Ontology Report for Acly


Predicted Confidence:coding
Gene:Acly - ATP citrate lyase
Description:catalyzes the synthesis of cytosolic acetyl-CoA; plays a role in lipid and cholesterol metabolism
 
Ontology Annotations

Molecular Function
TermQualifierEvidenceWithReference NotesSource
ATP citrate synthase activityIDA .. 631761RGD
citrate (pro-3S)-lyase activityISO (from RGD:10065)(from RGD:10065) 1624291PMID:1371749RGD
protein bindingISO (from RGD:10065)(from RGD:10065) 1624291UniProtKB:P19532RGD
protein bindingISO (from RGD:10064)(from RGD:10064) 1624291UniProtKB:Q8CFN5-4RGD

Biological Process
TermQualifierEvidenceWithReference NotesSource
acetyl-CoA biosynthetic processNAS .. 631761RGD
lipid metabolic processIEP .. 631761RGD

Cellular Component
TermQualifierEvidenceWithReference NotesSource
cytosolISO (from RGD:10065)(from RGD:10065) 1624291PMID:1371749RGD
mitochondrionISO (from RGD:10064)(from RGD:10064) 1624291MGI:MGI:3852644|PMID:18614015RGD

Disease
TermQualifierEvidenceWithReference NotesSource
Dentin DysplasiaISS .. 1300342RGD

Phenotype
TermQualifierEvidenceWithReference NotesSource
abnormal avoidance learning behaviorISS .. 1300238RGD