Crat (carnitine O-acetyltransferase) - Rat Genome Database

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Gene: Crat (carnitine O-acetyltransferase) Rattus norvegicus
Analyze
Symbol: Crat
Name: carnitine O-acetyltransferase
RGD ID: 1303031
Description: Enables carnitine O-acetyltransferase activity. Involved in fatty acid metabolic process. Predicted to be located in mitochondrion. Predicted to be active in peroxisome. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation. Orthologous to human CRAT (carnitine O-acetyltransferase); PARTICIPATES IN adrenoleukodystrophy pathway; carnitine-acylcarnitine translocase deficiency; fatty acid beta degradation pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: carnitine acetylase; carnitine acetyltransferase; CAT; MGC94385
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8334,073,504 - 34,087,099 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl334,073,506 - 34,087,099 (-)EnsemblGRCr8
mRatBN7.2313,675,684 - 13,689,282 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl313,675,684 - 13,689,255 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx316,747,217 - 16,760,812 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0325,332,179 - 25,345,774 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0323,578,162 - 23,591,743 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.038,967,984 - 8,981,959 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl38,968,417 - 8,981,362 (-)Ensemblrn6Rnor6.0
Rnor_5.0314,320,758 - 14,334,741 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.439,447,585 - 9,461,180 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera38,442,229 - 8,455,824 (-)NCBICelera
RGSC_v3.139,447,886 - 9,461,480 (-)NCBI
Cytogenetic Map3p12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(+)-schisandrin B  (EXP)
1,2-dichloroethane  (ISO)
1,4-benzoquinone  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-D  (ISO)
2,6-dinitrotoluene  (EXP)
2-(4-chloro-2-methylphenoxy)propanoic acid  (ISO)
2-butoxyethanol  (ISO)
3,3',5-triiodo-L-thyronine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetyl-CoA  (EXP)
aflatoxin B1  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (EXP,ISO)
bezafibrate  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
Butoxyacetic acid  (EXP)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
ciprofibrate  (ISO)
Clinofibrate  (EXP)
clofibrate  (EXP,ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dichloroacetic acid  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
epoxiconazole  (ISO)
Ethoxyacetic acid  (EXP)
etomoxir  (EXP)
fenofibrate  (EXP,ISO)
finasteride  (EXP)
flutamide  (EXP,ISO)
folic acid  (ISO)
gemfibrozil  (EXP)
glafenine  (EXP)
glycidyl methacrylate  (ISO)
GW 7647  (ISO)
indole-3-methanol  (EXP)
indometacin  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lamivudine  (ISO)
leflunomide  (EXP)
mecoprop  (ISO)
mercury dichloride  (EXP)
methimazole  (EXP)
methoxyacetic acid  (EXP)
monosodium L-glutamate  (ISO)
Muraglitazar  (EXP)
N-acetyl-L-cysteine  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
nefazodone  (EXP)
nicardipine  (EXP)
nickel atom  (ISO)
nimesulide  (EXP)
okadaic acid  (ISO)
orphenadrine  (EXP)
ozone  (EXP,ISO)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenformin  (EXP)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
pravastatin  (EXP,ISO)
rotenone  (EXP)
selenium atom  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sulforaphane  (EXP)
tert-butyl hydroperoxide  (ISO)
Tesaglitazar  (EXP)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP)
tetracycline  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (ISO)
Tridiphane  (ISO)
triphenyl phosphate  (EXP,ISO)
triptonide  (ISO)
troglitazone  (EXP)
tunicamycin  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
zaragozic acid A  (EXP,ISO)
zidovudine  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Redesign of carnitine acetyltransferase specificity by protein engineering. Cordente AG, etal., J Biol Chem 2004 Aug 6;279(32):33899-908. Epub 2004 May 21.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2351134   PMID:12477932   PMID:14651853   PMID:15099582   PMID:15489334   PMID:16681386   PMID:18614015   PMID:18839069   PMID:20178365   PMID:20833797   PMID:22607230   PMID:23485643  
PMID:24395925   PMID:26316108  


Genomics

Comparative Map Data
Crat
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8334,073,504 - 34,087,099 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl334,073,506 - 34,087,099 (-)EnsemblGRCr8
mRatBN7.2313,675,684 - 13,689,282 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl313,675,684 - 13,689,255 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx316,747,217 - 16,760,812 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0325,332,179 - 25,345,774 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0323,578,162 - 23,591,743 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.038,967,984 - 8,981,959 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl38,968,417 - 8,981,362 (-)Ensemblrn6Rnor6.0
Rnor_5.0314,320,758 - 14,334,741 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.439,447,585 - 9,461,180 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera38,442,229 - 8,455,824 (-)NCBICelera
RGSC_v3.139,447,886 - 9,461,480 (-)NCBI
Cytogenetic Map3p12NCBI
CRAT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389129,094,794 - 129,110,793 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9129,094,142 - 129,111,313 (-)Ensemblhg38GRCh38
GRCh379131,857,073 - 131,873,072 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369130,896,894 - 130,912,904 (-)NCBIBuild 36Build 36hg18NCBI36
Build 349128,936,628 - 128,952,637NCBI
Celera9102,509,370 - 102,525,353 (-)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9101,464,043 - 101,480,035 (-)NCBIHuRef
CHM1_19132,007,896 - 132,023,887 (-)NCBICHM1_1
T2T-CHM13v2.09141,298,255 - 141,314,668 (-)NCBIT2T-CHM13v2.0
Crat
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39230,290,483 - 30,305,602 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl230,290,483 - 30,305,825 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38230,400,476 - 30,416,017 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl230,400,471 - 30,415,813 (-)Ensemblmm10GRCm38
MGSCv37230,255,996 - 30,271,268 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36230,222,485 - 30,237,757 (-)NCBIMGSCv36mm8
Celera230,105,381 - 30,120,546 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map221.69NCBI
Crat
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555701,417,608 - 1,428,720 (-)Ensembl
ChiLan1.0NW_0049555701,417,608 - 1,428,720 (-)NCBIChiLan1.0ChiLan1.0
CRAT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21110,240,748 - 10,256,782 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1910,243,094 - 10,259,128 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09100,220,019 - 100,236,061 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19128,880,057 - 128,896,484 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9128,880,057 - 128,896,484 (-)EnsemblpanPan2panpan1.1
CRAT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1954,566,708 - 54,580,301 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl954,566,407 - 54,580,025 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha953,762,362 - 53,775,887 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0955,462,309 - 55,475,915 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl955,462,359 - 55,498,279 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1954,248,963 - 54,262,568 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0954,560,854 - 54,574,458 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0954,654,564 - 54,668,171 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Crat
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947196,755,044 - 196,768,721 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648716,523,571 - 16,537,248 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648716,523,571 - 16,537,242 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRAT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1269,386,650 - 269,401,331 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11269,387,430 - 269,401,334 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21303,403,630 - 303,417,527 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CRAT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1129,057,365 - 9,072,692 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl129,058,824 - 9,072,813 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666096491,149 - 506,483 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Crat
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247606,002,568 - 6,013,491 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247606,002,032 - 6,013,489 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Crat
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v155,215,081 - 5,228,951 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Crat
88 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:93
Count of miRNA genes:77
Interacting mature miRNAs:83
Transcripts:ENSRNOT00000065128
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32905627547904329Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10450811Scl73Serum cholesterol level QTL 734.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat
10450808Scl72Serum cholesterol level QTL 724.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
10450806Scl71Serum cholesterol level QTL 715.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)32862533967641995Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)3612543751125437Rat
8693641Alc30Alcohol consumption QTL 3020.739drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)33083238444921701Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3136721849Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3655634751556347Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31527234860272348Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)32905627547904329Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000065128   ⟹   ENSRNOP00000063089
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl334,073,506 - 34,087,099 (-)Ensembl
mRatBN7.2 Ensembl313,675,684 - 13,689,255 (-)Ensembl
Rnor_6.0 Ensembl38,968,417 - 8,979,889 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000086717   ⟹   ENSRNOP00000075070
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl334,073,506 - 34,084,642 (-)Ensembl
mRatBN7.2 Ensembl313,675,684 - 13,687,360 (-)Ensembl
Rnor_6.0 Ensembl38,968,616 - 8,981,362 (-)Ensembl
RefSeq Acc Id: NM_001004085   ⟹   NP_001004085
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,073,504 - 34,087,099 (-)NCBI
mRatBN7.2313,675,684 - 13,689,282 (-)NCBI
Rnor_6.038,967,989 - 8,981,584 (-)NCBI
Rnor_5.0314,320,758 - 14,334,741 (-)NCBI
RGSC_v3.439,447,585 - 9,461,180 (-)RGD
Celera38,442,229 - 8,455,824 (-)RGD
Sequence:
RefSeq Acc Id: XM_063283951   ⟹   XP_063140021
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,073,504 - 34,086,989 (-)NCBI
RefSeq Acc Id: XM_063283952   ⟹   XP_063140022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,073,504 - 34,085,187 (-)NCBI
RefSeq Acc Id: XM_063283953   ⟹   XP_063140023
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8334,079,881 - 34,086,988 (-)NCBI
RefSeq Acc Id: NP_001004085   ⟸   NM_001004085
- UniProtKB: Q704S8 (UniProtKB/Swiss-Prot),   A0A0H2UI21 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000063089   ⟸   ENSRNOT00000065128
Ensembl Acc Id: ENSRNOP00000075070   ⟸   ENSRNOT00000086717
RefSeq Acc Id: XP_063140021   ⟸   XM_063283951
- Peptide Label: isoform X1
- UniProtKB: A0A0H2UI21 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140022   ⟸   XM_063283952
- Peptide Label: isoform X2
- UniProtKB: A0A0H2UI21 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140023   ⟸   XM_063283953
- Peptide Label: isoform X3
Protein Domains
Choline/carnitine acyltransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q704S8-F1-model_v2 AlphaFold Q704S8 1-626 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691959
Promoter ID:EPDNEW_R2484
Type:initiation region
Name:Crat_1
Description:carnitine O-acetyltransferase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.038,981,323 - 8,981,383EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303031 AgrOrtholog
BioCyc Gene G2FUF-50212 BioCyc
Ensembl Genes ENSRNOG00000018145 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000065128 ENTREZGENE
  ENSRNOT00000086717 ENTREZGENE
Gene3D-CATH 3.30.559.10 UniProtKB/Swiss-Prot
  3.30.559.70 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7133847 IMAGE-MGC_LOAD
InterPro Carn_acyl_trans UniProtKB/Swiss-Prot
  CAT-like_dom_sf UniProtKB/Swiss-Prot
  Cho/carn_acyl_trans UniProtKB/Swiss-Prot
  Cho/carn_acyl_trans_2 UniProtKB/Swiss-Prot
KEGG Report rno:311849 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94385 IMAGE-MGC_LOAD
NCBI Gene 311849 ENTREZGENE
PANTHER CARNITINE O-ACETYLTRANSFERASE UniProtKB/Swiss-Prot
  PTHR22589 UniProtKB/Swiss-Prot
Pfam Carn_acyltransf UniProtKB/Swiss-Prot
PhenoGen Crat PhenoGen
PROSITE ACYLTRANSF_C_1 UniProtKB/Swiss-Prot
  ACYLTRANSF_C_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018145 RatGTEx
Superfamily-SCOP CoA-dependent acyltransferases UniProtKB/Swiss-Prot
UniProt A0A0H2UI21 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2RAJ5_RAT UniProtKB/TrEMBL
  A6JTY8_RAT UniProtKB/TrEMBL
  A6JTY9_RAT UniProtKB/TrEMBL
  CACP_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-01 Crat  carnitine O-acetyltransferase  Crat  carnitine acetyltransferase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Crat  carnitine acetyltransferase      Symbol and Name status set to approved 1299863 APPROVED
2005-02-14 Crat  carnitine acetyltransferase      Symbol and Name status set to provisional 70820 PROVISIONAL