Osmr (oncostatin M receptor) - Rat Genome Database

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Gene: Osmr (oncostatin M receptor) Rattus norvegicus
Analyze
Symbol: Osmr
Name: oncostatin M receptor
RGD ID: 1302983
Description: Predicted to enable several functions, including ciliary neurotrophic factor receptor binding activity; cytokine receptor activity; and growth factor binding activity. Predicted to contribute to oncostatin-M receptor activity. Predicted to be involved in oncostatin-M-mediated signaling pathway and positive regulation of cell population proliferation. Predicted to be located in apical plasma membrane. Predicted to be part of oncostatin-M receptor complex. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in primary localized cutaneous amyloidosis 1. Orthologous to human OSMR (oncostatin M receptor); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: IL-31 receptor subunit beta; IL-31R subunit beta; IL-31R-beta; IL-31RB; interleukin-31 receptor subunit beta; oncostatin M specific receptor; oncostatin-M specific receptor subunit beta; oncostatin-M-specific receptor subunit beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8257,634,517 - 57,688,802 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl257,634,517 - 57,688,561 (-)EnsemblGRCr8
mRatBN7.2255,907,119 - 55,961,373 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl255,907,132 - 55,961,262 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx263,008,784 - 63,049,624 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0261,083,588 - 61,124,605 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0256,084,784 - 56,125,624 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0256,107,491 - 56,163,522 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl256,110,777 - 56,151,531 (-)Ensemblrn6Rnor6.0
Rnor_5.0275,849,931 - 75,903,395 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4256,080,700 - 56,121,463 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera251,528,960 - 51,569,586 (-)NCBICelera
RGSC_v3.1256,008,932 - 56,049,696 (-)NCBI
Cytogenetic Map2q16NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,2'-Methylenebis(4-methyl-6-tert-butylphenol)  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-acetamidofluorene  (EXP)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-nitroquinoline N-oxide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzo[k]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
choline  (ISO)
chromium(6+)  (ISO)
ciglitazone  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
crocidolite asbestos  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dextran sulfate  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
disulfiram  (ISO)
docebenone  (ISO)
dorsomorphin  (ISO)
doxifluridine  (ISO)
doxorubicin  (ISO)
doxycycline  (ISO)
endosulfan  (EXP)
ethylparaben  (ISO)
fluoranthene  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (EXP)
gefitinib  (ISO)
Genipin  (ISO)
gentamycin  (EXP)
glyphosate  (ISO)
irinotecan  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (EXP,ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorobutyric acid  (ISO)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
phosgene  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
prostaglandin E2  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
sarin  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
Tributyltin oxide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Cloning and characterization of a specific receptor for mouse oncostatin M. Lindberg RA, etal., Mol Cell Biol 1998 Jun;18(6):3357-67.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8999038   PMID:9920829   PMID:15743783   PMID:21182835   PMID:21912637  


Genomics

Comparative Map Data
Osmr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8257,634,517 - 57,688,802 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl257,634,517 - 57,688,561 (-)EnsemblGRCr8
mRatBN7.2255,907,119 - 55,961,373 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl255,907,132 - 55,961,262 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx263,008,784 - 63,049,624 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0261,083,588 - 61,124,605 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0256,084,784 - 56,125,624 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0256,107,491 - 56,163,522 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl256,110,777 - 56,151,531 (-)Ensemblrn6Rnor6.0
Rnor_5.0275,849,931 - 75,903,395 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4256,080,700 - 56,121,463 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera251,528,960 - 51,569,586 (-)NCBICelera
RGSC_v3.1256,008,932 - 56,049,696 (-)NCBI
Cytogenetic Map2q16NCBI
OSMR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38538,846,012 - 38,945,579 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl538,845,852 - 38,945,596 (+)Ensemblhg38GRCh38
GRCh37538,846,114 - 38,935,743 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36538,881,893 - 38,970,159 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34538,881,892 - 38,970,159NCBI
Celera538,732,864 - 38,822,240 (+)NCBICelera
Cytogenetic Map5p13.1NCBI
HuRef538,797,948 - 38,887,280 (+)NCBIHuRef
CHM1_1538,847,894 - 38,937,695 (+)NCBICHM1_1
T2T-CHM13v2.0539,095,483 - 39,194,986 (+)NCBIT2T-CHM13v2.0
Osmr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39156,843,049 - 6,904,434 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl156,843,058 - 6,904,450 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38156,813,568 - 6,874,968 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl156,813,577 - 6,874,969 (-)Ensemblmm10GRCm38
MGSCv37156,763,577 - 6,824,313 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36156,760,805 - 6,821,498 (-)NCBIMGSCv36mm8
Celera156,661,996 - 6,722,694 (-)NCBICelera
Cytogenetic Map15A1NCBI
cM Map153.3NCBI
Osmr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542623,395,268 - 23,464,130 (+)Ensembl
ChiLan1.0NW_00495542623,395,286 - 23,465,078 (+)NCBIChiLan1.0ChiLan1.0
OSMR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2471,400,375 - 71,489,683 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1569,553,891 - 69,643,334 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0571,437,589 - 71,525,521 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1576,478,261 - 76,564,321 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl576,478,699 - 76,543,263 (-)EnsemblpanPan2panpan1.1
OSMR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1470,016,384 - 70,067,098 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl470,018,022 - 70,055,216 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha469,692,776 - 69,743,417 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0470,532,608 - 70,583,192 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl470,532,721 - 70,570,914 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1470,281,515 - 70,332,102 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0470,394,095 - 70,444,696 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0470,933,024 - 70,983,594 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Osmr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213227,990,264 - 228,053,037 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365183,318,803 - 3,382,184 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365183,320,057 - 3,381,518 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OSMR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1624,041,567 - 24,102,177 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11624,041,312 - 24,101,842 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21625,288,919 - 25,348,918 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OSMR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1437,661,333 - 37,756,714 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl437,684,090 - 37,754,473 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607128,029,339 - 28,124,980 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Osmr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475915,982,678 - 16,035,040 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475915,980,694 - 16,052,683 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Osmr
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13173,632,937 - 173,687,135 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Osmr
309 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:109
Count of miRNA genes:90
Interacting mature miRNAs:100
Transcripts:ENSRNOT00000040847
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21332504158325041Rat
7387318Stl32Serum triglyceride level QTL 323.20.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)22411781369117813Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23675034481750344Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1579916Bp270Blood pressure QTL 2700.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21605188361051883Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22203804467038044Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)240306867124537199Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22888999173889991Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)241801363104744824Rat
1331764Bp205Blood pressure QTL 2053.476arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21436870759368707Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24490435585286097Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1300155Bp174Blood pressure QTL 1744.09arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)244537979112567334Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979159440891Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266683465677Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)25126685996266859Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)238426449111295694Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)230219200171802126Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21822713763227137Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)230219200171802126Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23686864381868643Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)24490435589904355Rat
1582246Cm60Cardiac mass QTL 605.8heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)23326999678269996Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266673652666Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 56 59 6 320 156 11 140 81 92 31 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000040847   ⟹   ENSRNOP00000039644
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl257,634,517 - 57,688,561 (-)Ensembl
mRatBN7.2 Ensembl255,907,132 - 55,961,262 (-)Ensembl
Rnor_6.0 Ensembl256,110,777 - 56,151,531 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000080677   ⟹   ENSRNOP00000070547
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl256,110,777 - 56,151,531 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000158977   ⟹   ENSRNOP00000099738
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl257,634,517 - 57,688,561 (-)Ensembl
RefSeq Acc Id: NM_001005384   ⟹   NP_001005384
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,634,517 - 57,688,561 (-)NCBI
mRatBN7.2255,907,119 - 55,961,167 (-)NCBI
Rnor_6.0256,110,777 - 56,151,531 (-)NCBI
Rnor_5.0275,849,931 - 75,903,395 (-)NCBI
RGSC_v3.4256,080,700 - 56,121,463 (-)RGD
Celera251,528,960 - 51,569,586 (-)RGD
Sequence:
RefSeq Acc Id: XM_039102190   ⟹   XP_038958118
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,634,519 - 57,688,802 (-)NCBI
mRatBN7.2255,907,119 - 55,961,371 (-)NCBI
RefSeq Acc Id: XM_039102191   ⟹   XP_038958119
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,634,519 - 57,688,766 (-)NCBI
mRatBN7.2255,907,119 - 55,961,371 (-)NCBI
RefSeq Acc Id: XM_039102192   ⟹   XP_038958120
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,634,519 - 57,688,766 (-)NCBI
mRatBN7.2255,907,119 - 55,961,371 (-)NCBI
RefSeq Acc Id: XM_039102193   ⟹   XP_038958121
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,634,519 - 57,688,766 (-)NCBI
mRatBN7.2255,907,119 - 55,961,371 (-)NCBI
RefSeq Acc Id: XM_039102194   ⟹   XP_038958122
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,634,519 - 57,688,766 (-)NCBI
mRatBN7.2255,907,119 - 55,961,371 (-)NCBI
RefSeq Acc Id: XM_039102195   ⟹   XP_038958123
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,634,519 - 57,688,767 (-)NCBI
mRatBN7.2255,907,119 - 55,961,372 (-)NCBI
RefSeq Acc Id: XM_039102196   ⟹   XP_038958124
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,634,519 - 57,688,767 (-)NCBI
mRatBN7.2255,907,119 - 55,961,372 (-)NCBI
RefSeq Acc Id: XM_039102197   ⟹   XP_038958125
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,634,519 - 57,688,767 (-)NCBI
mRatBN7.2255,907,119 - 55,961,373 (-)NCBI
RefSeq Acc Id: XM_039102198   ⟹   XP_038958126
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8257,634,519 - 57,688,765 (-)NCBI
mRatBN7.2255,909,021 - 55,961,371 (-)NCBI
RefSeq Acc Id: NP_001005384   ⟸   NM_001005384
- Peptide Label: precursor
- UniProtKB: Q65Z14 (UniProtKB/Swiss-Prot),   F1LP92 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070547   ⟸   ENSRNOT00000080677
Ensembl Acc Id: ENSRNOP00000039644   ⟸   ENSRNOT00000040847
RefSeq Acc Id: XP_038958125   ⟸   XM_039102197
- Peptide Label: isoform X4
- UniProtKB: Q65Z14 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038958123   ⟸   XM_039102195
- Peptide Label: isoform X2
- UniProtKB: Q65Z14 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038958124   ⟸   XM_039102196
- Peptide Label: isoform X3
- UniProtKB: Q65Z14 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038958118   ⟸   XM_039102190
- Peptide Label: isoform X1
- UniProtKB: Q65Z14 (UniProtKB/Swiss-Prot),   F1LP92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958122   ⟸   XM_039102194
- Peptide Label: isoform X1
- UniProtKB: Q65Z14 (UniProtKB/Swiss-Prot),   F1LP92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958120   ⟸   XM_039102192
- Peptide Label: isoform X1
- UniProtKB: Q65Z14 (UniProtKB/Swiss-Prot),   F1LP92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958121   ⟸   XM_039102193
- Peptide Label: isoform X1
- UniProtKB: Q65Z14 (UniProtKB/Swiss-Prot),   F1LP92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958119   ⟸   XM_039102191
- Peptide Label: isoform X1
- UniProtKB: Q65Z14 (UniProtKB/Swiss-Prot),   F1LP92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958126   ⟸   XM_039102198
- Peptide Label: isoform X5
- UniProtKB: Q65Z14 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSRNOP00000099738   ⟸   ENSRNOT00000158977
Protein Domains
Fibronectin type-III

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q65Z14-F1-model_v2 AlphaFold Q65Z14 1-962 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1302983 AgrOrtholog
BioCyc Gene G2FUF-54149 BioCyc
Ensembl Genes ENSRNOG00000033192 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000040847 ENTREZGENE
  ENSRNOT00000158977 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
InterPro FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  Hematopoietin_rcpt_Gp130_CS UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  LIF-R-like_Ig-like UniProtKB/Swiss-Prot
  LIFR_D2 UniProtKB/Swiss-Prot
  Type1_Cytokine_Rcpt_Type2 UniProtKB/Swiss-Prot
KEGG Report rno:310132 UniProtKB/Swiss-Prot
NCBI Gene 310132 ENTREZGENE
PANTHER INTERLEUKIN-27 RECEPTOR SUBUNIT ALPHA UniProtKB/Swiss-Prot
  INTERLEUKIN-27 RECEPTOR SUBUNIT ALPHA UniProtKB/Swiss-Prot
Pfam fn3 UniProtKB/Swiss-Prot
  LIF-R_Ig-like UniProtKB/Swiss-Prot
  LIFR_D2 UniProtKB/Swiss-Prot
PhenoGen Osmr PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot
  HEMATOPO_REC_L_F2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000033192 RatGTEx
SMART FN3 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49265 UniProtKB/Swiss-Prot
UniProt A0ABK0L5G1_RAT UniProtKB/TrEMBL
  A6KGG2_RAT UniProtKB/TrEMBL
  F1LP92 ENTREZGENE, UniProtKB/TrEMBL
  OSMR_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Osmr  oncostatin M receptor    oncostatin M specific receptor  Name updated 1299863 APPROVED
2005-02-14 Osmr  oncostatin M specific receptor      Symbol and Name status set to provisional 70820 PROVISIONAL