Thpol1 (thrombopoietin like 1) - Rat Genome Database

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Gene: Thpol1 (thrombopoietin like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Thpol1
Name: thrombopoietin like 1
RGD ID: 11455920
Description: Human ortholog(s) of this gene implicated in aplastic anemia; congenital amegakaryocytic thrombocytopenia 2; essential thrombocythemia; thrombocytopenia; and thrombocytosis. Orthologous to human THPO (thrombopoietin).
Type: protein-coding
Previously known as: LOC108348162; NEWGENE_621438; Thpo; thrombopoietin
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
UTH_Rnor_SHR_Utx1188,905,624 - 88,910,879 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01181,559,040 - 81,564,295 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01180,620,102 - 80,625,357 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01183,867,549 - 83,874,670 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1182,848,853 - 82,852,425 (+)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl1183,868,655 - 83,873,910 (+)Ensemblrn6Rnor6.0
Cytogenetic Map11q23NCBI



Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.

Genomics


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
22 11 37 168 112 110 77 27 77 12 299 102 11 137 91 98 33 6 6

Sequence


Ensembl Acc Id: ENSRNOT00000072402   ⟹   ENSRNOP00000067269
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1193,686,834 - 93,692,573 (+)Ensembl
mRatBN7.2 Ensembl1180,182,820 - 80,188,167 (+)Ensembl
Rnor_6.0 Ensembl1183,868,655 - 83,873,910 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000073743   ⟹   ENSRNOP00000065517
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1182,848,853 - 82,852,425 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000145928   ⟹   ENSRNOP00000111405
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1193,687,318 - 93,693,320 (+)Ensembl
RefSeq Acc Id: XM_008768827   ⟹   XP_008767049
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01183,868,608 - 83,874,670 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008768828   ⟹   XP_008767050
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01183,868,600 - 83,874,670 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008768829   ⟹   XP_008767051
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01183,867,549 - 83,874,670 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598180   ⟹   XP_017453669
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01183,867,549 - 83,874,670 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598181   ⟹   XP_017453670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01183,868,600 - 83,874,670 (+)NCBI
Sequence:
RefSeq Acc Id: XP_017453669   ⟸   XM_017598180
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008767051   ⟸   XM_008768829
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017453670   ⟸   XM_017598181
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008767050   ⟸   XM_008768828
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008767049   ⟸   XM_008768827
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSRNOP00000067269   ⟸   ENSRNOT00000072402
Ensembl Acc Id: ENSRNOP00000065517   ⟸   ENSRNOT00000073743
Ensembl Acc Id: ENSRNOP00000111405   ⟸   ENSRNOT00000145928

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698275
Promoter ID:EPDNEW_R8793
Type:initiation region
Name:Thpol1_1
Description:thrombopoietin like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01183,868,614 - 83,868,674EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:11455920 AgrOrtholog
Ensembl Genes ENSRNOG00000046850 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000050172 Ensembl
Ensembl Transcript ENSRNOT00000072402.3 UniProtKB/TrEMBL
  ENSRNOT00000145928.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.10 UniProtKB/TrEMBL
InterPro 4_helix_cytokine-like_core UniProtKB/TrEMBL
  EPO/TPO_CS UniProtKB/TrEMBL
  EPO_TPO UniProtKB/TrEMBL
  Thrombopoietin UniProtKB/TrEMBL
NCBI Gene Thpo ENTREZGENE
PANTHER PTHR10560 UniProtKB/TrEMBL
  THROMBOPOIETIN UniProtKB/TrEMBL
Pfam EPO_TPO UniProtKB/TrEMBL
PhenoGen Thpol1 PhenoGen
PRINTS THROMBOPTN UniProtKB/TrEMBL
PROSITE EPO_TPO UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046850 RatGTEx
  ENSRNOG00000050172 RatGTEx
Superfamily-SCOP SSF47266 UniProtKB/TrEMBL
UniProt A0A8L2QZ16_RAT UniProtKB/TrEMBL
  A0ABK0M7F6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-24 Thpol1  thrombopoietin like 1  NEWGENE_621438  thrombopoietin  Name and Symbol changed 629549 APPROVED