Sec61gl4 (SEC61 translocon subunit gamma like 4) - Rat Genome Database

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Pathways
Gene: Sec61gl4 (SEC61 translocon subunit gamma like 4) Rattus norvegicus
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Symbol: Sec61gl4
Name: SEC61 translocon subunit gamma like 4
RGD ID: 11451021
Description: Predicted to enable protein transmembrane transporter activity. Predicted to be involved in intracellular protein transport and protein targeting. Predicted to be located in endoplasmic reticulum membrane.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC108351999; protein transport protein Sec61 subunit gamma pseudogene
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8948,798,425 - 48,799,124 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.2941,302,673 - 41,303,608 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.0945,741,577 - 45,742,515 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Celera939,052,065 - 39,053,003 (-)NCBICelera
Cytogenetic Map9q22NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Variants

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Variants in Sec61gl4
2 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9534647950346479Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9875049253750492Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)93125043268875676Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)92956766474567664Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)94445825685262605Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9621499551214995Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9875049253750492Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)93125043265651574Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9534647950416711Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)92103143049025574Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)93922018684220186Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9621499551214995Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)93145606157460683Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93496059079960590Rat


Expression

RNA-SEQ Expression

ectoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
sensory system
visual system
2 5 8 5 2 3 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_063267797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_063267797   ⟹   XP_063123867
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8948,798,425 - 48,799,124 (-)NCBI
Protein Sequences
Protein RefSeqs XP_063123867 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000006906.4
RefSeq Acc Id: XP_063123867   ⟸   XM_063267797
- UniProtKB: A0A8J8XD56 (UniProtKB/TrEMBL)

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-27758 BioCyc
Ensembl Genes ENSRNOG00000005203 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006906.5 UniProtKB/TrEMBL
Gene3D-CATH Preprotein translocase SecE subunit UniProtKB/TrEMBL
InterPro Prot_translocase_SecE_dom_sf UniProtKB/TrEMBL
  Translocase_Sec61-g UniProtKB/TrEMBL
  Translocase_SecE/Sec61-g UniProtKB/TrEMBL
NCBI Gene LOC108351999 ENTREZGENE
PANTHER SEC61 GAMMA SUBUNIT UniProtKB/TrEMBL
Pfam SecE UniProtKB/TrEMBL
PhenoGen Sec61gl4 PhenoGen
PROSITE SECE_SEC61G UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005203 RatGTEx
Superfamily-SCOP Preprotein translocase SecE subunit UniProtKB/TrEMBL
UniProt A0A8J8XD56 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-16 Sec61gl4  SEC61 translocon subunit gamma like 4  Sec61gl1  Sec61 translocon subunit gamma like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-09-19 Sec61gl1  Sec61 translocon subunit gamma like 1  LOC108351999  protein transport protein Sec61 subunit gamma pseudogene  Symbol and Name Changed 1299863 APPROVED
2016-08-02 LOC108351999  protein transport protein Sec61 subunit gamma pseudogene      Symbol and Name status set to provisional 70820 PROVISIONAL