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Gene: Fut8 (fucosyltransferase 8) Rattus norvegicus

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Symbol:

Fut8

Name:

fucosyltransferase 8

RGD ID:

1303096

Description:

Predicted to enable glycoprotein 6-alpha-L-fucosyltransferase activity. Predicted to be involved in GDP-L-fucose metabolic process; N-glycan fucosylation; and protein N-linked glycosylation via asparagine. Predicted to act upstream of or within several processes, including N-glycan processing; cell surface receptor signaling pathway; and fibroblast migration. Predicted to be located in Golgi cisterna membrane. Orthologous to human FUT8 (fucosyltransferase 8); PARTICIPATES IN keratan sulfate biosynthetic pathway; N-linked glycan biosynthetic pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

alpha-(1,6)-fucosyltransferase; alpha1-6FucT; fucosyltransferase 8 (alpha (1,6) fucosyltransferase); GDP-fucose--glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; glycoprotein 6-alpha-L-fucosyltransferase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FUT8 (fucosyltransferase 8)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Fut8 (fucosyltransferase 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Fut8 (fucosyltransferase 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FUT8 (fucosyltransferase 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FUT8 (fucosyltransferase 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Fut8 (fucosyltransferase 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FUT8 (fucosyltransferase 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FUT8 (fucosyltransferase 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Fut8 (fucosyltransferase 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Fut8 (fucosyltransferase 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	FUT8 (fucosyltransferase 8)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Fut8 (fucosyltransferase 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fut8a (fucosyltransferase 8a (alpha (1,6) fucosyltransferase))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fut8b (fucosyltransferase 8b (alpha (1,6) fucosyltransferase))	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fut8b (fucosyltransferase 8b (alpha (1,6) fucosyltransferase))	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	fut-8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	FucT6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	fut8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	101,682,354 - 101,909,784 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	101,683,007 - 101,909,775 (+)	Ensembl				GRCr8
mRatBN7.2	6	95,949,246 - 96,176,677 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	95,949,991 - 96,176,677 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	96,431,422 - 96,589,699 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	96,729,964 - 96,888,239 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	96,162,558 - 96,299,949 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	100,305,957 - 100,537,208 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	100,337,226 - 100,537,224 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	109,782,471 - 109,861,661 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	6	109,896,811 - 109,922,225 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	99,871,195 - 100,010,833 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	94,453,397 - 94,591,184 (+)	NCBI		Celera
RGSC_v3.1	6	99,874,650 - 100,014,289 (+)	NCBI
Cytogenetic Map	6	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Congenital Disorder of Glycosylation with Defective Fucosylation 1 (ISO)

genetic disease (ISO)

pulmonary emphysema (ISS)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-diaminotoluene (ISO)

2,4-dinitrotoluene (EXP)

3-chloropropane-1,2-diol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3-methylcholanthrene (ISO)

4,4'-sulfonyldiphenol (ISO)

acetamide (EXP)

afimoxifene (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

Aroclor 1254 (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-chloroethyl) sulfide (EXP)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

caffeine (ISO)

calcitriol (ISO)

carmustine (ISO)

chlordecone (ISO)

choline (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

cocaine (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dibenzo[a,l]pyrene (ISO)

diethyl pyrocarbonate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

etoposide (ISO)

folic acid (ISO)

fucose (ISO)

fulvestrant (ISO)

GDP (ISO)

gentamycin (EXP)

glafenine (EXP)

glyphosate (EXP)

GTP (ISO)

guanosine 5'-monophosphate (ISO)

indometacin (ISO)

iodomethane (ISO)

isotretinoin (ISO)

L-methionine (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

menadione (ISO)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

N-nitrosodiethylamine (ISO)

nickel dichloride (ISO)

oxaliplatin (EXP)

p-chloromercuribenzoic acid (ISO)

paracetamol (EXP)

PCB138 (EXP)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

Phenylglyoxal (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

piroxicam (ISO)

potassium chromate (ISO)

pyridoxal 5'-phosphate (ISO)

quercetin (ISO)

rotenone (EXP)

SB 431542 (ISO)

sodium arsenite (ISO)

tamoxifen (ISO)

temozolomide (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

trovafloxacin (ISO)

uranium atom (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell migration (ISO)

GDP-L-fucose metabolic process (IEA,ISO,ISS)

glycoprotein biosynthetic process (IEA)

integrin-mediated signaling pathway (ISO)

N-glycan processing (IEA,ISO)

protein N-linked glycosylation (IBA,IEA,ISO,ISS)

protein O-linked glycosylation via fucose (IEA)

receptor metabolic process (ISO)

regulation of cellular response to oxidative stress (ISO)

regulation of gene expression (ISO)

respiratory gaseous exchange by respiratory system (ISO)

transforming growth factor beta receptor signaling pathway (ISO)

Cellular Component

Golgi cisterna membrane (IEA)

membrane (IEA)

Molecular Function

alpha-(1->6)-fucosyltransferase activity (IBA,IEA,ISO)

glycoprotein 6-alpha-L-fucosyltransferase activity (IEA,ISO,ISS)

glycosyltransferase activity (IEA,ISO)

hexosyltransferase activity (IEA)

protein binding (ISO)

SH3 domain binding (IEA)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

keratan sulfate biosynthetic pathway (IEA)

N-linked glycan biosynthetic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Information Derived from GenBank Report	RGD, Sept. 2003

Additional References at PubMed

PMID:10902914	PMID:16236725	PMID:17043354	PMID:17172260	PMID:19199708	PMID:19946888	PMID:21208406	PMID:24619415

Genomics

Comparative Map Data

Fut8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	101,682,354 - 101,909,784 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	101,683,007 - 101,909,775 (+)	Ensembl				GRCr8
mRatBN7.2	6	95,949,246 - 96,176,677 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	95,949,991 - 96,176,677 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	96,431,422 - 96,589,699 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	96,729,964 - 96,888,239 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	96,162,558 - 96,299,949 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	100,305,957 - 100,537,208 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	100,337,226 - 100,537,224 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	109,782,471 - 109,861,661 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	6	109,896,811 - 109,922,225 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	99,871,195 - 100,010,833 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	94,453,397 - 94,591,184 (+)	NCBI		Celera
RGSC_v3.1	6	99,874,650 - 100,014,289 (+)	NCBI
Cytogenetic Map	6	q24	NCBI

FUT8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	65,356,842 - 65,744,121 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	65,410,592 - 65,744,125 (+)	Ensembl			hg38	GRCh38
GRCh37	14	65,877,310 - 66,210,839 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	64,947,593 - 65,279,715 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	14	65,205,885 - 65,279,714	NCBI
Celera	14	45,932,950 - 46,265,003 (+)	NCBI		Celera
Cytogenetic Map	14	q23.3	NCBI
HuRef	14	46,045,683 - 46,380,271 (+)	NCBI		HuRef
CHM1_1	14	65,815,455 - 66,148,980 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	59,615,360 - 59,948,716 (+)	NCBI		T2T-CHM13v2.0

Fut8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	77,284,878 - 77,522,770 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	77,284,899 - 77,523,112 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	12	77,237,430 - 77,475,998 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	77,238,125 - 77,476,338 (+)	Ensembl			mm10	GRCm38
MGSCv37	12	78,340,008 - 78,576,974 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	12	78,157,861 - 78,394,827 (+)	NCBI		MGSCv36	mm8
Celera	12	78,319,280 - 78,556,375 (+)	NCBI		Celera
Cytogenetic Map	12	C3	NCBI
cM Map	12	35.46	NCBI

Fut8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955466	4,246,336 - 4,399,751 (-)	Ensembl
ChiLan1.0	NW_004955466	4,248,414 - 4,481,942 (-)	NCBI	ChiLan1.0	ChiLan1.0

FUT8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	66,445,179 - 66,840,607 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	65,730,043 - 66,058,095 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	45,983,149 - 46,310,318 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	64,867,169 - 65,193,117 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	65,016,869 - 65,193,111 (+)	Ensembl			panPan2	panpan1.1

FUT8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	39,670,629 - 39,972,729 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	39,825,246 - 39,972,612 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	39,517,785 - 39,663,663 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	39,894,253 - 40,195,165 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	39,895,335 - 40,194,870 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	39,668,378 - 39,816,282 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	39,740,833 - 39,888,597 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	40,099,999 - 40,247,661 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Fut8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	64,850,261 - 65,179,285 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936495	9,115,938 - 9,344,068 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936495	9,012,425 - 9,341,538 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FUT8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	89,519,730 - 89,680,489 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	89,395,637 - 89,680,502 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	95,815,278 - 96,101,019 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FUT8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	42,627,340 - 42,965,505 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	42,788,132 - 42,968,124 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666053	30,814,869 - 31,156,411 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fut8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	35,264,019 - 35,458,277 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624734	35,257,666 - 35,617,275 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Fut8
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	7	91,462,574 - 91,593,932 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Fut8
1259 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	36
Count of miRNA genes:	31
Interacting mature miRNAs:	35
Transcripts:	ENSRNOT00000011220
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2293088	Iddm28	Insulin dependent diabetes mellitus QTL 28	5.21		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	6	68767270	135411972	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	88019181	136741135	Rat
61329	Eae9	Experimental allergic encephalomyelitis QTL 9	3.7		body mass (VT:0001259)	change in body weight (CMO:0002045)	6	84490437	129490437	Rat
2313399	Anxrr28	Anxiety related response QTL 28			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	6	101593607	138161926	Rat
1331789	Rf37	Renal function QTL 37	3.224		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	6	86494122	112380234	Rat
1331725	Bp212	Blood pressure QTL 212	3.52475		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	99437079	125323237	Rat
1331722	Thshl1	Thyroid stimulating hormone level QTL 1	11.7	0.0001	blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	6	99708426	112483760	Rat
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	71278722	116278722	Rat
70176	Mcsm1	Mammary carcinoma susceptibility modifier QTL 1			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	64367996	109367996	Rat
10054138	Gmadr3	Adrenal mass QTL 3	3.68	0.00045	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	6	90871046	135871046	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	93560258	136550638	Rat
1641917	Colcr5	Colorectal carcinoma resistance QTL 5	3.18	0.0009	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	6	98944780	143944780	Rat
61414	Pia3	Pristane induced arthritis QTL 3	4.5		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	6	100704576	136029228	Rat
724524	Uae2	Urinary albumin excretion QTL 2	2.7	0.0005	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	79198463	144254945	Rat
737827	Hcar11	Hepatocarcinoma resistance QTL 11	4.4		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	6	46050607	116278722	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	93778632	138778632	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	20859430	113082285	Rat
2293837	Kiddil1	Kidney dilation QTL 1	3.7		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	86867923	110125012	Rat
2293842	Kiddil3	Kidney dilation QTL 3	4.3		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	86867923	110125012	Rat
10054123	Srcrt6	Stress Responsive Cort QTL 6	2.5	0.0043	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	90871046	135871046	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	93560258	136550638	Rat
1576302	Schws4	Schwannoma susceptibility QTL 4		0.0078	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	78204640	123204640	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	93560258	136550638	Rat
1300075	Glom7	Glomerulus QTL 7	5.6	0.0000002	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	6	76937178	121937178	Rat
12801471	Schws9	Schwannoma susceptibility QTL 9			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	101593607	146593607	Rat

Markers in Region

RH127620

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	96,176,270 - 96,176,484 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	100,536,802 - 100,537,015	NCBI	Rnor6.0
Rnor_5.0	6	109,922,490 - 109,922,703	UniSTS	Rnor5.0
RGSC_v3.4	6	100,011,098 - 100,011,311	UniSTS	RGSC3.4
Celera	6	94,591,449 - 94,591,662	UniSTS
RH 3.4 Map	6	680.9	UniSTS
Cytogenetic Map	6	q24	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001002289	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001412189	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594263	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112660	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262247	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AJ781406	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FN668936	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FN668937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FN668938	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FN668939	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FN668940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227928	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ231659	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GM744703	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000011220 ⟹ ENSRNOP00000011220

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	101,683,007 - 101,909,775 (+)	Ensembl
mRatBN7.2 Ensembl	6	95,949,991 - 96,176,671 (+)	Ensembl
Rnor_6.0 Ensembl	6	100,337,226 - 100,537,224 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096219 ⟹ ENSRNOP00000089026

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	101,771,572 - 101,909,775 (+)	Ensembl
mRatBN7.2 Ensembl	6	96,043,141 - 96,176,677 (+)	Ensembl

RefSeq Acc Id:

NM_001002289 ⟹ NP_001002289

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	101,682,354 - 101,909,784 (+)	NCBI
mRatBN7.2	6	95,949,246 - 96,176,677 (+)	NCBI
Rnor_6.0	6	100,397,053 - 100,536,537 (+)	NCBI
Rnor_5.0	6	109,782,471 - 109,861,661 (+)	NCBI
Rnor_5.0	6	109,896,811 - 109,922,225 (+)	NCBI
RGSC_v3.4	6	99,871,195 - 100,010,833 (+)	RGD
Celera	6	94,453,397 - 94,591,184 (+)	RGD

Sequence:

show sequence

ATGCGGGCATGGACTGGTTCCTGGCGTTGGATTATGCTCATTCTTTTTGCCTGGGGGACCTTGT
TGTTTTATATAGGTGGTCATTTGGTTCGAGATAATGACCACCCTGATCACTCTAGCAGAGAACT
CTCCAAGATTCTTGCAAAGCTTGAACGCTTAAAACAACAAAATGAAGACTTGAGGCGAATGGCT
GAGTCTCTACGAATACCAGAAGGCCCCATTGACCAGGGGACGGCTACGGGAAGAGTCCGTGTTT
TAGAAGAACAGCTTGTTAAGGCCAAAGAACAGATTGAAAATTACAAGAAACAAGCCAGAAATGG
TCTGGGGAAGGATCATGAACTCTTAAGGAGGAGGATTGAAAATGGAGCTAAAGAGCTCTGGTTT
TTTCTACAAAGTGAACTGAAGAAATTAAAGCATCTAGAAGGAAATGAACTCCAAAGACATGCAG
ATGAAATTCTTTTGGATTTAGGACACCATGAAAGGTCTATCATGACGGATCTATACTACCTCAG
TCAAACAGATGGAGCAGGGGATTGGCGTGAAAAAGAGGCCAAAGATCTGACAGAGCTGGTCCAG
CGGAGAATAACTTATCTCCAGAATCCCAAGGACTGCAGCAAAGCCAGGAAGCTGGTGTGTAACA
TCAATAAGGGCTGTGGCTATGGTTGCCAACTCCATCACGTGGTCTACTGTTTCATGATTGCTTA
TGGCACCCAGCGAACACTCATCTTGGAATCTCAGAATTGGCGCTATGCTACTGGTGGATGGGAG
ACTGTGTTTAGACCTGTAAGTGAGACATGCACAGACAGATCTGGCCTCTCCACTGGACACTGGT
CAGGTGAAGTGAATGACAAAAATATTCAAGTGGTGGAGCTCCCCATTGTAGACAGCCTCCATCC
TCGGCCTCCTTACTTACCACTGGCTGTTCCAGAAGACCTTGCAGATCGACTCGTAAGAGTCCAT
GGTGATCCTGCAGTGTGGTGGGTGTCCCAGTTCGTCAAATATTTGATTCGTCCACAACCTTGGC
TAGAAAAGGAAATAGAAGAAGCCACCAAGAAGCTTGGCTTCAAACATCCAGTCATTGGAGTCCA
TGTCAGACGCACAGACAAAGTGGGAACAGAGGCAGCCTTCCATCCCATCGAAGAGTACATGGTA
CATGTTGAAGAACATTTTCAGCTTCTCGCACGCAGAATGCAAGTGGATAAAAAAAGAGTATATC
TGGCTACCGATGACCCTGCTTTGTTAAAGGAGGCAAAGACAAAGTACTCCAATTATGAATTTAT
TAGTGATAACTCTATTTCTTGGTCAGCTGGATTACACAATCGGTACACAGAAAATTCACTTCGG
GGCGTGATCCTGGATATACACTTTCTCTCTCAGGCTGACTTCCTAGTGTGTACTTTTTCATCCC
AGGTCTGTCGGGTTGCTTATGAAATCATGCAAACCCTGCATCCTGATGCCTCTGCAAACTTCCA
CTCTTTAGATGACATCTACTATTTTGGAGGCCAAAATGCCCACAACCAGATTGCCGTTTATCCT
CACAAACCTCGAACTGATGAGGAAATTCCAATGGAACCTGGAGATATCATTGGTGTGGCTGGAA
ACCATTGGGATGGTTATTCTAAAGGTGTCAACAGAAAACTTGGAAAAACAGGCTTATATCCCTC
CTACAAAGTCCGAGAGAAGATAGAAACAGTCAAGTATCCCACATATCCTGAAGCTGAAAAATAG

hide sequence

RefSeq Acc Id:

NM_001412189 ⟹ NP_001399118

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	101,683,288 - 101,909,784 (+)	NCBI
mRatBN7.2	6	95,950,180 - 96,176,677 (+)	NCBI

RefSeq Acc Id:

XM_039112660 ⟹ XP_038968588

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	101,683,339 - 101,909,784 (+)	NCBI
mRatBN7.2	6	95,950,236 - 96,176,677 (+)	NCBI

RefSeq Acc Id:

XM_063262247 ⟹ XP_063118317

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	101,683,771 - 101,909,784 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001002289	(Get FASTA)	NCBI Sequence Viewer
	NP_001399118	(Get FASTA)	NCBI Sequence Viewer
	XP_038968588	(Get FASTA)	NCBI Sequence Viewer
	XP_063118317	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAH03674	(Get FASTA)	NCBI Sequence Viewer
	CAV31714	(Get FASTA)	NCBI Sequence Viewer
	CBJ94503	(Get FASTA)	NCBI Sequence Viewer
	CBJ94504	(Get FASTA)	NCBI Sequence Viewer
	CBJ94505	(Get FASTA)	NCBI Sequence Viewer
	EDM03684	(Get FASTA)	NCBI Sequence Viewer
	EDM03685	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000011220
	ENSRNOP00000089026
GenBank Protein	Q6EV76	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001002289 ⟸ NM_001002289

- UniProtKB:

Q6EV76 (UniProtKB/Swiss-Prot), D4IGX4 (UniProtKB/TrEMBL), A6HCC9 (UniProtKB/TrEMBL), D4IGX5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRAWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDLRRMA
ESLRIPEGPIDQGTATGRVRVLEEQLVKAKEQIENYKKQARNGLGKDHELLRRRIENGAKELWF
FLQSELKKLKHLEGNELQRHADEILLDLGHHERSIMTDLYYLSQTDGAGDWREKEAKDLTELVQ
RRITYLQNPKDCSKARKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWE
TVFRPVSETCTDRSGLSTGHWSGEVNDKNIQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVH
GDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMV
HVEEHFQLLARRMQVDKKRVYLATDDPALLKEAKTKYSNYEFISDNSISWSAGLHNRYTENSLR
GVILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQIAVYP
HKPRTDEEIPMEPGDIIGVAGNHWDGYSKGVNRKLGKTGLYPSYKVREKIETVKYPTYPEAEK

hide sequence

Ensembl Acc Id:

ENSRNOP00000011220 ⟸ ENSRNOT00000011220

RefSeq Acc Id:	XP_038968588 ⟸ XM_039112660
- Peptide Label:	isoform X2
- UniProtKB:	Q6EV76 (UniProtKB/Swiss-Prot)

Ensembl Acc Id:

ENSRNOP00000089026 ⟸ ENSRNOT00000096219

RefSeq Acc Id:	NP_001399118 ⟸ NM_001412189
- UniProtKB:	Q6EV76 (UniProtKB/Swiss-Prot), D4IGX4 (UniProtKB/TrEMBL), A6HCC9 (UniProtKB/TrEMBL), D4IGX5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063118317 ⟸ XM_063262247
- Peptide Label:	isoform X1
- UniProtKB:	Q6EV76 (UniProtKB/Swiss-Prot), A6HCC9 (UniProtKB/TrEMBL), D4IGX4 (UniProtKB/TrEMBL), D4IGX5 (UniProtKB/TrEMBL)

Protein Domains

GT23 SH3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6EV76-F1-model_v2	AlphaFold	Q6EV76	1-575	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1303096	AgrOrtholog
BioCyc Gene	G2FUF-37034	BioCyc
BioCyc Pathway	PWY-7426 [complex N-linked glycan biosynthesis (vertebrates)]	BioCyc
BioCyc Pathway Image	PWY-7426	BioCyc
Ensembl Genes	ENSRNOG00000008451	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000011220	ENTREZGENE
	ENSRNOT00000096219	ENTREZGENE
Gene3D-CATH	3.40.50.11350	UniProtKB/Swiss-Prot
	ESAT-6-like	UniProtKB/Swiss-Prot
	SH3 Domains	UniProtKB/Swiss-Prot
InterPro	Fut8	UniProtKB/Swiss-Prot
	Fut8_N_cat	UniProtKB/Swiss-Prot
	Fut8_SH3	UniProtKB/Swiss-Prot
	GT23_dom	UniProtKB/Swiss-Prot
	SH3-like_dom_sf	UniProtKB/Swiss-Prot
	SH3_domain	UniProtKB/Swiss-Prot
KEGG Report	rno:432392	UniProtKB/Swiss-Prot
NCBI Gene	432392	ENTREZGENE
PANTHER	ALPHA- 1,6 -FUCOSYLTRANSFERASE	UniProtKB/Swiss-Prot
	ALPHA-(1,6)-FUCOSYLTRANSFERASE	UniProtKB/Swiss-Prot
Pfam	FUT8_N_cat	UniProtKB/Swiss-Prot
	SH3_9	UniProtKB/Swiss-Prot
PhenoGen	Fut8	PhenoGen
PIRSF	Alpha1_6FUT_euk	UniProtKB/Swiss-Prot
PROSITE	GT23	UniProtKB/Swiss-Prot
	SH3	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000008451	RatGTEx
SMART	SH3	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50044	UniProtKB/Swiss-Prot
UniProt	A0A8I6AAW5_RAT	UniProtKB/TrEMBL
	A6HCC9	ENTREZGENE
	D4IGX4	ENTREZGENE, UniProtKB/TrEMBL
	D4IGX5	ENTREZGENE, UniProtKB/TrEMBL
	FUT8_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-04-13	Fut8	fucosyltransferase 8	Fut8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-18	Fut8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)	Fut8	fucosyltransferase 8	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-04	Fut8	fucosyltransferase 8	Fut8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-02-14	Fut8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

BioCyc Pathways

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

BioCyc Pathways