC
CCCAAAGCCTGAGAAGAAAGATGGGGTGTCTTTCTGTGCTGAACATGCTCGAAGGAATGCCCTA
GCACTTCATGCTCAAATGAAGAAGAGTAACCCAGGCCCTATGGGTGAAACCCTCTTGTGCCAGT
TGAGCTCATATGCTAAAACAGAGCTGGGCTCGCAGACCCCAGAGAGTAGCCGAAGCGAGGCGAG
CCGGATACTGGATGAAGACAGCTGGAGTGATGGGGACCAGGAACCCATTACTGTGGATCAGACA
TGGAGAGGTGACCCTGACAGTGAAGCTGATAGCATAGACAGTGATCAAGAAGATCCCCTAAAAC
ATGCGGGTGTCTATACAGCCGAGGAGGTGGCTCTTATCATGAGAGAAAAGCTGATTCGTTTGCA
GTCTTTGTACATTGATCAGTTTAAACGACTACAGCACCTGCTCAAAGAGAAGAAGCGCCGTTAC
TTACATAATCGGAAAGTGGAACACGAAGCTTTAGGTAGTAGTCTCCTGACTGGCCCCGAGGGAC
TTTTGGCCAAAGAGAGAGAGAATTTAAAGCGACTAAAATGTCTCAGGCGATACCGTCAACGCTA
TGGAGTAGAAGCCTTACTACACAGGCAGCTGAAGGAACGCAGAATGCTGGCCACAGAGGGGGCT
GCTCAACAGGCTCATACCACTCGTTCCAGTCAGAGGTGCTTAGCCTTTGTGGATGATGTTCGCT
GCTCCAATCAGTCTCTTCCGATGACCAGACACTGCCTTACCCATATCTGTCAGGATACAAATCA
GGTTCTCTTCAAATGCTGCCAGGGATCTGAAGAGGTACCCTGTAACAAACCAGTTCCTGTAAGC
CTTTCTGAGGACCCCTGCTGTCCACTGCACTTCCAGTTGCCTCCTCAGATGTATAAGCCCGAGC
AGGTACTGTCTGTGCCAGACGGTCTGGAAGCCGGCCCCATGGATCTGTACTTGAGTGCTGCCGA
GCTTCAGCCCACTGAGAGCTTACCACTGGAGCTCAGTGACGACTTGGATGTCGTAGGTGATGGC
ATGCCGTGCCCTCCATCGCCCTTGCTCTTTGATCCCTCCCTAACTCTAGAAGATCATTCCGTCA
CTGAAATTGCCGGAGGCCCAGGACAGATACAGGTGGCTGGGGATGGGTGCAGATCCCAGGGACC
TCATAATGTAGAGAAAACCTGTGCACCATTCCCTCAGCGTGGATTGGCTACTGCAAATGGAAAA
CCAGAGCCCACTTCTATCAGTTGACAGTTCATTCTGGGATTGCTCACCGCCTTTGGATTTGAAC
TCTCCATTCTTCAGACAAGTGTATCTTTGATCATCTCTCACTGAACAGGGACAGCTCAGACCAC
GTTGTTTCCTTCGGGGCTTGAGAGTGCTGTAGACAAACATAACCCAAGTCTCTGTGATGACAAG
TTAGTATTTAAGTTTTGGGATTTTTTGCGAGGAAGAGCGTGAGGTGCTCCCTGCCTTTGAGATG
CAGTGCCTATTGGAGACATTTATACTGGGACTTCTGAGCCATGGGCTGAGATCCACGTGGATGT
CTAGGCGGGGTTGGCTGTGGTGAAGAACGGTGCTCTTCAGGTGTTGGCTCTTAGTCTCTGTAGC
CGTATCTAAAGCTGTATTTAAGCCTTTCCTCTGCTCCACATCATTGGGCAATATAAACCCCCTT
TCCTAGTGAACCGACTGAGAAAAGCAGTTCACAGGTCTGGGTTCTCCTTAATTATTCTTGCTTT
TAATTTATGTAAATTTCTGTGGTGGCTCCTTCATGTAAGATATAGTGAAGTTATTGTATATAGT
TTCTATTAAATGTTAAAATGTTATGAAAATA

hide sequence

RefSeq Acc Id:

XM_063263374 ⟹ XP_063119444

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	131,548,062 - 131,561,940 (-)	NCBI

RefSeq Acc Id:

XM_063263375 ⟹ XP_063119445

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	131,555,596 - 131,564,876 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001004244	(Get FASTA)	NCBI Sequence Viewer
	NP_001408237	(Get FASTA)	NCBI Sequence Viewer
	XP_008763915	(Get FASTA)	NCBI Sequence Viewer
	XP_063119444	(Get FASTA)	NCBI Sequence Viewer
	XP_063119445	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79169	(Get FASTA)	NCBI Sequence Viewer
	EDL87055	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000072729.2
	ENSRNOP00000073779
	ENSRNOP00000073779.2
GenBank Protein	Q6AY70	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001004244 ⟸ NM_001004244

- UniProtKB:

G3V7H0 (UniProtKB/Swiss-Prot), Q6AY70 (UniProtKB/Swiss-Prot), A0A0G2K3M8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNRIRIHVLPTNRGRITPVPRSQEPLSCSFTHRPCSQPRLEGQEFCLKHILEDKNAPFKQCSYI
STKNGKRCPSAAPKPEKKDGVSFCAEHARRNALALHAQMKKSNPGPMGETLLCQLSSYAKTELG
SQTPESSRSEASRILDEDSWSDGDQEPITVDQTWRGDPDSEADSIDSDQEDPLKHAGVYTAEEV
ALIMREKLIRLQSLYIDQFKRLQHLLKEKKRRYLHNRKVEHEALGSSLLTGPEGLLAKERENLK
RLKCLRRYRQRYGVEALLHRQLKERRMLATEGAAQQAHTTRSSQRCLAFVDDVRCSNQSLPMTR
HCLTHICQDTNQVLFKCCQGSEEVPCNKPVPVSLSEDPCCPLHFQLPPQMYKPEQVLSVPDGLE
AGPMDLYLSAAELQPTESLPLELSDDLDVVGDGMPCPPSPLLFDPSLTLEDHSVTEIAGGPGQI
QVAGDGCRSQGPHNVEKTCAPFPQRGLATANGKPEPTSIS

hide sequence

RefSeq Acc Id:	XP_008763915 ⟸ XM_008765693
- Peptide Label:	isoform X1
- UniProtKB:	G3V7H0 (UniProtKB/Swiss-Prot), Q6AY70 (UniProtKB/Swiss-Prot), A0A0G2K3M8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNRIRIHVLPTNRGRITPVPRSQEPLSCSFTHRPCSQPRLEGQEFCLKHILEDKNAPFKQCSYI STKNGKRCPSAAPKPEKKDGVSFCAEHARRNALALHAQMKKSNPGPMGETLLCQLSSYAKTELG SQTPESSRSEASRILDEDSWSDGDQEPITVDQTWRGDPDSEADSIDSDQEDPLKHAGVYTAEEV ALIMREKLIRLQSLYIDQFKRLQHLLKEKKRRYLHNRKVEHEALGSSLLTGPEGLLAKERENLK RLKCLRRYRQRYGVEALLHRQLKERRMLATEGAAQQAHTTRSSQRCLAFVDDVRCSNQSLPMTR HCLTHICQDTNQVLFKCCQGSEEVPCNKPVPVSLSEDPCCPLHFQLPPQMYKPEQVLSVPDGLE AGPMDLYLSAAELQPTESLPLELSDDLDVVGDGMPCPPSPLLFDPSLTLEDHSVTEIAGGPGQI QVAGDGCRSQGPHNVEKTCAPFPQRGLATANGKPEPTSIS hide sequence

Ensembl Acc Id:

ENSRNOP00000072729 ⟸ ENSRNOT00000090730

Ensembl Acc Id:

ENSRNOP00000073779 ⟸ ENSRNOT00000086886

Ensembl Acc Id:

ENSRNOP00000072703 ⟸ ENSRNOT00000081766

RefSeq Acc Id:	NP_001408237 ⟸ NM_001421308
- UniProtKB:	Q6AY70 (UniProtKB/Swiss-Prot), G3V7H0 (UniProtKB/Swiss-Prot), A0A0G2K3M8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063119444 ⟸ XM_063263374
- Peptide Label:	isoform X2
- UniProtKB:	A0A0G2K3Q1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063119445 ⟸ XM_063263375
- Peptide Label:	isoform X3

Protein Domains

KANL2-like probable zinc-finger

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AY70-F1-model_v2	AlphaFold	Q6AY70	1-488	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1303127	AgrOrtholog
BioCyc Gene	G2FUF-32133	BioCyc
Ensembl Genes	ENSRNOG00000053541	Ensembl
	ENSRNOG00000060185	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000086886	ENTREZGENE
	ENSRNOT00000086886.2	UniProtKB/Swiss-Prot
	ENSRNOT00000090730.2	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7129861	IMAGE-MGC_LOAD
InterPro	NSL2	UniProtKB/Swiss-Prot
	Potential_DNA-bd	UniProtKB/Swiss-Prot
KEGG Report	rno:300206	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94200	IMAGE-MGC_LOAD
NCBI Gene	300206	ENTREZGENE
PANTHER	KAT8 REGULATORY NSL COMPLEX SUBUNIT 2	UniProtKB/Swiss-Prot
	PTHR13453	UniProtKB/Swiss-Prot
Pfam	zf-C3Hc3H	UniProtKB/Swiss-Prot
PhenoGen	Kansl2	PhenoGen
RatGTEx	ENSRNOG00000053541	RatGTEx
	ENSRNOG00000060185	RatGTEx
UniProt	A0A0G2K3M8	ENTREZGENE, UniProtKB/TrEMBL
	A0A0G2K3Q1	ENTREZGENE
	G3V7H0	ENTREZGENE
	KANL2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	G3V7H0	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Kansl2	KAT8 regulatory NSL complex subunit 2	LOC103690317	KAT8 regulatory NSL complex subunit 2	Data merged from RGD:9332946	737654	PROVISIONAL
2014-08-25	LOC103690317	KAT8 regulatory NSL complex subunit 2			Symbol and Name status set to provisional	70820	PROVISIONAL
2011-12-06	Kansl2	KAT8 regulatory NSL complex subunit 2	RGD1303127	similar to hypothetical protein FLJ20436	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	RGD1303127	similar to hypothetical protein FLJ20436	MGC94200		Symbol updated	1299863	APPROVED
2005-09-30	MGC94200				Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar